| 2/19/2026 | Invesco Ltd. | 498,926 | $6.25M | 0.0% | +3.3% | 0.389% |  |
| 2/18/2026 | KVP Capital Advisors LP | 414,000 | $5.18M | 5.0% | N/A | 0.323% |  |
| 2/18/2026 | XTX Topco Ltd | 83,818 | $1.05M | 0.0% | N/A | 0.065% |  |
| 2/18/2026 | Wellington Management Group LLP | 3,403,990 | $42.62M | 0.0% | +4.6% | 2.655% |  |
| 2/18/2026 | Tudor Investment Corp ET AL | 68,481 | $0.86M | 0.0% | N/A | 0.053% |  |
| 2/18/2026 | Sphera Funds Management LTD. | 598,534 | $7.49M | 1.4% | -22.6% | 0.467% |  |
| 2/18/2026 | Superstring Capital Management LP | 148,292 | $1.86M | 1.0% | N/A | 0.116% |  |
| 2/18/2026 | Orbimed Advisors LLC | 3,190,700 | $39.95M | 0.8% | -3.6% | 2.488% |  |
| 2/18/2026 | Opaleye Management Inc. | 345,100 | $4.32M | 0.6% | -11.5% | 0.269% |  |
| 2/18/2026 | Millennium Management LLC | 570,226 | $7.14M | 0.0% | -21.6% | 0.445% |  |
| 2/18/2026 | Artia Global Partners LP | 2,013,602 | $25.21M | 3.5% | +0.7% | 1.570% |  |
| 2/18/2026 | Balyasny Asset Management L.P. | 174,641 | $2.19M | 0.0% | -72.1% | 0.136% |  |
| 2/17/2026 | Logos Global Management LP | 1,550,000 | $19.41M | 1.2% | -29.5% | 1.209% |  |
| 2/17/2026 | Viking Global Investors LP | 3,198,644 | $40.05M | 0.1% | -37.6% | 2.494% |  |
| 2/17/2026 | AQR Capital Management LLC | 29,202 | $0.37M | 0.0% | -31.8% | 0.023% |  |
| 2/17/2026 | Abel Hall LLC | 10,191 | $0.13M | 0.0% | N/A | 0.008% |  |
| 2/17/2026 | MPM Bioimpact LLC | 3,287,087 | $41.15M | 4.7% | -3.5% | 2.563% |  |
| 2/17/2026 | Price T Rowe Associates Inc. MD | 50,273 | $0.63M | 0.0% | +7.3% | 0.039% |  |
| 2/17/2026 | California State Teachers Retirement System | 83,788 | $1.05M | 0.0% | +2.6% | 0.065% |  |
| 2/17/2026 | Diadema Partners LP | 97,184 | $1.22M | 0.2% | +13.2% | 0.076% |  |
| 2/17/2026 | Russell Investments Group Ltd. | 59,444 | $0.74M | 0.0% | +5.3% | 0.046% |  |
| 2/17/2026 | State of Wisconsin Investment Board | 120,566 | $1.51M | 0.0% | -2.2% | 0.094% |  |
| 2/17/2026 | Fred Alger Management LLC | 157,980 | $1.98M | 0.0% | -17.3% | 0.123% |  |
| 2/17/2026 | Royal Bank of Canada | 33,119 | $0.42M | 0.0% | -80.4% | 0.026% |  |
| 2/17/2026 | Persistent Asset Partners Ltd | 45,830 | $0.57M | 0.3% | +132.8% | 0.036% |  |
| 2/16/2026 | Verition Fund Management LLC | 32,119 | $0.40M | 0.0% | N/A | 0.025% |  |
| 2/16/2026 | Panagora Asset Management Inc. | 693,001 | $8.68M | 0.0% | +21.5% | 0.540% |  |
| 2/16/2026 | Kennedy Capital Management LLC | 56,269 | $0.70M | 0.0% | +2.4% | 0.044% |  |
| 2/16/2026 | Dymon Asia Capital Singapore PTE. LTD. | 20,000 | $0.25M | 0.0% | N/A | 0.016% |  |
| 2/16/2026 | Eventide Asset Management LLC | 2,622,306 | $32.83M | 0.5% | +89.8% | 2.045% |  |
| 2/16/2026 | Barclays PLC | 582,653 | $7.30M | 0.0% | +168.6% | 0.454% |  |
| 2/13/2026 | Marshall Wace LLP | 4,580,548 | $57.35M | 0.1% | -5.4% | 3.572% |  |
| 2/13/2026 | The Manufacturers Life Insurance Company | 27,937 | $0.35M | 0.0% | -5.7% | 0.022% |  |
| 2/13/2026 | Affinity Asset Advisors LLC | 2,150,172 | $26.92M | 1.5% | -23.2% | 1.677% |  |
