| 2/17/2025 | Woodline Partners LP | 451,858 | $0.19M | 0.0% | N/A | 8.983% |  |
| 2/17/2025 | Squarepoint Ops LLC | 337,943 | $0.14M | 0.0% | N/A | 6.719% |  |
| 2/17/2025 | Two Sigma Investments LP | 266,587 | $0.11M | 0.0% | -9.7% | 5.300% |  |
| 2/17/2025 | Two Sigma Advisers LP | 496,500 | $0.21M | 0.0% | -2.3% | 9.871% |  |
| 2/17/2025 | Tang Capital Management LLC | 552,264 | $0.23M | 0.0% | N/A | 10.979% |  |
| 2/17/2025 | Octagon Capital Advisors LP | 11,215,000 | $4.71M | 0.8% | +0.1% | 222.962% |  |
| 2/17/2025 | Millennium Management LLC | 3,033,782 | $1.27M | 0.0% | -7.6% | 60.314% |  |
| 2/17/2025 | Jacobs Levy Equity Management Inc. | 664,423 | $0.28M | 0.0% | N/A | 13.209% |  |
| 2/17/2025 | BNP Paribas Financial Markets | 74,963 | $31K | 0.0% | N/A | 1.490% |  |
| 2/14/2025 | Jane Street Group LLC | 123,159 | $52K | 0.0% | +47.8% | 2.448% |  |
| 2/14/2025 | Northern Trust Corp | 159,685 | $67K | 0.0% | +0.8% | 3.175% |  |
| 2/14/2025 | RBF Capital LLC | 400,000 | $0.17M | 0.0% | -10.9% | 7.952% |  |
| 2/14/2025 | Gilead Sciences Inc. | 16,635,286 | $6.99M | 0.5% | N/A | 330.721% |  |
| 2/13/2025 | Raymond James Financial Inc. | 60,500 | $25K | 0.0% | N/A | 1.203% |  |
| 2/13/2025 | Renaissance Technologies LLC | 379,563 | $0.16M | 0.0% | -51.1% | 7.546% |  |
| 2/7/2025 | BML Capital Management LLC | 184,246 | $77K | 0.0% | -69.4% | 3.663% |  |
| 2/6/2025 | Raymond James Financial Inc. | 60,500 | $25K | 0.0% | N/A | 1.203% |  |
| 11/16/2024 | Geode Capital Management LLC | 585,548 | $0.47M | 0.0% | -9.6% | 0.507% |  |
| 11/15/2024 | Jane Street Group LLC | 83,351 | $67K | 0.0% | -51.8% | 0.072% |  |
| 11/12/2024 | Charles Schwab Investment Management Inc. | 57,055 | $46K | 0.0% | -83.4% | 0.049% |  |
| 9/16/2024 | Cubist Systematic Strategies LLC | 49,816 | $36K | 0.0% | +152.3% | 0.043% |  |
| 9/16/2024 | Point72 Asia Singapore Pte. Ltd. | 76,278 | $55K | 0.0% | N/A | 0.066% |  |
| 8/15/2024 | Point72 Asia Singapore Pte. Ltd. | 76,278 | $55K | 0.0% | N/A | 0.066% |  |
| 8/14/2024 | Cubist Systematic Strategies LLC | 49,816 | $36K | 0.0% | +152.3% | 0.043% |  |
| 8/14/2024 | Marshall Wace LLP | 324,658 | $0.23M | 0.0% | -11.1% | 0.282% |  |
| 8/9/2024 | Renaissance Technologies LLC | 791,200 | $0.57M | 0.0% | -8.2% | 0.688% |  |
| 8/6/2024 | Acadian Asset Management LLC | 1,175,954 | $0.85M | 0.0% | -25.9% | 1.023% |  |
| 5/15/2024 | Price T Rowe Associates Inc. MD | 97,986 | $74K | 0.0% | +127.4% | 0.085% |  |
| 5/10/2024 | Acadian Asset Management LLC | 1,587,451 | $1.20M | 0.0% | +694.6% | 1.381% |  |
| 5/10/2024 | Vanguard Group Inc. | 2,922,454 | $2.21M | 0.0% | -0.5% | 2.543% |  |
| 5/7/2024 | Marquette Asset Management LLC | 178,883 | $0.14M | 0.0% | N/A | 0.156% |  |
| 4/23/2024 | BML Capital Management LLC | 200,464 | $0.15M | 0.1% | N/A | 0.174% |  |
| 3/5/2024 | Twin Focus Capital Partners LLC | 59,359 | $40K | 0.0% | N/A | 0.052% |  |
