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SPRB Insider Trading

Insider Ownership Percentage: 6.90%
Insider Buying (Last 12 Months): $4,584.96
Insider Selling (Last 12 Months): $4,918.98

Spruce Biosciences Insider Trading History Chart

This chart shows the insider buying and selling history at Spruce Biosciences by year and by quarter.

Skip ChartChart Data in Insider Trading History Table

Spruce Biosciences Share Price & Price History

Current Price: $58.22
Price Change: ▲ Price Increase of +4.64 (8.66%)
As of 02/24/2026 05:00 PM ET

This chart shows the closing price history over time for SPRB up to the past year.

Skip Chart and Table DataPrice Data in Insider Trading History Table
Days: 30 | 90 | 365

Spruce Biosciences Insider Trading History

Transaction DateInsider NameTitleBuy/SellNumber of SharesAverage Share PriceTotal TransactionShares Held After TransactionDetails
10/6/2025Parkman Healthcare Partners LlMajor ShareholderBuy256$17.91$4,584.961,307View SEC Filing Icon  
10/6/2025Parkman Healthcare Partners LlMajor ShareholderSell257$19.14$4,918.981,050View SEC Filing Icon  
3/20/2024Holdings A/S NovoMajor ShareholderSell4,799$54.75$262,745.2540,200View SEC Filing Icon  
3/18/2024Holdings A/S NovoMajor ShareholderSell11,226$57.75$648,301.5052,906View SEC Filing Icon  
3/14/2024Holdings A/S NovoMajor ShareholderSell25,497$66.75$1,701,924.7564,133View SEC Filing Icon  
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SEC Filings (Institutional Ownership Changes) for Spruce Biosciences (NASDAQ:SPRB)

91.71% of Spruce Biosciences stock is owned by institutions. Institutional ownership can be a sign of analyst confidence in the fundamentals of the stock.

Institutional Buying and Selling by Quarter

This chart shows the instiutional buying and selling at SPRB by year and by quarter.

Skip Institutional Buying and Selling Chart and Table DataRead Chart Data in Institutional Trading History Table

