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APLT Insider Trading

Insider Ownership Percentage: 1.60%
Insider Buying (Last 12 Months): $0.00
Insider Selling (Last 12 Months): $18,560.54

Applied Therapeutics Insider Trading History Chart

This chart shows the insider buying and selling history at Applied Therapeutics by year and by quarter.

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Applied Therapeutics Share Price & Price History

Current Price: $0.23
Price Change: ▲ Price Increase of +0.0187 (8.85%)
As of 12/4/2025 05:00 PM ET

This chart shows the closing price history over time for APLT up to the past year.

Skip Chart and Table DataPrice Data in Insider Trading History Table
Days: 30 | 90 | 365

Applied Therapeutics Insider Trading History

Transaction DateInsider NameTitleBuy/SellNumber of SharesAverage Share PriceTotal TransactionShares Held After TransactionDetails
3/4/2025Riccardo PerfettiInsiderSell10,366$0.44$4,561.04890,409View SEC Filing Icon  
2/6/2025Leslie D FuntleyderInsiderSell22,950$0.61$13,999.50404,961View SEC Filing Icon  
8/14/2024Shoshana ShendelmanCEOSell119,591$5.93$709,174.634,690,839View SEC Filing Icon  
8/12/2024Shoshana ShendelmanCEOSell300,000$5.98$1,794,000.005,167,853View SEC Filing Icon  
6/6/2024Leslie D FuntleyderCFOSell16,980$4.32$73,353.60291,441View SEC Filing Icon  
6/6/2024Riccardo PerfettiInsiderSell22,003$4.32$95,052.961,009,534View SEC Filing Icon  
6/6/2024Shoshana ShendelmanCEOSell61,795$4.32$266,954.403,756,019View SEC Filing Icon  
6/4/2024Real Estate Equitie AlexandriaMajor ShareholderSell150,000$4.21$631,500.006,005,077View SEC Filing Icon  
3/14/2024Leslie D FuntleyderCFOSell28,727$5.39$154,838.53308,421View SEC Filing Icon  
3/14/2024Riccardo PerfettiInsiderSell110,804$5.39$597,233.561,031,537View SEC Filing Icon  
3/14/2024Shoshana ShendelmanCEOSell318,573$5.39$1,717,108.473,817,814View SEC Filing Icon  
12/1/2023Stacy J KanterDirectorBuy30,000$2.18$65,400.0063,000View SEC Filing Icon  
11/30/2023Riccardo PerfettiInsiderSell1,583$1.97$3,118.51692,341View SEC Filing Icon  
11/30/2023Shoshana ShendelmanCEOSell3,968$1.97$7,816.962,596,387View SEC Filing Icon  
11/2/2023Real Estate Equitie AlexandriaMajor ShareholderSell103,808$2.32$240,834.565,723,527View SEC Filing Icon  
10/31/2023Real Estate Equitie AlexandriaMajor ShareholderSell155,000$2.41$373,550.006,000,077View SEC Filing Icon  
9/27/2023Riccardo PerfettiInsiderSell10,932$2.70$29,516.40693,924View SEC Filing Icon  
9/27/2023Shoshana ShendelmanCEOSell115,632$2.70$312,206.402,600,355View SEC Filing Icon  
1/11/2023Riccardo PerfettiInsiderSell6,053$0.91$5,508.23154,856View SEC Filing Icon  
1/11/2023Shoshana ShendelmanCEOSell15,870$0.91$14,441.70751,625View SEC Filing Icon  
See Full Table

SEC Filings (Institutional Ownership Changes) for Applied Therapeutics (NASDAQ:APLT)

98.31% of Applied Therapeutics stock is owned by institutions. Institutional ownership can be a sign of analyst confidence in the fundamentals of the stock.

Institutional Buying and Selling by Quarter

This chart shows the instiutional buying and selling at APLT by year and by quarter.

