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PTGX Insider Trading

Insider Ownership Percentage: 4.90%
Insider Buying (Last 12 Months): $0.00
Insider Selling (Last 12 Months): $9,160,103.66

Protagonist Therapeutics Insider Trading History Chart

This chart shows the insider buying and selling history at Protagonist Therapeutics by year and by quarter.

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Protagonist Therapeutics Share Price & Price History

Current Price: $87.33
Price Change: ▲ Price Increase of +1.26 (1.46%)
As of 12/4/2025 05:00 PM ET

This chart shows the closing price history over time for PTGX up to the past year.

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Days: 30 | 90 | 365

Protagonist Therapeutics Insider Trading History

Transaction DateInsider NameTitleBuy/SellNumber of SharesAverage Share PriceTotal TransactionShares Held After TransactionDetails
10/10/2025William D. WaddillDirectorSell12,000$81.62$979,440.005,130View SEC Filing Icon  
9/22/2025William D. WaddillDirectorSell4,000$64.25$257,000.005,130View SEC Filing Icon  
8/27/2025William D. WaddillDirectorSell4,000$59.25$237,000.009,130View SEC Filing Icon  
7/25/2025Dinsesh V. PatelCEOSell10,415$54.78$570,533.70520,603View SEC Filing Icon  
7/23/2025Dinsesh V. PatelCEOSell17,520$54.79$959,920.80531,018View SEC Filing Icon  
7/22/2025Dinsesh V. PatelCEOSell22,065$55.05$1,214,678.25548,538View SEC Filing Icon  
7/21/2025Dinsesh V. PatelCEOSell12,859$54.86$705,444.74570,603View SEC Filing Icon  
6/10/2025Arturo MolinaInsiderSell10,000$57.03$570,300.0083,892View SEC Filing Icon  
4/22/2025Asif AliCFOSell1,756$46.00$80,776.0061,065View SEC Filing Icon  
3/17/2025William D. WaddillDirectorSell4,000$54.25$217,000.0013,130View SEC Filing Icon  
3/13/2025Arturo MolinaInsiderSell30,514$55.74$1,700,850.3683,892View SEC Filing Icon  
3/12/2025Asif AliCFOSell24,903$58.73$1,462,553.1962,821View SEC Filing Icon  
2/19/2025Dinsesh V. PatelCEOSell5,359$38.18$204,606.62540,260View SEC Filing Icon  
11/27/2024Arturo MolinaInsiderSell26,000$44.70$1,162,200.0046,444View SEC Filing Icon  
11/25/2024Dinsesh V. PatelCEOSell78,520$46.96$3,687,299.20435,208View SEC Filing Icon  
11/25/2024Suneel GuptaInsiderSell103,437$46.04$4,762,239.48256,174View SEC Filing Icon  
11/15/2024Arturo MolinaInsiderSell1,906$40.98$78,107.8846,444View SEC Filing Icon  
9/11/2024Asif AliCFOSell14,203$44.49$631,891.4734,960View SEC Filing Icon  
9/10/2024William D. WaddillDirectorSell8,000$45.00$360,000.0012,000View SEC Filing Icon  
7/24/2024William D. WaddillDirectorSell8,000$40.00$320,000.0012,000View SEC Filing Icon  
6/7/2024Dinsesh V. PatelCEOSell35,000$35.19$1,231,650.00515,415View SEC Filing Icon  
6/7/2024William D. WaddillDirectorSell8,000$35.00$280,000.0012,000View SEC Filing Icon  
4/18/2024Asif AliCFOSell1,234$25.11$30,985.7437,163View SEC Filing Icon  
4/1/2024Dinsesh V. PatelCEOSell25,000$28.31$707,750.00549,590View SEC Filing Icon  
3/1/2024Asif AliCFOSell14,248$32.24$459,355.5238,397View SEC Filing Icon  
3/1/2024Dinsesh V. PatelCEOSell30,000$31.62$948,600.00574,590View SEC Filing Icon  
3/1/2024William D. WaddillDirectorSell12,975$31.34$406,636.5012,000View SEC Filing Icon  
1/9/2024Suneel GuptaInsiderSell5,000$25.00$125,000.00187,567View SEC Filing Icon  
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SEC Filings (Institutional Ownership Changes) for Protagonist Therapeutics (NASDAQ:PTGX)

98.63% of Protagonist Therapeutics stock is owned by institutions. Institutional ownership can be a sign of analyst confidence in the fundamentals of the stock.

