| 2/19/2026 | T. Rowe Price Investment Management Inc. | 1,354,761 | $4.95M | 0.0% | N/A | 2.141% |  |
| 2/19/2026 | Invesco Ltd. | 28,231 | $0.10M | 0.0% | N/A | 0.045% |  |
| 2/18/2026 | EP Wealth Advisors LLC | 41,167 | $0.15M | 0.0% | N/A | 0.065% |  |
| 2/18/2026 | Sphera Funds Management LTD. | 195,212 | $0.71M | 0.1% | N/A | 0.308% |  |
| 2/18/2026 | Millennium Management LLC | 477,408 | $1.74M | 0.0% | -30.9% | 0.754% |  |
| 2/18/2026 | 683 Capital Management LLC | 1,390,000 | $5.07M | 0.2% | -9.3% | 2.197% |  |
| 2/17/2026 | Price T Rowe Associates Inc. MD | 1,926,140 | $7.03M | 0.0% | N/A | 3.044% |  |
| 2/17/2026 | T. Rowe Price Investment Management Inc. | 506,377 | $1.85M | 0.0% | N/A | 0.800% |  |
| 2/16/2026 | Squarepoint Ops LLC | 64,785 | $0.24M | 0.0% | +236.4% | 0.102% |  |
| 2/16/2026 | OMERS ADMINISTRATION Corp | 26,500 | $97K | 0.0% | N/A | 0.042% |  |
| 2/16/2026 | NEXTBio Capital Management LP | 3,149,907 | $11.50M | 6.7% | N/A | 4.978% |  |
| 2/13/2026 | Prosight Management LP | 2,381,502 | $8.69M | 1.8% | -56.3% | 3.763% |  |
| 2/13/2026 | Marshall Wace LLP | 489,912 | $1.79M | 0.0% | -25.4% | 0.774% |  |
| 2/13/2026 | The Manufacturers Life Insurance Company | 135,056 | $0.49M | 0.0% | N/A | 0.213% |  |
| 2/13/2026 | State Street Corp | 215,418 | $0.79M | 0.0% | +21.9% | 0.340% |  |
| 2/12/2026 | Jane Street Group LLC | 54,046 | $0.20M | 0.0% | -45.4% | 0.085% |  |
| 2/12/2026 | Renaissance Technologies LLC | 340,700 | $1.24M | 0.0% | +57.1% | 0.538% |  |
| 2/12/2026 | Dimensional Fund Advisors LP | 23,192 | $85K | 0.0% | N/A | 0.037% |  |
| 2/12/2026 | Keel Point LLC | 14,270 | $52K | 0.0% | -69.1% | 0.023% |  |
| 2/10/2026 | TD Asset Management Inc | 251,050 | $0.92M | 0.0% | N/A | 0.397% |  |
| 2/10/2026 | Goldman Sachs Group Inc. | 128,165 | $0.47M | 0.0% | +662.9% | 0.203% |  |
| 2/9/2026 | Geode Capital Management LLC | 618,277 | $2.26M | 0.0% | +32.1% | 0.977% |  |
| 2/5/2026 | Pinnacle Associates Ltd. | 1,350,638 | $4.93M | 0.1% | -2.7% | 2.134% |  |
| 1/16/2026 | Aberdeen Group plc | 531,177 | $1.94M | 0.0% | +462.1% | 0.839% |  |
| 1/6/2026 | Mallini Complete Financial Planning LLC | 22,632 | $83K | 0.1% | N/A | 0.036% |  |
| 12/16/2025 | Keel Point LLC | 46,173 | $0.11M | 0.0% | N/A | 0.073% |  |
| 11/17/2025 | Susquehanna International Group LLP | 68,116 | $0.16M | 0.0% | -65.3% | 0.108% |  |
| 11/17/2025 | Qube Research & Technologies Ltd | 15,951 | $38K | 0.0% | -71.2% | 0.025% |  |
| 11/17/2025 | Millennium Management LLC | 690,901 | $1.65M | 0.0% | -18.1% | 1.092% |  |
| 11/17/2025 | Bank of America Corp DE | 1,131,888 | $2.71M | 0.0% | +2,968.2% | 1.789% |  |
| 11/14/2025 | Virtu Financial LLC | 16,054 | $38K | 0.0% | N/A | 0.034% |  |
| 11/14/2025 | Orbimed Advisors LLC | 6,306,127 | $15.07M | 0.4% | N/A | 13.165% |  |
| 11/14/2025 | Two Sigma Investments LP | 408,598 | $0.98M | 0.0% | +431.1% | 0.853% |  |
