RPTX Insider Trading

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Insider Ownership Percentage: 11.50%

Insider Buying (Last 12 Months): $0.00

Insider Selling (Last 12 Months): $0.00

Repare Therapeutics Insider Trading History Chart

Repare Therapeutics Share Price & Price History

^$2.23

▲ +0.06 (2.76%)

As of 12/4/2025 05:00 PM ET

Days: 30 | 90 | 365

Repare Therapeutics Insider Trading History

Transaction Date	Insider Name	Title	Buy/Sell	Number of Shares	Average Share Price	Total Transaction	Shares Held After Transaction
4/1/2024	Lloyd Mitchell Segal	CEO	Sell	2,491	$4.63	$11,533.33	107,558
4/1/2024	Michael Zinda	EVP	Sell	410	$4.66	$1,910.60	71,908
4/1/2024	Steve Forte	CFO	Sell	789	$4.61	$3,637.29	44,775
3/27/2024	Lloyd Mitchell Segal	CEO	Sell	2,650	$4.63	$12,269.50	83,866
3/27/2024	Michael Zinda	EVP	Sell	450	$4.62	$2,079.00	72,768
3/27/2024	Steve Forte	CFO	Sell	825	$4.62	$3,811.50	42,212
3/25/2024	Lloyd Mitchell Segal	CEO	Sell	2,650	$4.79	$12,693.50	89,166
3/25/2024	Michael Zinda	EVP	Sell	450	$4.78	$2,151.00	73,668
3/25/2024	Steve Forte	CFO	Sell	825	$4.79	$3,951.75	43,862
11/15/2023	Bvf Partners L P/Il	Major Shareholder	Buy	931,556	$5.00	$4,657,780.00	5,155,739
11/2/2023	Bvf Partners L P/Il	Major Shareholder	Buy	783,709	$3.60	$2,821,352.40	4,662,402
6/6/2023	Michael Zinda	EVP	Sell	1,200	$12.04	$14,448.00	69,391
12/9/2022	Davis Jerel	Director	Sell	250,000	$16.00	$4,000,000.00	2,094,451

SEC Filings (Institutional Ownership Changes) for Repare Therapeutics (NASDAQ:RPTX)

85.09% of Repare Therapeutics stock is owned by institutions. Institutional ownership can be a sign of analyst confidence in the fundamentals of the stock.

