| 11/17/2025 | Jacobs Levy Equity Management Inc. | 367,113 | $0.54M | 0.0% | N/A | 0.597% |  |
| 11/17/2025 | Woodline Partners LP | 4,504,817 | $6.67M | 0.0% | +91.8% | 7.331% |  |
| 11/17/2025 | XTX Topco Ltd | 466,984 | $0.69M | 0.0% | +8.9% | 0.760% |  |
| 11/17/2025 | Voleon Capital Management LP | 149,041 | $0.22M | 0.0% | N/A | 0.243% |  |
| 11/17/2025 | Qube Research & Technologies Ltd | 49,515 | $73K | 0.0% | -67.4% | 0.081% |  |
| 11/17/2025 | Millennium Management LLC | 537,337 | $0.80M | 0.0% | -36.8% | 0.874% |  |
| 11/17/2025 | Jain Global LLC | 25,037 | $37K | 0.0% | -82.3% | 0.041% |  |
| 11/17/2025 | Bank of America Corp DE | 708,056 | $1.05M | 0.0% | +47.3% | 1.152% |  |
| 11/17/2025 | Algert Global LLC | 104,382 | $0.15M | 0.0% | +17.7% | 0.170% |  |
| 11/14/2025 | Two Sigma Investments LP | 783,255 | $1.16M | 0.0% | +181.6% | 1.275% |  |
| 11/14/2025 | Squarepoint Ops LLC | 33,842 | $50K | 0.0% | -78.6% | 0.055% |  |
| 11/14/2025 | Prosight Management LP | 20,487 | $30K | 0.0% | -97.6% | 0.033% |  |
| 11/13/2025 | UBS Group AG | 1,322,017 | $1.96M | 0.0% | -50.0% | 2.151% |  |
| 11/13/2025 | BNP Paribas Financial Markets | 182,356 | $0.27M | 0.0% | +17.9% | 0.297% |  |
| 11/12/2025 | Dimensional Fund Advisors LP | 151,673 | $0.23M | 0.0% | -52.0% | 0.247% |  |
| 11/10/2025 | Peapod Lane Capital LLC | 1,097,028 | $1.62M | 1.5% | +22.7% | 1.787% |  |
| 11/10/2025 | Monaco Asset Management SAM | 822,693 | $1.22M | 0.1% | +17.1% | 1.340% |  |
| 11/7/2025 | GSA Capital Partners LLP | 160,884 | $0.24M | 0.0% | +1,037.6% | 0.262% |  |
| 11/7/2025 | Vanguard Group Inc. | 2,775,938 | $4.11M | 0.0% | -7.5% | 4.522% |  |
| 11/7/2025 | JPMorgan Chase & Co. | 2,130,489 | $3.15M | 0.0% | +8.8% | 3.471% |  |
| 11/3/2025 | Federated Hermes Inc. | 55,296 | $82K | 0.0% | -35.3% | 0.090% |  |
| 10/23/2025 | SG Americas Securities LLC | 16,783 | $25K | 0.0% | -42.8% | 0.027% |  |
| 10/20/2025 | HighMark Wealth Management LLC | 219,000 | $0.32M | 0.1% | +55.3% | 0.357% |  |
| 10/16/2025 | Rice Hall James & Associates LLC | 144,843 | $0.21M | 0.0% | -10.2% | 0.236% |  |
| 8/15/2025 | Rangeley Capital LLC | 60,220 | $70K | 0.1% | +20.4% | 0.098% |  |
| 8/15/2025 | Oxford Asset Management LLP | 33,045 | $38K | 0.0% | -28.1% | 0.054% |  |
| 8/15/2025 | Engineers Gate Manager LP | 31,423 | $36K | 0.0% | +139.4% | 0.051% |  |
| 8/15/2025 | BNP Paribas Financial Markets | 154,691 | $0.18M | 0.0% | -16.1% | 0.252% |  |
| 8/15/2025 | Bridgeway Capital Management LLC | 82,300 | $95K | 0.0% | N/A | 0.134% |  |
| 8/15/2025 | Bank of America Corp DE | 480,530 | $0.56M | 0.0% | -47.8% | 0.783% |  |
| 8/14/2025 | Jane Street Group LLC | 323,412 | $0.38M | 0.0% | +136.6% | 0.527% |  |
| 8/14/2025 | Canada Pension Plan Investment Board | 30,800 | $36K | 0.0% | N/A | 0.050% |  |
| 8/14/2025 | Redmile Group LLC | 1,632,577 | $1.89M | 0.2% | -20.5% | 2.659% |  |
| 8/14/2025 | Sei Investments Co. | 297,291 | $0.35M | 0.0% | N/A | 0.484% |  |
