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AXSM Insider Trading

Insider Ownership Percentage: 22.30%
Insider Buying (Last 12 Months): $200,466.00
Insider Selling (Last 12 Months): $72,516,422.70

Axsome Therapeutics Insider Trading History Chart

This chart shows the insider buying and selling history at Axsome Therapeutics by year and by quarter.

Skip ChartChart Data in Insider Trading History Table

Axsome Therapeutics Share Price & Price History

Current Price: $148.04
Price Change: ▲ Price Increase of +0.23 (0.16%)
As of 12/4/2025 05:00 PM ET

This chart shows the closing price history over time for AXSM up to the past year.

Skip Chart and Table DataPrice Data in Insider Trading History Table
Days: 30 | 90 | 365

Axsome Therapeutics Insider Trading History

Transaction DateInsider NameTitleBuy/SellNumber of SharesAverage Share PriceTotal TransactionShares Held After TransactionDetails
11/5/2025Herriot TabuteauCEOSell21,775$134.49$2,928,519.757,229View SEC Filing Icon  
11/4/2025Herriot TabuteauCEOSell50,459$133.79$6,750,909.617,229View SEC Filing Icon  
11/3/2025Herriot TabuteauCEOSell91,705$132.34$12,136,239.707,229View SEC Filing Icon  
10/8/2025Herriot TabuteauCEOSell12,774$118.84$1,518,062.167,229View SEC Filing Icon  
10/7/2025Herriot TabuteauCEOSell13,390$118.77$1,590,330.307,229View SEC Filing Icon  
10/6/2025Herriot TabuteauCEOSell19,220$120.17$2,309,667.407,229View SEC Filing Icon  
9/22/2025Mark L. JacobsonCOOSell10,000$115.96$1,159,600.00View SEC Filing Icon  
9/16/2025Herriot TabuteauCEOSell19,719$114.19$2,251,712.617,229View SEC Filing Icon  
9/16/2025Mark L. JacobsonCOOSell45,783$114.48$5,241,237.84View SEC Filing Icon  
9/15/2025Herriot TabuteauCEOSell15,254$117.37$1,790,361.987,229View SEC Filing Icon  
9/12/2025Herriot TabuteauCEOSell27,907$118.96$3,319,816.727,229View SEC Filing Icon  
9/8/2025Mark ColemanDirectorBuy1,575$127.28$200,466.0048,212View SEC Filing Icon  
9/5/2025Mark E. SaadDirectorSell9,127$125.07$1,141,513.8910,002View SEC Filing Icon  
9/2/2025Roger JeffsDirectorSell13,464$123.68$1,665,227.5257,510View SEC Filing Icon  
8/28/2025Roger JeffsDirectorSell20,000$121.60$2,432,000.0090,974View SEC Filing Icon  
8/26/2025Roger JeffsDirectorSell20,000$120.03$2,400,600.00110,974View SEC Filing Icon  
8/22/2025Roger JeffsDirectorSell16,694$120.08$2,004,615.52150,974View SEC Filing Icon  
6/23/2025Hunter R. MurdockGeneral CounselSell6,014$100.12$602,121.68View SEC Filing Icon  
6/20/2025Hunter R. MurdockGeneral CounselSell7,500$102.47$768,525.00View SEC Filing Icon  
6/17/2025Hunter R. MurdockGeneral CounselSell7,500$100.26$751,950.00View SEC Filing Icon  
6/9/2025Mark L. JacobsonCOOSell25,000$110.44$2,761,000.005,783View SEC Filing Icon  
5/28/2025Mark L. JacobsonCOOSell20,000$103.45$2,069,000.005,783View SEC Filing Icon  
5/27/2025Mark ColemanDirectorSell3,750$105.47$395,512.5050,387View SEC Filing Icon  
5/27/2025Mark L. JacobsonCOOSell20,673$104.66$2,163,636.185,783View SEC Filing Icon  
5/20/2025Mark ColemanDirectorSell3,000$107.49$322,470.0054,137View SEC Filing Icon  
2/14/2025Nick PizzieCFOSell3,000$131.07$393,210.0042,187View SEC Filing Icon  
9/11/2024Mark E. SaadDirectorSell11,016$91.31$1,005,870.9610,002View SEC Filing Icon  
8/9/2024Mark L. JacobsonCOOSell47,739$84.26$4,022,488.145,783View SEC Filing Icon  
5/29/2024Mark L. JacobsonCOOSell7,910$74.31$587,792.105,783View SEC Filing Icon  
5/28/2024Mark ColemanDirectorSell5,249$75.21$394,777.2919,848View SEC Filing Icon  
4/1/2024Mark L. JacobsonCOOSell24,662$77.24$1,904,892.88View SEC Filing Icon  
3/14/2024Roger JeffsDirectorSell29,976$69.70$2,089,327.20120,756View SEC Filing Icon  
9/15/2023Mark ColemanDirectorSell11,016$75.19$828,293.0425,097View SEC Filing Icon  
See Full Table

