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KRYS Insider Trading

Insider Ownership Percentage: 13.70%
Insider Buying (Last 12 Months): $0.00
Insider Selling (Last 12 Months): $16,183,607.91

Krystal Biotech Insider Trading History Chart

This chart shows the insider buying and selling history at Krystal Biotech by year and by quarter.

Skip ChartChart Data in Insider Trading History Table

Krystal Biotech Share Price & Price History

Current Price: $221.96
Price Change: ▲ Price Increase of +4.5 (2.07%)
As of 12/4/2025 05:00 PM ET

This chart shows the closing price history over time for KRYS up to the past year.

Skip Chart and Table DataPrice Data in Insider Trading History Table
Days: 30 | 90 | 365

Krystal Biotech Insider Trading History

Transaction DateInsider NameTitleBuy/SellNumber of SharesAverage Share PriceTotal TransactionShares Held After TransactionDetails
7/16/2025Suma KrishnanInsiderSell1,529$150.00$229,350.001,438,711View SEC Filing Icon  
7/16/2025Suma KrishnanInsiderSell1,389$150.00$208,350.001,508,056View SEC Filing Icon  
7/15/2025Suma KrishnanInsiderSell3,036$150.98$458,375.281,440,240View SEC Filing Icon  
7/15/2025Suma KrishnanInsiderSell3,084$151.01$465,714.841,509,445View SEC Filing Icon  
7/14/2025Suma KrishnanInsiderSell13,435$150.30$2,019,280.501,443,276View SEC Filing Icon  
7/14/2025Suma KrishnanInsiderSell13,400$150.30$2,014,020.001,512,529View SEC Filing Icon  
7/10/2025Suma KrishnanInsiderSell6,800$150.28$1,021,904.001,456,711View SEC Filing Icon  
7/10/2025Suma KrishnanInsiderSell6,927$150.27$1,040,920.291,525,929View SEC Filing Icon  
7/9/2025Suma KrishnanInsiderSell200$150.14$30,028.001,463,511View SEC Filing Icon  
3/13/2025Suma KrishnanInsiderSell25,000$177.79$4,444,750.001,463,711View SEC Filing Icon  
2/27/2025Kathryn RomanoCAOSell750$175.22$131,415.0012,604View SEC Filing Icon  
12/13/2024Suma KrishnanInsiderSell25,000$164.78$4,119,500.001,475,882View SEC Filing Icon  
9/12/2024Suma KrishnanInsiderSell25,000$197.76$4,944,000.001,500,882View SEC Filing Icon  
6/11/2024Suma KrishnanInsiderSell25,000$175.76$4,394,000.001,525,882View SEC Filing Icon  
5/20/2024Julian S. GangolliDirectorSell20,000$164.13$3,282,600.00View SEC Filing Icon  
3/11/2024Suma KrishnanInsiderSell25,000$170.96$4,274,000.001,550,882View SEC Filing Icon  
2/28/2024Kathryn RomanoCAOSell5,000$165.88$829,400.0012,936View SEC Filing Icon  
2/26/2024Kathryn RomanoCAOSell8,087$136.91$1,107,191.1712,556View SEC Filing Icon  
1/22/2024Kathryn RomanoCAOSell2,500$130.00$325,000.0012,556View SEC Filing Icon  
12/11/2023Suma KrishnanInsiderSell25,000$105.67$2,641,750.001,574,206View SEC Filing Icon  
9/11/2023Suma KrishnanInsiderSell25,000$127.23$3,180,750.001,599,206View SEC Filing Icon  
6/9/2023Andrew C OrthInsiderSell12,500$128.61$1,607,625.00100View SEC Filing Icon  
6/8/2023Daniel JanneyDirectorSell31,065$128.11$3,979,737.15126,297View SEC Filing Icon  
5/31/2023Suma KrishnanInsiderSell25,000$116.16$2,904,000.001,624,206View SEC Filing Icon  
5/22/2023Kathryn RomanoCAOSell25,000$109.04$2,726,000.0012,556View SEC Filing Icon  
5/19/2023Daniel JanneyDirectorSell50,000$95.02$4,751,000.00157,362View SEC Filing Icon  
5/19/2023Kathryn RomanoCAOSell28,428$95.05$2,702,081.4012,556View SEC Filing Icon  
5/9/2023Daniel JanneyDirectorSell17,100$90.74$1,551,654.00207,362View SEC Filing Icon  
4/19/2023Daniel JanneyDirectorSell7,900$90.32$713,528.00224,462View SEC Filing Icon  
4/17/2023Suma KrishnanInsiderSell25,000$87.65$2,191,250.001,649,206View SEC Filing Icon  
3/1/2023Dino A. RossiDirectorSell40,000$83.25$3,330,000.0083,691View SEC Filing Icon  
1/17/2023Krish S. KrishnanCEOSell22,149$80.77$1,788,974.731,741,539View SEC Filing Icon  
1/17/2023Suma KrishnanInsiderSell22,148$80.77$1,788,893.961,680,115View SEC Filing Icon  
1/4/2023Krish S. KrishnanCEOSell3,748$80.08$300,139.841,763,688View SEC Filing Icon  
1/3/2023Suma KrishnanInsiderSell1,700$80.33$136,561.001,706,201View SEC Filing Icon  
12/16/2022Krish S. KrishnanCEOSell10,572$80.10$846,817.201,777,146View SEC Filing Icon  
12/16/2022Suma KrishnanInsiderSell10,527$80.10$843,212.701,715,913View SEC Filing Icon  
See Full Table

