| 11/17/2025 | Millennium Management LLC | 104,772 | $0.21M | 0.0% | -19.6% | 0.852% |  |
| 11/14/2025 | Two Sigma Investments LP | 31,506 | $62K | 0.0% | N/A | 0.258% |  |
| 11/10/2025 | Monaco Asset Management SAM | 311,137 | $0.62M | 0.0% | -47.4% | 2.551% |  |
| 8/14/2025 | Jane Street Group LLC | 46,635 | $69K | 0.0% | N/A | 0.382% |  |
| 8/13/2025 | Marshall Wace LLP | 16,928 | $25K | 0.0% | N/A | 0.139% |  |
| 8/8/2025 | Geode Capital Management LLC | 61,599 | $92K | 0.0% | -55.2% | 0.505% |  |
| 8/7/2025 | Monaco Asset Management SAM | 591,937 | $0.88M | 0.2% | +17.1% | 4.852% |  |
| 6/27/2025 | Goldman Sachs Group Inc. | 44,373 | $73K | 0.0% | +140.9% | 0.364% |  |
| 5/21/2025 | Acadian Asset Management LLC | 31,138 | $50K | 0.0% | N/A | 0.255% |  |
| 5/16/2025 | Goldman Sachs Group Inc. | 44,373 | $73K | 0.0% | +140.9% | 0.364% |  |
| 5/16/2025 | AQR Capital Management LLC | 41,302 | $68K | 0.0% | N/A | 0.339% |  |
| 5/12/2025 | Nuveen LLC | 55,886 | $92K | 0.0% | N/A | 0.458% |  |
| 5/8/2025 | Monaco Asset Management SAM | 505,451 | $0.83M | 0.2% | -12.1% | 4.144% |  |
| 2/19/2025 | Public Employees Retirement System of Ohio | 7,540 | $26K | 0.0% | N/A | 0.062% |  |
| 2/17/2025 | Squarepoint Ops LLC | 19,009 | $65K | 0.0% | N/A | 0.156% |  |
| 2/17/2025 | Two Sigma Investments LP | 53,175 | $0.18M | 0.0% | N/A | 0.437% |  |
| 2/17/2025 | Trustees of Columbia University in the City of New York | 133,903 | $0.46M | 0.1% | N/A | 1.099% |  |
| 2/17/2025 | Sanofi | 244,083 | $0.84M | 0.5% | N/A | 2.004% |  |
| 2/17/2025 | Millennium Management LLC | 10,725 | $37K | 0.0% | -89.3% | 0.088% |  |
| 2/17/2025 | Jacobs Levy Equity Management Inc. | 34,844 | $0.12M | 0.0% | N/A | 0.286% |  |
| 2/17/2025 | Deutsche Bank AG | 25,018 | $86K | 0.0% | +699.8% | 0.205% |  |
| 2/17/2025 | Cubist Systematic Strategies LLC | 12,249 | $42K | 0.0% | N/A | 0.101% |  |
| 2/17/2025 | Ameriprise Financial Inc. | 15,548 | $53K | 0.0% | N/A | 0.128% |  |
| 2/17/2025 | ArrowMark Colorado Holdings LLC | 81,482 | $0.28M | 0.0% | N/A | 0.669% |  |
| 2/17/2025 | Acorn Capital Advisors LLC | 803,425 | $2.76M | 1.5% | N/A | 6.596% |  |
| 2/13/2025 | Mariner LLC | 121,427 | $0.42M | 0.0% | N/A | 0.997% |  |
| 2/13/2025 | Townsquare Capital LLC | 17,466 | $60K | 0.0% | N/A | 0.143% |  |
| 2/13/2025 | Raymond James Financial Inc. | 10,746 | $37K | 0.0% | N/A | 0.088% |  |
| 2/11/2025 | AXQ Capital LP | 10,581 | $36K | 0.0% | N/A | 0.087% |  |
| 2/10/2025 | Monaco Asset Management SAM | 574,816 | $1.98M | 0.3% | N/A | 4.719% |  |
| 2/6/2025 | Raymond James Financial Inc. | 10,746 | $37K | 0.0% | N/A | 0.088% |  |
| 2/3/2025 | Hussman Strategic Advisors Inc. | 10,500 | $36K | 0.0% | N/A | 0.086% |  |