SEC Filings (Institutional Ownership Changes) for Axsome Therapeutics (NASDAQ:AXSM)

81.49% of Axsome Therapeutics stock is owned by institutions. Institutional ownership can be a sign of analyst confidence in the fundamentals of the stock.

Institutional Buying and Selling by Quarter

This chart shows the instiutional buying and selling at AXSM by year and by quarter.

Skip Institutional Buying and Selling Chart and Table DataRead Chart Data in Institutional Trading History Table

Axsome Therapeutics Institutional Trading History

Reporting DateHedge FundShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
12/2/2025Allworth Financial LP1,442$0.18M0.0%+6.6%0.003%Search for SEC Filing on Google Icon
12/2/2025IFP Advisors Inc63,284$7.69M0.2%-1.1%0.126%Search for SEC Filing on Google Icon
11/24/2025CIBC Private Wealth Group LLC14,375$1.75M0.0%+5.0%0.029%Search for SEC Filing on Google Icon
11/21/2025CIBC Bancorp USA Inc.4,314$0.52M0.0%N/A0.009%Search for SEC Filing on Google Icon
11/20/2025Wilmington Savings Fund Society FSB716$87K0.0%+4,375.0%0.001%Search for SEC Filing on Google Icon
11/18/2025Advisory Services Network LLC330$40K0.0%N/A0.001%Search for SEC Filing on Google Icon
11/17/2025Castleark Management LLC15,143$1.84M0.1%-60.2%0.030%Search for SEC Filing on Google Icon
11/17/2025CANADA LIFE ASSURANCE Co8,991$1.06M0.0%+21.4%0.018%Search for SEC Filing on Google Icon
11/17/2025Woodline Partners LP331,864$40.31M0.2%+0.2%0.658%Search for SEC Filing on Google Icon
11/17/2025Dark Forest Capital Management LP7,267$0.88M0.0%-57.0%0.014%Search for SEC Filing on Google Icon
11/17/2025Voleon Capital Management LP16,734$2.03M0.0%N/A0.033%Search for SEC Filing on Google Icon
11/17/2025Verition Fund Management LLC1,989$0.24M0.0%N/A0.004%Search for SEC Filing on Google Icon
11/17/2025Vestal Point Capital LP150,000$18.22M0.8%N/A0.298%Search for SEC Filing on Google Icon
11/17/2025Quarry LP1,250$0.15M0.0%-50.0%0.002%Search for SEC Filing on Google Icon
11/17/2025Qube Research & Technologies Ltd325,626$39.55M0.0%-16.9%0.646%Search for SEC Filing on Google Icon
11/17/2025Northern Trust Corp409,535$49.74M0.0%+0.0%0.812%Search for SEC Filing on Google Icon
11/17/2025Mariner LLC16,617$2.02M0.0%+6.6%0.033%Search for SEC Filing on Google Icon
11/17/2025Mercer Global Advisors Inc. ADV1,962$0.24M0.0%N/A0.004%Search for SEC Filing on Google Icon
11/17/2025Millennium Management LLC5,741$0.70M0.0%-81.3%0.011%Search for SEC Filing on Google Icon
11/17/2025MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.18,802$2.28M0.0%-15.2%0.037%Search for SEC Filing on Google Icon
11/17/2025Jain Global LLC9,007$1.09M0.0%N/A0.018%Search for SEC Filing on Google Icon
11/17/2025HighVista Strategies LLC9,348$1.14M0.3%-14.3%0.019%Search for SEC Filing on Google Icon
11/17/2025Eventide Asset Management LLC746,398$90.64M1.5%+2.9%1.481%Search for SEC Filing on Google Icon
11/17/2025Brevan Howard Capital Management LP7,334$0.89M0.0%-50.4%0.015%Search for SEC Filing on Google Icon
11/17/2025Bank of America Corp DE361,261$43.88M0.0%-52.1%0.717%Search for SEC Filing on Google Icon
11/17/2025Aquatic Capital Management LLC7,426$0.90M0.0%-68.6%0.015%Search for SEC Filing on Google Icon
11/17/2025Algert Global LLC44,150$5.36M0.1%+18.0%0.088%Search for SEC Filing on Google Icon
11/17/2025Alliancebernstein L.P.63,065$7.66M0.0%+37.2%0.125%Search for SEC Filing on Google Icon
11/17/2025Ameriprise Financial Inc.108,236$13.15M0.0%+54.4%0.215%Search for SEC Filing on Google Icon
11/14/2025Creative Planning21,278$2.58M0.0%+32.3%0.042%Search for SEC Filing on Google Icon
