PRTA Insider Trading

Insider Ownership Percentage: 31.20%
Insider Buying (Last 12 Months): $30,840,598.72
Insider Selling (Last 12 Months): $20,938,312.82

Prothena Insider Trading History Chart

This chart shows the insider buying and selling history at Prothena by year and by quarter.

Skip ChartChart Data in Insider Trading History Table

Prothena Share Price & Price History

Current Price: $48.23
Price Change: Price Increase of +0.57 (1.20%)
As of 03/31/2023 12:56 PM ET

This chart shows the closing price history over time for PRTA up to the past year.

Skip Chart and Table DataPrice Data in Insider Trading History Table
Days: 30 | 90 | 365

Prothena Insider Trading History

Transaction DateInsider NameTitleBuy/SellNumber of SharesAverage Share PriceTotal TransactionShares Held After TransactionDetails
3/20/2023Karin L. WalkerCAOSell5,000$47.72$238,600.00View SEC Filing Icon  
3/15/2023Karin L. WalkerCAOSell20,000$48.42$968,400.00View SEC Filing Icon  
3/15/2023Michael J. MalecekinsiderSell15,000$48.44$726,600.00View SEC Filing Icon  
3/15/2023Tran NguyenCFOSell10,000$48.43$484,300.003,200View SEC Filing Icon  
2/15/2023Tran NguyenCFOSell10,000$53.34$533,400.003,200View SEC Filing Icon  
1/18/2023Tran NguyenCFOSell10,000$55.53$555,300.003,200View SEC Filing Icon  
1/10/2023Shane CookeDirectorSell5,000$52.92$264,600.00View SEC Filing Icon  
1/5/2023Richard T CollierDirectorSell5,000$52.67$263,350.001,219View SEC Filing Icon  
1/3/2023Lars EkmanInsiderSell15,834$55.98$886,387.32243View SEC Filing Icon  
12/21/2022Tran NguyenCFOSell10,000$58.97$589,700.003,200View SEC Filing Icon  
12/12/2022Shane CookeDirectorSell5,000$61.04$305,200.00View SEC Filing Icon  
12/5/2022Richard T CollierDirectorSell5,000$62.07$310,350.001,219View SEC Filing Icon  
11/30/2022Michael J. MalecekinsiderSell5,000$62.28$311,400.00243View SEC Filing Icon  
11/23/2022Tran NguyenCFOSell10,000$61.09$610,900.003,200View SEC Filing Icon  
11/18/2022Karin L. WalkerCAOSell10,000$57.07$570,700.00View SEC Filing Icon  
11/10/2022Shane CookeDirectorSell5,000$56.17$280,850.00View SEC Filing Icon  
11/7/2022Richard T CollierDirectorSell5,000$55.62$278,100.001,219View SEC Filing Icon  
11/1/2022Lars EkmanInsiderSell15,833$62.88$995,579.04243View SEC Filing Icon  
10/27/2022Michael J. MalecekinsiderSell20,000$62.00$1,240,000.00View SEC Filing Icon  
10/24/2022Karin L. WalkerCAOSell20,000$57.23$1,144,600.00View SEC Filing Icon  
10/19/2022Tran NguyenCFOSell10,000$56.44$564,400.003,200View SEC Filing Icon  
10/10/2022Shane CookeDirectorSell5,000$55.91$279,550.00View SEC Filing Icon  
10/5/2022Richard T CollierDirectorSell5,000$57.92$289,600.001,219View SEC Filing Icon  
10/3/2022Hideki GarreninsiderSell4,000$60.90$243,600.00243View SEC Filing Icon  
9/28/2022Gene G KinneyCEOSell16,412$53.38$876,072.5612,793View SEC Filing Icon  
9/28/2022Lars EkmanInsiderSell31,666$48.09$1,522,817.94243View SEC Filing Icon  
9/28/2022Shane CookeDirectorSell10,000$48.09$480,900.001,219View SEC Filing Icon  
9/21/2022Gene G KinneyCEOSell2,720$32.02$87,094.4012,793View SEC Filing Icon  
