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PTGX Insider Trading

Insider Ownership Percentage: 4.90%
Insider Buying (Last 12 Months): $0.00
Insider Selling (Last 12 Months): $22,464,292.97

Protagonist Therapeutics Insider Trading History Chart

This chart shows the insider buying and selling history at Protagonist Therapeutics by year and by quarter.

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Protagonist Therapeutics Share Price & Price History

Current Price: $99.00
Price Change: ▼ Price Decrease of -2.68 (-2.64%)
As of 03/20/2026 03:59 PM ET

This chart shows the closing price history over time for PTGX up to the past year.

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Days: 30 | 90 | 365

Protagonist Therapeutics Insider Trading History

Transaction DateInsider NameTitleBuy/SellNumber of SharesAverage Share PriceTotal TransactionShares Held After TransactionDetails
2/17/2026Lewis T WilliamsDirectorSell18,000$82.42$1,483,560.007,825View SEC Filing Icon  
2/6/2026William D. WaddillDirectorSell20,000$83.68$1,673,600.007,825View SEC Filing Icon  
1/27/2026Arturo MolinaInsiderSell5,000$82.00$410,000.0084,115View SEC Filing Icon  
1/27/2026Asif AliCFOSell46,203$83.13$3,840,855.3960,320View SEC Filing Icon  
1/27/2026Dinsesh V. PatelCEOSell4,068$83.19$338,416.92574,505View SEC Filing Icon  
1/26/2026Dinsesh V. PatelCEOSell24,890$84.03$2,091,506.70574,505View SEC Filing Icon  
1/23/2026Arturo MolinaInsiderSell13,151$82.42$1,083,905.4284,115View SEC Filing Icon  
1/23/2026Dinsesh V. PatelCEOSell19,315$84.59$1,633,855.85574,505View SEC Filing Icon  
1/20/2026Arturo MolinaInsiderSell9,514$82.48$784,714.7297,266View SEC Filing Icon  
1/20/2026Asif AliCFOSell8,588$82.48$708,338.2478,077View SEC Filing Icon  
1/20/2026Dinsesh V. PatelCEOSell34,438$82.48$2,840,446.24580,505View SEC Filing Icon  
10/10/2025William D. WaddillDirectorSell12,000$81.62$979,440.005,130View SEC Filing Icon  
9/22/2025William D. WaddillDirectorSell4,000$64.25$257,000.005,130View SEC Filing Icon  
8/27/2025William D. WaddillDirectorSell4,000$59.25$237,000.009,130View SEC Filing Icon  
7/25/2025Dinsesh V. PatelCEOSell10,415$54.78$570,533.70520,603View SEC Filing Icon  
7/23/2025Dinsesh V. PatelCEOSell17,520$54.79$959,920.80531,018View SEC Filing Icon  
7/22/2025Dinsesh V. PatelCEOSell22,065$55.05$1,214,678.25548,538View SEC Filing Icon  
7/21/2025Dinsesh V. PatelCEOSell12,859$54.86$705,444.74570,603View SEC Filing Icon  
6/10/2025Arturo MolinaInsiderSell10,000$57.03$570,300.0083,892View SEC Filing Icon  
4/22/2025Asif AliCFOSell1,756$46.00$80,776.0061,065View SEC Filing Icon  
3/17/2025William D. WaddillDirectorSell4,000$54.25$217,000.0013,130View SEC Filing Icon  
3/13/2025Arturo MolinaInsiderSell30,514$55.74$1,700,850.3683,892View SEC Filing Icon  
3/12/2025Asif AliCFOSell24,903$58.73$1,462,553.1962,821View SEC Filing Icon  
2/19/2025Dinsesh V. PatelCEOSell5,359$38.18$204,606.62540,260View SEC Filing Icon  
11/27/2024Arturo MolinaInsiderSell26,000$44.70$1,162,200.0046,444View SEC Filing Icon  
11/25/2024Dinsesh V. PatelCEOSell78,520$46.96$3,687,299.20435,208View SEC Filing Icon  
11/25/2024Suneel GuptaInsiderSell103,437$46.04$4,762,239.48256,174View SEC Filing Icon  
11/15/2024Arturo MolinaInsiderSell1,906$40.98$78,107.8846,444View SEC Filing Icon  
9/11/2024Asif AliCFOSell14,203$44.49$631,891.4734,960View SEC Filing Icon  
9/10/2024William D. WaddillDirectorSell8,000$45.00$360,000.0012,000View SEC Filing Icon  
7/24/2024William D. WaddillDirectorSell8,000$40.00$320,000.0012,000View SEC Filing Icon  
6/7/2024Dinsesh V. PatelCEOSell35,000$35.19$1,231,650.00515,415View SEC Filing Icon  
6/7/2024William D. WaddillDirectorSell8,000$35.00$280,000.0012,000View SEC Filing Icon  
4/18/2024Asif AliCFOSell1,234$25.11$30,985.7437,163View SEC Filing Icon  
4/1/2024Dinsesh V. PatelCEOSell25,000$28.31$707,750.00549,590View SEC Filing Icon  
3/1/2024Asif AliCFOSell14,248$32.24$459,355.5238,397View SEC Filing Icon  
3/1/2024Dinsesh V. PatelCEOSell30,000$31.62$948,600.00574,590View SEC Filing Icon  
3/1/2024William D. WaddillDirectorSell12,975$31.34$406,636.5012,000View SEC Filing Icon  
1/9/2024Suneel GuptaInsiderSell5,000$25.00$125,000.00187,567View SEC Filing Icon  
See Full Table