| 8/14/2025 | Qube Research & Technologies Ltd | 151,662 | $0.18M | 0.0% | N/A | 0.247% |  |
| 8/14/2025 | Federated Hermes Inc. | 85,421 | $99K | 0.0% | +44.3% | 0.139% |  |
| 8/13/2025 | Jump Financial LLC | 25,473 | $30K | 0.0% | N/A | 0.041% |  |
| 8/13/2025 | CW Advisors LLC | 199,920 | $0.23M | 0.0% | -52.7% | 0.326% |  |
| 8/13/2025 | Quadrature Capital Ltd | 61,221 | $71K | 0.0% | -9.3% | 0.100% |  |
| 8/12/2025 | XTX Topco Ltd | 429,010 | $0.50M | 0.0% | -8.1% | 0.699% |  |
| 8/12/2025 | JPMorgan Chase & Co. | 1,958,433 | $2.27M | 0.0% | +307.1% | 3.190% |  |
| 8/12/2025 | Catalyst Funds Management Pty Ltd | 34,015 | $39K | 0.0% | N/A | 0.055% |  |
| 8/8/2025 | Geode Capital Management LLC | 582,586 | $0.68M | 0.0% | -56.9% | 0.949% |  |
| 8/7/2025 | Monaco Asset Management SAM | 702,393 | $0.82M | 0.1% | N/A | 1.144% |  |
| 7/31/2025 | Peapod Lane Capital LLC | 893,730 | $1.04M | 1.0% | +39.2% | 1.456% |  |
| 7/25/2025 | Vanguard Personalized Indexing Management LLC | 35,540 | $41K | 0.0% | +119.1% | 0.058% |  |
| 7/21/2025 | HighMark Wealth Management LLC | 141,000 | $0.16M | 0.1% | -10.5% | 0.230% |  |
| 6/27/2025 | Goldman Sachs Group Inc. | 475,877 | $0.64M | 0.0% | +6.5% | 0.775% |  |
| 5/21/2025 | Acadian Asset Management LLC | 1,220,446 | $1.64M | 0.0% | N/A | 1.988% |  |
| 5/19/2025 | Jane Street Group LLC | 136,716 | $0.19M | 0.0% | -1,270.0% | 0.223% |  |
| 5/16/2025 | Woodline Partners LP | 2,514,084 | $3.39M | 0.0% | +1,875.0% | 4.096% |  |
| 5/16/2025 | Voleon Capital Management LP | 72,027 | $97K | 0.0% | N/A | 0.117% |  |
| 5/16/2025 | Goldman Sachs Group Inc. | 475,877 | $0.64M | 0.0% | +6.5% | 0.775% |  |
| 5/16/2025 | Cormorant Asset Management LP | 3,000,000 | $4.05M | 0.3% | N/A | 4.887% |  |
| 5/16/2025 | AQR Capital Management LLC | 72,057 | $97K | 0.0% | N/A | 0.117% |  |
| 5/16/2025 | Allostery Investments LP | 441,686 | $0.60M | 0.9% | N/A | 0.720% |  |
| 5/15/2025 | Redmile Group LLC | 2,053,559 | $2.77M | 0.3% | -29.1% | 3.345% |  |
| 5/15/2025 | Royal Bank of Canada | 362,702 | $0.49M | 0.0% | +222.4% | 0.591% |  |
| 5/14/2025 | CW Advisors LLC | 422,311 | $0.57M | 0.0% | N/A | 0.688% |  |
| 5/13/2025 | Algert Global LLC | 88,690 | $0.12M | 0.0% | -17.6% | 0.144% |  |
| 5/13/2025 | American Century Companies Inc. | 110,093 | $0.15M | 0.0% | +9.2% | 0.179% |  |
| 5/12/2025 | Nuveen LLC | 233,585 | $0.32M | 0.0% | N/A | 0.381% |  |
| 5/12/2025 | Invesco Ltd. | 68,963 | $93K | 0.0% | +42.2% | 0.112% |  |
| 5/9/2025 | Deutsche Bank AG | 47,472 | $64K | 0.0% | -98.1% | 0.077% |  |
| 5/9/2025 | Charles Schwab Investment Management Inc. | 389,349 | $0.53M | 0.0% | -15.2% | 0.634% |  |
| 5/8/2025 | XTX Topco Ltd | 466,842 | $0.63M | 0.0% | N/A | 0.761% |  |
| 5/8/2025 | Federated Hermes Inc. | 59,209 | $80K | 0.0% | +1,557.6% | 0.096% |  |
| 5/1/2025 | Rice Hall James & Associates LLC | 152,994 | $0.21M | 0.0% | -4.7% | 0.249% |  |
