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KRYS Insider Trading

Insider Ownership Percentage: 13.70%
Insider Buying (Last 12 Months): $0.00
Insider Selling (Last 12 Months): $47,530,521.11

Krystal Biotech Insider Trading History Chart

This chart shows the insider buying and selling history at Krystal Biotech by year and by quarter.

Skip ChartChart Data in Insider Trading History Table

Krystal Biotech Share Price & Price History

Current Price: $251.68
Price Change: ▼ Price Decrease of -6.32 (-2.45%)
As of 03/20/2026 05:00 PM ET

This chart shows the closing price history over time for KRYS up to the past year.

Skip Chart and Table DataPrice Data in Insider Trading History Table
Days: 30 | 90 | 365

Krystal Biotech Insider Trading History

Transaction DateInsider NameTitleBuy/SellNumber of SharesAverage Share PriceTotal TransactionShares Held After TransactionDetails
3/4/2026Suma KrishnanInsiderSell25,000$263.21$6,580,250.001,403,155View SEC Filing Icon  
3/2/2026Kathryn RomanoCAOSell750$267.60$200,700.0022,366View SEC Filing Icon  
2/27/2026Daniel JanneyDirectorSell11,803$275.59$3,252,788.7773,293View SEC Filing Icon  
2/26/2026Daniel JanneyDirectorSell7,741$275.63$2,133,651.8385,096View SEC Filing Icon  
2/25/2026Daniel JanneyDirectorSell700$275.00$192,500.0092,837View SEC Filing Icon  
2/24/2026Daniel JanneyDirectorSell37,895$266.88$10,113,417.60View SEC Filing Icon  
2/24/2026Daniel JanneyDirectorSell13,825$268.34$3,709,800.5093,537View SEC Filing Icon  
2/19/2026Dino A. RossiDirectorSell18,950$261.41$4,953,719.5078,691View SEC Filing Icon  
2/9/2026Kathryn RomanoCAOSell12,500$272.14$3,401,750.0019,318View SEC Filing Icon  
12/4/2025Suma KrishnanInsiderSell25,000$220.16$5,504,000.001,413,711View SEC Filing Icon  
7/16/2025Suma KrishnanInsiderSell1,529$150.00$229,350.001,438,711View SEC Filing Icon  
7/16/2025Suma KrishnanInsiderSell1,389$150.00$208,350.001,508,056View SEC Filing Icon  
7/15/2025Suma KrishnanInsiderSell3,036$150.98$458,375.281,440,240View SEC Filing Icon  
7/15/2025Suma KrishnanInsiderSell3,084$151.01$465,714.841,509,445View SEC Filing Icon  
7/14/2025Suma KrishnanInsiderSell13,435$150.30$2,019,280.501,443,276View SEC Filing Icon  
7/14/2025Suma KrishnanInsiderSell13,400$150.30$2,014,020.001,512,529View SEC Filing Icon  
7/10/2025Suma KrishnanInsiderSell6,800$150.28$1,021,904.001,456,711View SEC Filing Icon  
7/10/2025Suma KrishnanInsiderSell6,927$150.27$1,040,920.291,525,929View SEC Filing Icon  
7/9/2025Suma KrishnanInsiderSell200$150.14$30,028.001,463,511View SEC Filing Icon  
3/13/2025Suma KrishnanInsiderSell25,000$177.79$4,444,750.001,463,711View SEC Filing Icon  
2/27/2025Kathryn RomanoCAOSell750$175.22$131,415.0012,604View SEC Filing Icon  
12/13/2024Suma KrishnanInsiderSell25,000$164.78$4,119,500.001,475,882View SEC Filing Icon  
9/12/2024Suma KrishnanInsiderSell25,000$197.76$4,944,000.001,500,882View SEC Filing Icon  
6/11/2024Suma KrishnanInsiderSell25,000$175.76$4,394,000.001,525,882View SEC Filing Icon  
5/20/2024Julian S. GangolliDirectorSell20,000$164.13$3,282,600.00View SEC Filing Icon  
3/11/2024Suma KrishnanInsiderSell25,000$170.96$4,274,000.001,550,882View SEC Filing Icon  
2/28/2024Kathryn RomanoCAOSell5,000$165.88$829,400.0012,936View SEC Filing Icon  
2/26/2024Kathryn RomanoCAOSell8,087$136.91$1,107,191.1712,556View SEC Filing Icon  
1/22/2024Kathryn RomanoCAOSell2,500$130.00$325,000.0012,556View SEC Filing Icon  
12/11/2023Suma KrishnanInsiderSell25,000$105.67$2,641,750.001,574,206View SEC Filing Icon  
9/11/2023Suma KrishnanInsiderSell25,000$127.23$3,180,750.001,599,206View SEC Filing Icon  
6/9/2023Andrew C OrthInsiderSell12,500$128.61$1,607,625.00100View SEC Filing Icon  
6/8/2023Daniel JanneyDirectorSell31,065$128.11$3,979,737.15126,297View SEC Filing Icon  
5/31/2023Suma KrishnanInsiderSell25,000$116.16$2,904,000.001,624,206View SEC Filing Icon  
5/22/2023Kathryn RomanoCAOSell25,000$109.04$2,726,000.0012,556View SEC Filing Icon  
5/19/2023Daniel JanneyDirectorSell50,000$95.02$4,751,000.00157,362View SEC Filing Icon  
5/19/2023Kathryn RomanoCAOSell28,428$95.05$2,702,081.4012,556View SEC Filing Icon  
5/9/2023Daniel JanneyDirectorSell17,100$90.74$1,551,654.00207,362View SEC Filing Icon  
4/19/2023Daniel JanneyDirectorSell7,900$90.32$713,528.00224,462View SEC Filing Icon  
4/17/2023Suma KrishnanInsiderSell25,000$87.65$2,191,250.001,649,206View SEC Filing Icon  
See Full Table

