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AXSM Insider Trading

Insider Ownership Percentage: 22.30%
Insider Buying (Last 12 Months): $200,466.00
Insider Selling (Last 12 Months): $121,620,175.72

Axsome Therapeutics Insider Trading History Chart

This chart shows the insider buying and selling history at Axsome Therapeutics by year and by quarter.

Skip ChartChart Data in Insider Trading History Table

Axsome Therapeutics Share Price & Price History

Current Price: $156.92
Price Change: ▼ Price Decrease of -1.96 (-1.23%)
As of 03/20/2026 05:00 PM ET

This chart shows the closing price history over time for AXSM up to the past year.

Skip Chart and Table DataPrice Data in Insider Trading History Table
Days: 30 | 90 | 365

Axsome Therapeutics Insider Trading History

Transaction DateInsider NameTitleBuy/SellNumber of SharesAverage Share PriceTotal TransactionShares Held After TransactionDetails
2/26/2026Mark ColemanDirectorSell25,000$161.11$4,027,750.0047,140View SEC Filing Icon  
2/26/2026Mark L. JacobsonCOOSell35,378$161.88$5,726,990.64View SEC Filing Icon  
2/2/2026Herriot TabuteauCEOSell32,410$185.60$6,015,296.007,229View SEC Filing Icon  
1/22/2026Nick PizzieCFOSell12,000$187.92$2,255,040.0042,588View SEC Filing Icon  
1/21/2026Ari MaizelInsiderSell7,500$184.44$1,383,300.00View SEC Filing Icon  
1/7/2026Herriot TabuteauCEOSell31,261$170.38$5,326,249.187,229View SEC Filing Icon  
1/6/2026Herriot TabuteauCEOSell29,450$172.33$5,075,118.507,229View SEC Filing Icon  
1/5/2026Herriot TabuteauCEOSell78,703$171.28$13,480,249.847,229View SEC Filing Icon  
12/31/2025Mark E. SaadDirectorSell37,577$165.18$6,206,968.8610,002View SEC Filing Icon  
12/4/2025Herriot TabuteauCEOSell10,558$148.18$1,564,484.447,229View SEC Filing Icon  
12/3/2025Herriot TabuteauCEOSell20,163$146.94$2,962,751.227,229View SEC Filing Icon  
12/2/2025Herriot TabuteauCEOSell49,252$144.59$7,121,346.687,229View SEC Filing Icon  
11/5/2025Herriot TabuteauCEOSell21,775$134.49$2,928,519.757,229View SEC Filing Icon  
11/4/2025Herriot TabuteauCEOSell50,459$133.79$6,750,909.617,229View SEC Filing Icon  
11/3/2025Herriot TabuteauCEOSell91,705$132.34$12,136,239.707,229View SEC Filing Icon  
10/8/2025Herriot TabuteauCEOSell12,774$118.84$1,518,062.167,229View SEC Filing Icon  
10/7/2025Herriot TabuteauCEOSell13,390$118.77$1,590,330.307,229View SEC Filing Icon  
10/6/2025Herriot TabuteauCEOSell19,220$120.17$2,309,667.407,229View SEC Filing Icon  
9/22/2025Mark L. JacobsonCOOSell10,000$115.96$1,159,600.00View SEC Filing Icon  
9/16/2025Herriot TabuteauCEOSell19,719$114.19$2,251,712.617,229View SEC Filing Icon  
9/16/2025Mark L. JacobsonCOOSell45,783$114.48$5,241,237.84View SEC Filing Icon  
9/15/2025Herriot TabuteauCEOSell15,254$117.37$1,790,361.987,229View SEC Filing Icon  
9/12/2025Herriot TabuteauCEOSell27,907$118.96$3,319,816.727,229View SEC Filing Icon  
9/8/2025Mark ColemanDirectorBuy1,575$127.28$200,466.0048,212View SEC Filing Icon  
9/5/2025Mark E. SaadDirectorSell9,127$125.07$1,141,513.8910,002View SEC Filing Icon  
9/2/2025Roger JeffsDirectorSell13,464$123.68$1,665,227.5257,510View SEC Filing Icon  
8/28/2025Roger JeffsDirectorSell20,000$121.60$2,432,000.0090,974View SEC Filing Icon  
8/26/2025Roger JeffsDirectorSell20,000$120.03$2,400,600.00110,974View SEC Filing Icon  
8/22/2025Roger JeffsDirectorSell16,694$120.08$2,004,615.52150,974View SEC Filing Icon  
6/23/2025Hunter R. MurdockGeneral CounselSell6,014$100.12$602,121.68View SEC Filing Icon  
6/20/2025Hunter R. MurdockGeneral CounselSell7,500$102.47$768,525.00View SEC Filing Icon  
6/17/2025Hunter R. MurdockGeneral CounselSell7,500$100.26$751,950.00View SEC Filing Icon  
6/9/2025Mark L. JacobsonCOOSell25,000$110.44$2,761,000.005,783View SEC Filing Icon  
5/28/2025Mark L. JacobsonCOOSell20,000$103.45$2,069,000.005,783View SEC Filing Icon  
5/27/2025Mark ColemanDirectorSell3,750$105.47$395,512.5050,387View SEC Filing Icon  
5/27/2025Mark L. JacobsonCOOSell20,673$104.66$2,163,636.185,783View SEC Filing Icon  
5/20/2025Mark ColemanDirectorSell3,000$107.49$322,470.0054,137View SEC Filing Icon  
2/14/2025Nick PizzieCFOSell3,000$131.07$393,210.0042,187View SEC Filing Icon  
9/11/2024Mark E. SaadDirectorSell11,016$91.31$1,005,870.9610,002View SEC Filing Icon  
8/9/2024Mark L. JacobsonCOOSell47,739$84.26$4,022,488.145,783View SEC Filing Icon  
5/29/2024Mark L. JacobsonCOOSell7,910$74.31$587,792.105,783View SEC Filing Icon  
5/28/2024Mark ColemanDirectorSell5,249$75.21$394,777.2919,848View SEC Filing Icon  
4/1/2024Mark L. JacobsonCOOSell24,662$77.24$1,904,892.88View SEC Filing Icon  
3/14/2024Roger JeffsDirectorSell29,976$69.70$2,089,327.20120,756View SEC Filing Icon  
9/15/2023Mark ColemanDirectorSell11,016$75.19$828,293.0425,097View SEC Filing Icon  
See Full Table