11/14/2025Lazard Asset Management LLC21,837$2.65M0.0%-25.5%0.043%Search for SEC Filing on Google Icon
11/14/2025SummitTX Capital L.P.15,350$1.86M0.1%+466.6%0.030%Search for SEC Filing on Google Icon
11/14/2025Raymond James Financial Inc.158,689$19.27M0.0%-1.7%0.315%Search for SEC Filing on Google Icon
11/14/2025Bellevue Group AG52,335$6.36M0.1%-7.0%0.104%Search for SEC Filing on Google Icon
11/14/2025Deep Track Capital LP900,000$109.31M3.1%+12.3%1.785%Search for SEC Filing on Google Icon
11/14/2025Freestone Grove Partners LP2,494$0.30M0.0%N/A0.005%Search for SEC Filing on Google Icon
11/14/2025Man Group plc287,908$34.97M0.1%-45.2%0.571%Search for SEC Filing on Google Icon
11/14/2025Orbimed Advisors LLC531,800$64.59M1.6%+24.3%1.055%Search for SEC Filing on Google Icon
11/14/2025Zurcher Kantonalbank Zurich Cantonalbank 6,989$0.85M0.0%+8.4%0.014%Search for SEC Filing on Google Icon
11/14/2025UBS AM A Distinct Business Unit of UBS Asset Management Americas LLC86,691$10.53M0.0%-35.4%0.172%Search for SEC Filing on Google Icon
11/14/2025Two Sigma Investments LP8,207$1M0.0%N/A0.016%Search for SEC Filing on Google Icon
11/14/2025Wellington Management Group LLP1,334,560$162.08M0.0%+84.1%2.647%Search for SEC Filing on Google Icon
11/14/2025Comerica Bank12,758$1.55M0.0%+275.7%0.025%Search for SEC Filing on Google Icon
11/14/2025Perbak Capital Partners LLP6,313$0.77M0.1%+33.5%0.013%Search for SEC Filing on Google Icon
11/14/2025F m Investments LLC39,495$4.80M0.2%+22.6%0.078%Search for SEC Filing on Google Icon
11/14/2025Glenmede Investment Management LP7,232$0.88M0.0%-12.7%0.014%Search for SEC Filing on Google Icon
11/13/2025Jump Financial LLC25,000$3.04M0.0%-80.5%0.050%Search for SEC Filing on Google Icon
11/13/2025Marshall Wace LLP378,024$45.91M0.0%+566.5%0.750%Search for SEC Filing on Google Icon
11/13/2025Landscape Capital Management L.L.C.19,288$2.34M0.1%+237.9%0.038%Search for SEC Filing on Google Icon
11/13/2025Kennedy Capital Management LLC38,774$4.71M0.1%+38.7%0.077%Search for SEC Filing on Google Icon
11/13/2025Tocqueville Asset Management L.P.5,650$0.69M0.0%+8.7%0.011%Search for SEC Filing on Google Icon
11/13/2025Johnson Financial Group Inc.503$61K0.0%N/A0.001%Search for SEC Filing on Google Icon
11/13/2025Quantitative Investment Management LLC2,095$0.25M0.0%N/A0.004%Search for SEC Filing on Google Icon
11/13/2025Invesco Ltd.990,557$120.30M0.0%+73.3%1.965%Search for SEC Filing on Google Icon
11/13/2025Sei Investments Co.48,127$5.85M0.0%+9.5%0.095%Search for SEC Filing on Google Icon
11/13/2025UBS Group AG212,451$25.80M0.0%-64.3%0.421%Search for SEC Filing on Google Icon
11/13/2025Connor Clark & Lunn Investment Management Ltd.209,069$25.39M0.1%-7.0%0.415%Search for SEC Filing on Google Icon
11/13/2025Atika Capital Management LLC49,000$5.95M0.5%+6.2%0.097%Search for SEC Filing on Google Icon
11/13/2025Capital Fund Management S.A.28,758$3.49M0.0%-52.7%0.057%Search for SEC Filing on Google Icon
11/13/2025BNP Paribas Financial Markets190,106$23.09M0.0%+2.0%0.377%Search for SEC Filing on Google Icon
11/13/2025Mackenzie Financial Corp3,382$0.41M0.0%+48.0%0.007%Search for SEC Filing on Google Icon
11/13/2025Franklin Resources Inc.285,598$34.69M0.0%+2.5%0.567%Search for SEC Filing on Google Icon
11/13/2025Van ECK Associates Corp14,873$1.81M0.0%-8.9%0.030%Search for SEC Filing on Google Icon
11/13/2025Legal & General Group Plc37,785$4.59M0.0%-6.1%0.075%Search for SEC Filing on Google Icon
11/13/2025Swiss National Bank66,800$8.11M0.0%+2.5%0.133%Search for SEC Filing on Google Icon