9/21/2022Tran NguyenCFOSell10,000$30.75$307,500.003,200View SEC Filing Icon  
9/15/2022Hideki GarreninsiderSell4,000$30.00$120,000.00View SEC Filing Icon  
8/24/2022Tran NguyenCFOSell10,000$30.17$301,700.003,200View SEC Filing Icon  
8/17/2022Gene G KinneyCEOSell2,181$32.03$69,857.4312,793View SEC Filing Icon  
8/12/2022Gene G KinneyCEOSell20,284$32.16$652,333.4412,793View SEC Filing Icon  
8/10/2022Gene G KinneyCEOSell991$32.01$31,721.9112,793View SEC Filing Icon  
8/5/2022Gene G KinneyCEOSell21,506$32.83$706,041.9812,793View SEC Filing Icon  
8/1/2022Hideki GarreninsiderSell4,000$30.52$122,080.00View SEC Filing Icon  
7/27/2022Gene G KinneyCEOSell376$32.00$12,032.0012,793View SEC Filing Icon  
7/22/2022Tran NguyenCFOSell7,320$32.55$238,266.003,200View SEC Filing Icon  
7/20/2022Shane CookeDirectorSell15,000$32.90$493,500.00View SEC Filing Icon  
7/20/2022Tran NguyenCFOSell42,120$32.49$1,368,478.803,200View SEC Filing Icon  
7/6/2022Hideki GarreninsiderSell8,000$30.00$240,000.00View SEC Filing Icon  
5/5/2022Ecor1 Capital, LlcMajor ShareholderBuy1,062,736$29.02$30,840,598.7211,584,280View SEC Filing Icon  
4/11/2022Shane CookeDirectorSell5,000$35.08$175,400.00View SEC Filing Icon  
4/5/2022Richard T CollierDirectorSell5,000$39.41$197,050.001,219View SEC Filing Icon  
1/12/2022Ecor1 Capital, LlcMajor ShareholderBuy300,000$37.50$11,250,000.00View SEC Filing Icon  
1/3/2022Dennis J SelkoeDirectorSell5,000$47.45$237,250.00View SEC Filing Icon  
11/23/2021Karin L. WalkerCAOSell4,519$57.88$261,559.72View SEC Filing Icon  
11/19/2021Michael J. MalecekInsiderSell10,000$55.00$550,000.00View SEC Filing Icon  
11/1/2021Carol D. KarpInsiderSell10,000$57.18$571,800.00View SEC Filing Icon  
10/27/2021Michael J. MalecekInsiderSell10,000$58.52$585,200.00View SEC Filing Icon  
10/20/2021Karin L. WalkerCAOSell23,000$60.25$1,385,750.00View SEC Filing Icon  
10/1/2021Carol D. KarpInsiderSell10,000$68.23$682,300.00View SEC Filing Icon  
10/1/2021Dennis J SelkoeDirectorSell5,000$67.84$339,200.00View SEC Filing Icon  
7/30/2021Dennis J. SelkoeDirectorSell5,000$49.47$247,350.006,345View SEC Filing Icon  
7/14/2021Christopher S. HenneyDirectorSell11,108$55.46$616,049.6811,108View SEC Filing Icon  
7/12/2021Christopher S. HenneyDirectorSell23,892$55.51$1,326,244.9217,500View SEC Filing Icon  
6/25/2021Christopher S. HenneyDirectorSell12,000$47.73$572,760.0012,000View SEC Filing Icon  
6/22/2021Wagner M. ZagoInsiderSell115,250$46.15$5,318,787.5015,000View SEC Filing Icon  
3/24/2021Ecor1 Capital, LlcMajor ShareholderBuy875,000$20.75$18,156,250.00View SEC Filing Icon  
2/23/2021Ecor1 Capital, LlcMajor ShareholderBuy44,400$21.05$934,620.00View SEC Filing Icon  
2/18/2021Wagner M. ZagoInsiderSell7,540$25.50$192,270.007,540View SEC Filing Icon  
See Full Table

SEC Filings (Institutional Ownership Changes) for Prothena (NASDAQ:PRTA)

91.72% of Prothena stock is owned by institutions. Institutional ownership can be a sign of analyst confidence in the fundamentals of the stock.

Institutional Buying and Selling by Quarter

This chart shows the instiutional buying and selling at PRTA by year and by quarter.

