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TYRA Insider Trading

Insider Ownership Percentage: 15.20%
Insider Buying (Last 12 Months): $0.00
Insider Selling (Last 12 Months): $5,972,313.26

Tyra Biosciences Insider Trading History Chart

This chart shows the insider buying and selling history at Tyra Biosciences by year and by quarter.

Skip ChartChart Data in Insider Trading History Table

Tyra Biosciences Share Price & Price History

Current Price: $22.11
Price Change: ▲ Price Increase of +0.41 (1.89%)
As of 12/4/2025 05:00 PM ET

This chart shows the closing price history over time for TYRA up to the past year.

Skip Chart and Table DataPrice Data in Insider Trading History Table
Days: 30 | 90 | 365

Tyra Biosciences Insider Trading History

Transaction DateInsider NameTitleBuy/SellNumber of SharesAverage Share PriceTotal TransactionShares Held After TransactionDetails
11/21/2025Robert J MoreDirectorSell246,871$20.25$4,999,137.753,833,425View SEC Filing Icon  
6/18/2025Gilla KaplanDirectorSell9,568$9.78$93,575.0428,231View SEC Filing Icon  
6/17/2025Gilla KaplanDirectorSell10$10.35$103.5037,799View SEC Filing Icon  
6/16/2025Gilla KaplanDirectorSell6,814$10.38$70,729.3237,809View SEC Filing Icon  
6/13/2025Gilla KaplanDirectorSell15,000$10.31$154,650.0044,623View SEC Filing Icon  
6/12/2025Gilla KaplanDirectorSell30,000$10.31$309,300.0059,623View SEC Filing Icon  
2/5/2025Nina S KjellsonDirectorSell5,401$13.76$74,317.76443,885View SEC Filing Icon  
1/23/2025Nina S KjellsonDirectorSell4,825$16.26$78,454.503,702,595View SEC Filing Icon  
1/21/2025Nina S KjellsonDirectorSell3,993$16.36$65,325.483,707,420View SEC Filing Icon  
1/16/2025Nina S KjellsonDirectorSell7,779$16.29$126,719.91447,857View SEC Filing Icon  
11/4/2024Nina S KjellsonDirectorSell1,076$17.01$18,302.76458,390View SEC Filing Icon  
11/1/2024Nina S KjellsonDirectorSell27,493$16.56$455,284.08458,506View SEC Filing Icon  
10/30/2024Alan FuhrmanCFOBuy9,500$16.00$152,000.0012,849View SEC Filing Icon  
10/30/2024Nina S KjellsonDirectorSell11,078$16.17$179,131.26472,207View SEC Filing Icon  
10/21/2024Todd HarrisCEOSell19,084$27.90$532,443.601,355,927View SEC Filing Icon  
10/17/2024Todd HarrisCEOSell15,394$25.85$397,934.901,418,647View SEC Filing Icon  
10/15/2024Todd HarrisCEOSell10,035$24.31$243,950.851,467,338View SEC Filing Icon  
9/30/2024Todd HarrisCEOSell500$24.00$12,000.001,477,373View SEC Filing Icon  
9/25/2024Todd HarrisCEOSell600$24.01$14,406.001,477,873View SEC Filing Icon  
9/23/2024Todd HarrisCEOSell10,092$24.13$243,519.961,479,528View SEC Filing Icon  
