Reporting Date	Hedge Fund	Shares Held	Market Value	% of Portfolio	Quarterly Change in Shares	Ownership in Company
3/11/2024	Vanguard Group Inc.	1,601,834	$2.18M	0.0%	+1.7%	3.594%
2/15/2024	Vanguard Group Inc.	1,601,834	$2.18M	0.0%	+1.7%	3.594%
2/15/2024	Newtyn Management LLC	2,734,175	$3.72M	0.7%	+36.7%	6.135%
2/15/2024	Bridgeway Capital Management LLC	239,987	$0.33M	0.0%	+62.8%	0.538%
2/14/2024	ADAR1 Capital Management LLC	50,147	$68K	0.0%	N/A	0.113%
2/14/2024	Vazirani Asset Management LLC	650,000	$0.88M	3.6%	+38.8%	1.458%
2/13/2024	GABELLI & Co INVESTMENT ADVISERS INC.	353,000	$0.48M	0.1%	N/A	0.792%
2/13/2024	Gabelli Funds LLC	343,421	$0.47M	0.0%	N/A	0.771%
1/12/2024	FNY Investment Advisers LLC	400,000	$0.54M	0.6%	+77.8%	0.897%
12/18/2023	Vanguard Group Inc.	1,574,834	$2.43M	0.0%	+33.3%	3.533%
11/15/2023	Affinity Asset Advisors LLC	500,000	$0.77M	0.2%	N/A	1.123%
11/14/2023	Terrapin Asset Management LLC	558,787	$0.86M	1.0%	N/A	1.255%
11/14/2023	Newtyn Management LLC	2,000,000	$3.08M	0.8%	N/A	4.491%
11/13/2023	Aldebaran Capital LLC	470,130	$0.72M	0.7%	N/A	1.056%
11/13/2023	Acadian Asset Management LLC	1,725,089	$2.66M	0.0%	-2.5%	3.874%
11/3/2023	Private Advisor Group LLC	21,410	$33K	0.0%	N/A	0.048%
10/23/2023	BML Capital Management LLC	4,001,627	$6.16M	5.7%	+1,461.4%	8.986%
10/10/2023	FNY Investment Advisers LLC	225,000	$0.35M	0.2%	N/A	0.505%
8/15/2023	Wells Fargo & Company MN	167,094	$0.16M	0.0%	+21.9%	0.375%
8/15/2023	Boothbay Fund Management LLC	26,896	$26K	0.0%	N/A	0.060%
8/11/2023	Renaissance Technologies LLC	562,567	$0.53M	0.0%	-1.9%	1.276%
8/11/2023	BlackRock Inc.	633,036	$0.60M	0.0%	-54.6%	1.435%
8/11/2023	Geode Capital Management LLC	343,741	$0.33M	0.0%	+4.0%	0.779%
8/11/2023	JPMorgan Chase & Co.	141,759	$0.14M	0.0%	-31.8%	0.321%
7/26/2023	Privium Fund Management B.V.	87,770	$78K	0.0%	N/A	0.199%
7/24/2023	BML Capital Management LLC	256,277	$0.24M	0.2%	N/A	0.581%
5/18/2023	JPMorgan Chase & Co.	207,979	$0.21M	0.0%	+781.3%	0.472%
5/16/2023	Geode Capital Management LLC	330,512	$0.33M	0.0%	-14.4%	0.749%
5/16/2023	Atlas Venture Life Science Advisors LLC	4,541,381	$4.54M	0.6%	+0.5%	10.297%
5/15/2023	Farallon Capital Management LLC	3,116,000	$3.12M	0.0%	+321.1%	7.065%
5/12/2023	Renaissance Technologies LLC	573,367	$0.57M	0.0%	-33.5%	1.300%
5/12/2023	BlackRock Inc.	1,393,369	$1.39M	0.0%	-8.4%	3.159%
5/11/2023	Acadian Asset Management LLC	1,770,147	$1.77M	0.0%	+20.4%	4.014%
5/9/2023	GMT Capital Corp	4,357,859	$4.36M	0.2%	+31.7%	9.882%
5/8/2023	Bailard Inc.	45,492	$45K	0.0%	+76.4%	0.103%
5/3/2023	Privium Fund Management UK Ltd	87,770	$85K	0.1%	-66.7%	0.199%
5/1/2023	Virtu Financial LLC	40,319	$40K	0.0%	N/A	0.091%