SEC Filings (Institutional Ownership Changes) for Axsome Therapeutics (NASDAQ:AXSM)

81.49% of Axsome Therapeutics stock is owned by institutions. Institutional ownership can be a sign of analyst confidence in the fundamentals of the stock.

Institutional Buying and Selling by Quarter

This chart shows the instiutional buying and selling at AXSM by year and by quarter.

Skip Institutional Buying and Selling Chart and Table DataRead Chart Data in Institutional Trading History Table

Axsome Therapeutics Institutional Trading History

Reporting DateHedge FundShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
3/17/2026Rockefeller Capital Management L.P.7,453$1.36M0.0%+29.9%0.015%Search for SEC Filing on Google Icon
3/4/2026SHP Wealth Management940$0.17M0.0%N/A0.002%Search for SEC Filing on Google Icon
3/3/2026Caitong International Asset Management Co. Ltd415$76K0.0%N/A0.001%Search for SEC Filing on Google Icon
2/26/2026Seven Fleet Capital Management LP12,955$2.37M1.8%N/A0.025%Search for SEC Filing on Google Icon
2/23/2026Virtu Financial LLC15,573$2.84M0.1%N/A0.031%Search for SEC Filing on Google Icon
2/19/2026T. Rowe Price Investment Management Inc.13,645$2.49M0.0%-95.0%0.027%Search for SEC Filing on Google Icon
2/19/2026Invesco Ltd.1,273,494$232.59M0.0%+28.6%2.526%Search for SEC Filing on Google Icon
2/18/2026Strive Financial Group LLC337$62K0.0%N/A0.001%Search for SEC Filing on Google Icon
2/18/2026Ameriflex Group Inc.200$37K0.0%N/A0.000%Search for SEC Filing on Google Icon
2/18/2026Mercer Global Advisors Inc. ADV3,222$0.59M0.0%+64.2%0.006%Search for SEC Filing on Google Icon
2/18/2026Vident Advisory LLC1,677$0.31M0.0%-14.3%0.003%Search for SEC Filing on Google Icon
2/18/2026Empowered Funds LLC1,302$0.24M0.0%N/A0.003%Search for SEC Filing on Google Icon
2/18/2026KVP Capital Advisors LP36,200$6.61M6.4%N/A0.072%Search for SEC Filing on Google Icon
2/18/2026XTX Topco Ltd31,854$5.82M0.2%+1,632.1%0.063%Search for SEC Filing on Google Icon
2/18/2026Vestal Point Capital LP210,000$38.35M1.3%+40.0%0.417%Search for SEC Filing on Google Icon
2/18/2026Virtus Investment Advisers LLC4,611$0.84M0.2%+10.2%0.009%Search for SEC Filing on Google Icon
2/18/2026Wellington Management Group LLP1,221,656$223.12M0.1%-8.5%2.423%Search for SEC Filing on Google Icon
2/18/2026Superstring Capital Management LP37,433$6.84M3.7%N/A0.074%Search for SEC Filing on Google Icon
2/18/2026RTW Investments LP888,001$162.19M1.6%-20.6%1.761%Search for SEC Filing on Google Icon
2/18/2026Orbimed Advisors LLC253,121$46.23M1.0%-52.4%0.502%Search for SEC Filing on Google Icon
2/18/2026Odyssean LLC4,983$0.91M0.7%N/A0.010%Search for SEC Filing on Google Icon
2/18/2026Millennium Management LLC33,937$6.20M0.0%+491.1%0.067%Search for SEC Filing on Google Icon
2/18/2026Man Group plc228,641$41.76M0.1%-20.6%0.454%Search for SEC Filing on Google Icon
2/18/2026Engineers Gate Manager LP26,055$4.76M0.1%+114.0%0.052%Search for SEC Filing on Google Icon
2/18/2026Cormorant Asset Management LP75,000$13.70M0.6%-25.0%0.149%Search for SEC Filing on Google Icon
2/18/2026BVF Inc. IL45,757$8.36M0.3%-90.6%0.091%Search for SEC Filing on Google Icon
2/18/20269823 Capital L.P.1,215$0.22M0.2%N/A0.002%Search for SEC Filing on Google Icon
2/17/2026Guggenheim Capital LLC13,030$2.38M0.0%+4.1%0.026%Search for SEC Filing on Google Icon
2/17/2026PDT Partners LLC3,577$0.65M0.0%N/A0.007%Search for SEC Filing on Google Icon
2/17/2026AQR Capital Management LLC103,418$18.89M0.0%-12.8%0.205%Search for SEC Filing on Google Icon