9/19/2024Todd HarrisCEOSell5,698$24.31$138,518.381,496,729View SEC Filing Icon  
6/10/2024Daniel BensenCOOSell3,502$20.00$70,040.00427,981View SEC Filing Icon  
6/7/2024Daniel BensenCOOSell200$20.00$4,000.00431,483View SEC Filing Icon  
3/11/2024Daniel BensenCOOSell200$20.00$4,000.00431,683View SEC Filing Icon  
3/6/2024Daniel BensenCOOSell1,733$20.09$34,815.97431,951View SEC Filing Icon  
2/29/2024Daniel BensenCOOSell2,050$20.00$41,000.00442,836View SEC Filing Icon  
2/27/2024Daniel BensenCOOSell745$20.00$14,900.00450,735View SEC Filing Icon  
2/12/2024Daniel BensenCOOSell1,501$20.00$30,020.00451,480View SEC Filing Icon  
2/7/2024Daniel BensenCOOSell9,587$18.09$173,428.83452,981View SEC Filing Icon  
7/21/2023Daniel BensenCOOSell3,900$16.01$62,439.00527,981View SEC Filing Icon  
7/19/2023Daniel BensenCOOSell207$16.07$3,326.49527,981View SEC Filing Icon  
7/17/2023Daniel BensenCOOSell1,900$16.03$30,457.00527,981View SEC Filing Icon  
7/13/2023Daniel BensenCOOSell500$16.13$8,065.00527,981View SEC Filing Icon  
7/11/2023Daniel BensenCOOSell500$16.02$8,010.00527,981View SEC Filing Icon  
7/3/2023Daniel BensenCOOSell4,265$16.37$69,818.05527,981View SEC Filing Icon  
6/30/2023Daniel BensenCOOSell18,819$16.97$319,358.43527,981View SEC Filing Icon  
6/27/2023Daniel BensenCOOSell16,028$16.91$271,033.48527,981View SEC Filing Icon  
6/22/2023Todd HarrisCEOSell3,478$17.04$59,265.121,621,988View SEC Filing Icon  
6/20/2023Todd HarrisCEOSell1,300$16.53$21,489.001,645,222View SEC Filing Icon  
6/15/2023Todd HarrisCEOSell12,773$16.13$206,028.491,701,276View SEC Filing Icon  
6/14/2023Daniel BensenCOOSell120$16.45$1,974.00527,981View SEC Filing Icon  
6/13/2023Todd HarrisCEOSell7,927$16.00$126,832.001,701,276View SEC Filing Icon  
4/3/2023Daniel BensenCOOSell2,000$16.16$32,320.00527,981View SEC Filing Icon  
3/31/2023Daniel BensenCOOSell400$16.00$6,400.00527,981View SEC Filing Icon  
3/30/2023Todd HarrisCEOSell2,407$16.02$38,560.141,701,276View SEC Filing Icon  
3/29/2023Daniel BensenCOOSell2,187$16.21$35,451.27527,981View SEC Filing Icon  
3/28/2023Todd HarrisCEOSell2,779$16.00$44,464.001,701,276View SEC Filing Icon  
3/27/2023Daniel BensenCOOSell8,048$16.00$128,768.00527,981View SEC Filing Icon  
3/24/2023Todd HarrisCEOSell170$16.00$2,720.001,701,276View SEC Filing Icon  
3/22/2023Daniel BensenCOOSell3,800$16.00$60,800.00527,981View SEC Filing Icon  
3/22/2023Todd HarrisCEOSell4,043$16.00$64,688.001,701,276View SEC Filing Icon  
2/9/2023Mva Investors, LlcMajor ShareholderSell200,000$13.10$2,620,000.0088,095View SEC Filing Icon  
See Full Table

