| 11/21/2025 | CIBC Bancorp USA Inc. | 31,140 | $0.89M | 0.0% | N/A | 0.027% |  |
| 11/17/2025 | Woodline Partners LP | 1,157,867 | $32.93M | 0.2% | -39.0% | 1.021% |  |
| 11/17/2025 | Polar Capital Holdings Plc | 2,911,634 | $82.81M | 0.4% | +15.6% | 2.568% |  |
| 11/17/2025 | MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 25,936 | $0.74M | 0.0% | -17.4% | 0.023% |  |
| 11/17/2025 | HighVista Strategies LLC | 31,831 | $0.91M | 0.2% | +65.1% | 0.028% |  |
| 11/17/2025 | Fcpm Iii Services B.V. | 9,212,384 | $262M | 52.6% | -13.4% | 8.124% |  |
| 11/17/2025 | Fred Alger Management LLC | 41,264 | $1.17M | 0.0% | +87.2% | 0.036% |  |
| 11/17/2025 | Decheng Capital LLC | 657,051 | $18.69M | 3.3% | -14.7% | 0.579% |  |
| 11/17/2025 | Bank of America Corp DE | 472,100 | $13.43M | 0.0% | -2.5% | 0.416% |  |
| 11/17/2025 | Boothbay Fund Management LLC | 40,714 | $1.16M | 0.0% | -32.2% | 0.036% |  |
| 11/17/2025 | ArrowMark Colorado Holdings LLC | 310,999 | $8.85M | 0.2% | -13.3% | 0.274% |  |
| 11/17/2025 | Alliancebernstein L.P. | 2,141,778 | $60.91M | 0.0% | -8.1% | 1.889% |  |
| 11/17/2025 | Ameriprise Financial Inc. | 145,327 | $4.13M | 0.0% | -30.2% | 0.128% |  |
| 11/14/2025 | Viking Global Investors LP | 6,475,534 | $184.16M | 0.5% | -7.2% | 5.711% |  |
| 11/14/2025 | Bellevue Group AG | 14,611 | $0.42M | 0.0% | -28.9% | 0.013% |  |
| 11/14/2025 | Deerfield Management Company L.P. | 4,266,693 | $121.35M | 1.9% | -16.6% | 3.788% |  |
| 11/14/2025 | Duquesne Family Office LLC | 1,923,700 | $54.71M | 1.3% | +131.2% | 1.708% |  |
| 11/14/2025 | ADAR1 Capital Management LLC | 114,359 | $3.25M | 0.3% | +1.8% | 0.102% |  |
| 11/14/2025 | Squarepoint Ops LLC | 20,959 | $0.60M | 0.0% | +46.8% | 0.019% |  |
| 11/14/2025 | Wellington Management Group LLP | 4,020,126 | $114.33M | 0.0% | +21.0% | 3.569% |  |
| 11/13/2025 | Kennedy Capital Management LLC | 146,715 | $4.17M | 0.1% | +972.9% | 0.130% |  |
| 11/13/2025 | UBS Group AG | 768,520 | $21.86M | 0.0% | +22.4% | 0.682% |  |
| 11/13/2025 | BNP Paribas Financial Markets | 27,328 | $0.78M | 0.0% | -6.7% | 0.024% |  |
| 11/13/2025 | Franklin Resources Inc. | 405,825 | $11.54M | 0.0% | +21.4% | 0.360% |  |
| 11/13/2025 | Capital World Investors | 9,822,711 | $279.36M | 0.0% | +17.1% | 8.721% |  |
| 11/13/2025 | Legal & General Group Plc | 45,738 | $1.30M | 0.0% | +3.4% | 0.041% |  |
| 11/13/2025 | Swiss National Bank | 87,100 | $2.48M | 0.0% | +3.8% | 0.077% |  |
| 11/13/2025 | Jefferies Financial Group Inc. | 12,000 | $0.34M | 0.0% | N/A | 0.011% |  |
| 11/12/2025 | DCF Advisers LLC | 175,250 | $4.98M | 1.6% | +1.6% | 0.156% |  |
| 11/12/2025 | Legato Capital Management LLC | 23,370 | $0.67M | 0.1% | +24.4% | 0.021% |  |
| 11/12/2025 | American Century Companies Inc. | 624,285 | $17.76M | 0.0% | +17.1% | 0.554% |  |
| 11/12/2025 | Handelsbanken Fonder AB | 405,800 | $11.54M | 0.0% | +18.8% | 0.360% |  |
| 11/12/2025 | Mesirow Financial Investment Management Inc. | 8,215 | $0.23M | 0.0% | N/A | 0.007% |  |