Spruce Biosciences Institutional Trading History

Reporting DateHedge FundShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
2/18/2026SkyView Investment Advisors LLC3,000$0.26M0.0%N/A0.280%Search for SEC Filing on Google Icon
2/18/2026Ikarian Capital LLC121,356$10.57M0.8%+810.3%11.342%Search for SEC Filing on Google Icon
2/18/2026Wellington Management Group LLP58,949$5.14M0.0%N/A5.509%Search for SEC Filing on Google Icon
2/18/2026Squadron Capital Management LLC70,000$6.10M2.6%N/A6.542%Search for SEC Filing on Google Icon
2/18/2026Superstring Capital Management LP12,137$1.06M0.6%N/A1.134%Search for SEC Filing on Google Icon
2/18/2026Balyasny Asset Management L.P.40,000$3.48M0.0%N/A3.738%Search for SEC Filing on Google Icon
2/18/2026Boothbay Fund Management LLC47,933$4.18M0.1%N/A4.480%Search for SEC Filing on Google Icon
2/17/2026Caligan Partners LP20,514$1.79M0.1%N/A1.917%Search for SEC Filing on Google Icon
2/17/2026ADAR1 Capital Management LLC58,000$5.05M0.4%N/A5.421%Search for SEC Filing on Google Icon
2/17/2026Schonfeld Strategic Advisors LLC24,767$2.16M0.0%N/A2.315%Search for SEC Filing on Google Icon
2/17/2026ExodusPoint Capital Management LP25,271$2.20M0.0%N/A2.362%Search for SEC Filing on Google Icon
2/13/2026Carlyle Group Inc.38,620$3.30M0.0%-98.7%3.609%Search for SEC Filing on Google Icon
2/13/2026Quinn Opportunity Partners LLC22,810$1.99M0.1%N/A2.132%Search for SEC Filing on Google Icon
2/13/2026Alyeska Investment Group L.P.51,671$4.50M0.0%N/A4.829%Search for SEC Filing on Google Icon
2/13/2026State Street Corp6,400$0.56M0.0%N/A0.598%Search for SEC Filing on Google Icon
2/9/2026Geode Capital Management LLC12,732$1.11M0.0%N/A1.190%Search for SEC Filing on Google Icon
11/14/2025Cable Car Capital LP26,666$0.24M0.1%N/A5.333%Search for SEC Filing on Google Icon
11/7/2025Carlyle Group Inc.2,896,518$24.77M0.6%N/A579.304%Search for SEC Filing on Google Icon
2/14/2025Boothbay Fund Management LLC288,800$0.12M0.0%N/A0.699%Search for SEC Filing on Google Icon
2/13/2025Renaissance Technologies LLC405,900$0.17M0.0%-33.4%0.983%Search for SEC Filing on Google Icon
8/16/2024Almitas Capital LLC396,506$0.21M0.1%N/A0.964%Search for SEC Filing on Google Icon
8/9/2024Renaissance Technologies LLC366,100$0.19M0.0%+35.1%0.890%Search for SEC Filing on Google Icon
8/6/2024Acadian Asset Management LLC1,367,997$0.71M0.0%+270.9%3.324%Search for SEC Filing on Google Icon
5/16/2024AWM Investment Company Inc.200,000$0.16M0.0%N/A0.486%Search for SEC Filing on Google Icon
5/10/2024Acadian Asset Management LLC368,831$0.29M0.0%N/A0.896%Search for SEC Filing on Google Icon
4/25/2024Rosalind Advisors Inc.1,508,419$1.19M1.1%-4.9%3.666%Search for SEC Filing on Google Icon
2/14/2024Superstring Capital Management LP118,814$0.35M0.2%N/A0.292%Search for SEC Filing on Google Icon
2/13/2024Armistice Capital LLC2,230,000$6.53M0.1%-27.0%5.478%Search for SEC Filing on Google Icon
2/12/2024AIGH Capital Management LLC2,123,863$6.22M2.5%+75.4%5.217%Search for SEC Filing on Google Icon
2/9/2024Worth Venture Partners LLC526,933$1.54M0.8%+74.4%1.294%Search for SEC Filing on Google Icon
11/15/2023Worth Venture Partners LLC302,074$0.68M0.4%+8.8%0.742%Search for SEC Filing on Google Icon
11/15/2023Armistice Capital LLC3,056,000$6.91M0.1%-12.6%7.507%Search for SEC Filing on Google Icon
11/13/2023AIGH Capital Management LLC1,211,000$2.74M1.3%+9.0%2.975%Search for SEC Filing on Google Icon
7/26/2023Privium Fund Management B.V.24,554$52K0.0%N/A0.062%Search for SEC Filing on Google Icon
5/15/2023AIGH Capital Management LLC1,104,000$2.37M0.9%N/A2.778%Search for SEC Filing on Google Icon
5/5/2023Carlyle Group Inc.2,896,518$6.40M0.2%N/A7.287%Search for SEC Filing on Google Icon
5/3/2023Privium Fund Management UK Ltd24,554$53K0.0%-51.3%0.062%Search for SEC Filing on Google Icon
5/1/2023Virtu Financial LLC13,722$30K0.0%N/A0.035%Search for SEC Filing on Google Icon
5/1/2023Marquette Asset Management LLC55,757$0.12M0.0%-18.4%0.140%Search for SEC Filing on Google Icon
4/27/2023RiverVest Venture Management LLC2,936,281$6.49M7.5%+36.7%7.387%Search for SEC Filing on Google Icon
2/13/2023BML Capital Management LLC221,830$0.24M0.2%N/A0.942%Search for SEC Filing on Google Icon
2/9/2023Privium Fund Management UK Ltd50,400$55K0.0%N/A0.214%Search for SEC Filing on Google Icon
1/12/2023Marquette Asset Management LLC68,357$75K0.0%+6.7%0.290%Search for SEC Filing on Google Icon
11/14/2022Ergoteles LLC23,032$32K0.0%-45.0%0.098%Search for SEC Filing on Google Icon
11/10/2022Abingworth LLP1,792,518$2.47M0.8%N/A7.608%Search for SEC Filing on Google Icon
10/18/2022Bailard Inc.21,166$29K0.0%N/A0.090%Search for SEC Filing on Google Icon
7/15/2022Marquette Asset Management LLC64,090$0.11M0.0%+56.9%0.273%Search for SEC Filing on Google Icon
2/10/2022Acadian Asset Management LLC71,756$0.32M0.0%N/A0.306%Search for SEC Filing on Google Icon
1/19/2022Marquette Asset Management LLC40,853$0.18M0.0%N/A0.174%Search for SEC Filing on Google Icon
Data available starting January 2016

