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LXRX Insider Trading

Insider Ownership Percentage: 13.90%
Insider Buying (Last 12 Months): $2,369,980.60
Insider Selling (Last 12 Months): $0.00

Lexicon Pharmaceuticals Insider Trading History Chart

This chart shows the insider buying and selling history at Lexicon Pharmaceuticals by year and by quarter.

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Lexicon Pharmaceuticals Share Price & Price History

Current Price: $1.56
Price Change: ▼ Price Decrease of -0.06 (-3.70%)
As of 03/20/2026 05:00 PM ET

This chart shows the closing price history over time for LXRX up to the past year.

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Days: 30 | 90 | 365

Lexicon Pharmaceuticals Insider Trading History

Transaction DateInsider NameTitleBuy/SellNumber of SharesAverage Share PriceTotal TransactionShares Held After TransactionDetails
2/25/2026Raymond DebbaneDirectorBuy2,000$1.49$2,980.001,906,186View SEC Filing Icon  
2/23/2026Raymond DebbaneDirectorBuy100,000$1.47$147,000.001,904,186View SEC Filing Icon  
2/20/2026Raymond DebbaneDirectorBuy100,000$1.48$148,000.001,804,186View SEC Filing Icon  
2/19/2026Raymond DebbaneDirectorBuy50,000$1.44$72,000.001,704,186View SEC Filing Icon  
2/2/2026Invus Global Management, LlcDirectorBuy1,538,462$1.30$2,000,000.601,538,462View SEC Filing Icon  
11/16/2023Lonnel CoatsCEOBuy90,000$1.05$94,500.00914,359View SEC Filing Icon  
11/10/2023Lonnel CoatsCEOBuy10,000$1.01$10,100.00824,359View SEC Filing Icon  
10/12/2023Raymond DebbaneDirectorBuy148,820$1.03$153,284.601,340,847View SEC Filing Icon  
10/10/2023Raymond DebbaneDirectorBuy508,306$1.14$579,468.84849,153View SEC Filing Icon  
9/14/2023Jeffrey L WadeCFOBuy10,000$1.38$13,800.00264,341View SEC Filing Icon  
8/4/2023Wendy McDermottVPBuy6,000$1.84$11,040.0028,478View SEC Filing Icon  
6/29/2023Lonnel CoatsCEOBuy10,000$2.16$21,600.00814,359View SEC Filing Icon  
6/26/2023Lonnel CoatsCEOBuy10,000$2.18$21,800.00804,359View SEC Filing Icon  
6/23/2023Wendy McDermottVPBuy10,000$2.43$24,300.0022,478View SEC Filing Icon  
6/22/2023Lonnel CoatsCEOBuy40,000$2.31$92,400.00784,359View SEC Filing Icon  
6/20/2023Jeffrey L WadeCFOBuy12,000$2.33$27,960.00254,341View SEC Filing Icon  
6/5/2023International S.C.A. ArtalDirectorBuy27,775,050$2.60$72,215,130.0078,634,381View SEC Filing Icon  
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SEC Filings (Institutional Ownership Changes) for Lexicon Pharmaceuticals (NASDAQ:LXRX)

74.70% of Lexicon Pharmaceuticals stock is owned by institutions. Institutional ownership can be a sign of analyst confidence in the fundamentals of the stock.

Institutional Buying and Selling by Quarter

This chart shows the instiutional buying and selling at LXRX by year and by quarter.

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Lexicon Pharmaceuticals Institutional Trading History