| 2/13/2026 | Rubric Capital Management LP | 3,766,749 | $47.16M | 0.6% | -55.9% | 2.937% |  |
| 2/13/2026 | Stifel Financial Corp | 28,288 | $0.35M | 0.0% | +23.5% | 0.022% |  |
| 2/13/2026 | Hudson Bay Capital Management LP | 75,000 | $0.94M | 0.0% | N/A | 0.058% |  |
| 2/13/2026 | Rafferty Asset Management LLC | 16,499 | $0.21M | 0.0% | +21.6% | 0.013% |  |
| 2/13/2026 | Siren L.L.C. | 2,286,867 | $28.63M | 0.9% | -9.9% | 1.783% |  |
| 2/13/2026 | Charles Schwab Investment Management Inc. | 836,800 | $10.48M | 0.0% | +3.8% | 0.653% |  |
| 2/13/2026 | State Street Corp | 2,435,000 | $30.49M | 0.0% | +9.7% | 1.899% |  |
| 2/13/2026 | Vontobel Holding Ltd. | 10,764 | $0.14M | 0.0% | -50.8% | 0.008% |  |
| 2/13/2026 | UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 140,733 | $1.76M | 0.0% | +20.8% | 0.110% |  |
| 2/13/2026 | Wells Fargo & Company MN | 101,279 | $1.27M | 0.0% | +81.9% | 0.079% |  |
| 2/12/2026 | HRT Financial LP | 125,104 | $1.57M | 0.0% | N/A | 0.098% |  |
| 2/12/2026 | Dimensional Fund Advisors LP | 36,510 | $0.46M | 0.0% | -11.9% | 0.028% |  |
| 2/12/2026 | AlphaCentric Advisors LLC | 22,667 | $0.28M | 0.3% | N/A | 0.018% |  |
| 2/12/2026 | Informed Momentum Co LLC | 541,242 | $6.78M | 0.8% | -1.5% | 0.422% |  |
| 2/12/2026 | Steward Partners Investment Advisory LLC | 44,095 | $0.55M | 0.0% | +39.6% | 0.034% |  |
| 2/12/2026 | Campbell & CO Investment Adviser LLC | 71,097 | $0.89M | 0.0% | +185.7% | 0.055% |  |
| 2/12/2026 | Swiss National Bank | 168,200 | $2.11M | 0.0% | +4.0% | 0.131% |  |
| 2/11/2026 | Deutsche Bank AG | 70,833 | $0.89M | 0.0% | +37.2% | 0.055% |  |
| 2/11/2026 | Fox Run Management L.L.C. | 31,346 | $0.39M | 0.1% | N/A | 0.024% |  |
| 2/11/2026 | LPL Financial LLC | 52,960 | $0.66M | 0.0% | +30.9% | 0.041% |  |
| 2/11/2026 | Erste Asset Management GmbH | 90,000 | $1.15M | 0.0% | N/A | 0.070% |  |
| 2/11/2026 | Hilton Head Capital Partners LLC | 3,206 | $40K | 0.0% | N/A | 0.003% |  |
| 2/11/2026 | BIT Capital GmbH | 130,000 | $1.63M | 0.1% | +1,829.1% | 0.101% |  |
| 2/10/2026 | Goldman Sachs Group Inc. | 1,056,891 | $13.23M | 0.0% | +34.2% | 0.824% |  |
| 2/10/2026 | AXQ Capital LP | 22,204 | $0.28M | 0.1% | +43.0% | 0.017% |  |
| 2/10/2026 | Intech Investment Management LLC | 29,070 | $0.36M | 0.0% | +14.8% | 0.023% |  |
| 2/9/2026 | Kingsview Wealth Management LLC | 10,638 | $0.13M | 0.0% | N/A | 0.008% |  |
| 2/9/2026 | Geode Capital Management LLC | 2,412,885 | $30.21M | 0.0% | +8.6% | 1.882% |  |
| 2/9/2026 | Flputnam Investment Management Co. | 1,053,427 | $13.19M | 0.2% | +0.5% | 0.822% |  |
| 2/9/2026 | Sectoral Asset Management Inc. | 84,255 | $1.06M | 0.8% | -20.5% | 0.066% |  |
| 2/6/2026 | ProShare Advisors LLC | 22,269 | $0.28M | 0.0% | +15.3% | 0.017% |  |
| 2/4/2026 | Nan Fung Trinity HK Ltd. | 917,450 | $11.49M | 0.9% | +924.2% | 0.715% |  |
| 2/3/2026 | F m Investments LLC | 241,483 | $3.02M | 0.1% | N/A | 0.188% |  |
| 2/2/2026 | Strs Ohio | 23,700 | $0.30M | 0.0% | -26.6% | 0.018% |  |