11/13/2025Russell Investments Group Ltd.25,602$3.11M0.0%+43.8%0.051%Search for SEC Filing on Google Icon
11/13/2025Inceptionr LLC8,659$1.05M0.3%N/A0.017%Search for SEC Filing on Google Icon
11/13/2025Rhenman & Partners Asset Management AB172,800$20.99M2.3%+90.3%0.343%Search for SEC Filing on Google Icon
11/13/2025Blair William & Co. IL50,077$6.08M0.0%+1.2%0.099%Search for SEC Filing on Google Icon
11/13/2025First Trust Advisors LP37,137$4.51M0.0%-40.3%0.074%Search for SEC Filing on Google Icon
11/12/2025Barclays PLC72,067$8.75M0.0%-26.1%0.143%Search for SEC Filing on Google Icon
11/12/2025Pitcairn Co.6,106$0.74M0.1%-28.3%0.012%Search for SEC Filing on Google Icon
11/12/2025Dimensional Fund Advisors LP19,192$2.33M0.0%+161.4%0.038%Search for SEC Filing on Google Icon
11/12/2025Legato Capital Management LLC5,051$0.61M0.1%+17.4%0.010%Search for SEC Filing on Google Icon
11/12/2025Victory Capital Management Inc.4,740$0.58M0.0%-1.7%0.009%Search for SEC Filing on Google Icon
11/12/2025Royce & Associates LP56,036$6.81M0.1%+117.6%0.111%Search for SEC Filing on Google Icon
11/12/2025Rafferty Asset Management LLC1,742$0.21M0.0%-20.8%0.003%Search for SEC Filing on Google Icon
11/12/2025Quantbot Technologies LP10,877$1.32M0.0%-41.5%0.022%Search for SEC Filing on Google Icon
11/12/2025Handelsbanken Fonder AB11,400$1.39M0.0%+5.6%0.023%Search for SEC Filing on Google Icon
11/12/2025DNB Asset Management AS101,981$12.39M0.0%+33.1%0.202%Search for SEC Filing on Google Icon
11/12/2025Intech Investment Management LLC16,049$1.95M0.0%-30.1%0.032%Search for SEC Filing on Google Icon
11/12/2025US Bancorp DE131,533$15.98M0.0%+0.5%0.261%Search for SEC Filing on Google Icon
11/10/2025Optiver Holding B.V.288$35K0.0%+82.3%0.001%Search for SEC Filing on Google Icon
11/10/2025TD Asset Management Inc44,192$5.37M0.0%+107.7%0.088%Search for SEC Filing on Google Icon
11/10/2025Dana Investment Advisors Inc.33,612$4.08M0.1%+39.6%0.067%Search for SEC Filing on Google Icon
11/10/2025Clearstead Advisors LLC1,328$0.16M0.0%+11.4%0.003%Search for SEC Filing on Google Icon
11/10/2025Granite Investment Partners LLC88,558$10.76M0.6%-31.1%0.176%Search for SEC Filing on Google Icon
11/10/2025Ameritas Investment Partners Inc.3,381$0.41M0.0%-18.2%0.007%Search for SEC Filing on Google Icon
11/10/2025OneDigital Investment Advisors LLC9,805$1.19M0.0%+5.3%0.019%Search for SEC Filing on Google Icon
11/10/2025Intrust Bank NA3,764$0.46M0.0%+30.9%0.007%Search for SEC Filing on Google Icon
11/10/2025Citigroup Inc.142,013$17.25M0.0%+67.1%0.282%Search for SEC Filing on Google Icon
11/10/2025Lion Street Advisors LLC14,677$1.78M0.6%+62.0%0.029%Search for SEC Filing on Google Icon
11/10/2025China Universal Asset Management Co. Ltd.8,747$1.06M0.1%-11.5%0.017%Search for SEC Filing on Google Icon
11/7/2025Synovus Financial Corp22,156$2.69M0.0%-0.8%0.044%Search for SEC Filing on Google Icon
11/7/2025Readystate Asset Management LP17,860$2.17M0.1%-81.1%0.036%Search for SEC Filing on Google Icon
11/7/2025GSA Capital Partners LLP4,767$0.58M0.0%N/A0.010%Search for SEC Filing on Google Icon
11/7/2025Vanguard Group Inc.4,180,646$507.74M0.0%+6.0%8.378%Search for SEC Filing on Google Icon
11/7/2025Pallas Capital Advisors LLC39,444$4.79M0.2%+4.4%0.079%Search for SEC Filing on Google Icon
11/7/2025JPMorgan Chase & Co.250,513$30.43M0.0%+42.6%0.502%Search for SEC Filing on Google Icon
11/7/2025State of New Jersey Common Pension Fund D18,158$2.21M0.0%+0.6%0.036%Search for SEC Filing on Google Icon
Data available starting January 2016