Institutional Buying and Selling by Quarter

Repare Therapeutics Institutional Trading History

Reporting Date	Hedge Fund	Shares Held	Market Value	% of Portfolio	Quarterly Change in Shares	Ownership in Company
11/26/2025	Lantern Wealth Advisors LLC	20,000	$35K	0.0%	N/A	0.047%
11/17/2025	Citadel Advisors LLC	699,297	$1.23M	0.0%	-26.6%	1.628%
11/14/2025	Squarepoint Ops LLC	65,243	$0.12M	0.0%	N/A	0.152%
8/15/2025	Rangeley Capital LLC	355,292	$0.49M	0.6%	N/A	0.827%
8/15/2025	Militia Capital Partners LP	119,176	$0.17M	0.1%	N/A	0.277%
8/14/2025	Redmile Group LLC	1,586,174	$2.21M	0.2%	-15.8%	3.692%
8/12/2025	XTX Topco Ltd	43,174	$60K	0.0%	N/A	0.101%
8/8/2025	Quinn Opportunity Partners LLC	40,000	$56K	0.0%	N/A	0.093%
5/21/2025	Acadian Asset Management LLC	640,332	$0.62M	0.0%	+35.6%	1.493%
5/15/2025	Redmile Group LLC	1,884,389	$1.86M	0.2%	-1.7%	4.393%
5/15/2025	MPM Bioimpact LLC	819,924	$0.81M	0.1%	-33.4%	1.912%
5/15/2025	MPM Asset Management LLC	1,121,318	$1.11M	1.6%	-33.4%	2.614%
5/14/2025	Affinity Asset Advisors LLC	200,000	$0.20M	0.0%	+100.0%	0.466%
5/7/2025	ARK Investment Management LLC	1,124,483	$1.11M	0.0%	-43.8%	2.622%
2/17/2025	Redmile Group LLC	1,916,089	$2.51M	0.2%	-1.4%	4.507%
2/17/2025	MPM Asset Management LLC	1,683,707	$2.21M	1.8%	-24.9%	3.961%
2/17/2025	MPM Bioimpact LLC	1,231,154	$1.61M	0.2%	-24.9%	2.896%
2/17/2025	Millennium Management LLC	170,959	$0.22M	0.0%	+65.5%	0.402%
2/14/2025	Lynx1 Capital Management LP	79,176	$0.10M	0.0%	N/A	0.186%
2/14/2025	Blue Owl Capital Holdings LP	3,443,659	$4.51M	1.1%	+2.1%	8.101%
2/14/2025	Stifel Financial Corp	89,500	$0.12M	0.0%	+73.1%	0.211%
2/14/2025	Tower Research Capital LLC TRC	34,423	$45K	0.0%	+204.7%	0.081%
2/13/2025	Marshall Wace LLP	46,876	$61K	0.0%	-60.6%	0.110%
2/13/2025	Affinity Asset Advisors LLC	100,000	$0.13M	0.0%	-42.3%	0.235%
2/13/2025	Renaissance Technologies LLC	347,460	$0.46M	0.0%	-23.4%	0.817%
2/12/2025	JPMorgan Chase & Co.	85,802	$0.11M	0.0%	+2,144,950.0%	0.202%
2/10/2025	Nikko Asset Management Americas Inc.	116,249	$0.15M	0.0%	-53.4%	0.273%
2/4/2025	ARK Investment Management LLC	1,999,997	$2.62M	0.0%	-20.3%	4.705%
1/30/2025	Vontobel Holding Ltd.	35,000	$46K	0.0%	+45.8%	0.082%
1/28/2025	Sumitomo Mitsui Trust Group Inc.	116,249	$0.15M	0.0%	-53.4%	0.273%
11/19/2024	Barclays PLC	8,330	$29K	0.0%	+1,471.7%	0.020%
11/15/2024	Barclays PLC	8,330	$29K	0.0%	+1,471.7%	0.020%
11/15/2024	Stifel Financial Corp	51,700	$0.18M	0.0%	+36.4%	0.122%
11/5/2024	Sumitomo Mitsui Trust Group Inc.	249,215	$0.86M	0.0%	-10.1%	0.587%
11/5/2024	GSA Capital Partners LLP	240,522	$0.83M	0.1%	-19.7%	0.567%
10/31/2024	ARK Investment Management LLC	2,509,737	$8.63M	0.1%	-4.6%	5.913%
10/16/2024	Vontobel Holding Ltd.	24,000	$83K	0.0%	+20.0%	0.057%
10/10/2024	Exchange Traded Concepts LLC	50,441	$0.17M	0.0%	+21.2%	0.119%
8/15/2024	Blue Owl Capital Holdings LP	3,372,499	$11.13M	3.1%	+8.0%	7.945%
8/14/2024	Squarepoint Ops LLC	142,974	$0.47M	0.0%	+428.4%	0.337%
8/14/2024	Marshall Wace LLP	82,590	$0.27M	0.0%	N/A	0.195%
8/14/2024	Bank of Montreal Can	110,935	$0.37M	0.0%	+5.4%	0.261%
8/12/2024	XTX Topco Ltd	33,320	$0.11M	0.0%	N/A	0.079%
8/9/2024	Renaissance Technologies LLC	458,700	$1.51M	0.0%	+30.7%	1.081%
8/9/2024	Dimensional Fund Advisors LP	13,265	$44K	0.0%	-67.5%	0.031%
8/6/2024	Acadian Asset Management LLC	417,929	$1.37M	0.0%	+212.1%	0.985%
7/26/2024	ARK Investment Management LLC	2,630,364	$8.68M	0.1%	-2.7%	6.198%
7/19/2024	Sumitomo Mitsui Trust Holdings Inc.	277,168	$0.92M	0.0%	-10.1%	0.653%
5/29/2024	Opaleye Management Inc.	67,561	$0.32M	0.1%	N/A	0.159%
