| 11/17/2025 | Armistice Capital LLC | 507,650 | $19.25M | 0.3% | +185.2% | 0.641% |  |
| 11/17/2025 | Laurion Capital Management LP | 1,720,445 | $65.24M | 1.1% | -2.4% | 2.174% |  |
| 11/17/2025 | XTX Topco Ltd | 18,840 | $0.71M | 0.0% | N/A | 0.024% |  |
| 11/17/2025 | Zimmer Partners LP | 100,000 | $3.79M | 0.1% | -38.5% | 0.126% |  |
| 11/17/2025 | Velan Capital Investment Management LP | 175,600 | $6.66M | 6.3% | +0.6% | 0.222% |  |
| 11/17/2025 | Verition Fund Management LLC | 18,463 | $0.70M | 0.0% | N/A | 0.023% |  |
| 11/17/2025 | Scientech Research LLC | 7,964 | $0.30M | 0.1% | N/A | 0.010% |  |
| 11/17/2025 | Polar Capital Holdings Plc | 1,058,776 | $40.15M | 0.2% | N/A | 1.338% |  |
| 11/17/2025 | Qube Research & Technologies Ltd | 180,426 | $6.84M | 0.0% | -48.6% | 0.228% |  |
| 11/17/2025 | RA Capital Management L.P. | 7,323,750 | $277.72M | 3.4% | +19.1% | 9.254% |  |
| 11/17/2025 | Parkman Healthcare Partners LLC | 455,523 | $17.27M | 1.8% | -1.7% | 0.576% |  |
| 11/17/2025 | Nantahala Capital Management LLC | 158,713 | $6.02M | 0.2% | -55.2% | 0.201% |  |
| 11/17/2025 | Mariner LLC | 16,409 | $0.62M | 0.0% | -42.8% | 0.021% |  |
| 11/17/2025 | Millennium Management LLC | 404,589 | $15.34M | 0.0% | +66.1% | 0.511% |  |
| 11/17/2025 | MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 19,716 | $0.75M | 0.0% | -18.7% | 0.025% |  |
| 11/17/2025 | Moore Capital Management LP | 165,000 | $6.26M | 0.1% | N/A | 0.208% |  |
| 11/17/2025 | Jain Global LLC | 120,854 | $4.58M | 0.0% | N/A | 0.153% |  |
| 11/17/2025 | HighVista Strategies LLC | 209,829 | $7.96M | 1.9% | +39.8% | 0.265% |  |
| 11/17/2025 | Holocene Advisors LP | 1,205,377 | $45.71M | 0.1% | N/A | 1.523% |  |
| 11/17/2025 | Farallon Capital Management LLC | 1,673,053 | $63.44M | 0.3% | N/A | 2.114% |  |
| 11/17/2025 | Cinctive Capital Management LP | 71,713 | $2.72M | 0.1% | +345.1% | 0.091% |  |
| 11/17/2025 | Bank of America Corp DE | 768,265 | $29.13M | 0.0% | +191.7% | 0.971% |  |
| 11/17/2025 | Boothbay Fund Management LLC | 942,626 | $35.74M | 0.5% | +15.4% | 1.191% |  |
| 11/17/2025 | 22NW LP | 358,325 | $13.59M | 7.1% | -36.0% | 0.453% |  |
| 11/17/2025 | Algert Global LLC | 47,500 | $1.80M | 0.0% | N/A | 0.060% |  |
| 11/17/2025 | Alliancebernstein L.P. | 882,415 | $33.46M | 0.0% | +3,160.1% | 1.115% |  |
| 11/17/2025 | Ameriprise Financial Inc. | 97,147 | $3.68M | 0.0% | +91.0% | 0.123% |  |
| 11/14/2025 | Schonfeld Strategic Advisors LLC | 14,618 | $0.55M | 0.0% | -94.2% | 0.018% |  |
| 11/14/2025 | Creative Planning | 22,295 | $0.85M | 0.0% | -10.3% | 0.028% |  |
| 11/14/2025 | Bellevue Group AG | 26,605 | $1.01M | 0.0% | +71.0% | 0.034% |  |
| 11/14/2025 | Caligan Partners LP | 2,772,654 | $105.14M | 13.8% | +37.4% | 3.503% |  |
| 11/14/2025 | Burkehill Global Management LP | 150,000 | $5.69M | 0.3% | N/A | 0.190% |  |
| 11/14/2025 | Orbimed Advisors LLC | 1,469,494 | $55.72M | 1.4% | +93.3% | 1.857% |  |
| 11/14/2025 | ADAR1 Capital Management LLC | 78,238 | $2.97M | 0.3% | -74.1% | 0.099% |  |