SEC Filings (Institutional Ownership Changes) for Krystal Biotech (NASDAQ:KRYS)

86.29% of Krystal Biotech stock is owned by institutions. Institutional ownership can be a sign of analyst confidence in the fundamentals of the stock.

Institutional Buying and Selling by Quarter

This chart shows the instiutional buying and selling at KRYS by year and by quarter.

Skip Institutional Buying and Selling Chart and Table DataRead Chart Data in Institutional Trading History Table

Krystal Biotech Institutional Trading History

Reporting DateHedge FundShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
11/21/2025CIBC Bancorp USA Inc.2,643$0.47M0.0%N/A0.009%Search for SEC Filing on Google Icon
11/20/2025Wilmington Savings Fund Society FSB393$69K0.0%+78.6%0.001%Search for SEC Filing on Google Icon
11/19/2025Danske Bank A S200$35K0.0%N/A0.001%Search for SEC Filing on Google Icon
11/18/2025Advisory Services Network LLC854$0.15M0.0%N/A0.003%Search for SEC Filing on Google Icon
11/17/2025CANADA LIFE ASSURANCE Co21,398$3.78M0.0%+2.6%0.074%Search for SEC Filing on Google Icon
11/17/2025Dark Forest Capital Management LP5,903$1.04M0.0%+7.2%0.020%Search for SEC Filing on Google Icon
11/17/2025Verition Fund Management LLC31,333$5.53M0.0%+18.2%0.108%Search for SEC Filing on Google Icon
11/17/2025Mariner LLC4,605$0.81M0.0%+8.2%0.016%Search for SEC Filing on Google Icon
11/17/2025Millennium Management LLC148,713$26.25M0.0%+1,083.8%0.513%Search for SEC Filing on Google Icon
11/17/2025Mindset Wealth Management LLC1,470$0.26M0.1%N/A0.005%Search for SEC Filing on Google Icon
11/17/2025MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.13,290$2.35M0.0%-13.0%0.046%Search for SEC Filing on Google Icon
11/17/2025Decheng Capital LLC32,300$5.70M1.0%-51.1%0.111%Search for SEC Filing on Google Icon
11/17/2025Bank of America Corp DE137,995$24.36M0.0%+13.3%0.476%Search for SEC Filing on Google Icon
11/17/2025Boothbay Fund Management LLC8,889$1.57M0.0%N/A0.031%Search for SEC Filing on Google Icon
11/17/2025Braidwell LP520,401$91.87M2.7%-28.5%1.794%Search for SEC Filing on Google Icon
11/17/2025Alliancebernstein L.P.29,920$5.28M0.0%-3.9%0.103%Search for SEC Filing on Google Icon
11/17/2025Ameriprise Financial Inc.55,792$9.85M0.0%-11.2%0.192%Search for SEC Filing on Google Icon
11/14/2025Creative Planning11,609$2.05M0.0%+38.9%0.040%Search for SEC Filing on Google Icon
11/14/2025Raymond James Financial Inc.64,363$11.36M0.0%-6.4%0.222%Search for SEC Filing on Google Icon
11/14/2025Bellevue Group AG1,312$0.23M0.0%+5.0%0.005%Search for SEC Filing on Google Icon
11/14/2025Amundi4,561$0.82M0.0%+8.8%0.016%Search for SEC Filing on Google Icon
11/14/2025Freestone Grove Partners LP2,031$0.36M0.0%+7.2%0.007%Search for SEC Filing on Google Icon
11/14/2025Man Group plc2,088$0.37M0.0%-93.1%0.007%Search for SEC Filing on Google Icon
11/14/2025Orbimed Advisors LLC102,745$18.14M0.4%+1,016.8%0.354%Search for SEC Filing on Google Icon
11/14/2025California State Teachers Retirement System20,882$3.69M0.0%+3.8%0.072%Search for SEC Filing on Google Icon
11/14/2025ADAR1 Capital Management LLC18,523$3.27M0.3%N/A0.064%Search for SEC Filing on Google Icon
11/14/2025Acuta Capital Partners LLC10,573$1.87M1.9%N/A0.036%Search for SEC Filing on Google Icon
11/14/2025UBS AM A Distinct Business Unit of UBS Asset Management Americas LLC202,589$35.76M0.0%-13.5%0.699%Search for SEC Filing on Google Icon
11/14/2025Avoro Capital Advisors LLC2,777,777$490.36M6.3%+4.4%9.579%Search for SEC Filing on Google Icon
