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TSHA Insider Trading

Insider Ownership Percentage: 3.78%
Insider Buying (Last 12 Months): $2,062,500.00
Insider Selling (Last 12 Months): $2,341,905.72

Taysha Gene Therapies Insider Trading History Chart

This chart shows the insider buying and selling history at Taysha Gene Therapies by year and by quarter.

Skip ChartChart Data in Insider Trading History Table

Taysha Gene Therapies Share Price & Price History

Current Price: $5.06
Price Change: ▲ Price Increase of +0.57 (12.69%)
As of 12/4/2025 05:00 PM ET

This chart shows the closing price history over time for TSHA up to the past year.

Skip Chart and Table DataPrice Data in Insider Trading History Table
Days: 30 | 90 | 365

Taysha Gene Therapies Insider Trading History

Transaction DateInsider NameTitleBuy/SellNumber of SharesAverage Share PriceTotal TransactionShares Held After TransactionDetails
12/1/2025Sukumar NagendranInsiderSell260,047$4.51$1,172,811.971,006,439View SEC Filing Icon  
11/28/2025Sukumar NagendranInsiderSell110,125$4.75$523,093.751,006,439View SEC Filing Icon  
9/10/2025Sukumar NagendranInsiderSell200,000$3.23$646,000.001,006,439View SEC Filing Icon  
5/30/2025Paul B. ManningMajor ShareholderBuy750,000$2.75$2,062,500.002,841,704View SEC Filing Icon  
6/27/2024Paul B. ManningMajor ShareholderBuy1,333,333$2.25$2,999,999.251,333,333View SEC Filing Icon  
11/17/2023Paul B. ManningMajor ShareholderBuy100,000$1.63$163,000.0016,566,667View SEC Filing Icon  
8/24/2023Kamran AlamCFOSell33,000$2.33$76,890.00258,042View SEC Filing Icon  
8/16/2023John A Stalfort IIIDirectorBuy388,889$0.90$350,000.10999,381View SEC Filing Icon  
8/16/2023Paul B. ManningMajor ShareholderBuy16,466,667$0.90$14,820,000.3016,466,667View SEC Filing Icon  
8/16/2023Sean P. NolanCEOBuy444,444$0.90$399,999.601,535,545View SEC Filing Icon  
7/12/2023R.A. Session, IIMajor ShareholderSell80,528$0.71$57,174.888,877,091View SEC Filing Icon  
6/22/2023R.A. Session, IIMajor ShareholderSell10,508$0.70$7,355.608,975,719View SEC Filing Icon  
6/20/2023R.A. Session, IIMajor ShareholderSell295,653$0.71$209,913.639,125,189View SEC Filing Icon  
5/16/2023Sukumar NagendranInsiderBuy5,000$0.68$3,400.0034,226View SEC Filing Icon  
See Full Table

SEC Filings (Institutional Ownership Changes) for Taysha Gene Therapies (NASDAQ:TSHA)

77.70% of Taysha Gene Therapies stock is owned by institutions. Institutional ownership can be a sign of analyst confidence in the fundamentals of the stock.

Institutional Buying and Selling by Quarter

This chart shows the instiutional buying and selling at TSHA by year and by quarter.

Skip Institutional Buying and Selling Chart and Table DataRead Chart Data in Institutional Trading History Table