Skip Institutional Buying and Selling Chart and Table DataRead Chart Data in Institutional Trading History Table

Applied Therapeutics Institutional Trading History

Reporting DateHedge FundShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
11/17/2025Vestal Point Capital LP14,250,000$8.62M0.4%+23.9%9.875%Search for SEC Filing on Google Icon
11/17/2025Scientech Research LLC105,110$64K0.0%N/A0.073%Search for SEC Filing on Google Icon
11/17/2025Qube Research & Technologies Ltd1,167,269$0.71M0.0%-36.0%0.809%Search for SEC Filing on Google Icon
11/17/2025Millennium Management LLC1,907,214$1.15M0.0%-1.9%1.322%Search for SEC Filing on Google Icon
11/14/2025Virtu Financial LLC51,017$31K0.0%N/A0.035%Search for SEC Filing on Google Icon
11/14/2025Two Sigma Investments LP198,933$0.12M0.0%-66.5%0.138%Search for SEC Filing on Google Icon
11/14/2025Squarepoint Ops LLC158,865$96K0.0%+1,445.1%0.110%Search for SEC Filing on Google Icon
11/13/2025UBS Group AG1,905,625$1.15M0.0%+129.4%1.323%Search for SEC Filing on Google Icon
11/7/2025Vanguard Group Inc.5,102,689$3.09M0.0%+7.8%3.543%Search for SEC Filing on Google Icon
11/7/2025PNC Financial Services Group Inc.2,901,184$1.76M0.0%N/A2.015%Search for SEC Filing on Google Icon
8/15/2025Birchview Capital LP280,000$87K0.1%N/A0.198%Search for SEC Filing on Google Icon
8/15/2025Adage Capital Partners GP L.L.C.1,211,629$0.38M0.0%-38.2%0.856%Search for SEC Filing on Google Icon
8/14/2025Qube Research & Technologies Ltd1,822,569$0.57M0.0%-6.0%1.287%Search for SEC Filing on Google Icon
8/13/2025Marshall Wace LLP1,544,191$0.48M0.0%+18.1%1.091%Search for SEC Filing on Google Icon
8/12/2025CreativeOne Wealth LLC104,213$32K0.0%+106.7%0.074%Search for SEC Filing on Google Icon
8/8/2025Geode Capital Management LLC968,541$0.30M0.0%-55.0%0.684%Search for SEC Filing on Google Icon
6/27/2025Goldman Sachs Group Inc.316,230$0.16M0.0%-64.9%0.223%Search for SEC Filing on Google Icon
5/16/2025Goldman Sachs Group Inc.316,230$0.16M0.0%-64.9%0.223%Search for SEC Filing on Google Icon
5/16/2025AQR Capital Management LLC572,311$0.28M0.0%N/A0.404%Search for SEC Filing on Google Icon
5/16/2025Alyeska Investment Group L.P.3,107,497$1.52M0.0%+14.8%2.195%Search for SEC Filing on Google Icon
5/15/2025Propel Bio Management LLC11,285,420$5.52M6.4%+17.4%7.971%Search for SEC Filing on Google Icon
5/14/2025CreativeOne Wealth LLC50,413$25K0.0%+132.2%0.036%Search for SEC Filing on Google Icon
5/14/2025T. Rowe Price Investment Management Inc.10,380,590$5.08M0.0%+91.5%7.332%Search for SEC Filing on Google Icon
5/13/2025HighTower Advisors LLC120,001$59K0.0%N/A0.085%Search for SEC Filing on Google Icon
5/12/2025Nuveen LLC281,028$0.14M0.0%N/A0.198%Search for SEC Filing on Google Icon
5/9/2025Charles Schwab Investment Management Inc.632,529$0.31M0.0%-9.7%0.447%Search for SEC Filing on Google Icon
4/29/2025Bank of New York Mellon Corp316,455$0.16M0.0%+23.0%0.224%Search for SEC Filing on Google Icon
3/24/2025Wellington Management Group LLP237,850$0.20M0.0%+17.8%0.204%Search for SEC Filing on Google Icon
3/18/2025California State Teachers Retirement System71,282$61K0.0%+923.3%0.061%Search for SEC Filing on Google Icon
2/27/2025Jefferies Financial Group Inc.276,700$0.24M0.0%N/A0.238%Search for SEC Filing on Google Icon
2/18/2025Knoll Capital Management LLC5,799,687$4.97M3.2%+4.0%4.984%Search for SEC Filing on Google Icon
2/17/2025UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC119,035$0.10M0.0%N/A0.102%Search for SEC Filing on Google Icon