SEC Filings (Institutional Ownership Changes) for Protagonist Therapeutics (NASDAQ:PTGX)

98.63% of Protagonist Therapeutics stock is owned by institutions. Institutional ownership can be a sign of analyst confidence in the fundamentals of the stock.

Institutional Buying and Selling by Quarter

This chart shows the instiutional buying and selling at PTGX by year and by quarter.

Skip Institutional Buying and Selling Chart and Table DataRead Chart Data in Institutional Trading History Table

Protagonist Therapeutics Institutional Trading History

Reporting DateHedge FundShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
3/17/2026Rockefeller Capital Management L.P.3,292$0.29M0.0%+10.5%0.005%Search for SEC Filing on Google Icon
2/26/2026Seven Fleet Capital Management LP8,000$0.70M0.5%N/A0.013%Search for SEC Filing on Google Icon
2/19/2026Invesco Ltd.1,567,840$136.94M0.0%+56.2%2.508%Search for SEC Filing on Google Icon
2/18/2026Vident Advisory LLC4,191$0.37M0.0%-17.3%0.007%Search for SEC Filing on Google Icon
2/18/2026State of Tennessee Department of Treasury23,526$1.92M0.0%-11.2%0.038%Search for SEC Filing on Google Icon
2/18/2026Mackenzie Financial Corp3,648$0.32M0.0%-10.2%0.006%Search for SEC Filing on Google Icon
2/18/2026KVP Capital Advisors LP53,000$4.63M4.5%N/A0.085%Search for SEC Filing on Google Icon
2/18/2026Virtus Investment Advisers LLC2,790$0.24M0.1%+38.1%0.004%Search for SEC Filing on Google Icon
2/18/2026Wellington Management Group LLP3,171,423$276.99M0.1%+66.2%5.073%Search for SEC Filing on Google Icon
2/18/2026SummitTX Capital L.P.42,266$3.69M0.1%+34.2%0.068%Search for SEC Filing on Google Icon
2/18/2026RTW Investments LP5,059,053$441.86M4.4%-12.1%8.092%Search for SEC Filing on Google Icon
2/18/2026Orbimed Advisors LLC21,700$1.90M0.0%N/A0.035%Search for SEC Filing on Google Icon
2/18/2026Perceptive Advisors LLC1,350,425$117.95M2.1%+31.1%2.160%Search for SEC Filing on Google Icon
2/18/2026Millennium Management LLC17,391$1.52M0.0%-86.4%0.028%Search for SEC Filing on Google Icon
2/18/2026Inspire Investing LLC5,460$0.48M0.0%-21.3%0.009%Search for SEC Filing on Google Icon
2/18/2026Janus Henderson Group PLC2,649,981$231.36M0.1%+140.7%4.239%Search for SEC Filing on Google Icon
2/18/2026Gotham Asset Management LLC21,595$1.89M0.0%-2.7%0.035%Search for SEC Filing on Google Icon
2/18/2026Elmind Capital LP38,000$3.32M1.0%N/A0.061%Search for SEC Filing on Google Icon
2/18/2026Eversept Partners LP52,961$4.63M0.2%N/A0.085%Search for SEC Filing on Google Icon
2/18/2026Commodore Capital LP450,000$39.30M2.6%-56.1%0.720%Search for SEC Filing on Google Icon
2/18/2026Bamco Inc. NY8,300$0.73M0.0%N/A0.013%Search for SEC Filing on Google Icon