11/14/2025Comerica Bank7,151$1.26M0.0%-17.9%0.025%Search for SEC Filing on Google Icon
11/14/2025Regal Investment Advisors LLC4,316$0.76M0.0%-2.7%0.015%Search for SEC Filing on Google Icon
11/13/2025Marshall Wace LLP128,960$22.77M0.0%+14.8%0.445%Search for SEC Filing on Google Icon
11/13/2025Kennedy Capital Management LLC39,291$6.94M0.2%+3.0%0.135%Search for SEC Filing on Google Icon
11/13/2025Invesco Ltd.66,880$11.81M0.0%-5.7%0.231%Search for SEC Filing on Google Icon
11/13/2025Sei Investments Co.23,393$4.13M0.0%+21.2%0.081%Search for SEC Filing on Google Icon
11/13/2025BNP Paribas Financial Markets9,179$1.62M0.0%+27.8%0.032%Search for SEC Filing on Google Icon
11/13/2025Franklin Resources Inc.19,850$3.50M0.0%+7.7%0.068%Search for SEC Filing on Google Icon
11/13/2025Capital World Investors809,240$142.86M0.0%-14.1%2.790%Search for SEC Filing on Google Icon
11/13/2025Legal & General Group Plc65,815$11.62M0.0%-3.8%0.227%Search for SEC Filing on Google Icon
11/13/2025Fieldview Capital Management LLC14,705$2.60M0.4%+1.1%0.051%Search for SEC Filing on Google Icon
11/13/2025Swiss National Bank42,000$7.41M0.0%+1.4%0.145%Search for SEC Filing on Google Icon
11/13/2025WINTON GROUP Ltd8,212$1.45M0.1%N/A0.028%Search for SEC Filing on Google Icon
11/13/2025Russell Investments Group Ltd.26,549$4.69M0.0%+156.3%0.092%Search for SEC Filing on Google Icon
11/13/2025Schroder Investment Management Group10,170$1.80M0.0%-0.6%0.035%Search for SEC Filing on Google Icon
11/13/2025Rhenman & Partners Asset Management AB11,750$2.07M0.2%-7.8%0.041%Search for SEC Filing on Google Icon
11/13/2025Blair William & Co. IL4,752$0.84M0.0%-2.1%0.016%Search for SEC Filing on Google Icon
11/13/2025First Trust Advisors LP248,392$43.85M0.0%+11.7%0.857%Search for SEC Filing on Google Icon
11/12/2025Barclays PLC75,896$13.40M0.0%-18.3%0.262%Search for SEC Filing on Google Icon
11/12/2025Crossmark Global Holdings Inc.2,069$0.37M0.0%-15.8%0.007%Search for SEC Filing on Google Icon
11/12/2025GW&K Investment Management LLC10,492$1.85M0.0%-65.2%0.036%Search for SEC Filing on Google Icon
11/12/2025Dimensional Fund Advisors LP533,964$94.26M0.0%+5.5%1.841%Search for SEC Filing on Google Icon
11/12/2025Legato Capital Management LLC3,757$0.66M0.1%N/A0.013%Search for SEC Filing on Google Icon
11/12/2025Teachers Retirement System of The State of Kentucky7,220$1.28M0.0%-13.3%0.025%Search for SEC Filing on Google Icon
11/12/2025Victory Capital Management Inc.54,816$9.68M0.0%-31.6%0.189%Search for SEC Filing on Google Icon
11/12/2025Segall Bryant & Hamill LLC85,263$15.05M0.2%-42.6%0.294%Search for SEC Filing on Google Icon
11/12/2025William Blair Investment Management LLC149,302$26.36M0.1%+63.9%0.515%Search for SEC Filing on Google Icon
11/12/2025Huntington National Bank190$34K0.0%-25.8%0.001%Search for SEC Filing on Google Icon
11/12/2025Argent Trust Co1,307$0.23M0.0%N/A0.005%Search for SEC Filing on Google Icon
11/12/2025DNB Asset Management AS2,356$0.42M0.0%+36.1%0.008%Search for SEC Filing on Google Icon
11/12/2025Hohimer Wealth Management LLC1,215$0.21M0.0%N/A0.004%Search for SEC Filing on Google Icon
11/12/2025Intech Investment Management LLC9,751$1.72M0.0%-11.2%0.034%Search for SEC Filing on Google Icon
11/12/2025US Bancorp DE310$55K0.0%-38.5%0.001%Search for SEC Filing on Google Icon
11/10/2025MAI Capital Management284$50K0.0%+79.7%0.001%Search for SEC Filing on Google Icon
11/10/2025TD Asset Management Inc45,080$7.96M0.0%+124.5%0.155%Search for SEC Filing on Google Icon
11/10/2025Sound View Wealth Advisors Group LLC2,003$0.35M0.0%+2.9%0.007%Search for SEC Filing on Google Icon
