| 11/17/2025 | Woodline Partners LP | 42,698 | $1.68M | 0.0% | -89.3% | 0.100% |  |
| 11/17/2025 | TCG Crossover Management LLC | 1,676,624 | $65.98M | 3.2% | +11.7% | 3.910% |  |
| 11/17/2025 | Vivo Capital LLC | 353,998 | $13.93M | 1.1% | N/A | 0.826% |  |
| 11/17/2025 | Vestal Point Capital LP | 1,180,000 | $46.43M | 2.1% | -63.1% | 2.752% |  |
| 11/17/2025 | Polar Capital Holdings Plc | 748,003 | $29.43M | 0.1% | N/A | 1.744% |  |
| 11/17/2025 | Nantahala Capital Management LLC | 375,000 | $14.76M | 0.5% | N/A | 0.875% |  |
| 11/17/2025 | Millennium Management LLC | 146,166 | $5.75M | 0.0% | -25.2% | 0.341% |  |
| 11/17/2025 | MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 8,405 | $0.33M | 0.0% | -30.5% | 0.020% |  |
| 11/17/2025 | Jain Global LLC | 11,124 | $0.44M | 0.0% | N/A | 0.026% |  |
| 11/17/2025 | HighVista Strategies LLC | 54,225 | $2.13M | 0.5% | +241.9% | 0.126% |  |
| 11/17/2025 | Fred Alger Management LLC | 45,304 | $1.78M | 0.0% | N/A | 0.106% |  |
| 11/17/2025 | Fairmount Funds Management LLC | 3,307,191 | $130.14M | 11.7% | +22.2% | 7.713% |  |
| 11/17/2025 | Brevan Howard Capital Management LP | 11,930 | $0.47M | 0.0% | N/A | 0.028% |  |
| 11/17/2025 | Bank of America Corp DE | 180,025 | $7.08M | 0.0% | +9.0% | 0.420% |  |
| 11/17/2025 | Boothbay Fund Management LLC | 138,963 | $5.47M | 0.1% | N/A | 0.324% |  |
| 11/17/2025 | Braidwell LP | 835,057 | $32.86M | 1.0% | N/A | 1.947% |  |
| 11/17/2025 | Alliancebernstein L.P. | 852,384 | $33.54M | 0.0% | -27.4% | 1.988% |  |
| 11/17/2025 | Ameriprise Financial Inc. | 103,755 | $4.08M | 0.0% | +84.4% | 0.242% |  |
| 11/14/2025 | Schonfeld Strategic Advisors LLC | 128,253 | $5.05M | 0.0% | -25.5% | 0.299% |  |
| 11/14/2025 | Raymond James Financial Inc. | 11,245 | $0.44M | 0.0% | +686.4% | 0.035% |  |
| 11/14/2025 | Acuta Capital Partners LLC | 25,000 | $0.98M | 1.0% | N/A | 0.078% |  |
| 11/14/2025 | Balyasny Asset Management L.P. | 443,703 | $17.46M | 0.0% | N/A | 1.378% |  |
| 11/14/2025 | Longaeva Partners L.P. | 25,000 | $0.98M | 0.1% | N/A | 0.078% |  |
| 11/14/2025 | Brooklyn Investment Group | 6,652 | $0.26M | 0.0% | N/A | 0.021% |  |
| 11/14/2025 | Integral Health Asset Management LLC | 150,000 | $5.90M | 0.4% | N/A | 0.466% |  |
| 11/14/2025 | Wellington Management Group LLP | 2,577,662 | $101.43M | 0.0% | +3,366.9% | 8.008% |  |
| 11/14/2025 | Glenmede Investment Management LP | 5,415 | $0.21M | 0.0% | N/A | 0.017% |  |
| 11/13/2025 | Marshall Wace LLP | 572,938 | $22.55M | 0.0% | N/A | 1.780% |  |
| 11/13/2025 | Sei Investments Co. | 14,275 | $0.56M | 0.0% | N/A | 0.044% |  |
| 11/13/2025 | UBS Group AG | 137,073 | $5.39M | 0.0% | +4.3% | 0.426% |  |
| 11/13/2025 | BNP Paribas Financial Markets | 34,593 | $1.36M | 0.0% | -30.2% | 0.107% |  |
| 11/13/2025 | Franklin Resources Inc. | 450,311 | $17.72M | 0.0% | N/A | 1.399% |  |
| 11/13/2025 | Legal & General Group Plc | 1,497 | $59K | 0.0% | -18.2% | 0.005% |  |