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Spruce Biosciences logo
Spruce Biosciences, Inc., a biopharmaceutical company, focuses on developing and commercializing novel therapies for rare endocrine disorders. The company engages in developing tildacerfont, a non-steroidal therapy to enhance disease control and reduce steroid burden for patients suffering from congenital adrenal hyperplasia (CAH), which is in Phase 2b clinical trial; and to evaluate glucocorticoid reduction in adult patients with classic CAH that is Phase 2b clinical trial. It is also developing tildacerfont for the treatment of pediatric classic congenital adrenal hyperplasia in children that is in Phase 2 clinical trial; and for females with polycystic ovary syndrome, which is in Phase 2 clinical trial. Spruce Biosciences, Inc. has a license agreement with Eli Lilly and Company to research, develop, and commercialize compounds for various pharmaceutical uses; and collaboration and license agreement with Kaken Pharmaceutical Co. Ltd. to develop, manufacture, and commercialize tildacerfont for the treatment of CAH in Japan. The company was incorporated in 2014 and is headquartered in South San Francisco, California.
Read More on Spruce Biosciences

Today's Range

Now: $58.22
Low: $53.95
High: $60.00

50 Day Range

MA: $76.61
Low: $49.72
High: $90.70

52 Week Range

Now: $58.22
Low: $4.28
High: $240.00

Volume

34,787 shs

Average Volume

48,689 shs

Market Capitalization

$62.30 million

P/E Ratio

N/A

Dividend Yield

N/A

Beta

3.52

Who are the company insiders with the largest holdings of Spruce Biosciences?

Spruce Biosciences' top insider investors include:
  1. Holdings A/S Novo (Major Shareholder)
  2. Parkman Healthcare Partners Ll (Major Shareholder)
Learn More about top insider investors at Spruce Biosciences.

Who are the major institutional investors of Spruce Biosciences?

Spruce Biosciences' top institutional shareholders include:
  1. Ikarian Capital LLC — 11.34%
  2. Squadron Capital Management LLC — 6.54%
  3. Wellington Management Group LLP — 5.51%
  4. ADAR1 Capital Management LLC — 5.42%
  5. Alyeska Investment Group L.P. — 4.83%
  6. Boothbay Fund Management LLC — 4.48%
Learn More about top institutional investors of Spruce Biosciences stock.

Which institutional investors are selling Spruce Biosciences stock?

During the last quarter, SPRB stock was sold by these institutional investors:
  1. Carlyle Group Inc.

Which institutional investors are buying Spruce Biosciences stock?

Within the last quarter, SPRB stock was purchased by institutional investors including:
  1. Ikarian Capital LLC
  2. Squadron Capital Management LLC
  3. Wellington Management Group LLP
  4. ADAR1 Capital Management LLC
  5. Alyeska Investment Group L.P.
  6. Boothbay Fund Management LLC
  7. Balyasny Asset Management L.P.
  8. ExodusPoint Capital Management LP