SEC Filings (Institutional Ownership Changes) for Krystal Biotech (NASDAQ:KRYS)

86.29% of Krystal Biotech stock is owned by institutions. Institutional ownership can be a sign of analyst confidence in the fundamentals of the stock.

Institutional Buying and Selling by Quarter

This chart shows the instiutional buying and selling at KRYS by year and by quarter.

Skip Institutional Buying and Selling Chart and Table DataRead Chart Data in Institutional Trading History Table

Krystal Biotech Institutional Trading History

Reporting DateHedge FundShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
3/9/2026Corient Private Wealth LLC38,346$9.50M0.0%-2.0%0.131%Search for SEC Filing on Google Icon
2/26/2026Seven Fleet Capital Management LP4,000$0.99M0.7%N/A0.014%Search for SEC Filing on Google Icon
2/24/2026Pacer Advisors Inc.1,712$0.42M0.0%+182.0%0.006%Search for SEC Filing on Google Icon
2/19/2026Invesco Ltd.60,008$14.79M0.0%-10.3%0.207%Search for SEC Filing on Google Icon
2/19/2026Corient Private Wealth LLC38,290$9.50M0.0%-2.1%0.132%Search for SEC Filing on Google Icon
2/18/2026Vident Advisory LLC1,494$0.37M0.0%+5.4%0.005%Search for SEC Filing on Google Icon
2/18/2026State of Tennessee Department of Treasury10,193$2.51M0.0%-8.3%0.035%Search for SEC Filing on Google Icon
2/18/2026EP Wealth Advisors LLC1,846$0.46M0.0%N/A0.006%Search for SEC Filing on Google Icon
2/18/2026Mackenzie Financial Corp1,554$0.38M0.0%-2.7%0.005%Search for SEC Filing on Google Icon
2/18/2026Empowered Funds LLC858$0.21M0.0%N/A0.003%Search for SEC Filing on Google Icon
2/18/2026Ikarian Capital LLC14,814$3.65M0.3%-39.3%0.051%Search for SEC Filing on Google Icon
2/18/2026Virtus Investment Advisers LLC2,792$0.69M0.2%-11.8%0.010%Search for SEC Filing on Google Icon
2/18/2026Wellington Management Group LLP10,651$2.63M0.0%-2.1%0.037%Search for SEC Filing on Google Icon
2/18/2026Susquehanna Portfolio Strategies LLC4,104$1.01M0.0%+8.6%0.014%Search for SEC Filing on Google Icon
2/18/2026Tudor Investment Corp ET AL1,375$0.34M0.0%N/A0.005%Search for SEC Filing on Google Icon
2/18/2026Orbimed Advisors LLC119,800$29.54M0.6%+16.6%0.413%Search for SEC Filing on Google Icon
2/18/2026Odyssean LLC3,014$0.74M0.5%N/A0.010%Search for SEC Filing on Google Icon
2/18/2026Perceptive Advisors LLC17,500$4.31M0.1%-50.0%0.060%Search for SEC Filing on Google Icon
2/18/2026Millennium Management LLC14,658$3.61M0.0%-90.1%0.051%Search for SEC Filing on Google Icon
2/18/2026Janus Henderson Group PLC219,440$54.15M0.0%+2,078.9%0.757%Search for SEC Filing on Google Icon
2/18/2026Elmind Capital LP22,000$5.42M1.6%N/A0.076%Search for SEC Filing on Google Icon
