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PLX Insider Trading

Insider Ownership Percentage: 6.50%
Insider Buying (Last 12 Months): $307,760.00
Insider Selling (Last 12 Months): $628.32

Protalix BioTherapeutics Insider Trading History Chart

This chart shows the insider buying and selling history at Protalix BioTherapeutics by year and by quarter.

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Protalix BioTherapeutics Share Price & Price History

Current Price: $3.00
Price Change: ▼ Price Decrease of -0.14 (-4.46%)
As of 02/24/2026 05:00 PM ET

This chart shows the closing price history over time for PLX up to the past year.

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Days: 30 | 90 | 365

Protalix BioTherapeutics Insider Trading History

Transaction DateInsider NameTitleBuy/SellNumber of SharesAverage Share PriceTotal TransactionShares Held After TransactionDetails
12/19/2025Dror BashanCEOBuy56,000$1.81$101,360.00188,516View SEC Filing Icon  
11/18/2025Amos Bar-ShalevDirectorSell168$1.87$314.16View SEC Filing Icon  
11/18/2025Amos Bar-ShalevDirectorSell168$1.87$314.16View SEC Filing Icon  
6/10/2025Aharon SchwartzDirectorBuy129,000$1.60$206,400.00303,000View SEC Filing Icon  
10/19/2023Dror BashanCEOBuy64,516$1.40$90,322.40132,516View SEC Filing Icon  
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SEC Filings (Institutional Ownership Changes) for Protalix BioTherapeutics (NYSE:PLX)

16.53% of Protalix BioTherapeutics stock is owned by institutions. Institutional ownership can be a sign of analyst confidence in the fundamentals of the stock.

Institutional Buying and Selling by Quarter

This chart shows the instiutional buying and selling at PLX by year and by quarter.

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Protalix BioTherapeutics Institutional Trading History