Reporting DateHedge FundShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
2/23/2026Virtu Financial LLC36,468$42K0.0%N/A0.010%Search for SEC Filing on Google Icon
2/19/2026Invesco Ltd.594,883$0.68M0.0%+14.1%0.164%Search for SEC Filing on Google Icon
2/18/2026XTX Topco Ltd96,090$0.11M0.0%-70.8%0.026%Search for SEC Filing on Google Icon
2/18/2026Ikarian Capital LLC164,674$0.19M0.0%-6.7%0.045%Search for SEC Filing on Google Icon
2/18/2026Millennium Management LLC4,821,733$5.55M0.0%+25.9%1.327%Search for SEC Filing on Google Icon
2/18/2026Ishara Investments LP880,000$1.01M1.2%N/A0.242%Search for SEC Filing on Google Icon
2/18/2026Boothbay Fund Management LLC44,315$51K0.0%-21.0%0.012%Search for SEC Filing on Google Icon
2/17/2026AQR Capital Management LLC144,800$0.17M0.0%-52.2%0.040%Search for SEC Filing on Google Icon
2/17/2026ExodusPoint Capital Management LP268,433$0.31M0.0%N/A0.074%Search for SEC Filing on Google Icon
2/17/2026Graham Capital Management L.P.109,900$0.13M0.0%N/A0.030%Search for SEC Filing on Google Icon
2/16/2026OMERS ADMINISTRATION Corp273,800$0.32M0.0%N/A0.075%Search for SEC Filing on Google Icon
2/16/2026Barclays PLC194,743$0.22M0.0%+511.2%0.054%Search for SEC Filing on Google Icon
2/13/2026Security National Bank of Sioux City Iowa IA26,650$31K0.0%N/A0.007%Search for SEC Filing on Google Icon
2/13/2026Marshall Wace LLP1,262,367$1.45M0.0%N/A0.347%Search for SEC Filing on Google Icon
2/13/2026Hudson Bay Capital Management LP100,532$0.12M0.0%N/A0.028%Search for SEC Filing on Google Icon
2/13/2026Quarry LP88,000$0.10M0.0%N/A0.024%Search for SEC Filing on Google Icon
2/13/2026Headlands Technologies LLC136,113$0.16M0.0%+174.2%0.037%Search for SEC Filing on Google Icon
2/13/2026Charles Schwab Investment Management Inc.1,055,123$1.21M0.0%-7.8%0.290%Search for SEC Filing on Google Icon
2/12/2026HRT Financial LP117,549$0.14M0.0%+153.1%0.032%Search for SEC Filing on Google Icon
2/12/2026Renaissance Technologies LLC263,254$0.30M0.0%-10.0%0.072%Search for SEC Filing on Google Icon
2/12/2026EntryPoint Capital LLC33,618$39K0.0%N/A0.009%Search for SEC Filing on Google Icon
2/12/2026CIBC Private Wealth Group LLC1,950,000$2.24M0.0%-18.8%0.536%Search for SEC Filing on Google Icon
2/11/2026Cerity Partners LLC144,944$0.17M0.0%-8.3%0.040%Search for SEC Filing on Google Icon
2/11/2026State of Wyoming60,571$70K0.0%+610.4%0.017%Search for SEC Filing on Google Icon
2/10/2026CIBC Asset Management Inc39,520$45K0.0%N/A0.011%Search for SEC Filing on Google Icon
2/10/2026Goldman Sachs Group Inc.921,204$1.06M0.0%+1,452.2%0.253%Search for SEC Filing on Google Icon
2/10/2026Monaco Asset Management SAM117,188$0.14M0.0%-66.5%0.032%Search for SEC Filing on Google Icon
2/9/2026Geode Capital Management LLC2,500,022$2.88M0.0%+4.3%0.688%Search for SEC Filing on Google Icon
2/6/2026Leonteq Securities AG30,000$34K0.0%N/A0.008%Search for SEC Filing on Google Icon
2/6/2026GSA Capital Partners LLP996,235$1.15M0.1%-17.2%0.274%Search for SEC Filing on Google Icon
2/5/2026Pinnacle Associates Ltd.29,015$33K0.0%-42.9%0.008%Search for SEC Filing on Google Icon
1/30/2026R Squared Ltd46,579$54K0.0%+45.3%0.013%Search for SEC Filing on Google Icon
1/29/2026UBS Group AG3,007,237$3.46M0.0%+752.1%0.828%Search for SEC Filing on Google Icon
1/14/2026Hennion & Walsh Asset Management Inc.901,222$1.04M0.0%+15.7%0.248%Search for SEC Filing on Google Icon