2/17/2026Guggenheim Capital LLC31,096$2.72M0.0%+67.3%0.050%Search for SEC Filing on Google Icon
2/17/2026ADAR1 Capital Management LLC1,049,168$91.63M6.7%+6.1%1.678%Search for SEC Filing on Google Icon
2/17/2026AQR Capital Management LLC6,954$0.61M0.0%-18.9%0.011%Search for SEC Filing on Google Icon
2/17/2026EFG International AG72,623$6.34M0.1%N/A0.116%Search for SEC Filing on Google Icon
2/17/2026MPM Bioimpact LLC199,471$17.42M2.0%N/A0.319%Search for SEC Filing on Google Icon
2/17/2026Jain Global LLC12,850$1.12M0.0%-13.5%0.021%Search for SEC Filing on Google Icon
2/17/2026Pentwater Capital Management LP50,000$4.37M0.0%N/A0.080%Search for SEC Filing on Google Icon
2/17/2026Farallon Capital Management LLC6,144,006$536.62M2.5%-0.8%9.827%Search for SEC Filing on Google Icon
2/17/2026Price T Rowe Associates Inc. MD1,400,738$122.34M0.0%+14.8%2.240%Search for SEC Filing on Google Icon
2/17/2026Osaic Holdings Inc.4,201$0.37M0.0%+202.0%0.007%Search for SEC Filing on Google Icon
2/17/2026Adage Capital Partners GP L.L.C.232,836$20.34M0.0%-67.6%0.372%Search for SEC Filing on Google Icon
2/17/2026California State Teachers Retirement System48,033$4.20M0.0%+1.3%0.077%Search for SEC Filing on Google Icon
2/17/2026Diadema Partners LP22,700$1.98M0.3%-55.7%0.036%Search for SEC Filing on Google Icon
2/17/2026Russell Investments Group Ltd.5,723$0.50M0.0%-3.4%0.009%Search for SEC Filing on Google Icon
2/17/2026Maryland State Retirement & Pension System8,603$0.75M0.0%+2.3%0.014%Search for SEC Filing on Google Icon
2/17/2026State of Wisconsin Investment Board34,786$3.04M0.0%-15.0%0.056%Search for SEC Filing on Google Icon
2/17/2026Captrust Financial Advisors2,732$0.24M0.0%-17.5%0.004%Search for SEC Filing on Google Icon
2/17/2026Royal Bank of Canada3,183$0.28M0.0%-95.5%0.005%Search for SEC Filing on Google Icon
2/17/2026Persistent Asset Partners Ltd7,908$0.69M0.3%-32.9%0.013%Search for SEC Filing on Google Icon
2/16/2026Truvestments Capital LLC1,161$0.10M0.0%+60.8%0.002%Search for SEC Filing on Google Icon
2/16/2026Panagora Asset Management Inc.125,384$10.95M0.0%-15.7%0.201%Search for SEC Filing on Google Icon
2/16/2026Mariner LLC7,620$0.67M0.0%-43.8%0.012%Search for SEC Filing on Google Icon
2/16/2026NEXTBio Capital Management LP229,619$20.06M11.8%N/A0.367%Search for SEC Filing on Google Icon
2/16/2026Fieldview Capital Management LLC5,841$0.51M0.1%N/A0.009%Search for SEC Filing on Google Icon
2/16/2026Kennedy Capital Management LLC221,444$19.34M0.4%+6.2%0.354%Search for SEC Filing on Google Icon
2/16/2026Dymon Asia Capital Singapore PTE. LTD.10,000$0.87M0.1%N/A0.016%Search for SEC Filing on Google Icon