| 11/10/2025 | TD Asset Management Inc | 18,000 | $0.51M | 0.0% | N/A | 0.016% |  |
| 11/10/2025 | China Universal Asset Management Co. Ltd. | 19,742 | $0.56M | 0.0% | -12.4% | 0.018% |  |
| 11/7/2025 | CenterBook Partners LP | 70,613 | $2.01M | 0.1% | +3.6% | 0.063% |  |
| 11/7/2025 | Readystate Asset Management LP | 34,353 | $0.98M | 0.0% | -85.1% | 0.031% |  |
| 11/7/2025 | Vanguard Group Inc. | 172,466 | $4.91M | 0.0% | -3.6% | 0.153% |  |
| 11/7/2025 | JPMorgan Chase & Co. | 1,302,498 | $37.04M | 0.0% | -10.7% | 1.156% |  |
| 11/7/2025 | PNC Financial Services Group Inc. | 3,616 | $0.10M | 0.0% | -21.3% | 0.003% |  |
| 11/7/2025 | TimesSquare Capital Management LLC | 837,368 | $23.82M | 0.3% | -4.0% | 0.743% |  |
| 11/7/2025 | Aberdeen Group plc | 661,946 | $18.83M | 0.0% | -9.9% | 0.588% |  |
| 11/4/2025 | Marshall Financial Group Inc. ADV | 7,500 | $0.21M | 0.1% | N/A | 0.007% |  |
| 11/4/2025 | Atle Fund Management AB | 193,625 | $5.51M | 2.2% | +23.2% | 0.172% |  |
| 11/4/2025 | Keybank National Association OH | 16,014 | $0.46M | 0.0% | N/A | 0.014% |  |
| 11/4/2025 | Lisanti Capital Growth LLC | 47,445 | $1.35M | 0.3% | -3.4% | 0.042% |  |
| 11/3/2025 | Arizona State Retirement System | 13,251 | $0.38M | 0.0% | +3.8% | 0.012% |  |
| 11/3/2025 | Knights of Columbus Asset Advisors LLC | 33,610 | $0.96M | 0.1% | +2.4% | 0.030% |  |
| 11/3/2025 | New York State Common Retirement Fund | 26,680 | $0.76M | 0.0% | N/A | 0.024% |  |
| 10/30/2025 | Jennison Associates LLC | 4,198,554 | $119.41M | 0.1% | +42.5% | 3.728% |  |
| 10/28/2025 | Wolverine Asset Management LLC | 2,429 | $69K | 0.0% | N/A | 0.002% |  |
| 10/21/2025 | Mather Group LLC. | 1,000 | $28K | 0.0% | N/A | 0.001% |  |
| 10/9/2025 | Voya Investment Management LLC | 19,300 | $0.55M | 0.0% | N/A | 0.017% |  |
| 10/7/2025 | Thurston Springer Miller Herd & Titak Inc. | 1,067 | $30K | 0.1% | N/A | 0.001% |  |
| 8/28/2025 | China Universal Asset Management Co. Ltd. | 22,549 | $0.41M | 0.0% | +2.4% | 0.020% |  |
| 8/15/2025 | Duquesne Family Office LLC | 832,175 | $15.07M | 0.4% | +4.0% | 0.741% |  |
| 8/15/2025 | Exome Asset Management LLC | 36,574 | $0.66M | 0.4% | N/A | 0.033% |  |
| 8/15/2025 | Frazier Life Sciences Management L.P. | 16,607,074 | $300.75M | 12.0% | +3.0% | 14.792% |  |
| 8/15/2025 | BNP Paribas Financial Markets | 29,277 | $0.53M | 0.0% | +4.5% | 0.026% |  |
| 8/15/2025 | Boothbay Fund Management LLC | 60,054 | $1.09M | 0.0% | -53.4% | 0.053% |  |
| 8/15/2025 | Bellevue Group AG | 20,555 | $0.37M | 0.0% | -5.7% | 0.018% |  |
| 8/15/2025 | Bank of America Corp DE | 484,004 | $8.77M | 0.0% | -26.6% | 0.431% |  |
| 8/15/2025 | Adage Capital Partners GP L.L.C. | 3,013,009 | $54.57M | 0.1% | +54.5% | 2.684% |  |
| 8/15/2025 | Ameriprise Financial Inc. | 208,081 | $3.77M | 0.0% | +118.7% | 0.185% |  |
| 8/14/2025 | California State Teachers Retirement System | 47,862 | $0.87M | 0.0% | +146.7% | 0.043% |  |
| 8/14/2025 | Maverick Capital Ltd. | 1,531,874 | $27.74M | 0.4% | +178.8% | 1.364% |  |