| 11/14/2025 | Bridgeway Capital Management LLC | 42,300 | $0.10M | 0.0% | -54.2% | 0.088% |  |
| 11/14/2025 | Squarepoint Ops LLC | 19,260 | $46K | 0.0% | N/A | 0.040% |  |
| 11/14/2025 | Prosight Management LP | 5,451,195 | $13.03M | 3.0% | -17.9% | 11.380% |  |
| 11/13/2025 | Pinnacle Associates Ltd. | 1,388,723 | $3.32M | 0.0% | +1.8% | 2.899% |  |
| 11/7/2025 | Vanguard Group Inc. | 2,128,401 | $5.09M | 0.0% | -0.9% | 4.443% |  |
| 11/7/2025 | Aberdeen Group plc | 94,504 | $0.23M | 0.0% | N/A | 0.197% |  |
| 10/29/2025 | Turtle Creek Wealth Advisors LLC | 12,235 | $29K | 0.0% | N/A | 0.026% |  |
| 10/7/2025 | LBJ Family Wealth Advisors Ltd. | 82,177 | $0.20M | 0.1% | N/A | 0.172% |  |
| 8/15/2025 | Bridgeway Capital Management LLC | 92,300 | $73K | 0.0% | +147.5% | 0.193% |  |
| 8/15/2025 | Bank of America Corp DE | 36,891 | $29K | 0.0% | -63.0% | 0.077% |  |
| 8/15/2025 | 683 Capital Management LLC | 1,095,000 | $0.87M | 0.1% | +4.3% | 2.286% |  |
| 8/14/2025 | Jane Street Group LLC | 289,671 | $0.23M | 0.0% | +2,510.8% | 0.605% |  |
| 8/14/2025 | Qube Research & Technologies Ltd | 55,380 | $44K | 0.0% | N/A | 0.116% |  |
| 8/8/2025 | Geode Capital Management LLC | 467,959 | $0.37M | 0.0% | -49.9% | 0.977% |  |
| 8/4/2025 | Pinnacle Associates Ltd. | 1,363,723 | $1.08M | 0.0% | +4.9% | 2.847% |  |
| 8/1/2025 | Y Intercept Hong Kong Ltd | 123,172 | $98K | 0.0% | N/A | 0.257% |  |
| 6/27/2025 | Goldman Sachs Group Inc. | 102,313 | $97K | 0.0% | -57.5% | 0.214% |  |
| 5/21/2025 | Acadian Asset Management LLC | 257,345 | $0.24M | 0.0% | +27.6% | 0.537% |  |
| 5/16/2025 | Goldman Sachs Group Inc. | 102,313 | $97K | 0.0% | -57.5% | 0.214% |  |
| 5/16/2025 | Jacobs Levy Equity Management Inc. | 85,638 | $81K | 0.0% | N/A | 0.179% |  |
| 5/16/2025 | AQR Capital Management LLC | 43,169 | $41K | 0.0% | +265.4% | 0.090% |  |
| 5/16/2025 | ADAR1 Capital Management LLC | 102,156 | $97K | 0.0% | N/A | 0.213% |  |
| 5/12/2025 | Nuveen LLC | 53,038 | $50K | 0.0% | N/A | 0.111% |  |
| 5/6/2025 | Pinnacle Associates Ltd. | 1,299,723 | $1.24M | 0.0% | -1.9% | 2.713% |  |
| 2/17/2025 | Two Sigma Investments LP | 130,679 | $0.16M | 0.0% | -31.3% | 0.274% |  |
| 2/17/2025 | Two Sigma Advisers LP | 195,100 | $0.24M | 0.0% | -23.2% | 0.409% |  |
| 2/17/2025 | Redmile Group LLC | 5,539,724 | $6.70M | 0.5% | -1.3% | 11.604% |  |
| 2/17/2025 | Prosight Management LP | 6,638,935 | $8.03M | 2.2% | +15.1% | 13.906% |  |
| 2/17/2025 | Millennium Management LLC | 201,214 | $0.24M | 0.0% | +37.0% | 0.421% |  |
| 2/17/2025 | Deutsche Bank AG | 116,868 | $0.14M | 0.0% | +476.4% | 0.245% |  |
| 2/17/2025 | Bridgeway Capital Management LLC | 74,300 | $90K | 0.0% | -29.8% | 0.156% |  |
| 2/17/2025 | Bank of America Corp DE | 187,089 | $0.23M | 0.0% | +135.0% | 0.392% |  |
| 2/17/2025 | 683 Capital Management LLC | 1,050,000 | $1.27M | 0.1% | N/A | 2.199% |  |