2/16/2026Barclays PLC187,642$16.39M0.0%+9.5%0.300%Search for SEC Filing on Google Icon
2/13/2026FORA Capital LLC9,130$0.79M0.1%+147.8%0.015%Search for SEC Filing on Google Icon
2/13/2026Marshall Wace LLP1,024,925$89.52M0.1%-5.6%1.639%Search for SEC Filing on Google Icon
2/13/2026The Manufacturers Life Insurance Company 113,340$9.89M0.0%-16.1%0.181%Search for SEC Filing on Google Icon
2/13/2026Quinn Opportunity Partners LLC55,259$4.83M0.2%N/A0.088%Search for SEC Filing on Google Icon
2/13/2026Soros Fund Management LLC100,000$8.73M0.1%N/A0.160%Search for SEC Filing on Google Icon
2/13/2026CANADA LIFE ASSURANCE Co49,640$4.33M0.0%+2.5%0.079%Search for SEC Filing on Google Icon
2/13/2026Segall Bryant & Hamill LLC129,060$11.27M0.2%+4.8%0.206%Search for SEC Filing on Google Icon
2/13/2026Affinity Asset Advisors LLC172,125$15.03M0.9%-22.0%0.275%Search for SEC Filing on Google Icon
2/13/2026Hudson Bay Capital Management LP109,615$9.57M0.0%N/A0.175%Search for SEC Filing on Google Icon
2/13/2026Smartleaf Asset Management LLC1,727$0.15M0.0%+23.1%0.003%Search for SEC Filing on Google Icon
2/13/2026Greenline Wealth Management LLC304$27K0.0%N/A0.000%Search for SEC Filing on Google Icon
2/13/2026Morgan Stanley879,024$76.77M0.0%+14.4%1.406%Search for SEC Filing on Google Icon
2/13/2026Schroder Investment Management Group45,254$3.95M0.0%N/A0.072%Search for SEC Filing on Google Icon
2/13/2026Public Sector Pension Investment Board203,426$17.77M0.1%-10.8%0.325%Search for SEC Filing on Google Icon
2/13/2026Rafferty Asset Management LLC63,661$5.56M0.0%-14.9%0.102%Search for SEC Filing on Google Icon
2/13/2026First Trust Advisors LP46,454$4.06M0.0%-25.9%0.074%Search for SEC Filing on Google Icon
2/13/2026Headlands Technologies LLC17,079$1.49M0.1%N/A0.027%Search for SEC Filing on Google Icon
2/13/2026Birchview Capital LP55,000$4.80M2.8%+14.6%0.088%Search for SEC Filing on Google Icon
2/13/2026Alyeska Investment Group L.P.199,523$17.43M0.0%N/A0.319%Search for SEC Filing on Google Icon
2/13/2026Charles Schwab Investment Management Inc.556,762$48.63M0.0%+0.7%0.891%Search for SEC Filing on Google Icon
2/13/2026Police & Firemen s Retirement System of New Jersey15,834$1.38M0.0%-1.8%0.025%Search for SEC Filing on Google Icon
2/13/2026State Street Corp3,199,729$279.46M0.0%+1.1%5.118%Search for SEC Filing on Google Icon
2/13/2026UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC104,528$9.13M0.0%-5.2%0.167%Search for SEC Filing on Google Icon
2/13/2026Wells Fargo & Company MN71,645$6.26M0.0%+49.9%0.115%Search for SEC Filing on Google Icon
2/13/2026Keystone Investors PTE Ltd.26,390$2.31M0.2%N/A0.042%Search for SEC Filing on Google Icon