5/16/2024	Redmile Group LLC	2,016,302	$9.50M	0.3%	-6.2%	4.751%
5/10/2024	Acadian Asset Management LLC	133,893	$0.63M	0.0%	+53.5%	0.315%
5/3/2024	GSA Capital Partners LLP	126,208	$0.59M	0.0%	-12.6%	0.297%
5/3/2024	Nikko Asset Management Americas Inc.	308,449	$1.43M	0.0%	-5.4%	0.727%
4/19/2024	Sumitomo Mitsui Trust Holdings Inc.	308,449	$1.45M	0.0%	-5.4%	0.834%
2/15/2024	BVF Inc. IL	10,333,600	$75.44M	1.9%	+24.6%	24.528%
2/7/2024	Jump Financial LLC	39,603	$0.29M	0.0%	N/A	0.094%
2/6/2024	SRS Capital Advisors Inc.	10,000	$73K	0.0%	+100.0%	0.024%
1/30/2024	Vontobel Holding Ltd.	15,000	$0.11M	0.0%	N/A	0.036%
1/17/2024	ARK Investment Management LLC	2,821,560	$20.60M	0.1%	+7.7%	6.697%
1/8/2024	Harbor Capital Advisors Inc.	48,055	$0.35M	0.1%	+14.2%	0.114%
1/5/2024	Exchange Traded Concepts LLC	13,585	$99K	0.0%	+34.0%	0.032%
11/15/2023	Redmile Group LLC	2,404,695	$29.05M	1.4%	-1.0%	5.708%
11/14/2023	Blackstone Inc.	25,957	$0.31M	0.0%	+14.9%	0.062%
11/14/2023	Trexquant Investment LP	29,456	$0.36M	0.0%	-47.3%	0.070%
11/13/2023	Connor Clark & Lunn Investment Management Ltd.	14,919	$0.18M	0.0%	+30.6%	0.035%
11/13/2023	FMR LLC	1,079,847	$13.05M	0.0%	-7.6%	2.563%
10/30/2023	Sumitomo Mitsui Trust Holdings Inc.	326,011	$3.94M	0.0%	+1.1%	0.775%
10/24/2023	Raymond James Financial Services Advisors Inc.	12,357	$0.15M	0.0%	N/A	0.029%
10/20/2023	Harbor Capital Advisors Inc.	42,085	$0.51M	0.1%	+13.8%	0.100%
10/18/2023	ARK Investment Management LLC	2,620,883	$31.66M	0.2%	-0.3%	6.227%
9/21/2023	Barclays PLC	3,409	$36K	0.0%	N/A	0.008%
8/11/2023	Hershey Trust Co.	5,883	$62K	0.0%	N/A	0.014%
8/11/2023	Trexquant Investment LP	55,932	$0.59M	0.0%	-36.5%	0.133%
8/9/2023	Versant Venture Management LLC	2,646,657	$28M	33.2%	N/A	6.288%
8/8/2023	Candriam S.C.A.	50,001	$0.53M	0.0%	N/A	0.119%
8/7/2023	Acadian Asset Management LLC	81,629	$0.86M	0.0%	-3.1%	0.194%
8/2/2023	Bank of Montreal Can	117,824	$1.47M	0.0%	N/A	0.280%
7/31/2023	Sumitomo Mitsui Trust Holdings Inc.	322,616	$3.41M	0.0%	+99.6%	0.766%
7/25/2023	DekaBank Deutsche Girozentrale	40,000	$0.43M	0.0%	+174.0%	0.095%
7/20/2023	Exchange Traded Concepts LLC	11,445	$0.12M	0.0%	N/A	0.027%
7/11/2023	Harbor Capital Advisors Inc.	36,984	$0.39M	0.1%	+10.0%	0.088%
7/10/2023	ARK Investment Management LLC	2,628,073	$27.81M	0.2%	-4.0%	6.244%
5/15/2023	Sio Capital Management LLC	228,538	$2.25M	1.1%	N/A	0.543%
5/11/2023	Acadian Asset Management LLC	84,273	$0.83M	0.0%	+222.1%	0.200%
5/11/2023	CHI Advisors LLC	2,997,939	$29.50M	7.8%	+7.1%	7.124%
5/9/2023	Tower Research Capital LLC TRC	11,316	$0.11M	0.0%	+533.2%	0.027%
5/3/2023	Nikko Asset Management Americas Inc.	161,598	$1.47M	0.0%	-7.1%	0.384%
5/1/2023	Compagnie Lombard Odier SCmA	14,000	$0.14M	0.0%	N/A	0.033%
4/27/2023	Sumitomo Mitsui Trust Holdings Inc.	161,598	$1.59M	0.0%	-7.1%	0.384%
4/17/2023	ARK Investment Management LLC	2,737,324	$26.94M	0.2%	+12.7%	6.505%
2/13/2023	Nikko Asset Management Americas Inc.	174,033	$2.55M	0.0%	-7.0%	0.415%
2/10/2023	HRT Financial LP	22,529	$0.33M	0.0%	N/A	0.054%
2/8/2023	Swiss National Bank	45,500	$0.67M	0.0%	+2.7%	0.108%
2/7/2023	TD Asset Management Inc	22,758	$0.34M	0.0%	-22.2%	0.054%
2/1/2023	Bank of Montreal Can	128,827	$1.92M	0.0%	-3.8%	0.307%
1/30/2023	Sumitomo Mitsui Trust Holdings Inc.	174,033	$2.56M	0.0%	-7.0%	0.415%
1/26/2023	Dupont Capital Management Corp	12,271	$0.18M	0.0%	N/A	0.029%
1/24/2023	ARK Investment Management LLC	2,428,055	$35.72M	0.3%	-7.7%	5.786%
1/20/2023	Harbor Capital Advisors Inc.	34,572	$0.51M	0.5%	N/A	0.082%
11/15/2022	Ensign Peak Advisors Inc	90,803	$1.10M	0.0%	+6.4%	0.216%

