| 3/3/2026 | Caitong International Asset Management Co. Ltd | 2,997 | $79K | 0.0% | N/A | 0.006% |  |
| 2/26/2026 | Seven Fleet Capital Management LP | 79,560 | $2.09M | 1.6% | N/A | 0.149% |  |
| 2/19/2026 | Invesco Ltd. | 129,435 | $3.40M | 0.0% | +734.5% | 0.243% |  |
| 2/18/2026 | XTX Topco Ltd | 30,414 | $0.80M | 0.0% | -9.8% | 0.057% |  |
| 2/18/2026 | VARCOV Co. | 9,708 | $0.26M | 0.1% | N/A | 0.018% |  |
| 2/18/2026 | Virtus Investment Advisers LLC | 11,756 | $0.31M | 0.1% | +6.7% | 0.022% |  |
| 2/18/2026 | Wellington Management Group LLP | 104,305 | $2.74M | 0.0% | +25.9% | 0.195% |  |
| 2/18/2026 | Superstring Capital Management LP | 58,677 | $1.54M | 0.8% | N/A | 0.110% |  |
| 2/18/2026 | Millennium Management LLC | 114,388 | $3.01M | 0.0% | -20.6% | 0.214% |  |
| 2/18/2026 | Janus Henderson Group PLC | 2,935,442 | $77.09M | 0.0% | +2.1% | 5.500% |  |
| 2/18/2026 | Elmind Capital LP | 350,000 | $9.20M | 2.7% | N/A | 0.656% |  |
| 2/18/2026 | Eversept Partners LP | 278,564 | $7.32M | 0.4% | +2.1% | 0.522% |  |
| 2/18/2026 | Balyasny Asset Management L.P. | 818,326 | $21.51M | 0.0% | -3.3% | 1.533% |  |
| 2/18/2026 | Boone Capital Management LLC | 398,482 | $10.48M | 3.5% | N/A | 0.747% |  |
| 2/18/2026 | Boothbay Fund Management LLC | 221,177 | $5.82M | 0.1% | +18.5% | 0.414% |  |
| 2/18/2026 | BVF Inc. IL | 2,127,665 | $55.94M | 1.9% | -41.7% | 3.987% |  |
| 2/18/2026 | 5AM Venture Management LLC | 1,029,298 | $27.06M | 8.5% | +9.6% | 1.929% |  |
| 2/17/2026 | Logos Global Management LP | 210,000 | $5.52M | 0.3% | N/A | 0.393% |  |
| 2/17/2026 | Caligan Partners LP | 944,257 | $24.83M | 2.0% | +35.5% | 1.769% |  |
| 2/17/2026 | PDT Partners LLC | 42,284 | $1.11M | 0.1% | -2.4% | 0.079% |  |
| 2/17/2026 | AQR Capital Management LLC | 28,631 | $0.75M | 0.0% | +2.0% | 0.054% |  |
| 2/17/2026 | Farallon Capital Management LLC | 2,066,818 | $54.34M | 0.3% | +80.7% | 3.872% |  |
| 2/17/2026 | Price T Rowe Associates Inc. MD | 14,432 | $0.38M | 0.0% | +12.7% | 0.027% |  |
| 2/17/2026 | Public Employees Retirement System of Ohio | 18,542 | $0.49M | 0.0% | -25.7% | 0.035% |  |
| 2/17/2026 | State of Wisconsin Investment Board | 39,023 | $1.03M | 0.0% | +31.6% | 0.073% |  |
| 2/17/2026 | ExodusPoint Capital Management LP | 42,791 | $1.13M | 0.0% | N/A | 0.080% |  |
| 2/16/2026 | Squarepoint Ops LLC | 54,424 | $1.43M | 0.0% | +345.6% | 0.102% |  |
| 2/16/2026 | Barclays PLC | 76,309 | $2.01M | 0.0% | +33.6% | 0.143% |  |
| 2/13/2026 | Marshall Wace LLP | 711,891 | $18.72M | 0.0% | +18.3% | 1.334% |  |
| 2/13/2026 | The Manufacturers Life Insurance Company | 8,357 | $0.22M | 0.0% | N/A | 0.016% |  |
| 2/13/2026 | Kalehua Capital Management LLC | 74,465 | $1.96M | 1.8% | N/A | 0.140% |  |
| 2/13/2026 | Bank of Nova Scotia | 11,100 | $0.29M | 0.0% | N/A | 0.021% |  |
| 2/13/2026 | Jacobs Levy Equity Management Inc. | 129,753 | $3.41M | 0.0% | -48.4% | 0.243% |  |