2/17/2026Abel Hall LLC1,169$0.21M0.0%N/A0.002%Search for SEC Filing on Google Icon
2/17/2026Lazard Asset Management LLC13,410$2.45M0.0%-38.6%0.027%Search for SEC Filing on Google Icon
2/17/2026Trexquant Investment LP49,136$8.97M0.1%+416.1%0.097%Search for SEC Filing on Google Icon
2/17/2026Price T Rowe Associates Inc. MD1,509,870$275.76M0.0%+45.5%2.995%Search for SEC Filing on Google Icon
2/17/2026T. Rowe Price Investment Management Inc.13,645$2.49M0.0%-95.0%0.027%Search for SEC Filing on Google Icon
2/17/2026Quantitative Investment Management LLC2,524$0.46M0.0%+20.5%0.005%Search for SEC Filing on Google Icon
2/17/2026Osaic Holdings Inc.17,642$3.22M0.0%+175.5%0.035%Search for SEC Filing on Google Icon
2/17/2026Adage Capital Partners GP L.L.C.367,578$67.13M0.1%-17.4%0.729%Search for SEC Filing on Google Icon
2/17/2026California State Teachers Retirement System33,667$6.15M0.0%-1.9%0.067%Search for SEC Filing on Google Icon
2/17/2026Russell Investments Group Ltd.35,575$6.50M0.0%+39.0%0.071%Search for SEC Filing on Google Icon
2/17/2026Kemnay Advisory Services Inc.167$31K0.0%N/A0.000%Search for SEC Filing on Google Icon
2/17/2026State of Wisconsin Investment Board26,603$4.86M0.0%-12.3%0.053%Search for SEC Filing on Google Icon
2/17/2026Captrust Financial Advisors11,244$2.05M0.0%+41.3%0.022%Search for SEC Filing on Google Icon
2/17/2026&PARTNERS1,602$0.29M0.0%N/A0.003%Search for SEC Filing on Google Icon
2/17/2026Royal Bank of Canada12,074$2.21M0.0%+9.2%0.024%Search for SEC Filing on Google Icon
2/17/2026Blair William & Co. IL46,840$8.56M0.0%-6.5%0.093%Search for SEC Filing on Google Icon
2/17/2026Graham Capital Management L.P.1,532$0.28M0.0%-41.2%0.003%Search for SEC Filing on Google Icon
2/17/2026Cynosure Group LLC3,475$0.64M0.0%-55.7%0.007%Search for SEC Filing on Google Icon
2/16/2026Occam Crest Management LP35,000$6.39M4.4%+6.1%0.069%Search for SEC Filing on Google Icon
2/16/2026Sofinnova Investments Inc.12,266$2.24M0.1%-96.9%0.024%Search for SEC Filing on Google Icon
2/16/2026TritonPoint Partners LLC1,147$0.21M0.1%N/A0.002%Search for SEC Filing on Google Icon
2/16/2026Vanguard Personalized Indexing Management LLC2,190$0.40M0.0%+4.2%0.004%Search for SEC Filing on Google Icon
2/16/2026Verition Fund Management LLC3,409$0.62M0.0%+71.4%0.007%Search for SEC Filing on Google Icon
2/16/2026MML Investors Services LLC2,388$0.44M0.0%N/A0.005%Search for SEC Filing on Google Icon
2/16/2026Mariner LLC15,288$2.80M0.0%-8.0%0.030%Search for SEC Filing on Google Icon
2/16/2026Nicholas Investment Partners LP91,564$16.72M1.2%+88.2%0.182%Search for SEC Filing on Google Icon
2/16/2026First Turn Management LLC206,921$37.79M4.3%+35.6%0.410%Search for SEC Filing on Google Icon
2/16/2026Kennedy Capital Management LLC39,134$7.15M0.2%+0.9%0.078%Search for SEC Filing on Google Icon
2/16/2026Landscape Capital Management L.L.C.15,305$2.80M0.2%-20.7%0.030%Search for SEC Filing on Google Icon
2/16/2026Eventide Asset Management LLC571,226$104.20M1.6%-23.5%1.133%Search for SEC Filing on Google Icon
2/16/2026Entropy Technologies LP8,192$1.50M0.1%N/A0.016%Search for SEC Filing on Google Icon
2/16/2026Arax Advisory Partners194$35K0.0%-92.8%0.000%Search for SEC Filing on Google Icon
2/16/2026Barclays PLC76,853$14.04M0.0%+6.6%0.152%Search for SEC Filing on Google Icon
2/13/2026FORA Capital LLC5,714$1.04M0.1%N/A0.011%Search for SEC Filing on Google Icon
2/13/2026Marshall Wace LLP320,568$58.55M0.1%-15.2%0.636%Search for SEC Filing on Google Icon
2/13/2026The Manufacturers Life Insurance Company 133,884$23.66M0.0%+0.9%0.266%Search for SEC Filing on Google Icon