2/12/2026Brooklyn Investment Group4,331$0.38M0.0%N/A0.007%Search for SEC Filing on Google Icon
2/12/2026Orion Porfolio Solutions LLC4,396$0.38M0.0%-36.5%0.007%Search for SEC Filing on Google Icon
2/12/2026MetLife Investment Management LLC32,440$2.83M0.0%-4.2%0.052%Search for SEC Filing on Google Icon
2/12/2026Cibc World Markets Corp3,851$0.34M0.0%N/A0.006%Search for SEC Filing on Google Icon
2/12/2026Renaissance Technologies LLC8,167$0.71M0.0%N/A0.013%Search for SEC Filing on Google Icon
2/12/2026Dimensional Fund Advisors LP414,415$36.20M0.0%-5.5%0.663%Search for SEC Filing on Google Icon
2/12/2026Ensign Peak Advisors Inc4,486$0.39M0.0%-59.2%0.007%Search for SEC Filing on Google Icon
2/12/2026AlphaCentric Advisors LLC8,549$0.75M0.7%N/A0.014%Search for SEC Filing on Google Icon
2/12/2026Informed Momentum Co LLC78,498$6.86M0.8%-2.0%0.126%Search for SEC Filing on Google Icon
2/12/2026Skandinaviska Enskilda Banken AB publ 205,574$17.96M0.1%+160.9%0.329%Search for SEC Filing on Google Icon
2/12/2026New York State Common Retirement Fund18,382$1.61M0.0%-6.1%0.029%Search for SEC Filing on Google Icon
2/12/2026Campbell & CO Investment Adviser LLC21,054$1.84M0.1%N/A0.034%Search for SEC Filing on Google Icon
2/12/2026Knott David M Jr73,000$6.38M2.9%-12.0%0.117%Search for SEC Filing on Google Icon
2/12/2026Swiss National Bank98,200$8.58M0.0%+2.2%0.157%Search for SEC Filing on Google Icon
2/12/2026Great Lakes Advisors LLC73,966$6.46M0.1%-17.1%0.118%Search for SEC Filing on Google Icon
2/12/2026Aviva PLC5,609$0.49M0.0%-28.0%0.009%Search for SEC Filing on Google Icon
2/12/2026Nuveen LLC125,861$10.99M0.0%-2.0%0.201%Search for SEC Filing on Google Icon
2/11/2026Nationale Nederlanden Powszechne Towarzystwo Emerytalne S.A.571,825$49.94M4.4%N/A0.915%Search for SEC Filing on Google Icon
2/11/2026Illinois Municipal Retirement Fund31,244$2.73M0.0%-5.8%0.050%Search for SEC Filing on Google Icon
2/11/2026Deutsche Bank AG105,460$9.21M0.0%-10.0%0.169%Search for SEC Filing on Google Icon
2/11/2026Axiom Investors LLC DE89,468$7.81M0.1%+11.7%0.143%Search for SEC Filing on Google Icon
2/11/2026Fox Run Management L.L.C.6,654$0.58M0.1%+114.4%0.011%Search for SEC Filing on Google Icon
2/11/2026Cerity Partners LLC9,049$0.79M0.0%+5.0%0.014%Search for SEC Filing on Google Icon
2/11/2026LPL Financial LLC3,265$0.29M0.0%-34.6%0.005%Search for SEC Filing on Google Icon
2/11/2026Franklin Resources Inc.76,442$6.68M0.0%-7.8%0.122%Search for SEC Filing on Google Icon
2/11/2026O Shaughnessy Asset Management LLC4,369$0.38M0.0%N/A0.007%Search for SEC Filing on Google Icon
2/11/2026JPMorgan Chase & Co.155,300$13.56M0.0%-38.5%0.248%Search for SEC Filing on Google Icon
Data available starting January 2016