| 2/2/2026 | Oppenheimer & Co. Inc. | 100,698 | $1.26M | 0.0% | +2.1% | 0.079% |  |
| 1/30/2026 | Chapin Davis Inc. | 20,100 | $0.25M | 0.1% | -42.7% | 0.016% |  |
| 1/29/2026 | Comerica Bank | 83,027 | $1.04M | 0.0% | +19,481.8% | 0.065% |  |
| 1/29/2026 | Pictet Asset Management Holding SA | 1,532,013 | $19.18M | 0.0% | +13,507.0% | 1.195% |  |
| 1/29/2026 | UBS Group AG | 274,628 | $3.44M | 0.0% | -8.0% | 0.214% |  |
| 1/29/2026 | Vanguard Group Inc. | 6,434,655 | $80.56M | 0.0% | +10.4% | 5.018% |  |
| 1/29/2026 | NBC Securities Inc. | 17,000 | $0.21M | 0.0% | +750.0% | 0.013% |  |
| 1/28/2026 | Peregrine Capital Management LLC | 507,685 | $6.36M | 0.2% | -18.2% | 0.396% |  |
| 1/27/2026 | Zurcher Kantonalbank Zurich Cantonalbank | 46,681 | $0.58M | 0.0% | +85.4% | 0.036% |  |
| 1/26/2026 | Mirae Asset Global Investments Co. Ltd. | 6,231 | $78K | 0.0% | +32.3% | 0.005% |  |
| 1/9/2026 | SG Americas Securities LLC | 124,562 | $1.56M | 0.0% | +93.0% | 0.097% |  |
| 1/9/2026 | Diversified Trust Co. | 20,984 | $0.26M | 0.0% | +14.6% | 0.016% |  |
| 12/1/2025 | Cantor Fitzgerald L. P. | 50,861 | $0.47M | 0.0% | -49.1% | 0.040% |  |
| 11/17/2025 | Woodline Partners LP | 100,282 | $0.92M | 0.0% | -97.5% | 0.078% |  |
| 11/17/2025 | Vivo Capital LLC | 5,094,668 | $46.62M | 3.8% | +13.5% | 3.973% |  |
| 11/17/2025 | Velan Capital Investment Management LP | 205,000 | $1.88M | 1.8% | N/A | 0.160% |  |
| 11/17/2025 | Qube Research & Technologies Ltd | 651,679 | $5.96M | 0.0% | +45.5% | 0.508% |  |
| 11/17/2025 | Millennium Management LLC | 727,596 | $6.66M | 0.0% | +362.7% | 0.567% |  |
| 11/17/2025 | MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 40,625 | $0.37M | 0.0% | -2.2% | 0.032% |  |
| 11/17/2025 | Fred Alger Management LLC | 191,045 | $1.75M | 0.0% | +221.5% | 0.149% |  |
| 11/17/2025 | Cantor Fitzgerald L. P. | 50,861 | $0.47M | 0.0% | -49.1% | 0.040% |  |
| 11/17/2025 | Bank of America Corp DE | 1,836,839 | $16.81M | 0.0% | +67.4% | 1.432% |  |
| 11/17/2025 | Alliancebernstein L.P. | 4,292,451 | $39.28M | 0.0% | +0.3% | 3.347% |  |
| 11/14/2025 | Creative Planning | 26,175 | $0.24M | 0.0% | +29.3% | 0.021% |  |
| 11/14/2025 | Viking Global Investors LP | 5,128,875 | $46.93M | 0.1% | +232.4% | 4.212% |  |
| 11/14/2025 | Raymond James Financial Inc. | 1,411,037 | $12.91M | 0.0% | +31.1% | 1.159% |  |
| 11/14/2025 | California State Teachers Retirement System | 81,697 | $0.75M | 0.0% | +1,716.7% | 0.067% |  |
| 11/14/2025 | Zurcher Kantonalbank Zurich Cantonalbank | 25,178 | $0.23M | 0.0% | +877.4% | 0.021% |  |
| 11/14/2025 | UBS AM A Distinct Business Unit of UBS Asset Management Americas LLC | 116,477 | $1.07M | 0.0% | N/A | 0.096% |  |
| 11/14/2025 | Wellington Management Group LLP | 3,253,888 | $29.77M | 0.0% | +1,792.0% | 2.672% |  |
| 11/14/2025 | Pivotal bioVenture Partners Investment Advisor LLC | 1,256,782 | $11.50M | 6.6% | +9.7% | 1.032% |  |
| 11/13/2025 | Marshall Wace LLP | 4,841,751 | $44.30M | 0.0% | +95.4% | 3.976% |  |