See Full Table
Axsome Therapeutics logo
Axsome Therapeutics, Inc., a biopharmaceutical company, engages in the development of novel therapies for central nervous system (CNS) disorders in the United States. The company's commercial product portfolio includes Auvelity (dextromethorphan-bupropion), a N-methyl-D-aspartate receptor antagonist with multimodal activity indicated for the treatment of major depressive disorder; and Sunosi (solriamfetol), a medication indicated to the treatment of excessive daytime sleepiness in patients with narcolepsy or obstructive sleep apnea. It is also developing AXS-05, which is in Phase III clinical trial to treat Alzheimer's disease agitation, as well as that has completed phase II clinical trial for the treatment of smoking cessation; AXS-07, an investigational medicine that has completed Phase III trials for the acute treatment of migraine; AXS-12, an investigational medicine, which is in Phase III trial to treat narcolepsy; AXS-14, a selective and potent norepinephrine reuptake inhibitor that has completed Phase III trial for the treatment of fibromyalgia and other conditions; and solriamfetol, a dual-acting dopamine and norepinephrine reuptake inhibitor, which has completed a Phase 2 trial for treating attention-deficit/hyperactivity disorder, and is in phase 2 major depressive, binge eating, and shift work disorder. Axsome Therapeutics, Inc. has a research collaboration agreement with Duke University for evaluating AXS-05 in smoking cessation. The company was incorporated in 2012 and is based in New York, New York.
Read More on Axsome Therapeutics