Taysha Gene Therapies Institutional Trading History

Reporting DateHedge FundShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
11/21/2025CIBC Bancorp USA Inc.22,643$74K0.0%N/A0.008%Search for SEC Filing on Google Icon
11/17/2025Woodline Partners LP500,000$1.64M0.0%-50.0%0.183%Search for SEC Filing on Google Icon
11/17/2025Sender Co & Partners Inc.27,121$89K0.0%N/A0.010%Search for SEC Filing on Google Icon
11/17/2025Vestal Point Capital LP5,500,000$17.99M0.8%+83.3%2.008%Search for SEC Filing on Google Icon
11/17/2025Polar Capital Holdings Plc5,293,879$17.31M0.1%+5.9%1.933%Search for SEC Filing on Google Icon
11/17/2025MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.111,024$0.36M0.0%+15.0%0.041%Search for SEC Filing on Google Icon
11/17/2025Jain Global LLC52,608$0.17M0.0%N/A0.019%Search for SEC Filing on Google Icon
11/17/2025Granahan Investment Management LLC1,116,629$3.65M0.1%+16.5%0.408%Search for SEC Filing on Google Icon
11/17/2025Brevan Howard Capital Management LP46,643$0.15M0.0%N/A0.017%Search for SEC Filing on Google Icon
11/17/2025Bank of America Corp DE1,307,287$4.28M0.0%+78.9%0.477%Search for SEC Filing on Google Icon
11/17/2025Boothbay Fund Management LLC415,607$1.36M0.0%N/A0.152%Search for SEC Filing on Google Icon
11/17/2025Ally Bridge Group NY LLC1,898,112$6.21M3.8%N/A0.693%Search for SEC Filing on Google Icon
11/17/2025Anson Funds Management LP603,500$1.97M0.2%-24.9%0.220%Search for SEC Filing on Google Icon
11/14/2025Virtu Financial LLC48,123$0.16M0.0%N/A0.018%Search for SEC Filing on Google Icon
11/14/2025ADAR1 Capital Management LLC2,835,680$9.27M0.9%-5.8%1.035%Search for SEC Filing on Google Icon
11/14/2025Acuta Capital Partners LLC454,827$1.49M1.5%-6.4%0.166%Search for SEC Filing on Google Icon
11/14/2025Two Sigma Investments LP66,105$0.22M0.0%+102.3%0.024%Search for SEC Filing on Google Icon
11/14/2025Squarepoint Ops LLC198,352$0.65M0.0%+97.9%0.072%Search for SEC Filing on Google Icon
11/14/2025Arrowpoint Investment Partners Singapore Pte. Ltd.12,200$40K0.0%N/A0.004%Search for SEC Filing on Google Icon
11/13/2025UBS Group AG639,356$2.09M0.0%+144.7%0.233%Search for SEC Filing on Google Icon
11/13/2025BNP Paribas Financial Markets46,034$0.15M0.0%+147.6%0.017%Search for SEC Filing on Google Icon
11/13/2025Legal & General Group Plc23,149$76K0.0%+25.8%0.008%Search for SEC Filing on Google Icon
11/13/2025Russell Investments Group Ltd.18,165$59K0.0%N/A0.007%Search for SEC Filing on Google Icon
11/13/2025Jefferies Financial Group Inc.2,156,642$7.05M0.0%-79.1%0.787%Search for SEC Filing on Google Icon
11/12/2025Barclays PLC5,148,112$16.83M0.0%+1,042.8%1.879%Search for SEC Filing on Google Icon
11/12/2025Dimensional Fund Advisors LP345,163$1.13M0.0%N/A0.126%Search for SEC Filing on Google Icon
11/12/2025Rafferty Asset Management LLC239,785$0.78M0.0%+102.0%0.088%Search for SEC Filing on Google Icon
11/12/2025R Squared Ltd16,094$53K0.0%N/A0.006%Search for SEC Filing on Google Icon
11/12/2025Xponance Inc.16,575$54K0.0%+29.1%0.006%Search for SEC Filing on Google Icon
11/12/2025Intech Investment Management LLC68,626$0.22M0.0%-16.5%0.025%Search for SEC Filing on Google Icon
11/10/2025Palumbo Wealth Management LLC157,353$0.52M0.1%N/A0.057%Search for SEC Filing on Google Icon
11/10/2025AXQ Capital LP49,677$0.16M0.1%-12.8%0.018%Search for SEC Filing on Google Icon