| 2/13/2026 | Rafferty Asset Management LLC | 15,455 | $0.41M | 0.0% | N/A | 0.029% |  |
| 2/13/2026 | Charles Schwab Investment Management Inc. | 199,426 | $5.24M | 0.0% | -1.1% | 0.374% |  |
| 2/13/2026 | State Street Corp | 749,463 | $19.70M | 0.0% | +74.9% | 1.404% |  |
| 2/13/2026 | Caitong International Asset Management Co. Ltd | 1,941 | $51K | 0.1% | N/A | 0.004% |  |
| 2/13/2026 | Wells Fargo & Company MN | 29,049 | $0.76M | 0.0% | +57.3% | 0.054% |  |
| 2/12/2026 | MetLife Investment Management LLC | 15,356 | $0.40M | 0.0% | +5.0% | 0.029% |  |
| 2/12/2026 | Dimensional Fund Advisors LP | 95,640 | $2.51M | 0.0% | +141.0% | 0.179% |  |
| 2/12/2026 | Federated Hermes Inc. | 1,297 | $34K | 0.0% | -39.8% | 0.002% |  |
| 2/12/2026 | Alps Advisors Inc. | 43,827 | $1.15M | 0.0% | +77.4% | 0.082% |  |
| 2/12/2026 | Nuveen LLC | 47,349 | $1.25M | 0.0% | -41.1% | 0.089% |  |
| 2/11/2026 | Deutsche Bank AG | 16,377 | $0.43M | 0.0% | +5.8% | 0.031% |  |
| 2/11/2026 | Franklin Resources Inc. | 12,970 | $0.34M | 0.0% | N/A | 0.024% |  |
| 2/10/2026 | Goldman Sachs Group Inc. | 182,387 | $4.80M | 0.0% | +82.1% | 0.342% |  |
| 2/10/2026 | Intech Investment Management LLC | 9,801 | $0.26M | 0.0% | -14.0% | 0.018% |  |
| 2/9/2026 | Geode Capital Management LLC | 657,756 | $17.30M | 0.0% | +10.1% | 1.232% |  |
| 2/9/2026 | Fisher Asset Management LLC | 28,800 | $0.76M | 0.0% | N/A | 0.054% |  |
| 2/6/2026 | PSP Research LLC | 21,853 | $0.58M | 0.5% | N/A | 0.041% |  |
| 2/2/2026 | Chung Wu Investment Group LLC | 2,000 | $53K | 0.0% | N/A | 0.004% |  |
| 2/2/2026 | Oppenheimer & Co. Inc. | 84,726 | $2.23M | 0.0% | +3.0% | 0.159% |  |
| 1/29/2026 | China Universal Asset Management Co. Ltd. | 8,697 | $0.23M | 0.0% | -6.9% | 0.016% |  |
| 1/26/2026 | Mirae Asset Global Investments Co. Ltd. | 2,594 | $68K | 0.0% | +25.9% | 0.005% |  |
| 1/1/2026 | JPMorgan Chase & Co. | 74,229 | $1.04M | 0.0% | -27.9% | 0.139% |  |
| 1/1/2026 | Tudor Investment Corp ET AL | 10,761 | $0.15M | 0.0% | -59.0% | 0.020% |  |
| 12/9/2025 | Tudor Investment Corp ET AL | 10,761 | $0.15M | 0.0% | -59.0% | 0.020% |  |
| 11/17/2025 | Jacobs Levy Equity Management Inc. | 251,562 | $3.52M | 0.0% | -36.4% | 0.471% |  |
| 11/17/2025 | Vestal Point Capital LP | 2,425,000 | $33.93M | 1.5% | -8.7% | 4.544% |  |
| 11/17/2025 | Public Employees Retirement System of Ohio | 24,962 | $0.35M | 0.0% | +34.8% | 0.047% |  |
| 11/17/2025 | Millennium Management LLC | 144,016 | $2.02M | 0.0% | -64.7% | 0.270% |  |
| 11/17/2025 | MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 11,317 | $0.16M | 0.0% | -14.1% | 0.021% |  |
| 11/17/2025 | HighVista Strategies LLC | 65,812 | $0.92M | 0.2% | +163.6% | 0.123% |  |
| 11/17/2025 | Brevan Howard Capital Management LP | 31,101 | $0.44M | 0.0% | -15.0% | 0.058% |  |
| 11/17/2025 | Commodore Capital LP | 3,375,000 | $47.22M | 2.3% | +8.9% | 6.324% |  |
| 11/17/2025 | Bank of America Corp DE | 134,319 | $1.88M | 0.0% | -64.0% | 0.252% |  |