2/13/2026CANADA LIFE ASSURANCE Co4,007$0.73M0.0%-55.4%0.008%Search for SEC Filing on Google Icon
2/13/2026Bridgewater Associates LP47,444$8.67M0.0%N/A0.094%Search for SEC Filing on Google Icon
2/13/2026Stifel Financial Corp5,868$1.07M0.0%+6.6%0.012%Search for SEC Filing on Google Icon
2/13/2026Smartleaf Asset Management LLC374$68K0.0%+87.9%0.001%Search for SEC Filing on Google Icon
2/13/2026Morgan Stanley491,201$89.71M0.0%+19.9%0.974%Search for SEC Filing on Google Icon
2/13/2026Essex Investment Management Co. LLC17,381$3.17M0.5%+5,383.0%0.034%Search for SEC Filing on Google Icon
2/13/2026Rafferty Asset Management LLC1,567$0.29M0.0%-10.0%0.003%Search for SEC Filing on Google Icon
2/13/2026First Trust Advisors LP43,413$7.93M0.0%+16.9%0.086%Search for SEC Filing on Google Icon
2/13/2026Headlands Technologies LLC5,187$0.95M0.1%+101.5%0.010%Search for SEC Filing on Google Icon
2/13/2026Birchview Capital LP6,061$1.11M0.6%+1.0%0.012%Search for SEC Filing on Google Icon
2/13/2026Charles Schwab Investment Management Inc.402,700$73.55M0.0%+5.4%0.799%Search for SEC Filing on Google Icon
2/13/2026Police & Firemen s Retirement System of New Jersey10,982$2.01M0.0%-2.0%0.022%Search for SEC Filing on Google Icon
2/13/2026State Street Corp958,150$175M0.0%+1.6%1.901%Search for SEC Filing on Google Icon
2/13/2026Van ECK Associates Corp35,077$6.41M0.0%+135.8%0.070%Search for SEC Filing on Google Icon
2/13/2026Ieq Capital LLC9,395$1.72M0.0%-13.2%0.019%Search for SEC Filing on Google Icon
2/13/2026Martingale Asset Management L P7,406$1.35M0.0%+94.9%0.015%Search for SEC Filing on Google Icon
2/13/2026Caitong International Asset Management Co. Ltd1,223$0.22M0.6%N/A0.002%Search for SEC Filing on Google Icon
2/13/2026UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC87,249$15.94M0.0%+0.6%0.173%Search for SEC Filing on Google Icon
2/13/2026Wells Fargo & Company MN89,661$16.38M0.0%+62.2%0.178%Search for SEC Filing on Google Icon
2/13/2026Y Intercept Hong Kong Ltd34,854$6.37M0.1%+29.0%0.069%Search for SEC Filing on Google Icon
2/13/2026Rhenman & Partners Asset Management AB114,800$20.97M2.0%-33.6%0.228%Search for SEC Filing on Google Icon
2/13/2026Summit Financial LLC70,628$12.90M0.2%-8.9%0.140%Search for SEC Filing on Google Icon
2/13/2026Howland Capital Management LLC2,220$0.41M0.0%N/A0.004%Search for SEC Filing on Google Icon
2/13/2026Castleark Management LLC24,253$4.43M0.1%+60.2%0.048%Search for SEC Filing on Google Icon
2/12/2026HRT Financial LP18,862$3.44M0.0%+726.9%0.037%Search for SEC Filing on Google Icon
2/12/2026Orion Porfolio Solutions LLC1,683$0.31M0.0%-23.1%0.003%Search for SEC Filing on Google Icon
2/12/2026MetLife Investment Management LLC164,871$30.11M0.1%-16.4%0.327%Search for SEC Filing on Google Icon
2/12/2026Cibc World Markets Corp2,715$0.50M0.0%N/A0.005%Search for SEC Filing on Google Icon
2/12/2026Commonwealth Equity Services LLC1,522$0.28M0.0%N/A0.003%Search for SEC Filing on Google Icon
2/12/2026Tocqueville Asset Management L.P.4,400$0.80M0.0%-22.1%0.009%Search for SEC Filing on Google Icon
2/12/2026Renaissance Technologies LLC170,000$31.05M0.0%+13.3%0.337%Search for SEC Filing on Google Icon
2/12/2026Dimensional Fund Advisors LP12,431$2.27M0.0%-35.2%0.025%Search for SEC Filing on Google Icon
2/12/2026Federated Hermes Inc.87,280$15.94M0.0%+52.4%0.173%Search for SEC Filing on Google Icon
2/12/2026Ensign Peak Advisors Inc18,845$3.44M0.0%-22.6%0.037%Search for SEC Filing on Google Icon
Data available starting January 2016