11/10/2025Quantum Private Wealth LLC822,076$2.69M0.8%+0.7%0.300%Search for SEC Filing on Google Icon
11/10/2025China Universal Asset Management Co. Ltd.47,817$0.16M0.0%-9.0%0.017%Search for SEC Filing on Google Icon
11/7/2025Readystate Asset Management LP161,972$0.53M0.0%N/A0.059%Search for SEC Filing on Google Icon
11/7/2025GSA Capital Partners LLP477,749$1.56M0.1%+969.0%0.174%Search for SEC Filing on Google Icon
11/7/2025Vanguard Group Inc.12,849,613$42.02M0.0%+17.9%4.691%Search for SEC Filing on Google Icon
11/7/2025JPMorgan Chase & Co.296,244$0.97M0.0%+33.1%0.108%Search for SEC Filing on Google Icon
11/6/2025Allegheny Financial Group15,000$49K0.0%N/A0.005%Search for SEC Filing on Google Icon
11/6/2025Rhumbline Advisers288,859$0.95M0.0%+23.8%0.106%Search for SEC Filing on Google Icon
11/6/2025Tybourne Capital Management HK Ltd.3,700,000$12.10M39.1%-9.6%1.356%Search for SEC Filing on Google Icon
11/6/2025Profund Advisors LLC53,366$0.18M0.0%+100.6%0.020%Search for SEC Filing on Google Icon
11/4/2025Principal Financial Group Inc.16,251$53K0.0%+33.6%0.006%Search for SEC Filing on Google Icon
11/3/2025New York State Common Retirement Fund67,600$0.22M0.0%+220.4%0.025%Search for SEC Filing on Google Icon
10/23/2025SG Americas Securities LLC32,949$0.11M0.0%-93.3%0.012%Search for SEC Filing on Google Icon
10/17/2025Ethic Inc.25,784$84K0.0%-7.8%0.009%Search for SEC Filing on Google Icon
10/16/2025Rice Hall James & Associates LLC578,118$1.89M0.1%N/A0.212%Search for SEC Filing on Google Icon
10/9/2025Voya Investment Management LLC36,500$0.12M0.0%-22.6%0.013%Search for SEC Filing on Google Icon
10/7/2025ST Germain D J Co. Inc.9,633$32K0.0%+81.8%0.004%Search for SEC Filing on Google Icon
8/28/2025China Universal Asset Management Co. Ltd.52,527$0.12M0.0%+27.7%0.019%Search for SEC Filing on Google Icon
8/19/2025Marex Group plc12,500$29K0.0%N/A0.006%Search for SEC Filing on Google Icon
8/15/2025Tower Research Capital LLC TRC 17,606$41K0.0%+156.5%0.008%Search for SEC Filing on Google Icon
8/15/2025E Fund Management Co. Ltd.13,214$31K0.0%N/A0.006%Search for SEC Filing on Google Icon
8/15/2025Rafferty Asset Management LLC118,683$0.27M0.0%N/A0.055%Search for SEC Filing on Google Icon
8/15/2025Octagon Capital Advisors LP12,592,500$29.09M6.4%+17.7%5.866%Search for SEC Filing on Google Icon
8/15/2025Militia Capital Partners LP66,800$0.15M0.1%N/A0.031%Search for SEC Filing on Google Icon
8/15/2025Engineers Gate Manager LP64,617$0.15M0.0%N/A0.030%Search for SEC Filing on Google Icon
8/15/2025BNP Paribas Financial Markets18,591$43K0.0%+51.9%0.009%Search for SEC Filing on Google Icon
8/15/2025Bank of America Corp DE730,728$1.69M0.0%+14.7%0.340%Search for SEC Filing on Google Icon
8/15/2025Adage Capital Partners GP L.L.C.4,839,000$11.18M0.0%N/A2.254%Search for SEC Filing on Google Icon
8/14/2025MPM Bioimpact LLC2,953,562$6.82M1.2%N/A1.376%Search for SEC Filing on Google Icon
8/14/2025Acuta Capital Partners LLC485,669$1.12M1.6%N/A0.226%Search for SEC Filing on Google Icon
8/14/2025MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.96,543$0.22M0.0%-6.3%0.045%Search for SEC Filing on Google Icon
8/14/2025Stempoint Capital LP1,203,941$2.78M0.9%N/A0.561%Search for SEC Filing on Google Icon
8/14/2025B Group Inc.1,800,556$4.16M3.2%+43.4%0.839%Search for SEC Filing on Google Icon
8/14/2025Daiwa Securities Group Inc.23,841$55K0.0%+3,350.2%0.011%Search for SEC Filing on Google Icon