| 11/14/2025 | Zurcher Kantonalbank Zurich Cantonalbank | 22,318 | $0.85M | 0.0% | -2.4% | 0.028% |  |
| 11/14/2025 | UBS AM A Distinct Business Unit of UBS Asset Management Americas LLC | 59,042 | $2.24M | 0.0% | +141.9% | 0.075% |  |
| 11/14/2025 | Squarepoint Ops LLC | 43,013 | $1.63M | 0.0% | +273.5% | 0.054% |  |
| 11/14/2025 | Integral Health Asset Management LLC | 1,500,000 | $56.88M | 3.8% | -44.4% | 1.895% |  |
| 11/14/2025 | Suvretta Capital Management LLC | 2,132,133 | $80.85M | 2.1% | +22.2% | 2.694% |  |
| 11/14/2025 | Wellington Management Group LLP | 783,445 | $29.71M | 0.0% | +578.6% | 0.990% |  |
| 11/14/2025 | FORA Capital LLC | 6,325 | $0.24M | 0.0% | N/A | 0.008% |  |
| 11/13/2025 | Invesco Ltd. | 187,986 | $7.13M | 0.0% | +630.2% | 0.238% |  |
| 11/13/2025 | Sei Investments Co. | 9,865 | $0.37M | 0.0% | N/A | 0.012% |  |
| 11/13/2025 | UBS Group AG | 89,504 | $3.39M | 0.0% | -22.3% | 0.113% |  |
| 11/13/2025 | Atika Capital Management LLC | 174,000 | $6.60M | 0.5% | N/A | 0.220% |  |
| 11/13/2025 | BNP Paribas Financial Markets | 626,148 | $23.74M | 0.0% | +15,142.2% | 0.791% |  |
| 11/13/2025 | Franklin Resources Inc. | 1,809,768 | $68.63M | 0.0% | +0.3% | 2.287% |  |
| 11/13/2025 | Capital International Investors | 2,393,396 | $90.76M | 0.0% | -17.4% | 3.024% |  |
| 11/13/2025 | Legal & General Group Plc | 45,429 | $1.72M | 0.0% | +26.0% | 0.057% |  |
| 11/13/2025 | Swiss National Bank | 88,500 | $3.36M | 0.0% | +43.0% | 0.112% |  |
| 11/13/2025 | Russell Investments Group Ltd. | 3,264 | $0.12M | 0.0% | +14,091.3% | 0.004% |  |
| 11/13/2025 | Rhenman & Partners Asset Management AB | 165,000 | $6.26M | 0.7% | N/A | 0.208% |  |
| 11/13/2025 | Blue Owl Capital Holdings LP | 100,944 | $3.83M | 1.2% | -70.0% | 0.128% |  |
| 11/12/2025 | SR One Capital Management LP | 2,113,933 | $80.16M | 11.6% | -32.4% | 3.189% |  |
| 11/12/2025 | Barclays PLC | 653,830 | $24.79M | 0.0% | +354.4% | 0.986% |  |
| 11/12/2025 | Dimensional Fund Advisors LP | 146,778 | $5.57M | 0.0% | -21.7% | 0.221% |  |
| 11/12/2025 | Victory Capital Management Inc. | 5,707 | $0.22M | 0.0% | N/A | 0.009% |  |
| 11/12/2025 | Rafferty Asset Management LLC | 31,685 | $1.20M | 0.0% | -44.8% | 0.048% |  |
| 11/12/2025 | American Century Companies Inc. | 879,682 | $33.36M | 0.0% | +5.4% | 1.327% |  |
| 11/10/2025 | Greenland Capital Management LP | 105,853 | $4.01M | 0.4% | +958.5% | 0.160% |  |
| 11/10/2025 | Ameritas Investment Partners Inc. | 3,269 | $0.12M | 0.0% | -18.2% | 0.005% |  |
| 11/10/2025 | Citigroup Inc. | 163,168 | $6.19M | 0.0% | +501.7% | 0.246% |  |
| 11/10/2025 | China Universal Asset Management Co. Ltd. | 11,621 | $0.44M | 0.0% | -11.2% | 0.018% |  |
| 11/7/2025 | Vanguard Group Inc. | 3,018,999 | $114.48M | 0.0% | +29.8% | 4.554% |  |
| 11/6/2025 | Rhumbline Advisers | 55,291 | $2.10M | 0.0% | +3.2% | 0.083% |  |
| 11/6/2025 | Profund Advisors LLC | 7,256 | $0.28M | 0.0% | -40.2% | 0.011% |  |
| 11/6/2025 | ProShare Advisors LLC | 9,055 | $0.34M | 0.0% | -13.4% | 0.014% |  |