| 4/30/2025 | Peapod Lane Capital LLC | 642,193 | $0.87M | 1.0% | N/A | 1.046% |  |
| 4/29/2025 | Bank of New York Mellon Corp | 173,025 | $0.23M | 0.0% | -6.2% | 0.282% |  |
| 4/24/2025 | HighMark Wealth Management LLC | 157,500 | $0.21M | 0.1% | +110.0% | 0.257% |  |
| 2/25/2025 | Polar Asset Management Partners Inc. | 62,600 | $0.82M | 0.0% | -63.2% | 0.103% |  |
| 2/18/2025 | Frazier Life Sciences Management L.P. | 1,120,803 | $14.76M | 0.6% | N/A | 1.842% |  |
| 2/17/2025 | UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 139,574 | $1.84M | 0.0% | +18.3% | 0.229% |  |
| 2/17/2025 | Woodline Partners LP | 127,295 | $1.68M | 0.0% | +14.0% | 0.209% |  |
| 2/17/2025 | Two Sigma Investments LP | 97,078 | $1.28M | 0.0% | -28.2% | 0.160% |  |
| 2/17/2025 | Two Sigma Advisers LP | 135,700 | $1.79M | 0.0% | -14.0% | 0.223% |  |
| 2/17/2025 | Redmile Group LLC | 2,895,478 | $38.13M | 2.7% | -9.4% | 4.758% |  |
| 2/17/2025 | Polar Asset Management Partners Inc. | 62,600 | $0.82M | 0.0% | -63.2% | 0.103% |  |
| 2/17/2025 | ProShare Advisors LLC | 18,931 | $0.25M | 0.0% | +31.8% | 0.031% |  |
| 2/17/2025 | Paradigm Biocapital Advisors LP | 3,197,050 | $42.11M | 1.5% | +3.0% | 5.254% |  |
| 2/17/2025 | Nuveen Asset Management LLC | 206,947 | $2.73M | 0.0% | -38.3% | 0.340% |  |
| 2/17/2025 | OCONNOR A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS LLC | 103,563 | $1.36M | 0.1% | +22.0% | 0.170% |  |
| 2/17/2025 | Granahan Investment Management LLC | 527,147 | $6.94M | 0.3% | -28.6% | 0.866% |  |
| 2/17/2025 | Deutsche Bank AG | 2,551,865 | $33.61M | 0.0% | +66.3% | 4.194% |  |
| 2/17/2025 | Corton Capital Inc. | 10,497 | $0.14M | 0.1% | N/A | 0.017% |  |
| 2/17/2025 | Bank of America Corp DE | 120,977 | $1.59M | 0.0% | -80.7% | 0.199% |  |
| 2/17/2025 | BNP Paribas Financial Markets | 7,512 | $99K | 0.0% | N/A | 0.012% |  |
| 2/14/2025 | First Light Asset Management LLC | 1,681,110 | $22.14M | 2.1% | -34.7% | 2.763% |  |
| 2/14/2025 | Northern Trust Corp | 555,600 | $7.32M | 0.0% | +10.7% | 0.913% |  |
| 2/14/2025 | Aquatic Capital Management LLC | 5,596 | $74K | 0.0% | +1,299.0% | 0.009% |  |
| 2/14/2025 | Blue Owl Capital Holdings LP | 2,769,199 | $36.47M | 8.6% | -7.8% | 4.551% |  |
| 2/14/2025 | Adage Capital Partners GP L.L.C. | 649,660 | $8.56M | 0.0% | N/A | 1.068% |  |
| 2/14/2025 | Price T Rowe Associates Inc. MD | 4,634,486 | $61.04M | 0.0% | -4.1% | 7.616% |  |
| 2/14/2025 | Silverarc Capital Management LLC | 1,315,601 | $17.33M | 3.8% | N/A | 2.162% |  |
| 2/14/2025 | Rock Springs Capital Management LP | 404,796 | $5.33M | 0.2% | +5.1% | 0.665% |  |
| 2/14/2025 | MetLife Investment Management LLC | 36,788 | $0.48M | 0.0% | +11.9% | 0.060% |  |
| 2/14/2025 | Dimensional Fund Advisors LP | 547,297 | $7.21M | 0.0% | +20.0% | 0.899% |  |
| 2/13/2025 | Marshall Wace LLP | 53,880 | $0.71M | 0.0% | N/A | 0.089% |  |
| 2/13/2025 | Jump Financial LLC | 19,402 | $0.26M | 0.0% | N/A | 0.032% |  |