See Full Table
Protagonist Therapeutics logo
Protagonist Therapeutics, Inc., a biopharmaceutical company, develops peptide-based drugs for hematology and blood disorders, and inflammatory and immunomodulatory diseases. It is developing Rusfertide (PTG-300), an injectable hepcidin mimetic that completed phase 2 clinical trials for the treatment of polycythemia vera and other blood disorders; and JNJ-2113, an orally delivered investigational drug to block biological pathways that completed phase 2b clinical trials for the treatment of moderate-to-severe plaque psoriasis; and PN-943, an orally delivered, gut-restricted alpha 4 beta 7 specific integrin antagonist completed a phase 2 clinical trials in patients with moderate to severe ulcerative colitis. The company has a license and collaboration agreement with Takeda to commercialize rusfertide; and JNJ Innovative Medicines to co-develop Interleukin-23 receptor antagonist compound JNJ-2113. Protagonist Therapeutics, Inc. was incorporated in 2006 and is headquartered in Newark, California.
Read More on Protagonist Therapeutics

Today's Range

Now: $99.00
Low: $98.88
High: $101.80

50 Day Range

MA: $86.80
Low: $79.73
High: $101.68

52 Week Range

Now: $99.00
Low: $39.60
High: $105.69

Volume

534,216 shs

Average Volume

783,519 shs

Market Capitalization

$6.32 billion

P/E Ratio

N/A

Dividend Yield

N/A

Beta

2.23

Who are the company insiders with the largest holdings of Protagonist Therapeutics?

Protagonist Therapeutics' top insider investors include:
  1. Dinesh V Ph D Patel (CEO)
  2. Suneel Gupta (Insider)
  3. Arturo Md Molina (Insider)
  4. Asif Ali (CFO)
  5. William D Waddill (Director)
  6. Lewis T Williams (Director)
Learn More about top insider investors at Protagonist Therapeutics.

Who are the major institutional investors of Protagonist Therapeutics?

Protagonist Therapeutics' top institutional shareholders include:
  1. Farallon Capital Management LLC — 9.83%
  2. Vanguard Group Inc. — 8.66%
  3. RTW Investments LP — 8.09%
  4. State Street Corp — 5.12%
  5. Wellington Management Group LLP — 5.07%
  6. UBS Group AG — 4.43%
Learn More about top institutional investors of Protagonist Therapeutics stock.

Which major investors are selling Protagonist Therapeutics stock?

Within the previous quarter, PTGX stock was sold by these institutional investors:
  1. Jefferies Financial Group Inc.
  2. RTW Investments LP
  3. Commodore Capital LP
  4. Adage Capital Partners GP L.L.C.
  5. Pictet Asset Management Holding SA
  6. Millennium Management LLC
  7. JPMorgan Chase & Co.
  8. Royal Bank of Canada
During the previous year, company insiders that have sold Protagonist Therapeutics company stock include:
  1. Dinesh V Ph D Patel (CEO)
  2. Suneel Gupta (Insider)
  3. Arturo Md Molina (Insider)
  4. Asif Ali (CFO)
  5. William D Waddill (Director)
Learn More investors selling Protagonist Therapeutics stock.

Which major investors are buying Protagonist Therapeutics stock?

Within the last quarter, PTGX stock was bought by institutional investors including:
  1. Janus Henderson Group PLC
  2. Wellington Management Group LLP
  3. Vanguard Group Inc.
  4. UBS Group AG
  5. Nationale Nederlanden Powszechne Towarzystwo Emerytalne S.A.
  6. Invesco Ltd.
  7. Clearbridge Investments LLC
  8. Jennison Associates LLC