2/17/2025VR Adviser LLC9,990,591$8.55M0.6%+1.7%8.586%Search for SEC Filing on Google Icon
2/17/2025Windsor Advisory Group LLC416,757$0.36M0.4%+109.4%0.358%Search for SEC Filing on Google Icon
2/17/2025Vestal Point Capital LP11,500,000$9.85M0.6%+904.4%9.883%Search for SEC Filing on Google Icon
2/17/2025Two Sigma Investments LP293,810$0.25M0.0%N/A0.253%Search for SEC Filing on Google Icon
2/17/2025Tang Capital Management LLC2,428,169$2.08M0.1%-11.1%2.087%Search for SEC Filing on Google Icon
2/17/2025Toronto Dominion Bank32,000$27K0.0%N/A0.028%Search for SEC Filing on Google Icon
2/17/2025Sphera Funds Management LTD.50,000$43K0.0%-84.0%0.043%Search for SEC Filing on Google Icon
2/17/2025Nuveen Asset Management LLC281,028$0.24M0.0%+7.5%0.242%Search for SEC Filing on Google Icon
2/17/2025Millennium Management LLC1,329,149$1.14M0.0%+252.2%1.142%Search for SEC Filing on Google Icon
2/17/2025Janus Henderson Group PLC35,791$31K0.0%-99.7%0.031%Search for SEC Filing on Google Icon
2/17/2025Jefferies Financial Group Inc.276,700$0.24M0.0%N/A0.238%Search for SEC Filing on Google Icon
2/17/2025Ground Swell Capital LLC31,636$27K0.0%N/A0.027%Search for SEC Filing on Google Icon
2/17/2025Deutsche Bank AG4,468,122$3.84M0.0%+0.7%3.840%Search for SEC Filing on Google Icon
2/17/2025Bank of America Corp DE167,415$0.14M0.0%-46.8%0.144%Search for SEC Filing on Google Icon
2/17/2025BNP Paribas Financial Markets174,651$0.15M0.0%+29.1%0.150%Search for SEC Filing on Google Icon
2/17/2025Alyeska Investment Group L.P.2,707,497$2.32M0.0%+175.8%2.327%Search for SEC Filing on Google Icon
2/14/2025Schonfeld Strategic Advisors LLC8,762,291$7.50M0.0%+2,458.3%7.530%Search for SEC Filing on Google Icon
2/14/2025Tudor Investment Corp ET AL57,454$49K0.0%N/A0.049%Search for SEC Filing on Google Icon
2/14/2025Propel Bio Management LLC9,615,420$8.23M8.2%+46.4%8.264%Search for SEC Filing on Google Icon
2/14/2025Adage Capital Partners GP L.L.C.1,961,629$1.68M0.0%-52.3%1.686%Search for SEC Filing on Google Icon
2/14/2025Price T Rowe Associates Inc. MD34,763$30K0.0%-96.6%0.030%Search for SEC Filing on Google Icon
2/14/2025T. Rowe Price Investment Management Inc.5,420,920$4.64M0.0%+2,511.9%4.659%Search for SEC Filing on Google Icon
2/14/2025Dark Forest Capital Management LP53,718$46K0.0%+54.5%0.046%Search for SEC Filing on Google Icon
2/14/2025Rock Springs Capital Management LP1,917,191$1.64M0.1%+9.8%1.648%Search for SEC Filing on Google Icon
2/13/2025Marshall Wace LLP1,307,381$1.12M0.0%+144.8%1.124%Search for SEC Filing on Google Icon
2/13/2025XTX Topco Ltd173,568$0.15M0.0%+178.0%0.149%Search for SEC Filing on Google Icon
2/13/2025Barclays PLC172,015$0.15M0.0%-14.0%0.148%Search for SEC Filing on Google Icon
2/13/2025Legal & General Group Plc84,018$72K0.0%+293.9%0.072%Search for SEC Filing on Google Icon
2/13/2025Invesco Ltd.53,499$46K0.0%-90.4%0.046%Search for SEC Filing on Google Icon
2/13/2025Aristides Capital LLC156,507$0.13M0.0%N/A0.135%Search for SEC Filing on Google Icon
2/12/2025Franklin Resources Inc.2,003,400$1.72M0.0%-70.5%1.722%Search for SEC Filing on Google Icon
2/12/2025Wellington Management Group LLP237,850$0.20M0.0%+17.8%0.204%Search for SEC Filing on Google Icon
2/12/2025Norges Bank243,200$0.21M0.0%N/A0.209%Search for SEC Filing on Google Icon
2/11/2025Intech Investment Management LLC52,631$45K0.0%+176.1%0.045%Search for SEC Filing on Google Icon
2/10/2025Swiss National Bank146,900$0.13M0.0%N/A0.126%Search for SEC Filing on Google Icon