Today's Range

Now: $148.04
Low: $147.50
High: $149.93

50 Day Range

MA: $134.32
Low: $116.76
High: $151.56

52 Week Range

Now: $148.04
Low: $75.56
High: $152.94

Volume

358,671 shs

Average Volume

538,108 shs

Market Capitalization

$7.46 billion

P/E Ratio

N/A

Dividend Yield

N/A

Beta

0.48

Who are the company insiders with the largest holdings of Axsome Therapeutics?

Axsome Therapeutics' top insider investors include:
  1. Roger Jeffs (Director)
  2. Mark Coleman (Director)
  3. Nick Pizzie (CFO)
  4. Mark E Saad (Director)
  5. Herriot Tabuteau (CEO)
  6. Mark L Jacobson (COO)
  7. Hunter R Murdock (General Counsel)
  8. Mark L Jacobson (COO)
Learn More about top insider investors at Axsome Therapeutics.

Who are the major institutional investors of Axsome Therapeutics?

Axsome Therapeutics' top institutional shareholders include:
  1. Vanguard Group Inc. — 8.38%
  2. Wellington Management Group LLP — 2.65%
  3. Invesco Ltd. — 1.96%
  4. Deep Track Capital LP — 1.79%
  5. Eventide Asset Management LLC — 1.48%
  6. Orbimed Advisors LLC — 1.05%
Learn More about top institutional investors of Axsome Therapeutics stock.

Which institutional investors are selling Axsome Therapeutics stock?

During the last quarter, AXSM stock was sold by these institutional investors:
  1. Bank of America Corp DE
  2. UBS Group AG
  3. Man Group plc
  4. Jump Financial LLC
  5. Readystate Asset Management LP
  6. Qube Research & Technologies Ltd
  7. UBS AM A Distinct Business Unit of UBS Asset Management Americas LLC
  8. Granite Investment Partners LLC
During the last year, company insiders that have sold Axsome Therapeutics company stock include:
  1. Roger Jeffs (Director)
  2. Mark Coleman (Director)
  3. Nick Pizzie (CFO)
  4. Mark E Saad (Director)
  5. Herriot Tabuteau (CEO)
  6. Mark L Jacobson (COO)
  7. Hunter R Murdock (General Counsel)
Learn More investors selling Axsome Therapeutics stock.

Which institutional investors are buying Axsome Therapeutics stock?

Within the previous quarter, AXSM stock was bought by institutional investors including:
  1. Wellington Management Group LLP
  2. Invesco Ltd.
  3. Marshall Wace LLP
  4. Vanguard Group Inc.
  5. Vestal Point Capital LP
  6. Assenagon Asset Management S.A.
  7. Orbimed Advisors LLC
  8. Deep Track Capital LP