SEC Filings (Institutional Ownership Changes) for Tyra Biosciences (NASDAQ:TYRA)

84.14% of Tyra Biosciences stock is owned by institutions. Institutional ownership can be a sign of analyst confidence in the fundamentals of the stock.

Institutional Buying and Selling by Quarter

This chart shows the instiutional buying and selling at TYRA by year and by quarter.

Skip Institutional Buying and Selling Chart and Table DataRead Chart Data in Institutional Trading History Table

Tyra Biosciences Institutional Trading History

Reporting DateHedge FundShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
11/17/2025Jacobs Levy Equity Management Inc.251,562$3.52M0.0%-36.4%0.471%Search for SEC Filing on Google Icon
11/17/2025Vestal Point Capital LP2,425,000$33.93M1.5%-8.7%4.544%Search for SEC Filing on Google Icon
11/17/2025Public Employees Retirement System of Ohio24,962$0.35M0.0%+34.8%0.047%Search for SEC Filing on Google Icon
11/17/2025Millennium Management LLC144,016$2.02M0.0%-64.7%0.270%Search for SEC Filing on Google Icon
11/17/2025MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.11,317$0.16M0.0%-14.1%0.021%Search for SEC Filing on Google Icon
11/17/2025HighVista Strategies LLC65,812$0.92M0.2%+163.6%0.123%Search for SEC Filing on Google Icon
11/17/2025Brevan Howard Capital Management LP31,101$0.44M0.0%-15.0%0.058%Search for SEC Filing on Google Icon
11/17/2025Commodore Capital LP3,375,000$47.22M2.3%+8.9%6.324%Search for SEC Filing on Google Icon
11/17/2025Bank of America Corp DE134,319$1.88M0.0%-64.0%0.252%Search for SEC Filing on Google Icon
11/17/2025Boothbay Fund Management LLC186,670$2.61M0.0%N/A0.350%Search for SEC Filing on Google Icon
11/17/2025Alliancebernstein L.P.33,260$0.47M0.0%-6.7%0.062%Search for SEC Filing on Google Icon
11/17/2025Ameriprise Financial Inc.87,107$1.22M0.0%+8.1%0.163%Search for SEC Filing on Google Icon
11/14/2025Raymond James Financial Inc.126,374$1.77M0.0%+100.0%0.237%Search for SEC Filing on Google Icon
11/14/2025Caligan Partners LP696,825$9.75M1.3%+266.8%1.306%Search for SEC Filing on Google Icon
11/14/2025Balyasny Asset Management L.P.846,585$11.84M0.0%+45.1%1.586%Search for SEC Filing on Google Icon
11/14/2025Two Sigma Investments LP199,438$2.79M0.0%+88.5%0.374%Search for SEC Filing on Google Icon
11/14/2025Squarepoint Ops LLC12,214$0.17M0.0%-61.1%0.023%Search for SEC Filing on Google Icon
11/13/2025Marshall Wace LLP602,015$8.42M0.0%+40.6%1.128%Search for SEC Filing on Google Icon
11/13/2025UBS Group AG59,144$0.83M0.0%+27.8%0.111%Search for SEC Filing on Google Icon
11/13/2025BNP Paribas Financial Markets128,881$1.80M0.0%+31.9%0.241%Search for SEC Filing on Google Icon
11/13/2025Russell Investments Group Ltd.12,741$0.18M0.0%+27.7%0.024%Search for SEC Filing on Google Icon
11/12/2025Barclays PLC57,126$0.80M0.0%-7.2%0.107%Search for SEC Filing on Google Icon
11/12/2025Dimensional Fund Advisors LP39,679$0.56M0.0%-4.8%0.074%Search for SEC Filing on Google Icon
11/12/2025Victory Capital Management Inc.18,790$0.26M0.0%-57.5%0.035%Search for SEC Filing on Google Icon
11/12/2025Intech Investment Management LLC11,402$0.16M0.0%-42.8%0.021%Search for SEC Filing on Google Icon
11/10/2025China Universal Asset Management Co. Ltd.9,342$0.13M0.0%-12.5%0.018%Search for SEC Filing on Google Icon
11/7/2025Vanguard Group Inc.1,520,185$21.27M0.0%+8.5%2.852%Search for SEC Filing on Google Icon
