| 11/17/2025 | Vestal Point Capital LP | 800,000 | $5.93M | 0.3% | N/A | 1.229% |  |
| 11/17/2025 | Scientech Research LLC | 16,254 | $0.12M | 0.0% | N/A | 0.025% |  |
| 11/17/2025 | Qube Research & Technologies Ltd | 147,726 | $1.10M | 0.0% | -27.4% | 0.227% |  |
| 11/17/2025 | Prelude Capital Management LLC | 10,202 | $76K | 0.0% | N/A | 0.016% |  |
| 11/17/2025 | Millennium Management LLC | 444,939 | $3.30M | 0.0% | +588.4% | 0.683% |  |
| 11/17/2025 | MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 21,265 | $0.16M | 0.0% | -16.7% | 0.033% |  |
| 11/17/2025 | Focus Partners Wealth | 11,724 | $87K | 0.0% | -8.3% | 0.018% |  |
| 11/17/2025 | Brevan Howard Capital Management LP | 46,912 | $0.35M | 0.0% | +31.2% | 0.072% |  |
| 11/17/2025 | Bank of America Corp DE | 269,643 | $2M | 0.0% | -0.6% | 0.414% |  |
| 11/14/2025 | Virtu Financial LLC | 11,952 | $89K | 0.0% | N/A | 0.018% |  |
| 11/14/2025 | Man Group plc | 40,575 | $0.30M | 0.0% | +11.5% | 0.062% |  |
| 11/14/2025 | ADAR1 Capital Management LLC | 215,752 | $1.60M | 0.2% | N/A | 0.331% |  |
| 11/14/2025 | Two Sigma Investments LP | 161,481 | $1.20M | 0.0% | -32.7% | 0.248% |  |
| 11/14/2025 | Bridgeway Capital Management LLC | 358,850 | $2.66M | 0.1% | +32.2% | 0.551% |  |
| 11/14/2025 | Squarepoint Ops LLC | 94,707 | $0.70M | 0.0% | -46.8% | 0.145% |  |
| 11/13/2025 | Marshall Wace LLP | 902,834 | $6.69M | 0.0% | +102.4% | 1.386% |  |
| 11/13/2025 | BNP Paribas Financial Markets | 9,733 | $72K | 0.0% | +88.3% | 0.015% |  |
| 11/13/2025 | Franklin Resources Inc. | 43,420 | $0.32M | 0.0% | -48.6% | 0.067% |  |
| 11/13/2025 | Russell Investments Group Ltd. | 4,318 | $32K | 0.0% | N/A | 0.007% |  |
| 11/12/2025 | Dimensional Fund Advisors LP | 632,182 | $4.68M | 0.0% | +41.1% | 0.971% |  |
| 11/12/2025 | Royce & Associates LP | 11,024 | $82K | 0.0% | +8.3% | 0.017% |  |
| 11/12/2025 | Intech Investment Management LLC | 13,405 | $99K | 0.0% | -55.1% | 0.021% |  |
| 11/10/2025 | China Universal Asset Management Co. Ltd. | 30,825 | $0.23M | 0.0% | -4.7% | 0.047% |  |
| 11/7/2025 | GSA Capital Partners LLP | 133,455 | $0.99M | 0.1% | -53.0% | 0.216% |  |
| 11/7/2025 | Vanguard Group Inc. | 2,988,953 | $22.15M | 0.0% | -4.8% | 4.840% |  |
| 11/7/2025 | JPMorgan Chase & Co. | 22,939 | $0.17M | 0.0% | -7.8% | 0.037% |  |
| 11/6/2025 | ProShare Advisors LLC | 10,175 | $75K | 0.0% | -14.2% | 0.016% |  |
| 10/29/2025 | Wealth Enhancement Advisory Services LLC | 18,543 | $0.14M | 0.0% | -7.3% | 0.030% |  |
| 10/28/2025 | Campbell & CO Investment Adviser LLC | 51,133 | $0.38M | 0.0% | N/A | 0.083% |  |
| 10/28/2025 | Wealth Effects LLC | 10,099 | $75K | 0.0% | N/A | 0.016% |  |
| 10/20/2025 | Allspring Global Investments Holdings LLC | 24,597 | $0.18M | 0.0% | N/A | 0.040% |  |
| 10/15/2025 | CWM LLC | 25,908 | $0.19M | 0.0% | -8.5% | 0.042% |  |
| 8/28/2025 | China Universal Asset Management Co. Ltd. | 32,354 | $0.15M | 0.0% | +162.5% | 0.052% |  |