8/13/2025Affinity Asset Advisors LLC200,000$0.46M0.1%N/A0.093%Search for SEC Filing on Google Icon
8/13/2025Marshall Wace LLP79,498$0.18M0.0%N/A0.037%Search for SEC Filing on Google Icon
8/13/2025Invesco Ltd.203,671$0.47M0.0%+27.4%0.095%Search for SEC Filing on Google Icon
8/13/2025OMERS ADMINISTRATION Corp72,900$0.17M0.0%N/A0.034%Search for SEC Filing on Google Icon
8/13/2025Virtus Investment Advisers LLC35,484$82K0.0%-51.4%0.017%Search for SEC Filing on Google Icon
8/13/2025Quadrature Capital Ltd161,940$0.37M0.0%N/A0.075%Search for SEC Filing on Google Icon
8/12/2025XTX Topco Ltd320,737$0.74M0.0%+57.9%0.149%Search for SEC Filing on Google Icon
8/12/2025Jefferies Financial Group Inc.10,313,733$23.83M0.2%+4,105.3%4.805%Search for SEC Filing on Google Icon
8/12/2025Prudential Financial Inc.22,790$53K0.0%+50.5%0.011%Search for SEC Filing on Google Icon
8/12/2025Quantum Private Wealth LLC815,976$1.89M0.6%+3.1%0.380%Search for SEC Filing on Google Icon
8/12/2025Rhumbline Advisers233,256$0.54M0.0%+13.5%0.109%Search for SEC Filing on Google Icon
8/12/2025Franklin Resources Inc.108,399$0.25M0.0%-6.7%0.050%Search for SEC Filing on Google Icon
8/12/2025JPMorgan Chase & Co.222,649$0.51M0.0%-77.8%0.104%Search for SEC Filing on Google Icon
8/8/2025Intech Investment Management LLC82,195$0.19M0.0%-17.7%0.038%Search for SEC Filing on Google Icon
8/8/2025Creative Planning51,981$0.12M0.0%-33.6%0.024%Search for SEC Filing on Google Icon
8/8/2025SG Americas Securities LLC493,301$1.14M0.0%N/A0.230%Search for SEC Filing on Google Icon
8/8/2025Geode Capital Management LLC3,793,572$8.77M0.0%+3.5%1.767%Search for SEC Filing on Google Icon
8/7/2025Profund Advisors LLC26,599$61K0.0%N/A0.012%Search for SEC Filing on Google Icon
8/7/2025Mitsubishi UFJ Asset Management Co. Ltd.80,571$0.19M0.0%N/A0.038%Search for SEC Filing on Google Icon
8/7/2025Los Angeles Capital Management LLC117,740$0.27M0.0%-17.6%0.055%Search for SEC Filing on Google Icon
8/1/2025May Hill Capital LLC16,051$37K0.0%N/A0.007%Search for SEC Filing on Google Icon
8/1/2025Tybourne Capital Management HK Ltd.4,095,000$9.46M27.4%+10.7%1.908%Search for SEC Filing on Google Icon
7/30/2025Ethic Inc.27,975$67K0.0%N/A0.013%Search for SEC Filing on Google Icon
7/29/2025Chicago Partners Investment Group LLC163,766$0.38M0.0%+40.5%0.076%Search for SEC Filing on Google Icon
6/27/2025Goldman Sachs Group Inc.359,007$0.50M0.0%-62.9%0.167%Search for SEC Filing on Google Icon
5/29/2025Rhumbline Advisers205,462$0.29M0.0%+7.0%0.096%Search for SEC Filing on Google Icon
5/23/2025Siren L.L.C.6,514,737$9.06M0.5%-1.3%3.177%Search for SEC Filing on Google Icon
5/16/2025Woodline Partners LP858,254$1.19M0.0%-16.5%0.419%Search for SEC Filing on Google Icon
5/16/2025Octagon Capital Advisors LP10,700,000$14.87M1.6%+2.4%5.218%Search for SEC Filing on Google Icon
5/16/2025Goldman Sachs Group Inc.359,007$0.50M0.0%-62.9%0.175%Search for SEC Filing on Google Icon
5/16/2025MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.103,074$0.14M0.0%-5.1%0.050%Search for SEC Filing on Google Icon
5/16/2025Granahan Investment Management LLC1,640,793$2.28M0.1%+0.3%0.800%Search for SEC Filing on Google Icon
5/16/2025AQR Capital Management LLC107,899$0.15M0.0%+325.6%0.053%Search for SEC Filing on Google Icon
5/16/2025ADAR1 Capital Management LLC1,066,309$1.48M0.3%+500.0%0.520%Search for SEC Filing on Google Icon
Data available starting January 2016