Skip Institutional Buying and Selling Chart and Table DataRead Chart Data in Institutional Trading History Table

Prothena Institutional Trading History

Reporting DateHedge FundShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
3/27/2023Neo Ivy Capital Management15,120$0.91M0.6%N/A0.029%Search for SEC Filing on Google Icon
2/28/2023Voya Investment Management LLC38,000$2.29M0.0%+38.7%0.079%Search for SEC Filing on Google Icon
2/21/2023Macquarie Group Ltd.28,569$1.72M0.0%+3,195.2%0.059%Search for SEC Filing on Google Icon
2/16/2023Alliancebernstein L.P.44,866$2.70M0.0%-1.1%0.093%Search for SEC Filing on Google Icon
2/16/2023Point72 Middle East FZE791$48K0.0%N/A0.002%Search for SEC Filing on Google Icon
2/15/2023Captrust Financial Advisors3,976$0.24M0.0%N/A0.008%Search for SEC Filing on Google Icon
2/15/2023Kiwi Wealth Investments Limited Partnership7,121$0.43M0.0%-57.9%0.015%Search for SEC Filing on Google Icon
2/15/2023Silverarc Capital Management LLC71,706$4.32M1.2%-31.7%0.148%Search for SEC Filing on Google Icon
2/15/2023State of Wisconsin Investment Board32,995$1.99M0.0%-33.1%0.068%Search for SEC Filing on Google Icon
2/15/2023Schonfeld Strategic Advisors LLC28,128$1.70M0.0%-37.2%0.058%Search for SEC Filing on Google Icon
2/15/2023Squarepoint Ops LLC5,516$0.33M0.0%N/A0.011%Search for SEC Filing on Google Icon
2/15/2023T. Rowe Price Investment Management Inc.927,959$55.91M0.0%+9.4%1.918%Search for SEC Filing on Google Icon
2/15/2023Millennium Management LLC213,610$12.87M0.0%+128.6%0.442%Search for SEC Filing on Google Icon
2/15/2023Morgan Stanley180,403$10.87M0.0%+8.4%0.373%Search for SEC Filing on Google Icon
2/15/2023Man Group plc23,697$1.43M0.0%-53.3%0.049%Search for SEC Filing on Google Icon
2/15/2023Mariner LLC26,927$1.62M0.0%+58.1%0.056%Search for SEC Filing on Google Icon
2/15/2023Norges Bank59,259$3.57M0.0%N/A0.122%Search for SEC Filing on Google Icon
2/15/2023EAM Investors LLC53,346$3.21M0.7%-0.5%0.110%Search for SEC Filing on Google Icon
2/15/2023First Light Asset Management LLC1,535,599$92.52M8.6%-0.2%3.174%Search for SEC Filing on Google Icon
2/15/2023Algert Global LLC19,203$1.16M0.1%+121.5%0.040%Search for SEC Filing on Google Icon
2/15/2023Alps Advisors Inc.32,776$1.98M0.0%+28.1%0.068%Search for SEC Filing on Google Icon
2/15/2023Avidity Partners Management LP2,953,000$177.92M3.9%+50.1%6.104%Search for SEC Filing on Google Icon
2/14/2023Point72 Asset Management L.P.311,500$18.77M0.1%+85.0%0.644%Search for SEC Filing on Google Icon
2/14/2023Price T Rowe Associates Inc. MD3,205,903$193.16M0.0%+7.5%6.627%Search for SEC Filing on Google Icon
2/14/2023Putnam Investments LLC65,394$3.94M0.0%+343.2%0.135%Search for SEC Filing on Google Icon
2/14/2023Amundi2,781$0.16M0.0%-8.2%0.006%Search for SEC Filing on Google Icon
2/14/2023Two Sigma Advisers LP327,000$19.70M0.1%-2.4%0.676%Search for SEC Filing on Google Icon
2/14/2023Two Sigma Investments LP203,435$12.26M0.0%+49.9%0.421%Search for SEC Filing on Google Icon
2/14/2023Pura Vida Investments LLC64,000$3.86M0.2%N/A0.132%Search for SEC Filing on Google Icon
2/14/2023Granahan Investment Management LLC199,926$12.05M0.4%+41.7%0.413%Search for SEC Filing on Google Icon
2/14/2023Engineers Gate Manager LP4,135$0.25M0.0%N/A0.009%Search for SEC Filing on Google Icon
2/13/2023Platinum Investment Management Ltd.41,508$2.50M0.1%-15.1%0.086%Search for SEC Filing on Google Icon