| 8/27/2025 | Squarepoint Ops LLC | 178,136 | $0.80M | 0.0% | N/A | 0.288% |  |
| 8/15/2025 | Man Group plc | 36,391 | $0.16M | 0.0% | N/A | 0.059% |  |
| 8/15/2025 | Lazard Asset Management LLC | 10,857 | $48K | 0.0% | +42.9% | 0.018% |  |
| 8/15/2025 | Bridgeway Capital Management LLC | 271,400 | $1.22M | 0.0% | N/A | 0.439% |  |
| 8/15/2025 | Bank of America Corp DE | 271,164 | $1.22M | 0.0% | +941.1% | 0.439% |  |
| 8/15/2025 | AQR Capital Management LLC | 1,283,942 | $5.79M | 0.0% | +459.4% | 2.079% |  |
| 8/14/2025 | The Manufacturers Life Insurance Company | 119,836 | $0.54M | 0.0% | +2.2% | 0.194% |  |
| 8/14/2025 | Squarepoint Ops LLC | 178,136 | $0.80M | 0.0% | N/A | 0.288% |  |
| 8/14/2025 | Sei Investments Co. | 16,406 | $74K | 0.0% | N/A | 0.027% |  |
| 8/14/2025 | Qube Research & Technologies Ltd | 203,420 | $0.92M | 0.0% | +317.7% | 0.329% |  |
| 8/13/2025 | Marshall Wace LLP | 446,080 | $2.01M | 0.0% | +20.0% | 0.722% |  |
| 8/13/2025 | Stonepine Capital Management LLC | 30,000 | $0.14M | 0.1% | N/A | 0.049% |  |
| 8/13/2025 | Invesco Ltd. | 65,389 | $0.30M | 0.0% | +85.0% | 0.106% |  |
| 8/12/2025 | XTX Topco Ltd | 54,440 | $0.25M | 0.0% | N/A | 0.088% |  |
| 8/12/2025 | Prudential Financial Inc. | 12,054 | $54K | 0.0% | N/A | 0.020% |  |
| 8/12/2025 | American Century Companies Inc. | 403,045 | $1.82M | 0.0% | +301.4% | 0.653% |  |
| 8/12/2025 | Franklin Resources Inc. | 84,488 | $0.38M | 0.0% | +213.5% | 0.137% |  |
| 8/12/2025 | Hillsdale Investment Management Inc. | 60,100 | $0.27M | 0.0% | N/A | 0.097% |  |
| 8/11/2025 | Integrated Quantitative Investments LLC | 35,400 | $0.16M | 0.0% | N/A | 0.058% |  |
| 8/8/2025 | Intech Investment Management LLC | 29,870 | $0.14M | 0.0% | +35.4% | 0.049% |  |
| 8/8/2025 | Bailard Inc. | 22,500 | $0.10M | 0.0% | N/A | 0.037% |  |
| 8/8/2025 | Geode Capital Management LLC | 1,124,160 | $5.07M | 0.0% | +12.0% | 1.828% |  |
| 8/7/2025 | Los Angeles Capital Management LLC | 19,787 | $89K | 0.0% | N/A | 0.032% |  |
| 7/31/2025 | Brighton Jones LLC | 10,559 | $48K | 0.0% | N/A | 0.017% |  |
| 7/25/2025 | CWM LLC | 28,326 | $0.13M | 0.0% | +664.3% | 0.046% |  |
| 7/10/2025 | Wealth Enhancement Advisory Services LLC | 20,007 | $97K | 0.0% | N/A | 0.033% |  |
| 7/9/2025 | Pallas Capital Advisors LLC | 13,182 | $59K | 0.0% | N/A | 0.021% |  |
| 5/21/2025 | Acadian Asset Management LLC | 16,385 | $76K | 0.0% | N/A | 0.027% |  |
| 5/16/2025 | Goldman Sachs Group Inc. | 356,112 | $1.65M | 0.0% | +122.7% | 0.579% |  |
| 5/16/2025 | Parkwood LLC | 708,000 | $3.29M | 0.3% | +119.2% | 1.151% |  |
| 5/16/2025 | BVF Inc. IL | 5,660,132 | $26.26M | 1.1% | +104.7% | 9.202% |  |
| 5/16/2025 | AQR Capital Management LLC | 229,536 | $1.07M | 0.0% | N/A | 0.373% |  |
| 5/15/2025 | Trexquant Investment LP | 26,188 | $0.12M | 0.0% | N/A | 0.043% |  |