Data available starting January 2016

Repare Therapeutics Inc., a clinical-stage precision oncology company, engages in the discovery and development of therapeutics by using its synthetic lethality approach in Canada and the United States. It uses its SNIPRx, a proprietary, genome-wide, and CRISPR-enabled platform, to discover, validate, and build a pipeline of SL-based therapeutics that focuses on genomic instability, including DNA damage repair. The company's lead product candidate is Camonsertib (RP-3500), an oral small molecule inhibitor under Phase ½ development for the treatment of solid tumors with specific DNA damage repair-related genomic alterations. It is also developing Lunresertib (RP-6306), a PKMYT1 Inhibitor, which is under Phase 1 clinical trial for tumors with genetic alterations characterized by CCNE1 amplification; RP-1664, an oral PLK4 inhibitor, under Phase 1 clinical trial designed to harness the synthetic lethal relationship with TRIM37 amplification or overexpression in solid tumors; and RP-3467, a polymerase theta adenosinetriphosphatase (ATPase) inhibitor, a SL target associated with BRCA mutations and other genomic alterations. The company has license and collaboration agreement with Hoffmann-La Roche Inc. and F. Hoffmann-La Roche Ltd; Bristol-Myers Squibb Company; New York University; and Ono Pharmaceutical Co., as well as a clinical study and collaboration agreement with Debiopharm to explore the synthetic lethal combination of PKMYT1 and WEE1 inhibition in cancer. Repare Therapeutics Inc. was incorporated in 2016 and is headquartered in Montréal, Canada.

Today's Range

Now: $2.23

$2.14

$2.24

50 Day Range

MA: $1.90

$1.65

$2.23

52 Week Range

Now: $2.23

$0.89

$4.07

Volume

382,297 shs

Average Volume

1,168,470 shs

Market Capitalization

$95.87 million

P/E Ratio

N/A

Dividend Yield

N/A

Beta

1.02

Who are the company insiders with the largest holdings of Repare Therapeutics?: Repare Therapeutics' top insider investors include:
Lloyd Mitchell Segal (CEO)
Michael Zinda (EVP)
Steve Forte (CFO)
Learn More about top insider investors at Repare Therapeutics.
Who are the major institutional investors of Repare Therapeutics?: Repare Therapeutics' top institutional investors include:
Citadel Advisors LLC — 1.63%
Squarepoint Ops LLC — 0.15%
Lantern Wealth Advisors LLC — 0.05%
Learn More about top institutional investors of Repare Therapeutics stock.
Which institutional investors are selling Repare Therapeutics stock?: During the previous quarter, RPTX stock was sold by these institutional investors:
Citadel Advisors LLC
Which institutional investors are buying Repare Therapeutics stock?: During the last quarter, RPTX stock was purchased by institutional investors including:
Squarepoint Ops LLC
Lantern Wealth Advisors LLC