2/13/2023Charles Schwab Investment Management Inc.300,850$18.13M0.0%+5.3%0.622%Search for SEC Filing on Google Icon
2/13/2023Deutsche Bank AG21,898$1.32M0.0%+34.5%0.045%Search for SEC Filing on Google Icon
2/13/2023Wells Fargo & Company MN10,665$0.64M0.0%-14.7%0.022%Search for SEC Filing on Google Icon
2/13/2023Barclays PLC79,339$4.78M0.0%+16.6%0.164%Search for SEC Filing on Google Icon
2/13/2023Renaissance Technologies LLC474,900$28.61M0.0%-25.4%0.982%Search for SEC Filing on Google Icon
2/13/2023The Manufacturers Life Insurance Company 55,062$3.29M0.0%+3.8%0.114%Search for SEC Filing on Google Icon
2/13/2023Credit Suisse AG38,887$2.34M0.0%+24.3%0.080%Search for SEC Filing on Google Icon
2/13/2023Geode Capital Management LLC715,601$43.11M0.0%+12.6%1.479%Search for SEC Filing on Google Icon
2/13/2023Finepoint Capital LP322,900$19.46M6.3%+5.7%0.667%Search for SEC Filing on Google Icon
2/13/2023American Century Companies Inc.4,167$0.25M0.0%N/A0.009%Search for SEC Filing on Google Icon
2/13/2023Advisory Research Inc.7,120$0.43M0.0%N/A0.015%Search for SEC Filing on Google Icon
2/13/2023Capital Fund Management S.A.29,772$1.79M0.0%N/A0.062%Search for SEC Filing on Google Icon
2/13/2023JPMorgan Chase & Co.404,551$24.37M0.0%-24.0%0.836%Search for SEC Filing on Google Icon
2/13/2023Edgewood Management LLC24,060$1.45M0.0%-3.8%0.050%Search for SEC Filing on Google Icon
2/13/2023Teacher Retirement System of Texas9,738$0.59M0.0%-8.8%0.020%Search for SEC Filing on Google Icon
2/10/2023Bank of America Corp DE121,671$7.33M0.0%+46.4%0.251%Search for SEC Filing on Google Icon
2/10/2023American International Group Inc.17,344$1.05M0.0%+3.0%0.036%Search for SEC Filing on Google Icon
2/10/2023Amalgamated Bank6,126$0.37M0.0%+7.1%0.013%Search for SEC Filing on Google Icon
2/10/2023AXQ Capital LP5,125$0.31M0.2%N/A0.011%Search for SEC Filing on Google Icon
2/10/2023Connor Clark & Lunn Investment Management Ltd.60,432$3.64M0.0%+119.3%0.125%Search for SEC Filing on Google Icon
2/10/2023Sectoral Asset Management Inc.115,200$6.94M1.3%N/A0.238%Search for SEC Filing on Google Icon
2/10/2023Victory Capital Management Inc.9,418$0.57M0.0%-35.4%0.018%Search for SEC Filing on Google Icon
2/10/2023Franklin Resources Inc.4,200$0.25M0.0%-33.9%0.009%Search for SEC Filing on Google Icon
2/9/2023First Trust Advisors LP62,396$3.76M0.0%+60.8%0.129%Search for SEC Filing on Google Icon
2/9/2023Jennison Associates LLC49,241$2.97M0.0%N/A0.102%Search for SEC Filing on Google Icon
2/9/2023Victory Capital Management Inc.6,504$0.37M0.0%-55.4%0.013%Search for SEC Filing on Google Icon
2/9/2023Dimensional Fund Advisors LP1,320,501$79.56M0.0%-11.0%2.730%Search for SEC Filing on Google Icon
2/9/2023Principal Financial Group Inc.56,007$3.37M0.0%+194.5%0.116%Search for SEC Filing on Google Icon
2/9/2023Citigroup Inc.63,400$3.82M0.0%-35.4%0.131%Search for SEC Filing on Google Icon
2/8/2023Raymond James & Associates5,005$0.30M0.0%N/A0.010%Search for SEC Filing on Google Icon
2/8/2023UBS Group AG91,069$5.49M0.0%+1,381.0%0.188%Search for SEC Filing on Google Icon
2/8/2023Swiss National Bank79,300$4.78M0.0%+2.7%0.164%Search for SEC Filing on Google Icon
2/8/2023Arizona State Retirement System9,268$0.56M0.0%+4.1%0.019%Search for SEC Filing on Google Icon
2/8/2023Thornburg Investment Management Inc.24,274$1.46M0.0%N/A0.050%Search for SEC Filing on Google Icon
2/7/2023State Board of Administration of Florida Retirement System11,286$0.68M0.0%-29.8%0.023%Search for SEC Filing on Google Icon