| 5/14/2025 | AlphaQuest LLC | 27,251 | $0.13M | 0.0% | -71.2% | 0.044% |  |
| 5/14/2025 | Wellington Management Group LLP | 187,731 | $0.87M | 0.0% | -15.3% | 0.305% |  |
| 5/13/2025 | American Century Companies Inc. | 100,406 | $0.47M | 0.0% | +30.7% | 0.163% |  |
| 5/13/2025 | Fox Run Management L.L.C. | 27,394 | $0.13M | 0.0% | N/A | 0.045% |  |
| 5/12/2025 | Nuveen LLC | 117,672 | $0.55M | 0.0% | N/A | 0.191% |  |
| 5/12/2025 | Invesco Ltd. | 35,346 | $0.16M | 0.0% | +175.1% | 0.057% |  |
| 5/9/2025 | Deutsche Bank AG | 24,850 | $0.12M | 0.0% | -14.5% | 0.040% |  |
| 5/9/2025 | Charles Schwab Investment Management Inc. | 361,535 | $1.68M | 0.0% | -2.4% | 0.588% |  |
| 5/7/2025 | Corton Capital Inc. | 29,348 | $0.14M | 0.4% | -9.3% | 0.048% |  |
| 5/7/2025 | TD Asset Management Inc | 172,078 | $0.80M | 0.0% | -21.8% | 0.280% |  |
| 5/6/2025 | Readystate Asset Management LP | 287,000 | $1.33M | 0.0% | N/A | 0.467% |  |
| 4/29/2025 | Bank of New York Mellon Corp | 164,145 | $0.76M | 0.0% | -3.6% | 0.267% |  |
| 4/17/2025 | Exchange Traded Concepts LLC | 18,928 | $88K | 0.0% | -36.5% | 0.031% |  |
| 3/24/2025 | Wellington Management Group LLP | 221,741 | $1.54M | 0.0% | +2.2% | 0.361% |  |
| 2/17/2025 | Vestal Point Capital LP | 425,000 | $2.95M | 0.2% | -54.3% | 0.692% |  |
| 2/17/2025 | Squarepoint Ops LLC | 31,654 | $0.22M | 0.0% | N/A | 0.052% |  |
| 2/17/2025 | Two Sigma Advisers LP | 26,000 | $0.18M | 0.0% | N/A | 0.042% |  |
| 2/17/2025 | Two Sigma Investments LP | 278,785 | $1.94M | 0.0% | +1,965.1% | 0.454% |  |
| 2/17/2025 | Suvretta Capital Management LLC | 1,563,798 | $10.85M | 0.4% | -41.2% | 2.545% |  |
| 2/17/2025 | Sherbrooke Park Advisers LLC | 14,476 | $100K | 0.0% | -27.6% | 0.024% |  |
| 2/17/2025 | Rafferty Asset Management LLC | 27,698 | $0.19M | 0.0% | N/A | 0.045% |  |
| 2/17/2025 | ProShare Advisors LLC | 14,541 | $0.10M | 0.0% | N/A | 0.024% |  |
| 2/17/2025 | Parkwood LLC | 323,000 | $2.24M | 0.2% | -24.3% | 0.526% |  |
| 2/17/2025 | Millennium Management LLC | 46,370 | $0.32M | 0.0% | +51.4% | 0.075% |  |
| 2/17/2025 | MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 24,701 | $0.17M | 0.0% | +9.2% | 0.040% |  |
| 2/17/2025 | Focus Partners Wealth | 11,122 | $77K | 0.0% | N/A | 0.018% |  |
| 2/17/2025 | Deutsche Bank AG | 29,064 | $0.20M | 0.0% | +29.6% | 0.047% |  |
| 2/17/2025 | D. E. Shaw & Co. Inc. | 70,114 | $0.49M | 0.0% | +283.3% | 0.114% |  |
| 2/17/2025 | Corton Capital Inc. | 32,366 | $0.23M | 0.1% | N/A | 0.053% |  |
| 2/17/2025 | Cubist Systematic Strategies LLC | 92,818 | $0.64M | 0.0% | N/A | 0.151% |  |
| 2/17/2025 | BVF Inc. IL | 2,764,471 | $19.19M | 0.7% | N/A | 4.499% |  |
| 2/17/2025 | Bank of America Corp DE | 63,283 | $0.44M | 0.0% | -13.8% | 0.103% |  |
| 2/17/2025 | BNP Paribas Financial Markets | 6,231 | $43K | 0.0% | N/A | 0.010% |  |
| 2/14/2025 | Jane Street Group LLC | 14,581 | $0.10M | 0.0% | -12.9% | 0.024% |  |