| 11/6/2025 | Candriam S.C.A. | 567,781 | $21.53M | 0.1% | -31.1% | 0.857% |  |
| 11/5/2025 | Smartleaf Asset Management LLC | 1,017 | $40K | 0.0% | +198.2% | 0.002% |  |
| 11/5/2025 | SBI Securities Co. Ltd. | 1,126 | $43K | 0.0% | -34.7% | 0.002% |  |
| 11/5/2025 | Optimize Financial Inc | 12,207 | $0.46M | 0.2% | N/A | 0.018% |  |
| 11/4/2025 | Allianz Asset Management GmbH | 33,700 | $1.28M | 0.0% | +174.0% | 0.051% |  |
| 11/3/2025 | AlphaQuest LLC | 12,605 | $0.48M | 0.0% | -15.1% | 0.019% |  |
| 11/3/2025 | Arizona State Retirement System | 10,607 | $0.40M | 0.0% | N/A | 0.016% |  |
| 11/3/2025 | New York State Common Retirement Fund | 12,564 | $0.48M | 0.0% | +61.8% | 0.019% |  |
| 10/31/2025 | Y Intercept Hong Kong Ltd | 36,373 | $1.38M | 0.0% | +70.9% | 0.055% |  |
| 10/23/2025 | Kingswood Wealth Advisors LLC | 16,143 | $0.61M | 0.0% | N/A | 0.024% |  |
| 10/23/2025 | SG Americas Securities LLC | 100,037 | $3.79M | 0.0% | -19.3% | 0.151% |  |
| 10/22/2025 | Hennion & Walsh Asset Management Inc. | 52,848 | $2M | 0.1% | +70.0% | 0.080% |  |
| 10/20/2025 | Simplify Asset Management Inc. | 218,726 | $8.29M | 0.2% | N/A | 0.330% |  |
| 10/15/2025 | CWM LLC | 5,597 | $0.21M | 0.0% | -10.5% | 0.008% |  |
| 10/15/2025 | Swedbank AB | 299,300 | $11.35M | 0.0% | -22.0% | 0.452% |  |
| 10/9/2025 | Voya Investment Management LLC | 138,526 | $5.25M | 0.0% | +174.4% | 0.209% |  |
| 8/28/2025 | China Universal Asset Management Co. Ltd. | 13,090 | $0.18M | 0.0% | +31.0% | 0.020% |  |
| 8/15/2025 | Rafferty Asset Management LLC | 57,375 | $0.78M | 0.0% | N/A | 0.087% |  |
| 8/15/2025 | Man Group plc | 21,852 | $0.30M | 0.0% | +50.1% | 0.033% |  |
| 8/15/2025 | BNP Paribas Financial Markets | 4,108 | $56K | 0.0% | -93.3% | 0.006% |  |
| 8/15/2025 | Boothbay Fund Management LLC | 816,926 | $11.05M | 0.2% | -12.5% | 1.232% |  |
| 8/15/2025 | Bellevue Group AG | 15,556 | $0.21M | 0.0% | -5.7% | 0.023% |  |
| 8/15/2025 | Balyasny Asset Management L.P. | 205,723 | $2.78M | 0.0% | +37.8% | 0.310% |  |
| 8/15/2025 | Bank of America Corp DE | 263,356 | $3.56M | 0.0% | +78.9% | 0.397% |  |
| 8/15/2025 | Ameriprise Financial Inc. | 50,857 | $0.69M | 0.0% | N/A | 0.077% |  |
| 8/14/2025 | Nantahala Capital Management LLC | 353,982 | $4.79M | 0.2% | -55.1% | 0.543% |  |
| 8/14/2025 | Orbimed Advisors LLC | 760,351 | $10.29M | 0.3% | N/A | 1.167% |  |
| 8/14/2025 | California State Teachers Retirement System | 36,592 | $0.50M | 0.0% | +1,668.6% | 0.056% |  |
| 8/14/2025 | MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 24,237 | $0.33M | 0.0% | +41.9% | 0.037% |  |
| 8/14/2025 | Armistice Capital LLC | 178,000 | $2.41M | 0.0% | N/A | 0.273% |  |
| 8/14/2025 | The Manufacturers Life Insurance Company | 14,775 | $0.20M | 0.0% | +29.8% | 0.023% |  |
| 8/14/2025 | OCONNOR A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS LLC | 79,723 | $1.08M | 0.1% | +8.7% | 0.122% |  |
| 8/14/2025 | HighVista Strategies LLC | 150,138 | $2.03M | 0.7% | N/A | 0.230% |  |