11/10/2025Ameritas Investment Partners Inc.2,072$0.37M0.0%-17.4%0.007%Search for SEC Filing on Google Icon
11/10/2025China Universal Asset Management Co. Ltd.5,073$0.90M0.1%-12.6%0.017%Search for SEC Filing on Google Icon
11/7/2025Fiera Capital Corp15,063$2.66M0.0%-2.9%0.052%Search for SEC Filing on Google Icon
11/7/2025Synovus Financial Corp20,516$3.62M0.0%-0.6%0.071%Search for SEC Filing on Google Icon
11/7/2025CenterBook Partners LP3,429$0.61M0.0%-32.1%0.012%Search for SEC Filing on Google Icon
11/7/2025Readystate Asset Management LP70,349$12.42M0.5%-52.5%0.243%Search for SEC Filing on Google Icon
11/7/2025Vanguard Group Inc.2,792,208$492.91M0.0%-1.1%9.628%Search for SEC Filing on Google Icon
11/7/2025State of New Jersey Common Pension Fund D14,599$2.58M0.0%-2.9%0.050%Search for SEC Filing on Google Icon
11/7/2025PNC Financial Services Group Inc.1,694$0.30M0.0%+19.1%0.006%Search for SEC Filing on Google Icon
11/7/2025TimesSquare Capital Management LLC118,514$20.92M0.3%+3.8%0.409%Search for SEC Filing on Google Icon
11/7/2025Aberdeen Group plc59,372$10.48M0.0%-45.3%0.205%Search for SEC Filing on Google Icon
11/7/2025GF Fund Management CO. LTD.623$0.11M0.0%-15.4%0.002%Search for SEC Filing on Google Icon
11/6/2025Cookson Peirce & Co. Inc.5,654$1M0.0%N/A0.020%Search for SEC Filing on Google Icon
11/6/2025Abich Financial Wealth Management LLC395$70K0.0%N/A0.001%Search for SEC Filing on Google Icon
11/6/2025Public Sector Pension Investment Board100,431$17.73M0.1%+15.9%0.347%Search for SEC Filing on Google Icon
11/6/2025Illinois Municipal Retirement Fund14,245$2.52M0.0%+15.7%0.049%Search for SEC Filing on Google Icon
11/6/2025Rhumbline Advisers70,552$12.46M0.0%-0.3%0.244%Search for SEC Filing on Google Icon
11/6/2025Profund Advisors LLC8,330$1.47M0.0%+2.0%0.029%Search for SEC Filing on Google Icon
11/6/2025ProShare Advisors LLC5,717$1.01M0.0%-13.7%0.020%Search for SEC Filing on Google Icon
11/6/2025Oppenheimer Asset Management Inc.1,263$0.22M0.0%N/A0.004%Search for SEC Filing on Google Icon
11/5/2025Smartleaf Asset Management LLC422$75K0.0%+101.0%0.001%Search for SEC Filing on Google Icon
11/5/2025Alps Advisors Inc.13,367$2.36M0.0%-23.5%0.046%Search for SEC Filing on Google Icon
11/5/2025Bessemer Group Inc.149$26K0.0%+106.9%0.001%Search for SEC Filing on Google Icon
11/5/2025Optimize Financial Inc2,815$0.50M0.3%N/A0.010%Search for SEC Filing on Google Icon
11/5/2025Envestnet Asset Management Inc.13,108$2.31M0.0%-13.3%0.045%Search for SEC Filing on Google Icon
11/5/2025Hantz Financial Services Inc.292$52K0.0%+61.3%0.001%Search for SEC Filing on Google Icon
11/4/2025Principal Financial Group Inc.142,843$25.22M0.0%+1.4%0.494%Search for SEC Filing on Google Icon
11/4/2025Atle Fund Management AB42,191$7.45M2.9%+109.3%0.146%Search for SEC Filing on Google Icon
11/4/2025Transcend Capital Advisors LLC1,680$0.30M0.0%N/A0.006%Search for SEC Filing on Google Icon
11/4/2025Thrivent Financial for Lutherans18,584$3.28M0.0%-0.6%0.064%Search for SEC Filing on Google Icon
11/4/2025Privium Fund Management B.V.12,170$2.15M0.4%+30.6%0.042%Search for SEC Filing on Google Icon
11/3/2025AlphaQuest LLC664$0.12M0.0%+14.7%0.002%Search for SEC Filing on Google Icon
11/3/2025Arizona State Retirement System6,397$1.13M0.0%+1.3%0.022%Search for SEC Filing on Google Icon
11/3/2025New York State Common Retirement Fund26,994$4.77M0.0%+15.4%0.093%Search for SEC Filing on Google Icon
11/3/2025Federated Hermes Inc.23,981$4.23M0.0%-43.9%0.083%Search for SEC Filing on Google Icon
Data available starting January 2016