Institutional Buying and Selling by Quarter

This chart shows the instiutional buying and selling at PTGX by year and by quarter.

Skip Institutional Buying and Selling Chart and Table DataRead Chart Data in Institutional Trading History Table

Protagonist Therapeutics Institutional Trading History

Reporting DateHedge FundShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
12/1/2025Cambria Investment Management L.P.10,944$0.73M0.0%+25.0%0.018%Search for SEC Filing on Google Icon
11/21/2025CIBC Bancorp USA Inc.6,205$0.41M0.0%N/A0.010%Search for SEC Filing on Google Icon
11/17/2025CANADA LIFE ASSURANCE Co48,407$3.15M0.0%-3.7%0.077%Search for SEC Filing on Google Icon
11/17/2025Woodline Partners LP1,438,247$95.54M0.4%+51.9%2.300%Search for SEC Filing on Google Icon
11/17/2025Wexford Capital LP941$63K0.0%-71.6%0.002%Search for SEC Filing on Google Icon
11/17/2025Parkman Healthcare Partners LLC61,849$4.11M0.4%+0.4%0.099%Search for SEC Filing on Google Icon
11/17/2025Northwestern Mutual Wealth Management Co.58,894$3.91M0.0%-25.4%0.094%Search for SEC Filing on Google Icon
11/17/2025Mariner LLC13,551$0.90M0.0%-13.7%0.022%Search for SEC Filing on Google Icon
11/17/2025Millennium Management LLC127,560$8.47M0.0%+739.7%0.204%Search for SEC Filing on Google Icon
11/17/2025MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.30,871$2.05M0.0%-13.9%0.049%Search for SEC Filing on Google Icon
11/17/2025Jain Global LLC14,850$0.99M0.0%N/A0.024%Search for SEC Filing on Google Icon
11/17/2025HighVista Strategies LLC121,682$8.08M2.0%+110.3%0.195%Search for SEC Filing on Google Icon
11/17/2025Gotham Asset Management LLC22,198$1.48M0.0%-40.5%0.036%Search for SEC Filing on Google Icon
11/17/2025Farallon Capital Management LLC6,196,006$411.60M1.7%+0.4%9.910%Search for SEC Filing on Google Icon
11/17/2025Focus Partners Wealth448,988$29.83M0.0%N/A0.718%Search for SEC Filing on Google Icon
11/17/2025Boxer Capital Management LLC110,000$7.31M2.3%+83.3%0.176%Search for SEC Filing on Google Icon
11/17/2025Brevan Howard Capital Management LP7,598$0.51M0.0%-71.9%0.012%Search for SEC Filing on Google Icon
11/17/2025Commodore Capital LP1,025,000$68.09M3.3%-4.7%1.639%Search for SEC Filing on Google Icon
11/17/2025Bank of America Corp DE829,877$55.13M0.0%-2.6%1.327%Search for SEC Filing on Google Icon
11/17/2025Alliancebernstein L.P.260,854$17.33M0.0%+284.2%0.417%Search for SEC Filing on Google Icon
11/17/2025Ameriprise Financial Inc.153,191$10.18M0.0%-9.0%0.245%Search for SEC Filing on Google Icon
11/14/2025Schonfeld Strategic Advisors LLC95,190$6.32M0.0%+23.5%0.152%Search for SEC Filing on Google Icon
11/14/2025Creative Planning36,214$2.41M0.0%+19.9%0.058%Search for SEC Filing on Google Icon
11/14/2025SummitTX Capital L.P.31,490$2.09M0.1%N/A0.050%Search for SEC Filing on Google Icon
11/14/2025Raymond James Financial Inc.294,296$19.55M0.0%-5.7%0.471%Search for SEC Filing on Google Icon
11/14/2025Bellevue Group AG20,581$1.37M0.0%+5.7%0.033%Search for SEC Filing on Google Icon
11/14/2025Deep Track Capital LP1,715,691$113.97M3.2%-47.1%2.744%Search for SEC Filing on Google Icon
11/14/2025California State Teachers Retirement System47,437$3.15M0.0%-7.3%0.076%Search for SEC Filing on Google Icon
11/14/2025Duquesne Family Office LLC159,700$10.61M0.3%N/A0.255%Search for SEC Filing on Google Icon
11/14/2025ADAR1 Capital Management LLC989,182$65.71M6.2%+4.3%1.582%Search for SEC Filing on Google Icon