2/18/2026Clough Capital Partners L P7,806$1.92M0.2%N/A0.027%Search for SEC Filing on Google Icon
2/18/2026Boothbay Fund Management LLC3,527$0.87M0.0%-60.3%0.012%Search for SEC Filing on Google Icon
2/18/2026ACT Capital Management LLC60,500$14.92M12.1%N/A0.209%Search for SEC Filing on Google Icon
2/17/2026Guggenheim Capital LLC7,252$1.79M0.0%+79.0%0.025%Search for SEC Filing on Google Icon
2/17/2026ADAR1 Capital Management LLC20,014$4.93M0.4%+8.0%0.069%Search for SEC Filing on Google Icon
2/17/2026AQR Capital Management LLC14,157$3.49M0.0%-29.7%0.049%Search for SEC Filing on Google Icon
2/17/2026Braidwell LP202,101$49.83M1.6%-61.2%0.697%Search for SEC Filing on Google Icon
2/17/2026EFG International AG23,569$5.82M0.1%N/A0.081%Search for SEC Filing on Google Icon
2/17/2026Cetera Investment Advisers4,616$1.14M0.0%+2.6%0.016%Search for SEC Filing on Google Icon
2/17/2026Lazard Asset Management LLC1,058$0.26M0.0%N/A0.004%Search for SEC Filing on Google Icon
2/17/2026Amundi3,754$0.93M0.0%-17.7%0.013%Search for SEC Filing on Google Icon
2/17/2026Price T Rowe Associates Inc. MD529,955$130.66M0.0%+13.5%1.827%Search for SEC Filing on Google Icon
2/17/2026Regal Investment Advisors LLC4,360$1.08M0.1%+1.0%0.015%Search for SEC Filing on Google Icon
2/17/2026Osaic Holdings Inc.6,732$1.66M0.0%+1,635.1%0.023%Search for SEC Filing on Google Icon
2/17/2026California State Teachers Retirement System20,583$5.08M0.0%-1.4%0.071%Search for SEC Filing on Google Icon
2/17/2026Russell Investments Group Ltd.28,954$7.14M0.0%+9.1%0.100%Search for SEC Filing on Google Icon
2/17/2026Maryland State Retirement & Pension System3,774$0.93M0.0%+1.9%0.013%Search for SEC Filing on Google Icon
2/17/2026State of Wisconsin Investment Board14,466$3.57M0.0%-50.7%0.050%Search for SEC Filing on Google Icon
2/17/2026Captrust Financial Advisors1,175$0.29M0.0%N/A0.004%Search for SEC Filing on Google Icon
2/17/2026Avoro Capital Advisors LLC2,888,888$712.23M6.8%+4.0%9.883%Search for SEC Filing on Google Icon
2/17/2026Royal Bank of Canada1,501$0.37M0.0%+277.1%0.005%Search for SEC Filing on Google Icon
2/17/2026Blair William & Co. IL3,177$0.78M0.0%-33.1%0.011%Search for SEC Filing on Google Icon
2/17/2026Cynosure Group LLC2,406$0.59M0.0%-59.3%0.008%Search for SEC Filing on Google Icon
2/16/2026Vanguard Personalized Indexing Management LLC2,127$0.52M0.0%+5.8%0.007%Search for SEC Filing on Google Icon
2/16/2026Verition Fund Management LLC16,969$4.18M0.0%-45.8%0.059%Search for SEC Filing on Google Icon
2/16/2026S Squared Technology LLC96,215$23.72M9.2%-11.9%0.332%Search for SEC Filing on Google Icon
2/16/2026Mariner LLC4,320$1.07M0.0%-6.2%0.015%Search for SEC Filing on Google Icon