11/26/2025Vermillion & White Wealth Management Group LLC32,500$44K0.0%+400.0%0.009%Search for SEC Filing on Google Icon
11/24/2025CIBC Private Wealth Group LLC2,400,257$3.24M0.0%-2.0%0.661%Search for SEC Filing on Google Icon
11/21/2025CIBC Bancorp USA Inc.2,400,257$3.24M0.0%N/A0.661%Search for SEC Filing on Google Icon
11/17/2025Jacobs Levy Equity Management Inc.692,727$0.94M0.0%N/A0.191%Search for SEC Filing on Google Icon
11/17/2025Scientech Research LLC24,884$34K0.0%-57.0%0.007%Search for SEC Filing on Google Icon
11/17/2025Millennium Management LLC3,830,660$5.17M0.0%+133.1%1.054%Search for SEC Filing on Google Icon
11/17/2025Bank of America Corp DE57,804$78K0.0%+80.1%0.016%Search for SEC Filing on Google Icon
11/14/2025Schonfeld Strategic Advisors LLC825,633$1.12M0.0%-82.0%0.227%Search for SEC Filing on Google Icon
11/14/2025Two Sigma Investments LP559,008$0.76M0.0%+38.4%0.154%Search for SEC Filing on Google Icon
11/14/2025Squarepoint Ops LLC58,676$79K0.0%-38.6%0.016%Search for SEC Filing on Google Icon
11/13/2025Jefferies Financial Group Inc.97,400$0.13M0.0%N/A0.027%Search for SEC Filing on Google Icon
11/10/2025Optiver Holding B.V.75,893$0.10M0.0%+2,400.6%0.021%Search for SEC Filing on Google Icon
11/10/2025Monaco Asset Management SAM350,000$0.47M0.0%-34.2%0.096%Search for SEC Filing on Google Icon
11/10/2025China Universal Asset Management Co. Ltd.63,698$86K0.0%-12.7%0.018%Search for SEC Filing on Google Icon
11/7/2025GSA Capital Partners LLP1,202,906$1.62M0.1%-57.5%0.331%Search for SEC Filing on Google Icon
11/7/2025Vanguard Group Inc.9,521,874$12.86M0.0%+7.6%2.620%Search for SEC Filing on Google Icon
11/6/2025Compagnie Lombard Odier SCmA410,000$0.55M0.0%+24.2%0.113%Search for SEC Filing on Google Icon
10/29/2025Wealth Enhancement Advisory Services LLC18,877$25K0.0%-74.6%0.005%Search for SEC Filing on Google Icon
10/22/2025Hennion & Walsh Asset Management Inc.779,212$1.05M0.0%-1.8%0.214%Search for SEC Filing on Google Icon
10/15/2025CWM LLC26,744$36K0.0%-75.5%0.007%Search for SEC Filing on Google Icon
8/18/2025Hudson Bay Capital Management LP27,010$26K0.0%N/A0.007%Search for SEC Filing on Google Icon
8/15/2025Hudson Bay Capital Management LP27,010$26K0.0%N/A0.007%Search for SEC Filing on Google Icon
8/15/2025Boothbay Fund Management LLC56,120$53K0.0%-87.7%0.015%Search for SEC Filing on Google Icon
8/15/2025Bank of America Corp DE32,097$30K0.0%-66.7%0.009%Search for SEC Filing on Google Icon
8/14/2025Cerity Partners LLC206,279$0.20M0.0%+21.1%0.057%Search for SEC Filing on Google Icon
8/13/2025Invesco Ltd.420,700$0.40M0.0%+47.2%0.116%Search for SEC Filing on Google Icon
8/12/2025XTX Topco Ltd66,276$63K0.0%+431.4%0.018%Search for SEC Filing on Google Icon
8/12/2025Catalyst Funds Management Pty Ltd53,700$51K0.0%N/A0.015%Search for SEC Filing on Google Icon
8/8/2025Geode Capital Management LLC2,377,694$2.25M0.0%-35.6%0.658%Search for SEC Filing on Google Icon
8/7/2025Monaco Asset Management SAM531,600$0.50M0.1%-27.6%0.147%Search for SEC Filing on Google Icon
8/6/2025Savant Capital LLC69,578$66K0.0%+33.2%0.019%Search for SEC Filing on Google Icon
7/31/2025R Squared Ltd29,559$28K0.0%N/A0.008%Search for SEC Filing on Google Icon
7/25/2025Vanguard Personalized Indexing Management LLC65,330$62K0.0%+77.8%0.018%Search for SEC Filing on Google Icon