| 1/30/2025 | Rhumbline Advisers | 105,544 | $0.36M | 0.0% | +1,164.3% | 0.867% |  |
| 1/29/2025 | Savant Capital LLC | 15,281 | $53K | 0.0% | N/A | 0.125% |  |
| 1/27/2025 | Bleakley Financial Group LLC | 43,360 | $0.15M | 0.0% | N/A | 0.356% |  |
| 1/22/2025 | Drive Wealth Management LLC | 10,928 | $38K | 0.0% | N/A | 0.090% |  |
| 11/27/2024 | Franklin Resources Inc. | 4,857 | $0.23M | 0.0% | N/A | 0.040% |  |
| 11/19/2024 | Barclays PLC | 10,443 | $0.47M | 0.0% | +105.2% | 0.086% |  |
| 11/16/2024 | Geode Capital Management LLC | 131,768 | $5.88M | 0.0% | +22.4% | 1.082% |  |
| 11/15/2024 | Barclays PLC | 10,443 | $0.47M | 0.0% | +105.2% | 0.086% |  |
| 11/15/2024 | Jane Street Group LLC | 16,437 | $0.73M | 0.0% | N/A | 0.135% |  |
| 11/15/2024 | State Street Corp | 110,164 | $4.92M | 0.0% | +35.5% | 0.904% |  |
| 11/15/2024 | Point72 Asset Management L.P. | 76,685 | $3.42M | 0.0% | N/A | 0.630% |  |
| 11/14/2024 | Eventide Asset Management LLC | 190,000 | $8.48M | 0.1% | N/A | 1.560% |  |
| 11/14/2024 | MetLife Investment Management LLC | 3,563 | $0.16M | 0.0% | N/A | 0.029% |  |
| 11/13/2024 | BNP Paribas Financial Markets | 1,298 | $58K | 0.0% | +199.1% | 0.011% |  |
| 11/13/2024 | FMR LLC | 426,302 | $19.02M | 0.0% | +137.3% | 3.500% |  |
| 10/23/2024 | Values First Advisors Inc. | 741 | $33K | 0.0% | N/A | 0.006% |  |
| 8/13/2024 | Ensign Peak Advisors Inc | 64,481 | $1.16M | 0.0% | +150.6% | 0.540% |  |
| 8/9/2024 | Renaissance Technologies LLC | 14,764 | $0.27M | 0.0% | N/A | 0.124% |  |
| 8/9/2024 | Harvard Management Co. Inc. | 162,965 | $2.93M | 0.2% | N/A | 1.365% |  |
| 8/1/2024 | Rhumbline Advisers | 7,658 | $0.14M | 0.0% | +11,681.5% | 0.064% |  |
| 7/26/2024 | Bank of New York Mellon Corp | 17,569 | $0.32M | 0.0% | N/A | 0.147% |  |
| 5/17/2024 | Ikarian Capital LLC | 22,335 | $0.38M | 0.0% | N/A | 0.685% |  |
| 5/15/2024 | ARCH Venture Management LLC | 320,482 | $5.46M | 6.5% | N/A | 9.831% |  |
| 5/15/2024 | Affinity Asset Advisors LLC | 27,777 | $0.47M | 0.1% | N/A | 0.852% |  |
| 5/14/2024 | Platinum Investment Management Ltd. | 109,964 | $1.87M | 0.1% | N/A | 3.373% |  |
| 5/10/2024 | Acadian Asset Management LLC | 3,695 | $62K | 0.0% | N/A | 0.113% |  |
| 5/10/2024 | Vanguard Group Inc. | 107,752 | $1.84M | 0.0% | N/A | 3.305% |  |
| 5/6/2024 | Atlas Venture Life Science Advisors LLC | 2,092,106 | $35.65M | 3.3% | N/A | 64.254% |  |
| 5/3/2024 | Carlyle Group Inc. | 1,102,741 | $18.07M | 1.1% | N/A | 33.826% |  |
| 4/23/2024 | BML Capital Management LLC | 24,894 | $0.42M | 0.3% | N/A | 0.764% |  |
| 4/22/2024 | Vivo Capital LLC | 370,068 | $6.31M | 0.5% | N/A | 11.366% |  |