2/7/2023Handelsbanken Fonder AB52,000$3.13M0.0%-39.3%0.107%Search for SEC Filing on Google Icon
2/7/2023TD Asset Management Inc81,513$4.91M0.0%+18.9%0.168%Search for SEC Filing on Google Icon
2/6/2023Los Angeles Capital Management LLC5,576$0.34M0.0%-8.7%0.012%Search for SEC Filing on Google Icon
2/3/2023Frazier Life Sciences Management L.P.127,900$7.71M0.5%N/A0.264%Search for SEC Filing on Google Icon
2/3/2023Birchview Capital LP127,195$7.66M5.4%+6.9%0.263%Search for SEC Filing on Google Icon
2/2/2023SG Americas Securities LLC78,772$4.75M0.1%-41.9%0.163%Search for SEC Filing on Google Icon
2/2/2023ProShare Advisors LLC8,719$0.53M0.0%+11.0%0.018%Search for SEC Filing on Google Icon
2/2/2023Monarch Partners Asset Management LLC35,645$2.15M0.6%+6.8%0.074%Search for SEC Filing on Google Icon
2/2/2023HighMark Wealth Management LLC7,527$0.45M0.3%+540.6%0.016%Search for SEC Filing on Google Icon
2/1/2023State of New Jersey Common Pension Fund D37,600$2.27M0.0%N/A0.078%Search for SEC Filing on Google Icon
2/1/2023Zurcher Kantonalbank Zurich Cantonalbank 5,386$0.33M0.0%+28.0%0.011%Search for SEC Filing on Google Icon
2/1/2023Pinnacle Associates Ltd.137,571$8.29M0.2%-1.8%0.284%Search for SEC Filing on Google Icon
1/30/2023New York State Common Retirement Fund35,780$2.16M0.0%-1.7%0.074%Search for SEC Filing on Google Icon
1/26/2023Strs Ohio12,500$0.75M0.0%-36.2%0.026%Search for SEC Filing on Google Icon
1/25/2023Pinnacle Associates Ltd.137,371$8.41M0.2%-1.9%0.284%Search for SEC Filing on Google Icon
1/24/2023Moody Aldrich Partners LLC39,237$2.36M0.5%N/A0.081%Search for SEC Filing on Google Icon
1/23/2023Allspring Global Investments Holdings LLC6,984$0.42M0.0%-45.3%0.014%Search for SEC Filing on Google Icon
12/8/2022Bank of New York Mellon Corp140,192$8.50M0.0%+17.4%0.290%Search for SEC Filing on Google Icon
11/21/2022California State Teachers Retirement System42,203$2.56M0.0%-2.2%0.087%Search for SEC Filing on Google Icon
11/16/2022Balyasny Asset Management LLC6,515$0.40M0.0%-81.0%0.013%Search for SEC Filing on Google Icon
11/16/2022BNP Paribas Arbitrage SNC38,407$2.33M0.0%+362.8%0.079%Search for SEC Filing on Google Icon
11/15/2022State Street Corp1,881,794$114.09M0.0%-16.2%3.890%Search for SEC Filing on Google Icon
11/15/2022Algert Global LLC8,670$0.53M0.0%N/A0.018%Search for SEC Filing on Google Icon
11/15/2022Two Sigma Advisers LP335,000$20.31M0.1%-25.2%0.692%Search for SEC Filing on Google Icon
11/15/2022Two Sigma Investments LP135,685$8.23M0.0%-41.1%0.280%Search for SEC Filing on Google Icon
11/15/2022Vanguard Group Inc.807,960$48.99M0.0%-2.5%1.670%Search for SEC Filing on Google Icon
11/15/2022Perceptive Advisors LLC230,000$13.95M0.4%N/A0.475%Search for SEC Filing on Google Icon
11/15/2022Platinum Investment Management Ltd.48,914$2.97M0.1%-19.2%0.101%Search for SEC Filing on Google Icon
11/15/2022Price T Rowe Associates Inc. MD2,981,941$180.80M0.0%-50.0%6.164%Search for SEC Filing on Google Icon
11/15/2022Putnam Investments LLC14,756$0.89M0.0%+9.4%0.031%Search for SEC Filing on Google Icon
11/15/2022Palo Alto Investors LP1,649,777$100.03M7.9%-1.9%3.410%Search for SEC Filing on Google Icon
11/15/2022Quantamental Technologies LLC5,106$0.31M0.1%N/A0.011%Search for SEC Filing on Google Icon
11/15/2022Marshall Wace LLP107,803$6.54M0.0%-39.6%0.223%Search for SEC Filing on Google Icon
Data available starting January 2016