| 2/14/2024 | Pennant Investors LP | 215,700 | $0.15M | 0.0% | N/A | 0.189% |  |
| 2/14/2024 | Wasatch Advisors LP | 3,784,623 | $2.57M | 0.0% | -40.1% | 3.324% |  |
| 12/1/2023 | Wellington Management Group LLP | 597,434 | $1.28M | 0.0% | +50.4% | 0.524% |  |
| 11/13/2023 | Clear Street Markets LLC | 20,076 | $43K | 0.0% | N/A | 0.018% |  |
| 11/13/2023 | Qtron Investments LLC | 27,528 | $59K | 0.0% | +69.2% | 0.024% |  |
| 11/13/2023 | FMR LLC | 9,682,460 | $20.82M | 0.0% | +1.7% | 8.489% |  |
| 11/8/2023 | Massachusetts Financial Services Co. MA | 830,873 | $1.79M | 0.0% | -17.8% | 0.729% |  |
| 11/8/2023 | Swiss National Bank | 112,300 | $0.24M | 0.0% | -9.2% | 0.099% |  |
| 11/7/2023 | New York State Common Retirement Fund | 34,388 | $74K | 0.0% | +50.6% | 0.030% |  |
| 11/7/2023 | Jump Financial LLC | 36,396 | $78K | 0.0% | N/A | 0.032% |  |
| 11/2/2023 | Regency Capital Management Inc. DE | 30,025 | $65K | 0.1% | -60.0% | 0.026% |  |
| 10/24/2023 | Bank of New York Mellon Corp | 167,731 | $0.36M | 0.0% | +8.6% | 0.147% |  |
| 10/13/2023 | SG Americas Securities LLC | 23,293 | $50K | 0.0% | N/A | 0.020% |  |
| 9/21/2023 | Barclays PLC | 18,551 | $63K | 0.0% | -47.9% | 0.016% |  |
| 8/15/2023 | Caas Capital Management LP | 250,000 | $0.85M | 0.1% | N/A | 0.220% |  |
| 8/14/2023 | Ghisallo Capital Management LLC | 292,316 | $0.99M | 0.1% | N/A | 0.257% |  |
| 8/11/2023 | SVB Financial Group | 25,811 | $88K | 0.2% | -25.0% | 0.023% |  |
| 8/11/2023 | Artal Group S.A. | 6,597,167 | $22.43M | 0.7% | +18.3% | 5.794% |  |
| 8/10/2023 | Monashee Investment Management LLC | 375,000 | $1.28M | 0.3% | N/A | 0.329% |  |
| 8/8/2023 | Wasatch Advisors LP | 6,644,113 | $22.59M | 0.1% | +427.3% | 5.838% |  |
| 8/7/2023 | Principal Financial Group Inc. | 22,817 | $78K | 0.0% | +30.4% | 0.020% |  |
| 8/4/2023 | American International Group Inc. | 1,149,060 | $3.91M | 0.0% | +0.5% | 1.010% |  |
| 8/4/2023 | Maven Securities LTD | 735,559 | $2.50M | 0.0% | N/A | 0.646% |  |
| 7/27/2023 | Virtu Financial LLC | 13,660 | $46K | 0.0% | N/A | 0.012% |  |
| 5/9/2023 | GMT Capital Corp | 3,333,646 | $13.14M | 0.5% | +20.8% | 3.562% |  |
| 4/28/2023 | SG Americas Securities LLC | 16,288 | $64K | 0.0% | +30.8% | 0.017% |  |
| 2/15/2023 | Alkeon Capital Management LLC | 4,605,104 | $23.62M | 0.1% | -6.5% | 4.943% |  |
| 2/13/2023 | The Manufacturers Life Insurance Company | 13,697 | $70K | 0.0% | N/A | 0.015% |  |
| 2/13/2023 | GSA Capital Partners LLP | 69,001 | $0.35M | 0.0% | -11.1% | 0.074% |  |
| 2/13/2023 | Cornercap Investment Counsel Inc. | 39,496 | $0.20M | 0.0% | -12.2% | 0.042% |  |
| 2/10/2023 | HRT Financial LP | 48,028 | $0.25M | 0.0% | N/A | 0.052% |  |
| 2/8/2023 | Swiss National Bank | 112,300 | $0.58M | 0.0% | +2.7% | 0.121% |  |
| 1/30/2023 | New York State Common Retirement Fund | 21,474 | $0.11M | 0.0% | +63.0% | 0.023% |  |