2/16/2026NFJ Investment Group LLC8,249$2.03M0.1%-4.2%0.028%Search for SEC Filing on Google Icon
2/16/2026Frazier Life Sciences Management L.P.488,460$120.43M3.2%-29.1%1.684%Search for SEC Filing on Google Icon
2/16/2026Kennedy Capital Management LLC4,501$1.11M0.0%-88.5%0.016%Search for SEC Filing on Google Icon
2/16/2026Entropy Technologies LP2,503$0.62M0.0%N/A0.009%Search for SEC Filing on Google Icon
2/16/2026Barclays PLC60,062$14.81M0.0%-20.9%0.207%Search for SEC Filing on Google Icon
2/16/2026Biondo Investment Advisors LLC68,130$16.80M2.0%+31.3%0.235%Search for SEC Filing on Google Icon
2/16/2026Bridge City Capital LLC12,135$2.99M0.9%-14.3%0.042%Search for SEC Filing on Google Icon
2/13/2026FORA Capital LLC2,112$0.52M0.1%N/A0.007%Search for SEC Filing on Google Icon
2/13/2026Marshall Wace LLP183,754$45.30M0.0%+42.5%0.634%Search for SEC Filing on Google Icon
2/13/2026The Manufacturers Life Insurance Company 40,629$10.06M0.0%+17.9%0.140%Search for SEC Filing on Google Icon
2/13/2026CANADA LIFE ASSURANCE Co22,087$5.45M0.0%+3.2%0.076%Search for SEC Filing on Google Icon
2/13/2026Segall Bryant & Hamill LLC83,246$20.52M0.3%-2.4%0.287%Search for SEC Filing on Google Icon
2/13/2026Bridgewater Associates LP10,015$2.47M0.0%+3.0%0.035%Search for SEC Filing on Google Icon
2/13/2026UMB Bank n.a.144$36K0.0%+34.6%0.000%Search for SEC Filing on Google Icon
2/13/2026Smartleaf Asset Management LLC610$0.15M0.0%+44.5%0.002%Search for SEC Filing on Google Icon
2/13/2026Greenline Wealth Management LLC136$34K0.0%N/A0.000%Search for SEC Filing on Google Icon
2/13/2026Morgan Stanley221,481$54.61M0.0%-5.6%0.764%Search for SEC Filing on Google Icon
2/13/2026Public Sector Pension Investment Board89,362$22.03M0.1%-11.0%0.308%Search for SEC Filing on Google Icon
2/13/2026Rafferty Asset Management LLC24,268$5.98M0.0%-29.9%0.084%Search for SEC Filing on Google Icon
2/13/2026First Trust Advisors LP245,276$60.47M0.0%-1.3%0.846%Search for SEC Filing on Google Icon
2/13/2026Charles Schwab Investment Management Inc.242,774$59.85M0.0%0.0%0.837%Search for SEC Filing on Google Icon
2/13/2026Police & Firemen s Retirement System of New Jersey6,747$1.66M0.0%-1.6%0.023%Search for SEC Filing on Google Icon
2/13/2026State Street Corp1,342,303$330.93M0.0%-3.8%4.629%Search for SEC Filing on Google Icon
2/13/2026Vontobel Holding Ltd.2,155$0.53M0.0%-43.0%0.007%Search for SEC Filing on Google Icon
2/13/2026UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC33,617$8.29M0.0%-83.4%0.116%Search for SEC Filing on Google Icon
2/13/2026Wells Fargo & Company MN31,572$7.78M0.0%+60.6%0.109%Search for SEC Filing on Google Icon