| 11/13/2025 | Russell Investments Group Ltd. | 1,618 | $64K | 0.0% | N/A | 0.005% |  |
| 11/13/2025 | Rhenman & Partners Asset Management AB | 173,627 | $6.83M | 0.8% | +37.1% | 0.539% |  |
| 11/13/2025 | Blair William & Co. IL | 15,875 | $0.63M | 0.0% | N/A | 0.049% |  |
| 11/12/2025 | Barclays PLC | 204,369 | $8.04M | 0.0% | +215.3% | 0.635% |  |
| 11/12/2025 | Dimensional Fund Advisors LP | 8,689 | $0.34M | 0.0% | N/A | 0.027% |  |
| 11/12/2025 | Rafferty Asset Management LLC | 17,331 | $0.68M | 0.0% | -39.2% | 0.054% |  |
| 11/10/2025 | TD Asset Management Inc | 27,658 | $1.09M | 0.0% | N/A | 0.086% |  |
| 11/10/2025 | Palumbo Wealth Management LLC | 6,650 | $0.26M | 0.1% | N/A | 0.021% |  |
| 11/10/2025 | Patient Square Capital LP | 125,000 | $4.92M | 1.3% | N/A | 0.388% |  |
| 11/10/2025 | Ameritas Investment Partners Inc. | 1,373 | $54K | 0.0% | -41.4% | 0.004% |  |
| 11/10/2025 | Citigroup Inc. | 68,479 | $2.70M | 0.0% | +486.8% | 0.213% |  |
| 11/7/2025 | Vanguard Group Inc. | 1,642,198 | $64.62M | 0.0% | +13.6% | 5.102% |  |
| 11/7/2025 | JPMorgan Chase & Co. | 68,124 | $2.68M | 0.0% | +626.4% | 0.212% |  |
| 11/6/2025 | Rhumbline Advisers | 26,003 | $1.02M | 0.0% | -17.5% | 0.081% |  |
| 11/6/2025 | Candriam S.C.A. | 301,428 | $11.86M | 0.1% | +25.3% | 0.936% |  |
| 11/5/2025 | Alps Advisors Inc. | 15,631 | $0.62M | 0.0% | -10.0% | 0.049% |  |
| 11/5/2025 | Bessemer Group Inc. | 16,134 | $0.64M | 0.0% | +7.8% | 0.050% |  |
| 11/5/2025 | Envestnet Asset Management Inc. | 5,882 | $0.23M | 0.0% | N/A | 0.018% |  |
| 11/3/2025 | AlphaQuest LLC | 1,331 | $52K | 0.0% | -73.5% | 0.004% |  |
| 11/3/2025 | New York State Common Retirement Fund | 6,900 | $0.27M | 0.0% | +68.3% | 0.021% |  |
| 10/31/2025 | Y Intercept Hong Kong Ltd | 18,568 | $0.73M | 0.0% | N/A | 0.058% |  |
| 10/30/2025 | Parkside Financial Bank & Trust | 950 | $37K | 0.0% | +131.7% | 0.003% |  |
| 10/30/2025 | Universal Beteiligungs und Servicegesellschaft mbH | 15,734 | $0.62M | 0.0% | N/A | 0.049% |  |
| 10/21/2025 | Moody Aldrich Partners LLC | 43,291 | $1.70M | 0.3% | -40.9% | 0.134% |  |
| 10/17/2025 | Ethic Inc. | 5,530 | $0.22M | 0.0% | N/A | 0.017% |  |
| 8/18/2025 | Hudson Bay Capital Management LP | 115,425 | $2.15M | 0.0% | +53.9% | 0.359% |  |
| 8/15/2025 | Tower Research Capital LLC TRC | 4,320 | $80K | 0.0% | +330.7% | 0.013% |  |
| 8/15/2025 | Vestal Point Capital LP | 3,200,000 | $59.62M | 3.1% | +88.2% | 9.941% |  |
| 8/15/2025 | Rafferty Asset Management LLC | 28,522 | $0.53M | 0.0% | +19.5% | 0.089% |  |
| 8/15/2025 | Hudson Bay Capital Management LP | 115,425 | $2.15M | 0.0% | +53.9% | 0.359% |  |
| 8/15/2025 | BNP Paribas Financial Markets | 49,531 | $0.92M | 0.0% | +3,547.3% | 0.154% |  |
| 8/15/2025 | Bain Capital Life Sciences Investors LLC | 2,482,250 | $46.24M | 5.8% | -7.7% | 7.711% |  |
| 8/15/2025 | Bank of America Corp DE | 165,125 | $3.08M | 0.0% | +77.0% | 0.513% |  |
| 8/15/2025 | 5AM Venture Management LLC | 984,725 | $18.35M | 7.1% | -4.2% | 3.059% |  |