11/14/2025UBS AM A Distinct Business Unit of UBS Asset Management Americas LLC110,229$7.32M0.0%-54.7%0.176%Search for SEC Filing on Google Icon
11/14/2025Vident Advisory LLC5,070$0.34M0.0%N/A0.008%Search for SEC Filing on Google Icon
11/14/2025Mangrove Partners IM LLC478,413$31.78M2.6%+21.0%0.765%Search for SEC Filing on Google Icon
11/14/2025iSAM Funds UK Ltd3,118$0.21M0.0%N/A0.005%Search for SEC Filing on Google Icon
11/14/2025Wellington Management Group LLP1,908,446$126.78M0.0%+83.9%3.053%Search for SEC Filing on Google Icon
11/14/2025Comerica Bank16,395$1.09M0.0%-23.0%0.026%Search for SEC Filing on Google Icon
11/14/2025FORA Capital LLC3,685$0.25M0.0%N/A0.006%Search for SEC Filing on Google Icon
11/14/2025Glenmede Investment Management LP18,000$1.20M0.0%-16.0%0.029%Search for SEC Filing on Google Icon
11/13/2025Lynx1 Capital Management LP700,014$46.50M8.8%-4.5%1.120%Search for SEC Filing on Google Icon
11/13/2025Marshall Wace LLP1,085,564$72.11M0.1%N/A1.736%Search for SEC Filing on Google Icon
11/13/2025Kennedy Capital Management LLC208,437$13.85M0.3%+54.5%0.333%Search for SEC Filing on Google Icon
11/13/2025Certuity LLC4,535$0.30M0.0%N/A0.007%Search for SEC Filing on Google Icon
11/13/2025Invesco Ltd.1,003,706$66.68M0.0%+39.1%1.605%Search for SEC Filing on Google Icon
11/13/2025Sei Investments Co.44,011$2.92M0.0%-2.0%0.070%Search for SEC Filing on Google Icon
11/13/2025UBS Group AG1,896,008$125.95M0.0%-24.2%3.033%Search for SEC Filing on Google Icon
11/13/2025Atika Capital Management LLC83,000$5.51M0.4%N/A0.133%Search for SEC Filing on Google Icon
11/13/2025Capital Fund Management S.A.20,348$1.35M0.0%-59.1%0.033%Search for SEC Filing on Google Icon
11/13/2025Mackenzie Financial Corp4,064$0.27M0.0%-81.9%0.007%Search for SEC Filing on Google Icon
11/13/2025Franklin Resources Inc.82,918$5.51M0.0%+0.4%0.133%Search for SEC Filing on Google Icon
11/13/2025Quadrant Capital Group LLC1,352$90K0.0%N/A0.002%Search for SEC Filing on Google Icon
11/13/2025Legal & General Group Plc155,829$10.35M0.0%-6.2%0.249%Search for SEC Filing on Google Icon
11/13/2025Vestcor Inc5,022$0.33M0.0%N/A0.008%Search for SEC Filing on Google Icon
11/13/2025Swiss National Bank96,100$6.38M0.0%+2.5%0.154%Search for SEC Filing on Google Icon
11/13/2025WINTON GROUP Ltd18,561$1.23M0.0%+6.5%0.030%Search for SEC Filing on Google Icon
11/13/2025Russell Investments Group Ltd.5,924$0.39M0.0%+4,492.2%0.009%Search for SEC Filing on Google Icon
11/13/2025Jefferies Financial Group Inc.821,503$54.57M0.3%-0.3%1.314%Search for SEC Filing on Google Icon
11/13/2025Natixis Advisors LLC16,855$1.12M0.0%+25.4%0.027%Search for SEC Filing on Google Icon
11/13/2025First Trust Advisors LP62,724$4.17M0.0%-44.9%0.100%Search for SEC Filing on Google Icon
11/13/2025Knott David M Jr83,000$5.51M2.2%+3.8%0.133%Search for SEC Filing on Google Icon
11/12/2025Barclays PLC171,406$11.39M0.0%-19.2%0.274%Search for SEC Filing on Google Icon
11/12/2025Orion Porfolio Solutions LLC6,928$0.46M0.0%+5.0%0.011%Search for SEC Filing on Google Icon
11/12/2025Dimensional Fund Advisors LP438,515$29.13M0.0%+143.6%0.701%Search for SEC Filing on Google Icon
11/12/2025Teachers Retirement System of The State of Kentucky17,296$1.15M0.0%-7.7%0.028%Search for SEC Filing on Google Icon
11/12/2025Victory Capital Management Inc.85,494$5.68M0.0%-6.0%0.137%Search for SEC Filing on Google Icon
11/12/2025Segall Bryant & Hamill LLC123,125$8.18M0.1%+2.5%0.197%Search for SEC Filing on Google Icon
11/12/2025Royce & Associates LP16,989$1.13M0.0%+38.6%0.027%Search for SEC Filing on Google Icon