11/7/2025JPMorgan Chase & Co.74,229$1.04M0.0%-27.9%0.139%Search for SEC Filing on Google Icon
11/6/2025Oppenheimer & Co. Inc.82,238$1.15M0.0%+11.1%0.154%Search for SEC Filing on Google Icon
11/5/2025Alps Advisors Inc.24,700$0.35M0.0%-14.0%0.046%Search for SEC Filing on Google Icon
11/3/2025AlphaQuest LLC30,060$0.42M0.0%-58.9%0.056%Search for SEC Filing on Google Icon
11/3/2025Federated Hermes Inc.2,155$30K0.0%+586.3%0.004%Search for SEC Filing on Google Icon
10/23/2025SG Americas Securities LLC9,542$0.13M0.0%N/A0.018%Search for SEC Filing on Google Icon
8/15/2025Vestal Point Capital LP2,655,000$25.41M1.3%-7.8%5.001%Search for SEC Filing on Google Icon
8/15/2025BNP Paribas Financial Markets97,736$0.94M0.0%+41.7%0.184%Search for SEC Filing on Google Icon
8/15/2025Brevan Howard Capital Management LP36,594$0.35M0.0%-21.1%0.069%Search for SEC Filing on Google Icon
8/15/2025Balyasny Asset Management L.P.583,386$5.58M0.0%+139.8%1.099%Search for SEC Filing on Google Icon
8/15/2025Bank of America Corp DE372,967$3.57M0.0%+346.6%0.703%Search for SEC Filing on Google Icon
8/15/2025Ameriprise Financial Inc.80,602$0.77M0.0%N/A0.152%Search for SEC Filing on Google Icon
8/14/2025PDT Partners LLC43,310$0.41M0.0%N/A0.082%Search for SEC Filing on Google Icon
8/14/2025Orbimed Advisors LLC804,603$7.70M0.2%-54.1%1.516%Search for SEC Filing on Google Icon
8/14/2025Commodore Capital LP3,100,000$29.67M2.1%+226.3%5.839%Search for SEC Filing on Google Icon
8/14/2025Jane Street Group LLC58,168$0.56M0.0%+67.1%0.110%Search for SEC Filing on Google Icon
8/14/2025Raymond James Financial Inc.63,187$0.61M0.0%+16.3%0.119%Search for SEC Filing on Google Icon
8/14/2025MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.13,182$0.13M0.0%+14.5%0.025%Search for SEC Filing on Google Icon
8/14/2025HighVista Strategies LLC24,962$0.24M0.1%+4.3%0.047%Search for SEC Filing on Google Icon
8/13/2025Jump Financial LLC71,119$0.68M0.0%+154.5%0.134%Search for SEC Filing on Google Icon
8/13/2025Marshall Wace LLP428,108$4.10M0.0%+12.5%0.806%Search for SEC Filing on Google Icon
8/13/2025Walleye Capital LLC370,408$3.55M0.0%+163.2%0.698%Search for SEC Filing on Google Icon
8/13/2025Sio Capital Management LLC810,274$7.75M3.0%+94.5%1.526%Search for SEC Filing on Google Icon
8/13/2025Virtus Investment Advisers LLC9,103$87K0.0%-15.9%0.017%Search for SEC Filing on Google Icon
8/12/2025XTX Topco Ltd34,601$0.33M0.0%N/A0.065%Search for SEC Filing on Google Icon
8/12/2025American Century Companies Inc.28,854$0.28M0.0%+23.1%0.054%Search for SEC Filing on Google Icon
8/12/2025Rhumbline Advisers40,685$0.39M0.0%+44.9%0.077%Search for SEC Filing on Google Icon
8/12/2025JPMorgan Chase & Co.102,917$0.99M0.0%+20.4%0.194%Search for SEC Filing on Google Icon
8/12/2025Dynamic Technology Lab Private Ltd34,115$0.33M0.0%N/A0.064%Search for SEC Filing on Google Icon
8/8/2025Intech Investment Management LLC19,919$0.19M0.0%+46.5%0.038%Search for SEC Filing on Google Icon
8/8/2025Geode Capital Management LLC567,126$5.43M0.0%+9.8%1.068%Search for SEC Filing on Google Icon
8/5/2025Corton Capital Inc.24,346$0.23M0.3%N/A0.046%Search for SEC Filing on Google Icon
7/31/2025AlphaQuest LLC73,073$0.70M0.1%+146.7%0.138%Search for SEC Filing on Google Icon
7/17/2025Canaan Partners XI LLC3,608,109$34.53M20.1%-12.9%6.796%Search for SEC Filing on Google Icon
7/15/2025Public Employees Retirement System of Ohio18,512$0.18M0.0%N/A0.035%Search for SEC Filing on Google Icon
