| 11/21/2025 | CIBC Bancorp USA Inc. | 14,116 | $74K | 0.0% | N/A | 0.008% |  |
| 11/20/2025 | Mayport LLC | 49,681 | $0.26M | 0.1% | N/A | 0.029% |  |
| 11/17/2025 | Abel Hall LLC | 11,175 | $58K | 0.0% | N/A | 0.006% |  |
| 11/17/2025 | TCG Crossover Management LLC | 1,810,351 | $9.45M | 0.5% | N/A | 1.045% |  |
| 11/17/2025 | Susquehanna Fundamental Investments LLC | 120,272 | $0.63M | 0.0% | -56.9% | 0.069% |  |
| 11/17/2025 | Polymer Capital Management US LLC | 21,693 | $0.11M | 0.0% | -38.0% | 0.013% |  |
| 11/17/2025 | Prelude Capital Management LLC | 19,700 | $0.10M | 0.0% | +18.7% | 0.011% |  |
| 11/17/2025 | Mercer Global Advisors Inc. ADV | 13,055 | $68K | 0.0% | N/A | 0.008% |  |
| 11/17/2025 | Millennium Management LLC | 744,044 | $3.88M | 0.0% | -60.2% | 0.429% |  |
| 11/17/2025 | MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 70,029 | $0.37M | 0.0% | -15.0% | 0.040% |  |
| 11/17/2025 | HighVista Strategies LLC | 240,459 | $1.26M | 0.3% | +60.6% | 0.139% |  |
| 11/17/2025 | Brevan Howard Capital Management LP | 61,629 | $0.32M | 0.0% | N/A | 0.036% |  |
| 11/17/2025 | Casdin Capital LLC | 11,341,381 | $59.20M | 4.9% | -0.5% | 6.544% |  |
| 11/17/2025 | Commodore Capital LP | 17,000,000 | $88.74M | 4.3% | +27.3% | 9.808% |  |
| 11/17/2025 | Bank of America Corp DE | 1,195,843 | $6.24M | 0.0% | -9.4% | 0.690% |  |
| 11/17/2025 | Boothbay Fund Management LLC | 137,841 | $0.72M | 0.0% | -38.2% | 0.080% |  |
| 11/17/2025 | Algert Global LLC | 408,840 | $2.13M | 0.0% | -59.2% | 0.236% |  |
| 11/14/2025 | Creative Planning | 79,873 | $0.42M | 0.0% | +10.0% | 0.046% |  |
| 11/14/2025 | Raymond James Financial Inc. | 214,823 | $1.12M | 0.0% | +12.8% | 0.124% |  |
| 11/14/2025 | Bellevue Group AG | 8,345,610 | $43.56M | 0.9% | +1.4% | 4.815% |  |
| 11/14/2025 | Man Group plc | 187,821 | $0.98M | 0.0% | -37.1% | 0.108% |  |
| 11/14/2025 | California State Teachers Retirement System | 138,551 | $0.72M | 0.0% | +30.4% | 0.080% |  |
| 11/14/2025 | Zurcher Kantonalbank Zurich Cantonalbank | 47,621 | $0.25M | 0.0% | +65.9% | 0.027% |  |
| 11/14/2025 | Brooklyn Investment Group | 27,818 | $0.15M | 0.0% | -72.5% | 0.016% |  |
| 11/14/2025 | UBS AM A Distinct Business Unit of UBS Asset Management Americas LLC | 202,244 | $1.06M | 0.0% | -50.5% | 0.117% |  |
| 11/14/2025 | Two Sigma Investments LP | 1,095,635 | $5.72M | 0.0% | +7.1% | 0.632% |  |
| 11/14/2025 | Quinn Opportunity Partners LLC | 30,000 | $0.16M | 0.0% | +200.0% | 0.017% |  |
| 11/13/2025 | UBS Group AG | 152,253 | $0.80M | 0.0% | -12.0% | 0.088% |  |
| 11/13/2025 | BNP Paribas Financial Markets | 32,242 | $0.17M | 0.0% | -9.0% | 0.019% |  |
| 11/13/2025 | Franklin Resources Inc. | 379,363 | $1.98M | 0.0% | -3.7% | 0.219% |  |
| 11/13/2025 | Russell Investments Group Ltd. | 12,439 | $65K | 0.0% | -38.1% | 0.007% |  |
| 11/13/2025 | Dynamic Technology Lab Private Ltd | 54,153 | $0.28M | 0.0% | +219.8% | 0.031% |  |