See Full Table
Prothena logo
Prothena Corp. Plc is a clinical-stage neuroscience company. It focuses on the discovery and development of novel therapies to change the course of devastating diseases. The firm's clinical pipeline includes both wholly-owned and partnered programs being developed for the potential treatment of diseases including AL amyloidosis, ATTR amyloidosis, Alzheimer's disease, Parkinson's disease and other neurodegenerative diseases. The company was founded in December 1969 and is headquartered in Dublin, Ireland.
Read More on Prothena

Today's Range

Now: $48.23
Low: $45.06
High: $48.58

50 Day Range

MA: $52.53
Low: $46.97
High: $58.27

52 Week Range

Now: $48.23
Low: $21.06
High: $66.47

Volume

62,942 shs

Average Volume

490,213 shs

Market Capitalization

$2.53 billion

P/E Ratio

N/A

Dividend Yield

N/A

Beta

0.41

Who are the company insiders with the largest holdings of Prothena?

Prothena's top insider shareholders include:
  1. Ecor1 Capital, Llc (Major Shareholder)
  2. Christopher S Henney (Director)
  3. Wagner M Zago (Insider)
  4. Gene G Kinney (CEO)
  5. Christopher S Henney (Director)
  6. Dennis J Selkoe (Director)
  7. Tran Nguyen (CFO)
  8. Richard T Collier (Director)
  9. Shane Cooke (Director)
  10. Hideki Garren (Insider)
  11. Lars Ekman (Insider)
  12. Michael J Malecek (Insider)
  13. Carol D Karp (Insider)
  14. Dennis J Selkoe (Director)
  15. Karin L Walker (CAO)
  16. Michael J Malecek (Insider)
Learn More about top insider investors at Prothena.

Who are the major institutional investors of Prothena?

Prothena's top institutional shareholders include:
  1. Price T Rowe Associates Inc. MD — 6.63%
  2. Avidity Partners Management LP — 6.10%
  3. First Light Asset Management LLC — 3.17%
  4. Dimensional Fund Advisors LP — 2.73%
  5. T. Rowe Price Investment Management Inc. — 1.92%
  6. Geode Capital Management LLC — 1.48%
Learn More about top institutional investors of Prothena stock.

Which major investors are selling Prothena stock?

During the previous quarter, PRTA stock was sold by these institutional investors:
  1. Dimensional Fund Advisors LP
  2. Renaissance Technologies LLC
  3. JPMorgan Chase & Co.
  4. Simplex Trading LLC
  5. SG Americas Securities LLC
  6. Citigroup Inc.
  7. Handelsbanken Fonder AB
  8. Silverarc Capital Management LLC
Within the previous year, company insiders that have sold Prothena company stock include:
  1. Ecor1 Capital, Llc (Major Shareholder)
  2. Christopher S Henney (Director)
  3. Wagner M Zago (Insider)
  4. Gene G Kinney (CEO)
  5. Christopher S Henney (Director)
  6. Dennis J Selkoe (Director)
  7. Tran Nguyen (CFO)
  8. Richard T Collier (Director)
Learn More investors selling Prothena stock.

Which major investors are buying Prothena stock?

In the last quarter, PRTA stock was acquired by institutional investors including:
  1. Avidity Partners Management LP
  2. Price T Rowe Associates Inc. MD
  3. Point72 Asset Management L.P.
  4. Frazier Life Sciences Management L.P.
  5. Millennium Management LLC
  6. Sectoral Asset Management Inc.
  7. UBS Group AG
  8. T. Rowe Price Investment Management Inc.