| 11/17/2025 | Boothbay Fund Management LLC | 186,670 | $2.61M | 0.0% | N/A | 0.350% |  |
| 11/17/2025 | Alliancebernstein L.P. | 33,260 | $0.47M | 0.0% | -6.7% | 0.062% |  |
| 11/17/2025 | Ameriprise Financial Inc. | 87,107 | $1.22M | 0.0% | +8.1% | 0.163% |  |
| 11/14/2025 | Raymond James Financial Inc. | 126,374 | $1.77M | 0.0% | +100.0% | 0.237% |  |
| 11/14/2025 | Caligan Partners LP | 696,825 | $9.75M | 1.3% | +266.8% | 1.306% |  |
| 11/14/2025 | Balyasny Asset Management L.P. | 846,585 | $11.84M | 0.0% | +45.1% | 1.586% |  |
| 11/14/2025 | Two Sigma Investments LP | 199,438 | $2.79M | 0.0% | +88.5% | 0.374% |  |
| 11/14/2025 | Squarepoint Ops LLC | 12,214 | $0.17M | 0.0% | -61.1% | 0.023% |  |
| 11/13/2025 | Marshall Wace LLP | 602,015 | $8.42M | 0.0% | +40.6% | 1.128% |  |
| 11/13/2025 | UBS Group AG | 59,144 | $0.83M | 0.0% | +27.8% | 0.111% |  |
| 11/13/2025 | BNP Paribas Financial Markets | 128,881 | $1.80M | 0.0% | +31.9% | 0.241% |  |
| 11/13/2025 | Russell Investments Group Ltd. | 12,741 | $0.18M | 0.0% | +27.7% | 0.024% |  |
| 11/12/2025 | Barclays PLC | 57,126 | $0.80M | 0.0% | -7.2% | 0.107% |  |
| 11/12/2025 | Dimensional Fund Advisors LP | 39,679 | $0.56M | 0.0% | -4.8% | 0.074% |  |
| 11/12/2025 | Victory Capital Management Inc. | 18,790 | $0.26M | 0.0% | -57.5% | 0.035% |  |
| 11/12/2025 | Intech Investment Management LLC | 11,402 | $0.16M | 0.0% | -42.8% | 0.021% |  |
| 11/10/2025 | China Universal Asset Management Co. Ltd. | 9,342 | $0.13M | 0.0% | -12.5% | 0.018% |  |
| 11/7/2025 | Vanguard Group Inc. | 1,520,185 | $21.27M | 0.0% | +8.5% | 2.852% |  |
| 11/7/2025 | JPMorgan Chase & Co. | 74,229 | $1.04M | 0.0% | -27.9% | 0.139% |  |
| 11/6/2025 | Oppenheimer & Co. Inc. | 82,238 | $1.15M | 0.0% | +11.1% | 0.154% |  |
| 11/5/2025 | Alps Advisors Inc. | 24,700 | $0.35M | 0.0% | -14.0% | 0.046% |  |
| 11/3/2025 | AlphaQuest LLC | 30,060 | $0.42M | 0.0% | -58.9% | 0.056% |  |
| 11/3/2025 | Federated Hermes Inc. | 2,155 | $30K | 0.0% | +586.3% | 0.004% |  |
| 10/23/2025 | SG Americas Securities LLC | 9,542 | $0.13M | 0.0% | N/A | 0.018% |  |
| 8/15/2025 | Vestal Point Capital LP | 2,655,000 | $25.41M | 1.3% | -7.8% | 5.001% |  |
| 8/15/2025 | BNP Paribas Financial Markets | 97,736 | $0.94M | 0.0% | +41.7% | 0.184% |  |
| 8/15/2025 | Brevan Howard Capital Management LP | 36,594 | $0.35M | 0.0% | -21.1% | 0.069% |  |
| 8/15/2025 | Balyasny Asset Management L.P. | 583,386 | $5.58M | 0.0% | +139.8% | 1.099% |  |
| 8/15/2025 | Bank of America Corp DE | 372,967 | $3.57M | 0.0% | +346.6% | 0.703% |  |
| 8/15/2025 | Ameriprise Financial Inc. | 80,602 | $0.77M | 0.0% | N/A | 0.152% |  |
| 8/14/2025 | PDT Partners LLC | 43,310 | $0.41M | 0.0% | N/A | 0.082% |  |
| 8/14/2025 | Orbimed Advisors LLC | 804,603 | $7.70M | 0.2% | -54.1% | 1.516% |  |
| 8/14/2025 | Commodore Capital LP | 3,100,000 | $29.67M | 2.1% | +226.3% | 5.839% |  |
| 8/14/2025 | Jane Street Group LLC | 58,168 | $0.56M | 0.0% | +67.1% | 0.110% |  |