| 11/12/2025 | Intellectus Partners LLC | 56,425 | $0.30M | 0.1% | -8.1% | 0.033% |  |
| 11/12/2025 | Barclays PLC | 461,879 | $2.41M | 0.0% | -17.0% | 0.266% |  |
| 11/12/2025 | Dimensional Fund Advisors LP | 2,482,950 | $12.96M | 0.0% | -11.0% | 1.433% |  |
| 11/12/2025 | Cresset Asset Management LLC | 38,932 | $0.20M | 0.0% | +5.0% | 0.022% |  |
| 11/12/2025 | 49 Wealth Management LLC | 13,101 | $68K | 0.0% | N/A | 0.008% |  |
| 11/12/2025 | Rafferty Asset Management LLC | 151,575 | $0.79M | 0.0% | -16.7% | 0.087% |  |
| 11/12/2025 | Private Capital Advisors Inc. | 53,648 | $0.28M | 0.0% | -87.9% | 0.031% |  |
| 11/12/2025 | Intech Investment Management LLC | 38,709 | $0.20M | 0.0% | -28.6% | 0.022% |  |
| 11/10/2025 | TD Asset Management Inc | 118,256 | $0.62M | 0.0% | +19.4% | 0.068% |  |
| 11/10/2025 | Raiffeisen Bank International AG | 220,000 | $1.14M | 0.0% | +22.2% | 0.127% |  |
| 11/10/2025 | China Universal Asset Management Co. Ltd. | 30,221 | $0.16M | 0.0% | -12.2% | 0.017% |  |
| 11/7/2025 | NEOS Investment Management LLC | 93,465 | $0.49M | 0.0% | -3.8% | 0.054% |  |
| 11/7/2025 | GSA Capital Partners LLP | 129,422 | $0.68M | 0.1% | +60.6% | 0.075% |  |
| 11/7/2025 | Vanguard Group Inc. | 9,395,744 | $49.05M | 0.0% | +0.2% | 5.450% |  |
| 11/7/2025 | JPMorgan Chase & Co. | 462,379 | $2.41M | 0.0% | -89.3% | 0.268% |  |
| 11/6/2025 | Rhumbline Advisers | 217,592 | $1.14M | 0.0% | -1.9% | 0.126% |  |
| 11/6/2025 | Profund Advisors LLC | 33,700 | $0.18M | 0.0% | -12.7% | 0.020% |  |
| 11/6/2025 | ProShare Advisors LLC | 28,776 | $0.15M | 0.0% | -14.2% | 0.017% |  |
| 11/5/2025 | Alps Advisors Inc. | 82,425 | $0.43M | 0.0% | -10.9% | 0.048% |  |
| 11/5/2025 | Savant Capital LLC | 120,374 | $0.63M | 0.0% | -28.5% | 0.070% |  |
| 11/4/2025 | Thrivent Financial for Lutherans | 87,418 | $0.46M | 0.0% | -47.5% | 0.051% |  |
| 11/3/2025 | Federated Hermes Inc. | 36,000 | $0.19M | 0.0% | -49.5% | 0.021% |  |
| 10/31/2025 | Vanguard Personalized Indexing Management LLC | 27,871 | $0.15M | 0.0% | +8.1% | 0.016% |  |
| 10/29/2025 | Wealth Enhancement Advisory Services LLC | 47,147 | $0.25M | 0.0% | +15.0% | 0.027% |  |
| 10/23/2025 | SG Americas Securities LLC | 31,945 | $0.17M | 0.0% | +17.8% | 0.019% |  |
| 10/15/2025 | CWM LLC | 67,928 | $0.36M | 0.0% | +19.2% | 0.039% |  |
| 10/10/2025 | Congress Asset Management Co. | 408,842 | $2.13M | 0.0% | +160.9% | 0.237% |  |
| 10/9/2025 | Voya Investment Management LLC | 24,575 | $0.13M | 0.0% | -32.4% | 0.014% |  |
| 8/15/2025 | Captrust Financial Advisors | 14,111 | $49K | 0.0% | N/A | 0.008% |  |
| 8/15/2025 | Rafferty Asset Management LLC | 181,957 | $0.63M | 0.0% | -11.3% | 0.106% |  |
| 8/15/2025 | Man Group plc | 298,510 | $1.03M | 0.0% | +45.1% | 0.173% |  |
| 8/15/2025 | Engineers Gate Manager LP | 38,719 | $0.13M | 0.0% | +31.5% | 0.022% |  |
| 8/15/2025 | BNP Paribas Financial Markets | 35,441 | $0.12M | 0.0% | +90.6% | 0.021% |  |
| 8/15/2025 | Boothbay Fund Management LLC | 222,987 | $0.77M | 0.0% | -1.7% | 0.129% |  |