2/6/2025Charles Schwab Investment Management Inc.700,836$0.60M0.0%-4.7%0.602%Search for SEC Filing on Google Icon
2/3/2025Private Advisor Group LLC40,300$35K0.0%N/A0.035%Search for SEC Filing on Google Icon
1/17/2025SG Americas Securities LLC40,747$35K0.0%+169.0%0.035%Search for SEC Filing on Google Icon
1/15/2025Hennion & Walsh Asset Management Inc.313,355$0.27M0.0%+18.1%0.269%Search for SEC Filing on Google Icon
11/27/2024Franklin Resources Inc.6,800,910$60.46M0.0%-33.4%5.845%Search for SEC Filing on Google Icon
11/19/2024Barclays PLC200,012$1.70M0.0%+186.1%0.172%Search for SEC Filing on Google Icon
11/16/2024Geode Capital Management LLC2,091,669$17.78M0.0%-0.3%1.798%Search for SEC Filing on Google Icon
11/15/2024Barclays PLC200,012$1.70M0.0%+186.1%0.172%Search for SEC Filing on Google Icon
11/15/2024Y Intercept Hong Kong Ltd17,542$0.15M0.0%N/A0.015%Search for SEC Filing on Google Icon
11/15/2024XTX Topco Ltd62,440$0.53M0.0%N/A0.054%Search for SEC Filing on Google Icon
11/15/2024Wellington Management Group LLP201,966$1.72M0.0%N/A0.174%Search for SEC Filing on Google Icon
11/15/2024Sphera Funds Management LTD.311,572$2.65M0.4%-53.8%0.268%Search for SEC Filing on Google Icon
11/15/2024State Street Corp3,694,607$31.40M0.0%+123.1%3.175%Search for SEC Filing on Google Icon
11/15/2024Parkman Healthcare Partners LLC907,294$7.71M1.0%-21.0%0.780%Search for SEC Filing on Google Icon
11/15/2024Janus Henderson Group PLC10,541,528$89.66M0.0%+37.8%9.059%Search for SEC Filing on Google Icon
11/14/2024Vestal Point Capital LP1,145,000$9.73M0.7%-78.9%0.984%Search for SEC Filing on Google Icon
11/14/2024Walleye Capital LLC137,593$1.17M0.0%-65.8%0.118%Search for SEC Filing on Google Icon
11/14/2024Ally Bridge Group NY LLC618,332$5.26M2.8%N/A0.531%Search for SEC Filing on Google Icon
11/14/2024MetLife Investment Management LLC56,302$0.48M0.0%+129.1%0.048%Search for SEC Filing on Google Icon
11/13/2024BNP Paribas Financial Markets135,272$1.15M0.0%+1,855.1%0.116%Search for SEC Filing on Google Icon
11/13/2024The Manufacturers Life Insurance Company123,725$1.05M0.0%+236.0%0.106%Search for SEC Filing on Google Icon
11/12/2024Charles Schwab Investment Management Inc.735,217$6.25M0.0%+165.2%0.640%Search for SEC Filing on Google Icon
11/9/2024Intech Investment Management LLC19,064$0.16M0.0%N/A0.017%Search for SEC Filing on Google Icon
10/23/2024Hennion & Walsh Asset Management Inc.265,372$2.26M0.1%+34.7%0.232%Search for SEC Filing on Google Icon
10/3/2024SG Americas Securities LLC15,146$0.13M0.0%-18.4%0.013%Search for SEC Filing on Google Icon
8/27/2024Logos Global Management LP600,000$2.66M0.2%-55.6%0.525%Search for SEC Filing on Google Icon
8/16/2024Perceptive Advisors LLC8,005,000$37.38M0.9%-5.9%7.006%Search for SEC Filing on Google Icon
8/16/2024Algert Global LLC23,476$0.11M0.0%N/A0.021%Search for SEC Filing on Google Icon
8/16/2024Frazier Life Sciences Management L.P.2,286,135$10.68M0.5%+17.1%2.001%Search for SEC Filing on Google Icon
8/15/2024The Manufacturers Life Insurance Company36,824$0.17M0.0%N/A0.032%Search for SEC Filing on Google Icon
8/14/2024Logos Global Management LP600,000$2.66M0.2%-55.6%0.525%Search for SEC Filing on Google Icon
8/13/2024Sei Investments Co.114,619$0.54M0.0%N/A0.100%Search for SEC Filing on Google Icon
8/12/2024Marathon Trading Investment Management LLC15,907$74K0.0%-73.0%0.014%Search for SEC Filing on Google Icon
Data available starting January 2016