See Full Table
Krystal Biotech logo
Krystal Biotech, Inc., a commercial-stage biotechnology company, discovers, develops, and commercializes genetic medicines for patients with rare diseases in the United States. It commercializes VYJUVEK (beremagene geperpavec-svdt, or B-VEC) for the treatment of dystrophic epidermolysis bullosa (DEB). The company also develops KB105, which is in Phase 1/2 clinical trials for treating patients with deficient autosomal recessive congenital ichthyosis; KB104 for treating netherton syndrome; KB407 that is in Phase 1 clinical trials for treating cystic fibrosis; KB707 that is in Phase 1 clinical trials for the treatment of anti-PD-1 relapsed/refractory; KB408, which is in Phase 1 clinical trials for treating Alpha-1 antitrypsin deficiency; and KB301 that is in Phase 2 clinical trials for treating aesthetic skin conditions, as well as in open label study with ophthalmic B-VEC for treating for ocular complications of deb. Krystal Biotech, Inc. was founded in 2016 and is headquartered in Pittsburgh, Pennsylvania.
Read More on Krystal Biotech

Today's Range

Now: $221.96
Low: $213.83
High: $222.66

50 Day Range

MA: $196.60
Low: $167.82
High: $221.96

52 Week Range

Now: $221.96
Low: $122.80
High: $222.66

Volume

406,327 shs

Average Volume

234,333 shs

Market Capitalization

$6.44 billion

P/E Ratio

33.28

Dividend Yield

N/A

Beta

0.48

Who are the company insiders with the largest holdings of Krystal Biotech?

Krystal Biotech's top insider investors include:
  1. Suma Krishnan (Insider)
  2. Kathryn Romano (CAO)
  3. Julian S Gangolli (Director)
Learn More about top insider investors at Krystal Biotech.

Who are the major institutional investors of Krystal Biotech?

Krystal Biotech's top institutional shareholders include:
  1. Vanguard Group Inc. — 9.63%
  2. Avoro Capital Advisors LLC — 9.58%
  3. Capital World Investors — 2.79%
  4. Dimensional Fund Advisors LP — 1.84%
  5. Braidwell LP — 1.79%
  6. First Trust Advisors LP — 0.86%
Learn More about top institutional investors of Krystal Biotech stock.

Which major investors are selling Krystal Biotech stock?

Within the previous quarter, KRYS stock was sold by these institutional investors:
  1. Braidwell LP
  2. Capital World Investors
  3. Readystate Asset Management LP
  4. Segall Bryant & Hamill LLC
  5. Aberdeen Group plc
  6. Decheng Capital LLC
  7. UBS AM A Distinct Business Unit of UBS Asset Management Americas LLC
  8. Vanguard Group Inc.
During the previous year, company insiders that have sold Krystal Biotech company stock include:
  1. Suma Krishnan (Insider)
  2. Kathryn Romano (CAO)
Learn More investors selling Krystal Biotech stock.

Which major investors are buying Krystal Biotech stock?

During the last quarter, KRYS stock was purchased by institutional investors including:
  1. Millennium Management LLC
  2. Avoro Capital Advisors LLC
  3. Orbimed Advisors LLC
  4. William Blair Investment Management LLC
  5. Voya Investment Management LLC
  6. Dimensional Fund Advisors LP
  7. Sig Brokerage LP
  8. First Trust Advisors LP