Reporting DateHedge FundShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
2/19/2026Invesco Ltd.50,563$91K0.0%+12.4%0.063%Search for SEC Filing on Google Icon
2/18/2026XTX Topco Ltd34,296$62K0.0%-60.0%0.043%Search for SEC Filing on Google Icon
2/18/2026Opaleye Management Inc.2,478,176$4.46M0.6%-4.0%3.082%Search for SEC Filing on Google Icon
2/18/2026Main Street Financial Solutions LLC214,100$0.39M0.0%+65.8%0.266%Search for SEC Filing on Google Icon
2/17/2026Lazard Asset Management LLC71,393$0.13M0.0%N/A0.089%Search for SEC Filing on Google Icon
2/16/2026Barclays PLC112,849$0.20M0.0%+10.9%0.140%Search for SEC Filing on Google Icon
2/13/2026Marshall Wace LLP19,079$34K0.0%N/A0.024%Search for SEC Filing on Google Icon
2/13/2026The Manufacturers Life Insurance Company 18,498$33K0.0%-23.1%0.023%Search for SEC Filing on Google Icon
2/13/2026Smartleaf Asset Management LLC25,975$45K0.0%N/A0.032%Search for SEC Filing on Google Icon
2/13/2026State Street Corp585,261$1.05M0.0%+17.4%0.728%Search for SEC Filing on Google Icon
2/13/2026Wells Fargo & Company MN79,002$0.14M0.0%+84.5%0.098%Search for SEC Filing on Google Icon
2/12/2026Jane Street Group LLC289,917$0.52M0.0%-894.3%0.360%Search for SEC Filing on Google Icon
2/12/2026HRT Financial LP64,610$0.12M0.0%N/A0.080%Search for SEC Filing on Google Icon
2/12/2026Renaissance Technologies LLC1,263,300$2.27M0.0%-4.0%1.571%Search for SEC Filing on Google Icon
2/12/2026Dimensional Fund Advisors LP28,744$51K0.0%+68.8%0.036%Search for SEC Filing on Google Icon
2/12/2026New York State Common Retirement Fund31,100$56K0.0%-24.7%0.039%Search for SEC Filing on Google Icon
2/10/2026Goldman Sachs Group Inc.262,809$0.47M0.0%+74.2%0.327%Search for SEC Filing on Google Icon
2/9/2026Geode Capital Management LLC830,054$1.49M0.0%+1.3%1.032%Search for SEC Filing on Google Icon
1/30/2026R Squared Ltd14,632$26K0.0%N/A0.018%Search for SEC Filing on Google Icon
1/27/2026Round Rock Advisors LLC155,102$0.28M0.0%N/A0.193%Search for SEC Filing on Google Icon
1/23/2026State of Alaska Department of Revenue21,831$39K0.0%N/A0.027%Search for SEC Filing on Google Icon
1/9/2026SG Americas Securities LLC17,155$31K0.0%N/A0.021%Search for SEC Filing on Google Icon
11/17/2025Prelude Capital Management LLC49,791$0.11M0.0%-11.2%0.062%Search for SEC Filing on Google Icon
11/17/2025MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.32,253$72K0.0%-15.3%0.040%Search for SEC Filing on Google Icon
11/14/2025Virtu Financial LLC16,530$37K0.0%N/A0.021%Search for SEC Filing on Google Icon
11/13/2025BNP Paribas Financial Markets15,215$34K0.0%+126.5%0.019%Search for SEC Filing on Google Icon
11/12/2025Dimensional Fund Advisors LP17,028$38K0.0%-62.6%0.021%Search for SEC Filing on Google Icon
11/12/2025Intech Investment Management LLC31,248$69K0.0%-14.4%0.039%Search for SEC Filing on Google Icon
11/6/2025Rhumbline Advisers65,194$0.15M0.0%-6.6%0.082%Search for SEC Filing on Google Icon
11/6/2025Stratos Wealth Partners LTD.500,000$1.11M0.0%+42.9%0.627%Search for SEC Filing on Google Icon
11/4/2025State of Wyoming39,018$87K0.0%N/A0.049%Search for SEC Filing on Google Icon
11/3/2025New York State Common Retirement Fund41,300$92K0.0%-40.1%0.052%Search for SEC Filing on Google Icon
8/16/2025Evergreen Capital Management LLC171,338$0.25M0.0%N/A0.215%Search for SEC Filing on Google Icon
8/15/2025Bank of America Corp DE21,892$32K0.0%+364,766.7%0.028%Search for SEC Filing on Google Icon
8/14/2025MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.38,075$56K0.0%N/A0.048%Search for SEC Filing on Google Icon
8/13/2025Diametric Capital LP143,272$0.21M0.1%N/A0.180%Search for SEC Filing on Google Icon
8/13/2025Invesco Ltd.45,141$67K0.0%N/A0.057%Search for SEC Filing on Google Icon
8/13/2025New York State Common Retirement Fund69,000$0.10M0.0%N/A0.087%Search for SEC Filing on Google Icon
8/12/2025XTX Topco Ltd73,675$0.11M0.0%+76.1%0.093%Search for SEC Filing on Google Icon
8/12/2025JPMorgan Chase & Co.34,545$51K0.0%+2,065.8%0.043%Search for SEC Filing on Google Icon
8/8/2025Intech Investment Management LLC36,490$54K0.0%N/A0.046%Search for SEC Filing on Google Icon
8/8/2025Police & Firemen s Retirement System of New Jersey18,554$27K0.0%N/A0.023%Search for SEC Filing on Google Icon
8/8/2025Geode Capital Management LLC826,333$1.22M0.0%N/A1.038%Search for SEC Filing on Google Icon
8/7/2025Cascade Financial Partners LLC17,000$25K0.0%N/A0.021%Search for SEC Filing on Google Icon
8/7/2025Connor Clark & Lunn Investment Management Ltd.496,216$0.73M0.0%+2.8%0.623%Search for SEC Filing on Google Icon
8/5/2025Harel Insurance Investments & Financial Services Ltd.26,000$40K0.0%N/A0.033%Search for SEC Filing on Google Icon
7/29/2025Orin Green Financial LLC61,200$91K0.0%+22.4%0.077%Search for SEC Filing on Google Icon
6/27/2025Goldman Sachs Group Inc.289,461$0.74M0.0%+482.3%0.364%Search for SEC Filing on Google Icon
5/19/2025Jane Street Group LLC294,318$0.75M0.0%+159.0%0.370%Search for SEC Filing on Google Icon