7/15/2025Compagnie Lombard Odier SCmA330,000$0.31M0.0%+200.0%0.091%Search for SEC Filing on Google Icon
6/27/2025Goldman Sachs Group Inc.355,152$0.16M0.0%-34.3%0.098%Search for SEC Filing on Google Icon
5/29/2025Rhumbline Advisers137,230$63K0.0%-10.4%0.038%Search for SEC Filing on Google Icon
5/21/2025Acadian Asset Management LLC573,688$0.26M0.0%N/A0.159%Search for SEC Filing on Google Icon
5/16/2025Goldman Sachs Group Inc.355,152$0.16M0.0%-34.3%0.098%Search for SEC Filing on Google Icon
5/16/2025AQR Capital Management LLC1,173,225$0.54M0.0%N/A0.325%Search for SEC Filing on Google Icon
5/15/2025Nantahala Capital Management LLC460,850$0.21M0.0%-93.0%0.127%Search for SEC Filing on Google Icon
5/15/2025Siren L.L.C.3,516,214$1.62M0.1%-91.0%0.973%Search for SEC Filing on Google Icon
5/14/2025Ieq Capital LLC177,302$82K0.0%N/A0.049%Search for SEC Filing on Google Icon
5/12/2025Invesco Ltd.285,759$0.13M0.0%+173.5%0.079%Search for SEC Filing on Google Icon
5/9/2025Deutsche Bank AG94,394$43K0.0%-70.1%0.026%Search for SEC Filing on Google Icon
5/9/2025Charles Schwab Investment Management Inc.1,150,771$0.53M0.0%-3.4%0.318%Search for SEC Filing on Google Icon
5/8/2025Monaco Asset Management SAM734,148$0.34M0.1%N/A0.203%Search for SEC Filing on Google Icon
5/6/2025Pinnacle Associates Ltd.54,180$25K0.0%-96.2%0.015%Search for SEC Filing on Google Icon
5/1/2025CWM LLC105,504$49K0.0%+9,228.4%0.043%Search for SEC Filing on Google Icon
4/30/2025Cerity Partners LLC170,387$79K0.0%+76.5%0.069%Search for SEC Filing on Google Icon
4/28/2025Straight Path Wealth Management62,666$29K0.0%N/A0.025%Search for SEC Filing on Google Icon
4/16/2025Wealth Enhancement Advisory Services LLC69,207$32K0.0%N/A0.028%Search for SEC Filing on Google Icon
4/10/2025Hennion & Walsh Asset Management Inc.830,054$0.38M0.0%-3.8%0.337%Search for SEC Filing on Google Icon
3/18/2025California State Teachers Retirement System195,215$0.14M0.0%+29.9%0.079%Search for SEC Filing on Google Icon
2/17/2025UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC353,508$0.26M0.0%+193.6%0.144%Search for SEC Filing on Google Icon
2/17/2025Woodline Partners LP229,376$0.17M0.0%-81.1%0.093%Search for SEC Filing on Google Icon
2/17/2025Tang Capital Management LLC850,268$0.63M0.0%+750.3%0.345%Search for SEC Filing on Google Icon
2/17/2025Point72 Asset Management L.P.8,988,421$6.64M0.0%+630.7%3.650%Search for SEC Filing on Google Icon
2/17/2025Deutsche Bank AG315,659$0.23M0.0%+378.0%0.128%Search for SEC Filing on Google Icon
2/17/2025Bank of America Corp DE136,407$0.10M0.0%+27.4%0.055%Search for SEC Filing on Google Icon
2/17/2025Bayesian Capital Management LP42,000$31K0.0%N/A0.017%Search for SEC Filing on Google Icon
2/14/2025Jane Street Group LLC220,264$0.16M0.0%+158.0%0.089%Search for SEC Filing on Google Icon
2/14/2025Schonfeld Strategic Advisors LLC7,558,621$5.58M0.0%+301.5%3.070%Search for SEC Filing on Google Icon
2/14/2025Nantahala Capital Management LLC6,604,150$4.88M0.2%+186.6%2.682%Search for SEC Filing on Google Icon
2/14/2025Northern Trust Corp1,308,651$0.97M0.0%+14.4%0.531%Search for SEC Filing on Google Icon
2/14/2025Boothbay Fund Management LLC480,822$0.36M0.0%N/A0.195%Search for SEC Filing on Google Icon
2/14/2025Virtus ETF Advisers LLC425,269$0.31M0.1%+136.3%0.173%Search for SEC Filing on Google Icon
Data available starting January 2016