4/12/2023	FNY Investment Advisers LLC	26,250	$26K	0.0%	N/A	0.060%
2/24/2023	Natixis	880,000	$0.63M	0.0%	N/A	2.011%
2/15/2023	Millennium Management LLC	688,685	$0.49M	0.0%	-2.9%	1.573%
2/15/2023	Morgan Stanley	543,427	$0.39M	0.0%	+6.2%	1.241%
2/14/2023	Two Sigma Investments LP	317,851	$0.23M	0.0%	-19.0%	0.726%
2/13/2023	Natixis	880,000	$0.62M	0.0%	N/A	2.011%
2/13/2023	Renaissance Technologies LLC	862,267	$0.62M	0.0%	-29.4%	1.970%
2/9/2023	Privium Fund Management UK Ltd	263,304	$0.19M	0.1%	+140.2%	0.602%
2/7/2023	LPL Financial LLC	122,578	$87K	0.0%	N/A	0.280%
2/3/2023	GMT Capital Corp	3,309,859	$2.36M	0.1%	-5.3%	7.562%
11/15/2022	Two Sigma Advisers LP	392,200	$0.25M	0.0%	-31.0%	0.896%
11/15/2022	Two Sigma Investments LP	392,624	$0.25M	0.0%	-17.1%	0.897%
11/15/2022	Vanguard Group Inc.	1,157,314	$0.74M	0.0%	+13.4%	2.644%
11/15/2022	Citadel Advisors LLC	512,182	$0.33M	0.0%	-28.3%	1.170%
11/14/2022	Renaissance Technologies LLC	1,222,141	$0.79M	0.0%	-21.4%	2.792%
11/14/2022	Ergoteles LLC	109,750	$71K	0.0%	-21.1%	0.251%
11/9/2022	SVB Wealth LLC	284,365	$0.18M	0.0%	N/A	0.650%
11/1/2022	Privium Fund Management UK Ltd	109,600	$70K	0.1%	N/A	0.250%
8/18/2022	Goldman Sachs Group Inc.	148,446	$0.14M	0.0%	-45.4%	0.339%
8/15/2022	AQR Capital Management LLC	130,805	$0.12M	0.0%	-73.7%	0.299%
8/15/2022	State Street Corp	140,852	$0.13M	0.0%	-77.5%	0.322%
8/15/2022	Millennium Management LLC	794,522	$0.73M	0.0%	+51.5%	1.815%
8/13/2022	Renaissance Technologies LLC	1,555,800	$1.43M	0.0%	+75.8%	3.561%
8/12/2022	Northern Trust Corp	73,938	$68K	0.0%	-77.0%	0.169%
8/12/2022	BNP Paribas Arbitrage SA	32,108	$30K	0.0%	+931.4%	0.073%
8/11/2022	JPMorgan Chase & Co.	2,120,044	$1.95M	0.0%	+6.3%	4.851%
8/10/2022	GMT Capital Corp	3,494,490	$3.22M	0.2%	+34.7%	7.997%
7/19/2022	Sawtooth Solutions LLC	75,942	$70K	0.0%	N/A	0.174%
7/13/2022	Private Advisor Group LLC	76,718	$71K	0.0%	N/A	0.176%
5/27/2022	Walleye Capital LLC	198,926	$0.26M	0.0%	+37.0%	0.455%
5/17/2022	Walleye Capital LLC	198,926	$0.26M	0.0%	+37.0%	0.455%
5/17/2022	Mirabella Financial Services LLP	31,500	$42K	0.0%	N/A	0.072%
5/16/2022	Goldman Sachs Group Inc.	271,749	$0.36M	0.0%	-80.3%	0.622%
5/16/2022	State Street Corp	625,811	$0.83M	0.0%	-25.4%	1.432%
5/13/2022	Renaissance Technologies LLC	885,100	$1.17M	0.0%	+175.7%	2.026%
5/13/2022	Northern Trust Corp	321,962	$0.43M	0.0%	-6.7%	0.737%
5/13/2022	Charles Schwab Investment Management Inc.	84,117	$0.11M	0.0%	-13.7%	0.193%
5/13/2022	Federated Hermes Inc.	2,449,015	$3.23M	0.0%	-5.6%	5.604%
5/13/2022	Vanguard Group Inc.	1,073,168	$1.42M	0.0%	-36.1%	2.456%
5/13/2022	Dimensional Fund Advisors LP	20,842	$28K	0.0%	-54.7%	0.048%