| 8/15/2025 | Bellevue Group AG | 8,230,870 | $28.48M | 0.6% | +11.6% | 4.774% |  |
| 8/15/2025 | Bank of America Corp DE | 1,320,130 | $4.57M | 0.0% | +138.1% | 0.766% |  |
| 8/15/2025 | Ameriprise Financial Inc. | 410,896 | $1.42M | 0.0% | +10.4% | 0.238% |  |
| 8/15/2025 | AQR Capital Management LLC | 1,083,465 | $3.75M | 0.0% | +196.9% | 0.628% |  |
| 8/14/2025 | MPM Bioimpact LLC | 2,282,680 | $7.90M | 1.4% | -0.6% | 1.324% |  |
| 8/14/2025 | Commodore Capital LP | 13,350,000 | $46.19M | 3.3% | N/A | 7.743% |  |
| 8/14/2025 | Raymond James Financial Inc. | 190,488 | $0.66M | 0.0% | +3.2% | 0.110% |  |
| 8/14/2025 | TFG Asset Management GP Ltd | 699,000 | $2.42M | 0.4% | +12.9% | 0.405% |  |
| 8/14/2025 | The Manufacturers Life Insurance Company | 212,126 | $0.73M | 0.0% | +3.2% | 0.123% |  |
| 8/14/2025 | Sei Investments Co. | 25,630 | $89K | 0.0% | N/A | 0.015% |  |
| 8/14/2025 | OCONNOR A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS LLC | 127,036 | $0.44M | 0.0% | -66.8% | 0.074% |  |
| 8/14/2025 | HighVista Strategies LLC | 149,701 | $0.52M | 0.2% | N/A | 0.087% |  |
| 8/14/2025 | Diadema Partners LP | 43,616 | $0.15M | 0.0% | -92.2% | 0.025% |  |
| 8/14/2025 | Cerity Partners LLC | 14,833 | $51K | 0.0% | N/A | 0.009% |  |
| 8/14/2025 | Federated Hermes Inc. | 71,217 | $0.25M | 0.0% | -26.1% | 0.041% |  |
| 8/13/2025 | Jump Financial LLC | 15,301 | $53K | 0.0% | N/A | 0.009% |  |
| 8/13/2025 | Cresset Asset Management LLC | 37,084 | $0.13M | 0.0% | +26.2% | 0.022% |  |
| 8/13/2025 | Tema Etfs LLC | 97,150 | $0.34M | 0.1% | +9.0% | 0.056% |  |
| 8/13/2025 | Marshall Wace LLP | 51,698 | $0.18M | 0.0% | N/A | 0.030% |  |
| 8/13/2025 | Invesco Ltd. | 273,383 | $0.95M | 0.0% | +47.9% | 0.159% |  |
| 8/13/2025 | Virtus Investment Advisers LLC | 27,256 | $94K | 0.0% | -20.6% | 0.016% |  |
| 8/13/2025 | Norges Bank | 835,874 | $2.89M | 0.0% | N/A | 0.485% |  |
| 8/13/2025 | Quadrature Capital Ltd | 13,496 | $47K | 0.0% | N/A | 0.008% |  |
| 8/13/2025 | Hsbc Holdings PLC | 104,257 | $0.35M | 0.0% | -10.4% | 0.060% |  |
| 8/13/2025 | Quadrant Capital Group LLC | 11,791 | $41K | 0.0% | +245.1% | 0.007% |  |
| 8/13/2025 | Russell Investments Group Ltd. | 20,109 | $70K | 0.0% | -49.1% | 0.012% |  |
| 8/12/2025 | XTX Topco Ltd | 241,230 | $0.84M | 0.0% | +201.9% | 0.140% |  |
| 8/12/2025 | Prudential Financial Inc. | 358,225 | $1.24M | 0.0% | -8.9% | 0.208% |  |
| 8/12/2025 | American Century Companies Inc. | 349,420 | $1.21M | 0.0% | +13.2% | 0.203% |  |
| 8/12/2025 | Rhumbline Advisers | 221,853 | $0.77M | 0.0% | +27.4% | 0.129% |  |
| 8/12/2025 | Franklin Resources Inc. | 394,122 | $1.36M | 0.0% | +130.4% | 0.229% |  |
| 8/12/2025 | Legal & General Group Plc | 112,316 | $0.39M | 0.0% | -13.1% | 0.065% |  |
| 8/12/2025 | JPMorgan Chase & Co. | 4,338,403 | $15.01M | 0.0% | -11.6% | 2.516% |  |
| 8/12/2025 | Dynamic Technology Lab Private Ltd | 16,935 | $59K | 0.0% | -15.6% | 0.010% |  |