11/12/2025American Century Companies Inc.600,047$39.86M0.0%-26.3%0.960%Search for SEC Filing on Google Icon
11/12/2025Rafferty Asset Management LLC74,827$4.97M0.0%-7.1%0.120%Search for SEC Filing on Google Icon
11/12/2025Quantbot Technologies LP3,303$0.22M0.0%N/A0.005%Search for SEC Filing on Google Icon
11/12/2025Handelsbanken Fonder AB18,900$1.26M0.0%+11.2%0.030%Search for SEC Filing on Google Icon
11/12/2025Intech Investment Management LLC21,643$1.44M0.0%-36.3%0.035%Search for SEC Filing on Google Icon
11/12/2025US Bancorp DE5,852$0.39M0.0%+12.0%0.009%Search for SEC Filing on Google Icon
11/12/2025Fox Run Management L.L.C.3,103$0.21M0.0%N/A0.005%Search for SEC Filing on Google Icon
11/10/2025TD Asset Management Inc150,428$9.99M0.0%+29.3%0.241%Search for SEC Filing on Google Icon
11/10/2025Palumbo Wealth Management LLC5,268$0.35M0.1%-30.0%0.008%Search for SEC Filing on Google Icon
11/10/2025EverSource Wealth Advisors LLC540$36K0.0%+138.9%0.001%Search for SEC Filing on Google Icon
11/10/2025Ameritas Investment Partners Inc.4,863$0.32M0.0%-17.7%0.008%Search for SEC Filing on Google Icon
11/10/2025Citigroup Inc.152,580$10.14M0.0%+95.7%0.244%Search for SEC Filing on Google Icon
11/10/2025China Universal Asset Management Co. Ltd.15,905$1.06M0.1%-15.9%0.025%Search for SEC Filing on Google Icon
11/10/2025Persistent Asset Partners Ltd11,780$0.78M0.5%-32.8%0.019%Search for SEC Filing on Google Icon
11/7/2025GSA Capital Partners LLP5,884$0.39M0.0%N/A0.009%Search for SEC Filing on Google Icon
11/7/2025Skandinaviska Enskilda Banken AB publ 78,796$5.23M0.0%-4.8%0.127%Search for SEC Filing on Google Icon
11/7/2025Vanguard Group Inc.4,257,229$282.81M0.0%-2.3%6.843%Search for SEC Filing on Google Icon
11/7/2025JPMorgan Chase & Co.252,400$16.77M0.0%-42.6%0.406%Search for SEC Filing on Google Icon
11/7/2025State of New Jersey Common Pension Fund D37,956$2.52M0.0%-7.5%0.061%Search for SEC Filing on Google Icon
11/7/2025PNC Financial Services Group Inc.2,738$0.18M0.0%+13.4%0.004%Search for SEC Filing on Google Icon
11/7/2025GF Fund Management CO. LTD.1,338$89K0.0%-12.3%0.002%Search for SEC Filing on Google Icon
11/6/2025Abich Financial Wealth Management LLC932$62K0.0%N/A0.001%Search for SEC Filing on Google Icon
11/6/2025Public Sector Pension Investment Board228,146$15.16M0.1%+8.0%0.367%Search for SEC Filing on Google Icon
11/6/2025Illinois Municipal Retirement Fund33,183$2.20M0.0%+20.4%0.053%Search for SEC Filing on Google Icon
11/6/2025Cornerstone Investment Partners LLC4,632$0.31M0.0%-7.0%0.007%Search for SEC Filing on Google Icon
11/6/2025Caprock Group LLC5,802$0.39M0.0%N/A0.009%Search for SEC Filing on Google Icon
11/6/2025Rhumbline Advisers163,980$10.89M0.0%-5.2%0.264%Search for SEC Filing on Google Icon
11/6/2025Baader Bank Aktiengesellschaft4,300$0.29M0.0%N/A0.007%Search for SEC Filing on Google Icon
11/6/2025Profund Advisors LLC18,157$1.21M0.0%-4.8%0.029%Search for SEC Filing on Google Icon
11/6/2025ProShare Advisors LLC13,187$0.88M0.0%-14.2%0.021%Search for SEC Filing on Google Icon
11/5/2025Smartleaf Asset Management LLC1,403$91K0.0%+11.6%0.002%Search for SEC Filing on Google Icon
11/5/2025Alps Advisors Inc.29,203$1.94M0.0%-27.4%0.047%Search for SEC Filing on Google Icon
11/5/2025Bessemer Group Inc.4,275$0.28M0.0%+748.2%0.007%Search for SEC Filing on Google Icon
11/5/2025Envestnet Asset Management Inc.24,258$1.61M0.0%+1.6%0.039%Search for SEC Filing on Google Icon
Data available starting January 2016