| 11/14/2022 | Tudor Investment Corp Et Al | 25,655 | $0.20M | 0.0% | -31.0% | 0.028% |  |
| 11/14/2022 | PDT Partners LLC | 20,005 | $0.16M | 0.0% | -40.0% | 0.021% |  |
| 11/14/2022 | MetLife Investment Management LLC | 16,710 | $0.13M | 0.0% | N/A | 0.018% |  |
| 11/9/2022 | Massachusetts Financial Services Co. MA | 835,779 | $6.59M | 0.0% | +7.3% | 0.897% |  |
| 11/7/2022 | Nisa Investment Advisors LLC | 5,210 | $37K | 0.0% | +33.2% | 0.006% |  |
| 11/7/2022 | Quantbot Technologies LP | 3,175 | $25K | 0.0% | N/A | 0.003% |  |
| 11/7/2022 | Arizona State Retirement System | 12,619 | $100K | 0.0% | N/A | 0.014% |  |
| 11/7/2022 | ProShare Advisors LLC | 11,252 | $90K | 0.0% | N/A | 0.012% |  |
| 11/3/2022 | Teacher Retirement System of Texas | 14,660 | $0.12M | 0.0% | N/A | 0.016% |  |
| 11/3/2022 | Barclays PLC | 21,177 | $0.17M | 0.0% | -71.9% | 0.023% |  |
| 10/25/2022 | Denali Advisors LLC | 6,500 | $51K | 0.0% | N/A | 0.007% |  |
| 8/16/2022 | Corton Capital Inc. | 10,496 | $41K | 0.0% | N/A | 0.011% |  |
| 8/16/2022 | Delphia USA Inc. | 11,282 | $44K | 0.0% | N/A | 0.012% |  |
| 8/13/2022 | Massachusetts Financial Services Co. MA | 779,168 | $3.04M | 0.0% | -0.7% | 0.837% |  |
| 8/11/2022 | Trexquant Investment LP | 15,172 | $59K | 0.0% | N/A | 0.023% |  |
| 8/11/2022 | Alps Advisors Inc. | 38,808 | $0.15M | 0.0% | -42.2% | 0.059% |  |
| 8/10/2022 | GMT Capital Corp | 1,891,170 | $7.38M | 0.5% | +66.2% | 2.891% |  |
| 8/9/2022 | Swiss National Bank | 77,000 | $0.30M | 0.0% | -9.2% | 0.118% |  |
| 8/3/2022 | Regency Capital Management Inc. DE | 75,000 | $0.29M | 0.3% | N/A | 0.115% |  |
| 7/29/2022 | SG Americas Securities LLC | 12,681 | $49K | 0.0% | N/A | 0.019% |  |
| 7/27/2022 | Bailard Inc. | 21,900 | $85K | 0.0% | N/A | 0.033% |  |
| 6/30/2022 | Amalgamated Bank | 4,817 | $33K | 0.0% | N/A | 0.007% |  |
| 5/17/2022 | RA Capital Management L.P. | 1,440,525 | $9.72M | 0.2% | N/A | 2.202% |  |
| 5/11/2022 | Massachusetts Financial Services Co. MA | 785,020 | $5.30M | 0.0% | +2.8% | 1.201% |  |
| 5/11/2022 | GMT Capital Corp | 1,138,070 | $7.68M | 0.5% | +69.4% | 1.741% |  |
| 5/11/2022 | GSA Capital Partners LLP | 93,166 | $0.63M | 0.1% | -15.0% | 0.143% |  |
| 5/5/2022 | New York State Common Retirement Fund | 13,154 | $89K | 0.0% | -38.1% | 0.020% |  |
| 2/19/2022 | Woodline Partners LP | 1,087,093 | $14.07M | 0.2% | -25.5% | 1.664% |  |
| 2/14/2022 | Virtus ETF Advisers LLC | 11,076 | $0.14M | 0.1% | +18.3% | 0.017% |  |
| 2/14/2022 | Redmile Group LLC | 823,371 | $10.65M | 0.2% | -1.6% | 1.264% |  |
| 2/14/2022 | GSA Capital Partners LLP | 109,607 | $1.42M | 0.2% | N/A | 0.168% |  |
| 2/10/2022 | JPMorgan Chase & Co. | 598,197 | $7.74M | 0.0% | -20.0% | 0.918% |  |
| 2/10/2022 | Rafferty Asset Management LLC | 63,066 | $0.82M | 0.0% | +61.3% | 0.097% |  |
| 2/10/2022 | Massachusetts Financial Services Co. MA | 763,329 | $9.88M | 0.0% | -0.7% | 1.172% |  |