| 2/14/2025 | Schonfeld Strategic Advisors LLC | 37,400 | $45K | 0.0% | N/A | 0.078% |  |
| 2/14/2025 | Northern Trust Corp | 353,616 | $0.43M | 0.0% | +9.2% | 0.741% |  |
| 2/14/2025 | Adage Capital Partners GP L.L.C. | 4,675,000 | $5.66M | 0.0% | +61.2% | 9.793% |  |
| 2/14/2025 | Dimensional Fund Advisors LP | 62,956 | $76K | 0.0% | -63.5% | 0.132% |  |
| 2/13/2025 | Zacks Investment Management | 21,044 | $25K | 0.0% | N/A | 0.044% |  |
| 2/13/2025 | Renaissance Technologies LLC | 28,100 | $34K | 0.0% | -88.8% | 0.059% |  |
| 2/12/2025 | Takeda Pharmaceutical Co. Ltd. | 515,619 | $0.62M | 2.3% | N/A | 1.080% |  |
| 2/12/2025 | JPMorgan Chase & Co. | 132,696 | $0.16M | 0.0% | +382.0% | 0.278% |  |
| 2/11/2025 | Virtu Financial LLC | 24,446 | $30K | 0.0% | N/A | 0.051% |  |
| 1/15/2025 | Ritholtz Wealth Management | 26,000 | $31K | 0.0% | -81.8% | 0.054% |  |
| 12/26/2024 | JPMorgan Chase & Co. | 27,533 | $96K | 0.0% | +63.2% | 0.058% |  |
| 11/19/2024 | Barclays PLC | 54,311 | $0.19M | 0.0% | +299.5% | 0.114% |  |
| 11/16/2024 | Geode Capital Management LLC | 912,202 | $3.18M | 0.0% | +0.9% | 1.911% |  |
| 11/15/2024 | Barclays PLC | 54,311 | $0.19M | 0.0% | +299.5% | 0.114% |  |
| 11/15/2024 | EP Wealth Advisors LLC | 41,167 | $0.14M | 0.0% | N/A | 0.086% |  |
| 11/15/2024 | Jane Street Group LLC | 25,705 | $90K | 0.0% | -46.9% | 0.054% |  |
| 11/15/2024 | State Street Corp | 766,410 | $2.68M | 0.0% | +7.8% | 1.606% |  |
| 11/15/2024 | Readystate Asset Management LP | 11,049 | $39K | 0.0% | N/A | 0.023% |  |
| 11/15/2024 | Benjamin Edwards Inc. | 17,520 | $61K | 0.0% | N/A | 0.037% |  |
| 11/15/2024 | Atom Investors LP | 10,141 | $35K | 0.0% | N/A | 0.021% |  |
| 11/14/2024 | MetLife Investment Management LLC | 24,596 | $86K | 0.0% | +129.1% | 0.052% |  |
| 11/13/2024 | FMR LLC | 7,159,090 | $24.99M | 0.0% | +0.4% | 14.999% |  |
| 11/8/2024 | Connor Clark & Lunn Investment Management Ltd. | 178,228 | $0.62M | 0.0% | +44.1% | 0.373% |  |
| 11/5/2024 | GSA Capital Partners LLP | 34,699 | $0.12M | 0.0% | N/A | 0.073% |  |
| 11/1/2024 | Villere ST Denis J & Co. LLC | 132,600 | $0.46M | 0.0% | +83.7% | 0.278% |  |
| 10/25/2024 | Pinnacle Associates Ltd. | 457,446 | $1.60M | 0.0% | -23.7% | 0.962% |  |
| 8/15/2024 | The Manufacturers Life Insurance Company | 17,425 | $67K | 0.0% | N/A | 0.037% |  |
| 8/14/2024 | Squarepoint Ops LLC | 47,975 | $0.19M | 0.0% | -17.8% | 0.101% |  |
| 8/14/2024 | Marshall Wace LLP | 69,042 | $0.27M | 0.0% | -10.9% | 0.145% |  |
| 8/9/2024 | Renaissance Technologies LLC | 392,010 | $1.51M | 0.0% | +83.1% | 0.821% |  |
| 8/9/2024 | Dimensional Fund Advisors LP | 69,062 | $0.27M | 0.0% | +8.5% | 0.145% |  |
| 8/8/2024 | American Century Companies Inc. | 47,367 | $0.18M | 0.0% | +25.4% | 0.100% |  |
| 8/6/2024 | Acadian Asset Management LLC | 44,193 | $0.17M | 0.0% | N/A | 0.093% |  |
| 8/1/2024 | Rhumbline Advisers | 47,245 | $0.18M | 0.0% | N/A | 0.099% |  |