See Full Table
Protagonist Therapeutics logo
Protagonist Therapeutics, Inc., a biopharmaceutical company, develops peptide-based drugs for hematology and blood disorders, and inflammatory and immunomodulatory diseases. It is developing Rusfertide (PTG-300), an injectable hepcidin mimetic that completed phase 2 clinical trials for the treatment of polycythemia vera and other blood disorders; and JNJ-2113, an orally delivered investigational drug to block biological pathways that completed phase 2b clinical trials for the treatment of moderate-to-severe plaque psoriasis; and PN-943, an orally delivered, gut-restricted alpha 4 beta 7 specific integrin antagonist completed a phase 2 clinical trials in patients with moderate to severe ulcerative colitis. The company has a license and collaboration agreement with Takeda to commercialize rusfertide; and JNJ Innovative Medicines to co-develop Interleukin-23 receptor antagonist compound JNJ-2113. Protagonist Therapeutics, Inc. was incorporated in 2006 and is headquartered in Newark, California.
Read More on Protagonist Therapeutics

Today's Range

Now: $87.33
Low: $85.13
High: $88.10

50 Day Range

MA: $78.32
Low: $64.00
High: $90.07

52 Week Range

Now: $87.33
Low: $33.70
High: $93.25

Volume

736,770 shs

Average Volume

862,927 shs

Market Capitalization

$5.46 billion

P/E Ratio

140.86

Dividend Yield

N/A

Beta

2.19

Who are the company insiders with the largest holdings of Protagonist Therapeutics?

Protagonist Therapeutics' top insider investors include:
  1. Dinesh V Ph D Patel (CEO)
  2. Suneel Gupta (Insider)
  3. Arturo Md Molina (Insider)
  4. Asif Ali (CFO)
  5. William D Waddill (Director)
Learn More about top insider investors at Protagonist Therapeutics.

Who are the major institutional investors of Protagonist Therapeutics?

Protagonist Therapeutics' top institutional shareholders include:
  1. Farallon Capital Management LLC — 9.91%
  2. Vanguard Group Inc. — 6.84%
  3. Wellington Management Group LLP — 3.05%
  4. UBS Group AG — 3.03%
  5. Deep Track Capital LP — 2.74%
  6. Woodline Partners LP — 2.30%
Learn More about top institutional investors of Protagonist Therapeutics stock.

Which major investors are selling Protagonist Therapeutics stock?

Within the previous quarter, PTGX stock was sold by these institutional investors:
  1. Deep Track Capital LP
  2. UBS Group AG
  3. American Century Companies Inc.
  4. JPMorgan Chase & Co.
  5. UBS AM A Distinct Business Unit of UBS Asset Management Americas LLC
  6. Vanguard Group Inc.
  7. Susquehanna International Group LLP
  8. First Trust Advisors LP
During the previous year, company insiders that have sold Protagonist Therapeutics company stock include:
  1. Dinesh V Ph D Patel (CEO)
  2. Suneel Gupta (Insider)
  3. Arturo Md Molina (Insider)
  4. Asif Ali (CFO)
Learn More investors selling Protagonist Therapeutics stock.

Which major investors are buying Protagonist Therapeutics stock?

Within the last quarter, PTGX stock was bought by institutional investors including:
  1. Marshall Wace LLP
  2. Wellington Management Group LLP
  3. Woodline Partners LP
  4. Focus Partners Wealth
  5. Invesco Ltd.
  6. Dimensional Fund Advisors LP
  7. Alliancebernstein L.P.
  8. Duquesne Family Office LLC