5/16/2025Goldman Sachs Group Inc.289,461$0.74M0.0%+482.3%0.364%Search for SEC Filing on Google Icon
5/16/2025NewEdge Advisors LLC15,080$39K0.0%N/A0.019%Search for SEC Filing on Google Icon
5/15/2025Cubist Systematic Strategies LLC53,380$0.14M0.0%+82.1%0.067%Search for SEC Filing on Google Icon
5/15/2025OMERS ADMINISTRATION Corp179,300$0.46M0.0%N/A0.225%Search for SEC Filing on Google Icon
5/14/2025Hsbc Holdings PLC25,535$64K0.0%-36.2%0.032%Search for SEC Filing on Google Icon
5/12/2025Connor Clark & Lunn Investment Management Ltd.482,875$1.24M0.0%N/A0.607%Search for SEC Filing on Google Icon
5/8/2025XTX Topco Ltd41,826$0.11M0.0%N/A0.053%Search for SEC Filing on Google Icon
5/8/2025GSA Capital Partners LLP209,292$0.54M0.0%-31.5%0.263%Search for SEC Filing on Google Icon
5/6/2025Orin Green Financial LLC50,000$0.13M0.1%-30.6%0.063%Search for SEC Filing on Google Icon
4/30/2025Stratos Wealth Partners LTD.346,400$0.89M0.0%+28.3%0.444%Search for SEC Filing on Google Icon
2/17/2025Squarepoint Ops LLC73,940$0.14M0.0%+33.4%0.100%Search for SEC Filing on Google Icon
2/17/2025Point72 Asia Singapore Pte. Ltd.53,507$0.10M0.0%+13.7%0.073%Search for SEC Filing on Google Icon
2/17/2025Millennium Management LLC387,921$0.73M0.0%+3.8%0.527%Search for SEC Filing on Google Icon
2/17/2025Cubist Systematic Strategies LLC29,307$55K0.0%+24.1%0.040%Search for SEC Filing on Google Icon
2/17/2025Bank of America Corp DE33,714$63K0.0%-25.1%0.046%Search for SEC Filing on Google Icon
2/14/2025Jane Street Group LLC113,616$0.21M0.0%+147.2%0.154%Search for SEC Filing on Google Icon
2/14/2025Northern Trust Corp731,742$1.38M0.0%+1,299.4%0.994%Search for SEC Filing on Google Icon
2/13/2025Marshall Wace LLP101,899$0.19M0.0%N/A0.138%Search for SEC Filing on Google Icon
2/13/2025Renaissance Technologies LLC1,118,000$2.10M0.0%+17.0%1.518%Search for SEC Filing on Google Icon
2/11/2025Prudential Financial Inc.36,400$68K0.0%N/A0.049%Search for SEC Filing on Google Icon
2/11/2025Virtu Financial LLC34,276$64K0.0%-21.0%0.047%Search for SEC Filing on Google Icon
2/4/2025Y Intercept Hong Kong Ltd18,818$35K0.0%N/A0.026%Search for SEC Filing on Google Icon
1/22/2025PFG Investments LLC20,730$39K0.0%N/A0.028%Search for SEC Filing on Google Icon
11/25/2024Sanctuary Advisors LLC37,100$38K0.0%N/A0.050%Search for SEC Filing on Google Icon
11/20/2024Virtu Financial LLC43,388$44K0.0%N/A0.059%Search for SEC Filing on Google Icon
11/15/2024XTX Topco Ltd35,058$36K0.0%N/A0.048%Search for SEC Filing on Google Icon
11/15/2024Jane Street Group LLC45,952$47K0.0%-84.2%0.062%Search for SEC Filing on Google Icon
11/15/2024Point72 Asia Singapore Pte. Ltd.47,073$48K0.0%-30.9%0.064%Search for SEC Filing on Google Icon
11/5/2024GSA Capital Partners LLP435,213$0.44M0.0%+8.5%0.592%Search for SEC Filing on Google Icon
9/16/2024Cubist Systematic Strategies LLC32,031$37K0.0%N/A0.044%Search for SEC Filing on Google Icon
9/16/2024Point72 Asia Singapore Pte. Ltd.68,163$80K0.0%N/A0.093%Search for SEC Filing on Google Icon
8/15/2024AQR Capital Management LLC57,106$67K0.0%N/A0.078%Search for SEC Filing on Google Icon
8/15/2024Point72 Asia Singapore Pte. Ltd.68,163$80K0.0%N/A0.093%Search for SEC Filing on Google Icon
8/14/2024Squarepoint Ops LLC137,764$0.16M0.0%+673.3%0.188%Search for SEC Filing on Google Icon
8/14/2024Cubist Systematic Strategies LLC32,031$37K0.0%N/A0.044%Search for SEC Filing on Google Icon
8/9/2024Renaissance Technologies LLC804,600$0.94M0.0%-2.4%1.097%Search for SEC Filing on Google Icon
8/8/2024Ground Swell Capital LLC62,234$73K0.1%N/A0.085%Search for SEC Filing on Google Icon
5/20/2024Virtu Financial LLC157,516$0.20M0.0%N/A0.215%Search for SEC Filing on Google Icon
5/7/2024SG Americas Securities LLC21,467$27K0.0%-38.0%0.029%Search for SEC Filing on Google Icon
5/3/2024GSA Capital Partners LLP493,571$0.62M0.0%-9.3%0.673%Search for SEC Filing on Google Icon
2/2/2024Bailard Inc.68,100$0.12M0.0%N/A0.095%Search for SEC Filing on Google Icon
1/19/2024Denali Advisors LLC94,700$0.17M0.1%-14.1%0.132%Search for SEC Filing on Google Icon
11/15/2023GSA Capital Partners LLP496,781$0.83M0.1%N/A0.694%Search for SEC Filing on Google Icon
11/13/2023Connor Clark & Lunn Investment Management Ltd.167,536$0.28M0.0%+45.0%0.234%Search for SEC Filing on Google Icon
11/7/2023Barclays PLC46,511$77K0.0%+251.6%0.065%Search for SEC Filing on Google Icon
10/27/2023Allspring Global Investments Holdings LLC137,906$0.23M0.0%N/A0.193%Search for SEC Filing on Google Icon
10/24/2023Bank of New York Mellon Corp165,680$0.28M0.0%+12.8%0.231%Search for SEC Filing on Google Icon
10/13/2023SG Americas Securities LLC30,008$50K0.0%N/A0.042%Search for SEC Filing on Google Icon
9/21/2023Barclays PLC13,230$26K0.0%+561.5%0.018%Search for SEC Filing on Google Icon
8/11/2023Natixis132,000$0.26M0.0%N/A0.202%Search for SEC Filing on Google Icon
8/4/2023American International Group Inc.27,034$54K0.0%N/A0.041%Search for SEC Filing on Google Icon
Data available starting January 2016