2/13/2026Rhenman & Partners Asset Management AB25,000$6.16M0.6%+112.8%0.086%Search for SEC Filing on Google Icon
2/13/2026Castleark Management LLC29,260$7.21M0.2%N/A0.101%Search for SEC Filing on Google Icon
2/12/2026Soleus Capital Management L.P.941,059$232.01M8.6%-7.6%3.245%Search for SEC Filing on Google Icon
2/12/2026Orion Porfolio Solutions LLC927$0.23M0.0%N/A0.003%Search for SEC Filing on Google Icon
2/12/2026MetLife Investment Management LLC13,844$3.41M0.0%-4.1%0.048%Search for SEC Filing on Google Icon
2/12/2026Cibc World Markets Corp1,640$0.40M0.0%N/A0.006%Search for SEC Filing on Google Icon
2/12/2026Commonwealth Equity Services LLC9,887$2.44M0.0%-1.2%0.034%Search for SEC Filing on Google Icon
2/12/2026State Board of Administration of Florida Retirement System15,756$3.88M0.0%+172.4%0.054%Search for SEC Filing on Google Icon
2/12/2026Renaissance Technologies LLC3,300$0.81M0.0%N/A0.011%Search for SEC Filing on Google Icon
2/12/2026Dimensional Fund Advisors LP492,968$121.54M0.0%-7.7%1.700%Search for SEC Filing on Google Icon
2/12/2026Federated Hermes Inc.34,541$8.52M0.0%+44.0%0.119%Search for SEC Filing on Google Icon
2/12/2026Decheng Capital LLC17,300$4.27M0.6%-46.4%0.060%Search for SEC Filing on Google Icon
2/12/2026Mindset Wealth Management LLC1,793$0.44M0.1%+22.0%0.006%Search for SEC Filing on Google Icon
2/12/2026Ensign Peak Advisors Inc1,369$0.34M0.0%-69.0%0.005%Search for SEC Filing on Google Icon
2/12/2026AlphaCentric Advisors LLC1,813$0.45M0.4%N/A0.006%Search for SEC Filing on Google Icon
2/12/2026Informed Momentum Co LLC24,667$6.08M0.7%N/A0.085%Search for SEC Filing on Google Icon
2/12/2026Skandinaviska Enskilda Banken AB publ 46,732$11.52M0.0%-22.1%0.161%Search for SEC Filing on Google Icon
2/12/2026New York State Common Retirement Fund31,342$7.73M0.0%+16.1%0.108%Search for SEC Filing on Google Icon
2/12/2026Granite Investment Partners LLC25,760$6.35M0.4%N/A0.089%Search for SEC Filing on Google Icon
2/12/2026Bank of Montreal Can2,231$0.55M0.0%-4.2%0.008%Search for SEC Filing on Google Icon
2/12/2026Swiss National Bank42,900$10.58M0.0%+2.1%0.148%Search for SEC Filing on Google Icon
2/12/2026Aviva PLC2,228$0.55M0.0%-31.0%0.008%Search for SEC Filing on Google Icon
2/12/2026Nuveen LLC189,094$46.62M0.0%-4.2%0.652%Search for SEC Filing on Google Icon
2/11/2026Vestor Capital LLC2,940$0.73M0.0%N/A0.010%Search for SEC Filing on Google Icon
2/11/2026Empowered Funds LLC858$0.21M0.0%N/A0.003%Search for SEC Filing on Google Icon
2/11/2026Janney Montgomery Scott LLC2,398$0.59M0.0%-7.1%0.008%Search for SEC Filing on Google Icon
Data available starting January 2016