See Full Table
Applied Therapeutics logo
Applied Therapeutics, Inc., a clinical-stage biopharmaceutical company, engages in the development of a pipeline of novel product candidates against validated molecular targets in indications of high unmet medical need in the United States. The company's lead product candidate is AT-007 (also called govorestat) that has completed phase 3 for the treatment of galactosemia in healthy volunteers and adults, in pediatric clinical study for the treatment of galactosemia in kids, for treating enzyme sorbitol dehydrogenase, and for the treatment of phosphomannomutase enzyme-CDG. It also develops AT-001 (also called caficrestat) that is in phase 3 clinical trials to treat diabetic cardiomyopathy, as well as for the treatment of diabetic peripheral neuropathy; and AT-003, which is in preclinical studies for the treatment diabetic retinopathy. The company has exclusive license and supply agreement with Mercury Pharma Group Limited to commercialize drug products containing AT-007. Applied Therapeutics, Inc. was incorporated in 2016 and is headquartered in New York, New York.
Read More on Applied Therapeutics

Today's Range

Now: $0.23
Low: $0.21
High: $0.24

50 Day Range

MA: $0.82
Low: $0.21
High: $1.47

52 Week Range

Now: $0.23
Low: $0.20
High: $1.50

Volume

8,521,314 shs

Average Volume

26,074,836 shs

Market Capitalization

$33.17 million

P/E Ratio

N/A

Dividend Yield

N/A

Beta

1.99

Who are the company insiders with the largest holdings of Applied Therapeutics?

Applied Therapeutics' top insider shareholders include:
  1. Real Estate Equitie Alexandria (Major Shareholder)
  2. Shoshana Shendelman (CEO)
  3. Riccardo Perfetti (Insider)
  4. Leslie D Funtleyder (Insider)
  5. Leslie D Funtleyder (CFO)
Learn More about top insider investors at Applied Therapeutics.

Who are the major institutional investors of Applied Therapeutics?

Applied Therapeutics' top institutional investors include:
  1. Vestal Point Capital LP — 9.88%
  2. Vanguard Group Inc. — 3.54%
  3. PNC Financial Services Group Inc. — 2.01%
  4. Millennium Management LLC — 1.32%
  5. UBS Group AG — 1.32%
  6. Qube Research & Technologies Ltd — 0.81%
Learn More about top institutional investors of Applied Therapeutics stock.

Which major investors are selling Applied Therapeutics stock?

In the previous quarter, APLT stock was sold by these institutional investors:
  1. Qube Research & Technologies Ltd
  2. Two Sigma Investments LP
  3. Millennium Management LLC
Within the previous year, company insiders that have sold Applied Therapeutics company stock include:
  1. Real Estate Equitie Alexandria (Major Shareholder)
  2. Shoshana Shendelman (CEO)
Learn More investors selling Applied Therapeutics stock.

Which major investors are buying Applied Therapeutics stock?

In the previous quarter, APLT stock was acquired by institutional investors including:
  1. PNC Financial Services Group Inc.
  2. Vestal Point Capital LP
  3. UBS Group AG
  4. Vanguard Group Inc.
  5. Squarepoint Ops LLC
  6. Scientech Research LLC
  7. Susquehanna International Group LLP
  8. Virtu Financial LLC