See Full Table
Protalix BioTherapeutics logo
Protalix BioTherapeutics, Inc., a biopharmaceutical company, engages in the development, production, and commercialization of recombinant therapeutic proteins based on its proprietary ProCellEx plant cell-based protein expression system in the United States, Australia, Canada, Israel, Brazil, Russia, Turkey, and internationally. The company offers Elelyso for the treatment of Gaucher disease; and Elfabrio for the treatment of adult patients with a confirmed diagnosis of Fabry disease. It is also developing PRX-115, a plant cell-expressed recombinant PEGylated Uricase which is in Phase I trial for the treatment of gout; and PRX-119, a plant cell-expressed PEGylated recombinant human DNase I product candidate that is in preclinical phase for the treatment of NETs-related diseases. The company has agreements and partnerships with Pfizer; Fundação Oswaldo Cruz; and Chiesi Farmaceutici S.p.A. The company was incorporated in 1993 and is headquartered in Karmiel, Israel. Protalix BioTherapeutics, Inc. is a subsidiary of Protalix Ltd.
Read More on Protalix BioTherapeutics

Today's Range

Now: $3.00
Low: $2.99
High: $3.17

50 Day Range

MA: $2.27
Low: $1.73
High: $3.15

52 Week Range

Now: $3.00
Low: $1.32
High: $3.19

Volume

2,836,270 shs

Average Volume

1,434,971 shs

Market Capitalization

$241.26 million

P/E Ratio

N/A

Dividend Yield

N/A

Beta

N/A

Who are the company insiders with the largest holdings of Protalix BioTherapeutics?

Protalix BioTherapeutics' top insider investors include:
  1. Aharon Schwartz (Director)
  2. Dror Bashan (CEO)
  3. Amos Bar-Shalev (Director)
Learn More about top insider investors at Protalix BioTherapeutics.

Who are the major institutional investors of Protalix BioTherapeutics?

Protalix BioTherapeutics' top institutional shareholders include:
  1. Opaleye Management Inc. — 3.08%
  2. Renaissance Technologies LLC — 1.57%
  3. Geode Capital Management LLC — 1.03%
  4. State Street Corp — 0.73%
  5. Jane Street Group LLC — 0.36%
  6. Goldman Sachs Group Inc. — 0.33%
Learn More about top institutional investors of Protalix BioTherapeutics stock.

Which institutional investors are selling Protalix BioTherapeutics stock?

In the previous quarter, PLX stock was sold by these institutional investors:
  1. Opaleye Management Inc.
  2. Renaissance Technologies LLC
  3. XTX Topco Ltd
  4. Simplex Trading LLC
  5. New York State Common Retirement Fund
  6. The Manufacturers Life Insurance Company
  7. Group One Trading LLC

Which institutional investors are buying Protalix BioTherapeutics stock?

During the previous quarter, PLX stock was purchased by institutional investors including:
  1. Jane Street Group LLC
  2. Round Rock Advisors LLC
  3. Goldman Sachs Group Inc.
  4. State Street Corp
  5. Main Street Financial Solutions LLC
  6. Lazard Asset Management LLC
  7. HRT Financial LP
  8. Wells Fargo & Company MN
In the previous year, these company insiders have bought Protalix BioTherapeutics stock:
  1. Aharon Schwartz (Director)
  2. Dror Bashan (CEO)
Learn More investors buying Protalix BioTherapeutics stock.