| 8/14/2025 | MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 31,383 | $0.57M | 0.0% | +5.4% | 0.028% |  |
| 8/14/2025 | Alliancebernstein L.P. | 2,331,583 | $42.23M | 0.0% | +4.0% | 2.077% |  |
| 8/14/2025 | The Manufacturers Life Insurance Company | 10,868 | $0.20M | 0.0% | +5.3% | 0.010% |  |
| 8/14/2025 | HighVista Strategies LLC | 19,274 | $0.35M | 0.1% | N/A | 0.017% |  |
| 8/14/2025 | Stempoint Capital LP | 152,652 | $2.77M | 0.9% | +46.0% | 0.136% |  |
| 8/14/2025 | AXA S.A. | 242,916 | $4.40M | 0.0% | +0.2% | 0.216% |  |
| 8/13/2025 | Affinity Asset Advisors LLC | 275,000 | $4.98M | 0.7% | -21.4% | 0.245% |  |
| 8/13/2025 | First Trust Advisors LP | 131,430 | $2.38M | 0.0% | +10.4% | 0.117% |  |
| 8/13/2025 | Kennedy Capital Management LLC | 13,675 | $0.25M | 0.0% | N/A | 0.012% |  |
| 8/13/2025 | Saturn V Capital Management LP | 220,695 | $4M | 1.6% | +89.7% | 0.197% |  |
| 8/13/2025 | Invesco Ltd. | 134,035 | $2.43M | 0.0% | +12.7% | 0.119% |  |
| 8/13/2025 | Virtus Investment Advisers LLC | 4,471 | $81K | 0.0% | -31.7% | 0.004% |  |
| 8/12/2025 | American Century Companies Inc. | 532,916 | $9.65M | 0.0% | +0.8% | 0.475% |  |
| 8/12/2025 | Franklin Resources Inc. | 334,212 | $6.05M | 0.0% | +30.6% | 0.298% |  |
| 8/12/2025 | Legal & General Group Plc | 44,235 | $0.80M | 0.0% | +33.5% | 0.039% |  |
| 8/12/2025 | JPMorgan Chase & Co. | 1,458,897 | $26.42M | 0.0% | +47.2% | 1.299% |  |
| 8/12/2025 | Swiss National Bank | 83,900 | $1.52M | 0.0% | +18.3% | 0.075% |  |
| 8/12/2025 | Handelsbanken Fonder AB | 341,600 | $6.19M | 0.0% | +31.4% | 0.304% |  |
| 8/8/2025 | Letko Brosseau & Associates Inc. | 11,775 | $0.21M | 0.0% | N/A | 0.010% |  |
| 8/8/2025 | Geode Capital Management LLC | 99,457 | $1.80M | 0.0% | +15.9% | 0.089% |  |
| 8/8/2025 | TimesSquare Capital Management LLC | 872,537 | $15.80M | 0.2% | -2.1% | 0.777% |  |
| 8/5/2025 | Bank of New York Mellon Corp | 352,952 | $6.39M | 0.0% | N/A | 0.314% |  |
| 8/1/2025 | Jennison Associates LLC | 2,946,103 | $53.35M | 0.0% | -25.8% | 2.624% |  |
| 8/1/2025 | Teacher Retirement System of Texas | 11,700 | $0.21M | 0.0% | N/A | 0.010% |  |
| 7/24/2025 | Aberdeen Group plc | 735,032 | $13.31M | 0.0% | +95.0% | 0.655% |  |
| 7/23/2025 | KLP Kapitalforvaltning AS | 9,100 | $0.17M | 0.0% | +51.7% | 0.008% |  |
| 7/22/2025 | Knights of Columbus Asset Advisors LLC | 32,833 | $0.60M | 0.0% | N/A | 0.029% |  |
| 7/21/2025 | Mirae Asset Global Investments Co. Ltd. | 4,337 | $79K | 0.0% | +18.0% | 0.004% |  |
| 7/14/2025 | Avanza Fonder AB | 7,505 | $0.14M | 0.0% | +21.0% | 0.007% |  |
| 7/14/2025 | Atle Fund Management AB | 157,223 | $2.85M | 1.2% | +45.9% | 0.140% |  |
| 7/8/2025 | PTM Wealth Management LLC | 12,900 | $0.26M | 0.2% | N/A | 0.011% |  |
| 5/19/2025 | UBS AM A Distinct Business Unit of UBS Asset Management Americas LLC | 288,134 | $5.90M | 0.0% | +13.6% | 0.262% |  |
| 5/16/2025 | Woodline Partners LP | 2,442,397 | $50M | 0.3% | +0.5% | 2.224% |  |
| 5/16/2025 | Fred Alger Management LLC | 27,421 | $0.56M | 0.0% | -66.0% | 0.025% |  |