5/12/2022	BlackRock Inc.	3,788,727	$5M	0.0%	+9.6%	8.671%
5/12/2022	Acadian Asset Management LLC	913,457	$1.20M	0.0%	+161.8%	2.090%
5/12/2022	Penn Mutual Asset Management LLC	37,306	$49K	0.1%	N/A	0.085%
5/12/2022	Connor Clark & Lunn Investment Management Ltd.	150,752	$0.20M	0.0%	+25.8%	0.345%
5/11/2022	JPMorgan Chase & Co.	1,994,391	$2.63M	0.0%	-56.0%	4.564%
5/11/2022	GSA Capital Partners LLP	338,422	$0.45M	0.1%	+55.1%	0.774%
3/3/2022	Walleye Capital LLC	145,159	$0.56M	0.0%	+22.1%	0.333%
2/14/2022	PDT Partners LLC	59,700	$0.23M	0.0%	-18.2%	0.137%
2/14/2022	Point72 Asset Management L.P.	150,000	$0.58M	0.0%	-34.8%	0.344%
2/14/2022	Deep Track Capital LP	1,050,132	$4.04M	0.3%	N/A	2.406%
2/14/2022	Eversept Partners LP	304,989	$1.17M	0.1%	-15.2%	0.699%
2/14/2022	Maven Securities LTD	102,041	$0.39M	0.0%	N/A	0.234%
2/14/2022	GSA Capital Partners LLP	218,137	$0.84M	0.1%	+15.6%	0.500%
2/11/2022	Bioimpact Capital LLC	647,918	$2.49M	0.5%	-24.8%	1.484%
2/10/2022	JPMorgan Chase & Co.	4,536,431	$17.47M	0.0%	-1.6%	10.392%
2/10/2022	Acadian Asset Management LLC	348,953	$1.34M	0.0%	+686.9%	0.799%
2/10/2022	Connor Clark & Lunn Investment Management Ltd.	119,818	$0.46M	0.0%	+79.2%	0.274%
2/8/2022	Northern Trust Corp	345,038	$1.33M	0.0%	-3.7%	0.790%
2/7/2022	SG Americas Securities LLC	10,457	$40K	0.0%	-60.6%	0.024%
1/21/2022	Russell Investments Group Ltd.	33,725	$0.13M	0.0%	-25.2%	0.077%
12/8/2021	Moors & Cabot Inc.	22,200	$0.16M	0.0%	N/A	0.051%
11/16/2021	Squarepoint Ops LLC	29,911	$0.17M	0.0%	+40.7%	0.069%
11/16/2021	Two Sigma Advisers LP	285,300	$1.59M	0.0%	+268.6%	0.654%

Data available starting January 2016

AVROBIO, Inc., a clinical-stage gene therapy company, develops hematopoietic stem cell gene therapies to treat rare diseases in the United States. Its gene therapies employ hematopoietic stem cells that are harvested from the patient and then modified with a lentiviral vector to insert the equivalent of a functional copy of the gene that is mutated in the target disease. The company's pipeline includes AVR-RD-02, which is in phase 1/2 clinical trial for the treatment of Gaucher disease type 1 and 3; AVR-RD-01, which is in phase 2 clinical trials for the treatment of Fabry disease; and AVR-RD-03 that is in preclinical stage for the treatment of Pompe disease. The company was incorporated in 2015 and is headquartered in Cambridge, Massachusetts.

Today's Range

Now: $1.24

$1.22

$1.26

50 Day Range

MA: $1.28

$1.22

$1.34

52 Week Range

Now: $1.24

$0.57

$1.70

Volume

36,515 shs

Average Volume

280,783 shs

Market Capitalization

$55.63 million

P/E Ratio

N/A

Dividend Yield

N/A

Beta

1.22

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