See Full Table
Taysha Gene Therapies logo
Taysha Gene Therapies, Inc., a gene therapy company, focuses on developing and commercializing adeno-associated virus-based gene therapies for the treatment of monogenic diseases of the central nervous system. It primarily develops TSHA-120 for the treatment of giant axonal neuropathy; TSHA-102 for the treatment of Rett syndrome; TSHA-121 for the treatment of CLN7 disease; TSHA-118 for the treatment of CLN1 disease; TSHA-105 for the treatment of for SLC13A5 deficiency; TSHA-113 for the treatment of tauopathies; TSHA-106 for the treatment of angelman syndrome; TSHA-114 for the treatment of fragile X syndrome; and TSHA-101 for the treatment of GM2 gangliosidosis. Taysha Gene Therapies, Inc. has a strategic partnership with The University of Texas Southwestern Medical Center. Taysha Gene Therapies, Inc. was incorporated in 2019 and is headquartered in Dallas, Texas.
Read More on Taysha Gene Therapies

Today's Range

Now: $5.06
Low: $4.65
High: $5.09

50 Day Range

MA: $4.49
Low: $3.16
High: $5.34

52 Week Range

Now: $5.06
Low: $1.05
High: $5.51

Volume

5,620,888 shs

Average Volume

3,238,682 shs

Market Capitalization

$1.39 billion

P/E Ratio

N/A

Dividend Yield

N/A

Beta

1.06

Who are the company insiders with the largest holdings of Taysha Gene Therapies?

Taysha Gene Therapies' top insider investors include:
  1. Paul B Manning (Major Shareholder)
  2. Sukumar Nagendran (Insider)
Learn More about top insider investors at Taysha Gene Therapies.

Who are the major institutional investors of Taysha Gene Therapies?

Taysha Gene Therapies' top institutional investors include:
  1. Vanguard Group Inc. — 4.69%
  2. Vestal Point Capital LP — 2.01%
  3. Polar Capital Holdings Plc — 1.93%
  4. Barclays PLC — 1.88%
  5. Tybourne Capital Management HK Ltd. — 1.36%
  6. ADAR1 Capital Management LLC — 1.04%
Learn More about top institutional investors of Taysha Gene Therapies stock.

Which institutional investors are selling Taysha Gene Therapies stock?

In the last quarter, TSHA stock was sold by these institutional investors:
  1. Jefferies Financial Group Inc.
  2. Woodline Partners LP
  3. SG Americas Securities LLC
  4. Tybourne Capital Management HK Ltd.
  5. Anson Funds Management LP
  6. ADAR1 Capital Management LLC
  7. Acuta Capital Partners LLC
  8. Intech Investment Management LLC

Which institutional investors are buying Taysha Gene Therapies stock?

During the previous quarter, TSHA stock was bought by institutional investors including:
  1. Barclays PLC
  2. Vestal Point Capital LP
  3. Vanguard Group Inc.
  4. Ally Bridge Group NY LLC
  5. Rice Hall James & Associates LLC
  6. Bank of America Corp DE
  7. GSA Capital Partners LLP
  8. Boothbay Fund Management LLC