See Full Table
Krystal Biotech logo
Krystal Biotech, Inc., a commercial-stage biotechnology company, discovers, develops, and commercializes genetic medicines for patients with rare diseases in the United States. It commercializes VYJUVEK (beremagene geperpavec-svdt, or B-VEC) for the treatment of dystrophic epidermolysis bullosa (DEB). The company also develops KB105, which is in Phase 1/2 clinical trials for treating patients with deficient autosomal recessive congenital ichthyosis; KB104 for treating netherton syndrome; KB407 that is in Phase 1 clinical trials for treating cystic fibrosis; KB707 that is in Phase 1 clinical trials for the treatment of anti-PD-1 relapsed/refractory; KB408, which is in Phase 1 clinical trials for treating Alpha-1 antitrypsin deficiency; and KB301 that is in Phase 2 clinical trials for treating aesthetic skin conditions, as well as in open label study with ophthalmic B-VEC for treating for ocular complications of deb. Krystal Biotech, Inc. was founded in 2016 and is headquartered in Pittsburgh, Pennsylvania.
Read More on Krystal Biotech

Today's Range

Now: $251.68
Low: $249.38
High: $263.75

50 Day Range

MA: $270.82
Low: $247.26
High: $291.93

52 Week Range

Now: $251.68
Low: $122.80
High: $298.30

Volume

839,966 shs

Average Volume

246,166 shs

Market Capitalization

$7.36 billion

P/E Ratio

36.74

Dividend Yield

N/A

Beta

0.49

Who are the company insiders with the largest holdings of Krystal Biotech?

Krystal Biotech's top insider investors include:
  1. Suma Krishnan (Insider)
  2. Daniel Janney (Director)
  3. Dino A Rossi (Director)
  4. Kathryn Romano (CAO)
  5. Julian S Gangolli (Director)
Learn More about top insider investors at Krystal Biotech.

Who are the major institutional investors of Krystal Biotech?

Krystal Biotech's top institutional shareholders include:
  1. Avoro Capital Advisors LLC — 9.88%
  2. Vanguard Group Inc. — 9.58%
  3. State Street Corp — 4.63%
  4. Soleus Capital Management L.P. — 3.25%
  5. Capital World Investors — 2.79%
  6. Geode Capital Management LLC — 2.11%
Learn More about top institutional investors of Krystal Biotech stock.

Which major investors are selling Krystal Biotech stock?

Within the previous quarter, KRYS stock was sold by these institutional investors:
  1. Braidwell LP
  2. Nantahala Capital Management LLC
  3. Frazier Life Sciences Management L.P.
  4. UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC
  5. Millennium Management LLC
  6. Soleus Capital Management L.P.
  7. Goldman Sachs Group Inc.
  8. State Street Corp
During the previous year, company insiders that have sold Krystal Biotech company stock include:
  1. Suma Krishnan (Insider)
  2. Daniel Janney (Director)
  3. Dino A Rossi (Director)
  4. Kathryn Romano (CAO)
Learn More investors selling Krystal Biotech stock.

Which major investors are buying Krystal Biotech stock?

During the last quarter, KRYS stock was purchased by institutional investors including:
  1. Norges Bank
  2. William Blair Investment Management LLC
  3. Janus Henderson Group PLC
  4. UBS Group AG
  5. Avoro Capital Advisors LLC
  6. Franklin Resources Inc.
  7. Price T Rowe Associates Inc. MD
  8. ACT Capital Management LLC