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Lexicon Pharmaceuticals logo
Lexicon Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of pharmaceutical products. Its orally-delivered small molecule drug candidates under development comprise Sotagliflozin that completed Phase III clinical trials for the for the treatment of heart failure and type 1 diabetes; and LX9211, which is in Phase II clinical development for the treatment of neuropathic pain and LX2761, which is in Phase I clinical development for gastrointestinal tract. Lexicon Pharmaceuticals, Inc. has strategic collaboration and license agreements with Bristol-Myers Squibb Company and Genentech, Inc. The company was incorporated in 1995 and is headquartered in The Woodlands, Texas.
Read More on Lexicon Pharmaceuticals

Today's Range

Now: $1.56
Low: $1.52
High: $1.62

50 Day Range

MA: $1.46
Low: $1.16
High: $1.76

52 Week Range

Now: $1.56
Low: $0.32
High: $1.83

Volume

6,680,326 shs

Average Volume

2,532,127 shs

Market Capitalization

$660.94 million

P/E Ratio

N/A

Dividend Yield

N/A

Beta

0.94

Who are the company insiders with the largest holdings of Lexicon Pharmaceuticals?

Lexicon Pharmaceuticals' top insider shareholders include:
  1. Raymond Debbane (Director)
  2. Invus Global Management, Llc (Director)
Learn More about top insider investors at Lexicon Pharmaceuticals.

Who are the major institutional investors of Lexicon Pharmaceuticals?

Lexicon Pharmaceuticals' top institutional investors include:
  1. Millennium Management LLC — 1.33%
  2. UBS Group AG — 0.83%
  3. Geode Capital Management LLC — 0.69%
  4. CIBC Private Wealth Group LLC — 0.54%
  5. Marshall Wace LLP — 0.35%
  6. Charles Schwab Investment Management Inc. — 0.29%
Learn More about top institutional investors of Lexicon Pharmaceuticals stock.

Which major investors are selling Lexicon Pharmaceuticals stock?

During the last quarter, LXRX stock was sold by these institutional investors:
  1. CIBC Private Wealth Group LLC
  2. XTX Topco Ltd
  3. Monaco Asset Management SAM
  4. GSA Capital Partners LLP
  5. AQR Capital Management LLC
  6. Charles Schwab Investment Management Inc.
  7. Simplex Trading LLC
  8. Renaissance Technologies LLC

Which major investors are buying Lexicon Pharmaceuticals stock?

In the previous quarter, LXRX stock was acquired by institutional investors including:
  1. UBS Group AG
  2. Marshall Wace LLP
  3. Millennium Management LLC
  4. Ishara Investments LP
  5. Goldman Sachs Group Inc.
  6. OMERS ADMINISTRATION Corp
  7. ExodusPoint Capital Management LP
  8. Barclays PLC
In the previous year, these company insiders have bought Lexicon Pharmaceuticals stock:
  1. Raymond Debbane (Director)
  2. Invus Global Management, Llc (Director)
Learn More investors buying Lexicon Pharmaceuticals stock.