| 8/15/2025 | Adage Capital Partners GP L.L.C. | 185,000 | $3.45M | 0.0% | -2.1% | 0.575% |  |
| 8/15/2025 | Ameriprise Financial Inc. | 56,261 | $1.05M | 0.0% | N/A | 0.175% |  |
| 8/14/2025 | Paloma Partners Management Co | 29,214 | $0.54M | 0.1% | N/A | 0.091% |  |
| 8/14/2025 | Raymond James Financial Inc. | 1,430 | $27K | 0.0% | N/A | 0.004% |  |
| 8/14/2025 | MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 12,091 | $0.22M | 0.0% | -21.1% | 0.038% |  |
| 8/14/2025 | Alliancebernstein L.P. | 1,174,822 | $21.89M | 0.0% | +14.5% | 3.650% |  |
| 8/14/2025 | HighVista Strategies LLC | 15,861 | $0.30M | 0.1% | -49.5% | 0.049% |  |
| 8/13/2025 | Walleye Capital LLC | 26,133 | $0.49M | 0.0% | -75.6% | 0.081% |  |
| 8/13/2025 | Invesco Ltd. | 20,940 | $0.39M | 0.0% | +31.1% | 0.065% |  |
| 8/13/2025 | Sio Capital Management LLC | 236,070 | $4.40M | 1.7% | +101.8% | 0.733% |  |
| 8/13/2025 | New York State Common Retirement Fund | 4,100 | $76K | 0.0% | -57.7% | 0.013% |  |
| 8/13/2025 | Virtus Investment Advisers LLC | 4,875 | $91K | 0.0% | -30.2% | 0.015% |  |
| 8/12/2025 | XTX Topco Ltd | 27,003 | $0.50M | 0.0% | N/A | 0.084% |  |
| 8/12/2025 | American Century Companies Inc. | 54,140 | $1.01M | 0.0% | +13.2% | 0.168% |  |
| 8/12/2025 | Rhumbline Advisers | 31,501 | $0.59M | 0.0% | -10.1% | 0.098% |  |
| 8/12/2025 | Legal & General Group Plc | 1,829 | $34K | 0.0% | -53.0% | 0.006% |  |
| 8/12/2025 | JPMorgan Chase & Co. | 9,378 | $0.18M | 0.0% | -19.7% | 0.029% |  |
| 8/12/2025 | Ensign Peak Advisors Inc | 134,416 | $2.50M | 0.0% | N/A | 0.418% |  |
| 8/8/2025 | Candriam S.C.A. | 240,576 | $4.48M | 0.0% | -3.2% | 0.748% |  |
| 8/8/2025 | Police & Firemen s Retirement System of New Jersey | 4,230 | $79K | 0.0% | -26.6% | 0.013% |  |
| 8/8/2025 | Geode Capital Management LLC | 484,900 | $9.04M | 0.0% | -6.2% | 1.508% |  |
| 8/4/2025 | Moody Aldrich Partners LLC | 73,266 | $1.37M | 0.3% | -1.5% | 0.228% |  |
| 7/31/2025 | AlphaQuest LLC | 5,028 | $94K | 0.0% | N/A | 0.016% |  |
| 6/27/2025 | Goldman Sachs Group Inc. | 73,430 | $1.33M | 0.0% | -64.7% | 0.228% |  |
| 5/29/2025 | Rhumbline Advisers | 35,045 | $0.64M | 0.0% | -2.5% | 0.109% |  |
| 5/16/2025 | Octagon Capital Advisors LP | 2,341,667 | $42.48M | 4.5% | +11.0% | 7.289% |  |
| 5/16/2025 | Goldman Sachs Group Inc. | 73,430 | $1.33M | 0.0% | -64.7% | 0.229% |  |
| 5/16/2025 | MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 15,334 | $0.28M | 0.0% | +4.2% | 0.048% |  |
| 5/16/2025 | Alliancebernstein L.P. | 1,025,622 | $18.61M | 0.0% | -11.6% | 3.192% |  |
| 5/16/2025 | Ally Bridge Group NY LLC | 80,584 | $1.46M | 1.3% | -24.3% | 0.251% |  |
| 5/16/2025 | Adage Capital Partners GP L.L.C. | 189,000 | $3.43M | 0.0% | +5.0% | 0.588% |  |
| 5/16/2025 | ADAR1 Capital Management LLC | 18,285 | $0.33M | 0.1% | +3.4% | 0.057% |  |
| 5/15/2025 | Vestal Point Capital LP | 1,700,069 | $30.84M | 2.2% | +58.1% | 5.292% |  |