See Full Table
Axsome Therapeutics logo
Axsome Therapeutics, Inc., a biopharmaceutical company, engages in the development of novel therapies for central nervous system (CNS) disorders in the United States. The company's commercial product portfolio includes Auvelity (dextromethorphan-bupropion), a N-methyl-D-aspartate receptor antagonist with multimodal activity indicated for the treatment of major depressive disorder; and Sunosi (solriamfetol), a medication indicated to the treatment of excessive daytime sleepiness in patients with narcolepsy or obstructive sleep apnea. It is also developing AXS-05, which is in Phase III clinical trial to treat Alzheimer's disease agitation, as well as that has completed phase II clinical trial for the treatment of smoking cessation; AXS-07, an investigational medicine that has completed Phase III trials for the acute treatment of migraine; AXS-12, an investigational medicine, which is in Phase III trial to treat narcolepsy; AXS-14, a selective and potent norepinephrine reuptake inhibitor that has completed Phase III trial for the treatment of fibromyalgia and other conditions; and solriamfetol, a dual-acting dopamine and norepinephrine reuptake inhibitor, which has completed a Phase 2 trial for treating attention-deficit/hyperactivity disorder, and is in phase 2 major depressive, binge eating, and shift work disorder. Axsome Therapeutics, Inc. has a research collaboration agreement with Duke University for evaluating AXS-05 in smoking cessation. The company was incorporated in 2012 and is based in New York, New York.
Read More on Axsome Therapeutics

Today's Range

Now: $156.92
Low: $155.42
High: $160.03

50 Day Range

MA: $174.76
Low: $154.12
High: $189.10

52 Week Range

Now: $156.92
Low: $86.99
High: $191.50

Volume

849,314 shs

Average Volume

627,105 shs

Market Capitalization

$8.03 billion

P/E Ratio

N/A

Dividend Yield

N/A

Beta

0.43

Who are the company insiders with the largest holdings of Axsome Therapeutics?

Axsome Therapeutics' top insider investors include:
  1. Roger Jeffs (Director)
  2. Mark Coleman (Director)
  3. Nick Pizzie (CFO)
  4. Mark E Saad (Director)
  5. Herriot Tabuteau (CEO)
  6. Mark L Jacobson (COO)
  7. Ari Maizel (Insider)
  8. Hunter R Murdock (General Counsel)
  9. Mark L Jacobson (COO)
Learn More about top insider investors at Axsome Therapeutics.

Who are the major institutional investors of Axsome Therapeutics?

Axsome Therapeutics' top institutional shareholders include:
  1. Vanguard Group Inc. — 8.26%
  2. Price T Rowe Associates Inc. MD — 3.00%
  3. Invesco Ltd. — 2.53%
  4. Wellington Management Group LLP — 2.42%
  5. Geode Capital Management LLC — 2.00%
  6. State Street Corp — 1.90%
Learn More about top institutional investors of Axsome Therapeutics stock.

Which institutional investors are selling Axsome Therapeutics stock?

During the last quarter, AXSM stock was sold by these institutional investors:
  1. BVF Inc. IL
  2. Sofinnova Investments Inc.
  3. Orbimed Advisors LLC
  4. T. Rowe Price Investment Management Inc.
  5. T. Rowe Price Investment Management Inc.
  6. RTW Investments LP
  7. Eventide Asset Management LLC
  8. Wellington Management Group LLP
During the last year, company insiders that have sold Axsome Therapeutics company stock include:
  1. Roger Jeffs (Director)
  2. Mark Coleman (Director)
  3. Nick Pizzie (CFO)
  4. Mark E Saad (Director)
  5. Herriot Tabuteau (CEO)
  6. Mark L Jacobson (COO)
  7. Ari Maizel (Insider)
  8. Hunter R Murdock (General Counsel)
Learn More investors selling Axsome Therapeutics stock.

Which institutional investors are buying Axsome Therapeutics stock?

Within the previous quarter, AXSM stock was bought by institutional investors including:
  1. Norges Bank
  2. Price T Rowe Associates Inc. MD
  3. Invesco Ltd.
  4. Assenagon Asset Management S.A.
  5. UBS Group AG
  6. BNP Paribas Financial Markets
  7. M&G PLC
  8. Morgan Stanley