6/27/2025Goldman Sachs Group Inc.78,006$0.73M0.0%+21.7%0.147%Search for SEC Filing on Google Icon
5/29/2025Rhumbline Advisers28,081$0.26M0.0%+7.2%0.053%Search for SEC Filing on Google Icon
5/19/2025Jane Street Group LLC34,813$0.32M0.0%N/A0.066%Search for SEC Filing on Google Icon
5/16/2025Woodline Partners LP100,108$0.93M0.0%N/A0.189%Search for SEC Filing on Google Icon
5/16/2025Goldman Sachs Group Inc.78,006$0.73M0.0%+21.7%0.147%Search for SEC Filing on Google Icon
5/16/2025Polar Asset Management Partners Inc.141,241$1.31M0.0%+27.1%0.266%Search for SEC Filing on Google Icon
5/16/2025Millennium Management LLC404,165$3.76M0.0%+28.2%0.761%Search for SEC Filing on Google Icon
5/16/2025Jacobs Levy Equity Management Inc.301,801$2.81M0.0%+23.6%0.568%Search for SEC Filing on Google Icon
5/16/2025Ally Bridge Group NY LLC107,244$1M0.9%-38.7%0.202%Search for SEC Filing on Google Icon
5/15/2025Vestal Point Capital LP2,879,829$26.78M1.9%+190.9%5.424%Search for SEC Filing on Google Icon
5/15/2025Cubist Systematic Strategies LLC91,844$0.85M0.0%-16.3%0.173%Search for SEC Filing on Google Icon
5/14/2025Walleye Capital LLC140,742$1.31M0.0%+123.5%0.265%Search for SEC Filing on Google Icon
5/14/2025Jump Financial LLC27,949$0.26M0.0%+84.4%0.053%Search for SEC Filing on Google Icon
5/14/2025AlphaQuest LLC29,622$0.28M0.0%+489.7%0.056%Search for SEC Filing on Google Icon
5/14/2025EntryPoint Capital LLC14,892$0.14M0.1%-18.2%0.028%Search for SEC Filing on Google Icon
5/14/2025Wellington Management Group LLP104,087$0.97M0.0%+9.7%0.196%Search for SEC Filing on Google Icon
5/13/2025American Century Companies Inc.23,431$0.22M0.0%+5.8%0.044%Search for SEC Filing on Google Icon
5/12/2025Nuveen LLC49,998$0.47M0.0%N/A0.094%Search for SEC Filing on Google Icon
5/12/2025Swiss National Bank29,400$0.27M0.0%+42.0%0.055%Search for SEC Filing on Google Icon
5/9/2025Deutsche Bank AG16,979$0.16M0.0%-10.2%0.032%Search for SEC Filing on Google Icon
5/9/2025Charles Schwab Investment Management Inc.164,108$1.53M0.0%-3.8%0.309%Search for SEC Filing on Google Icon
5/8/2025US Bancorp DE5,435$51K0.0%+50.5%0.010%Search for SEC Filing on Google Icon
5/7/2025Zurcher Kantonalbank Zurich Cantonalbank9,047$84K0.0%N/A0.017%Search for SEC Filing on Google Icon
4/29/2025Bank of New York Mellon Corp41,083$0.38M0.0%-8.7%0.077%Search for SEC Filing on Google Icon
4/17/2025Exchange Traded Concepts LLC11,861$0.11M0.0%+42.7%0.022%Search for SEC Filing on Google Icon
4/9/2025Canaan Partners XI LLC4,144,590$38.55M58.1%-0.8%7.807%Search for SEC Filing on Google Icon
4/8/2025Rhumbline Advisers28,081$0.26M0.0%+7.2%0.053%Search for SEC Filing on Google Icon
3/24/2025Wellington Management Group LLP94,859$1.32M0.0%+4.4%0.187%Search for SEC Filing on Google Icon
3/18/2025California State Teachers Retirement System10,570$0.15M0.0%-18.3%0.021%Search for SEC Filing on Google Icon
2/25/2025Polar Asset Management Partners Inc.111,107$1.54M0.0%+26.1%0.220%Search for SEC Filing on Google Icon
2/17/2025UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC35,635$0.50M0.0%+41.4%0.070%Search for SEC Filing on Google Icon
2/17/2025Vestal Point Capital LP990,000$13.76M0.8%N/A1.956%Search for SEC Filing on Google Icon
2/17/2025Squarepoint Ops LLC18,216$0.25M0.0%N/A0.036%Search for SEC Filing on Google Icon
2/17/2025Two Sigma Advisers LP12,300$0.17M0.0%N/A0.024%Search for SEC Filing on Google Icon
2/17/2025Two Sigma Investments LP46,269$0.64M0.0%+18.1%0.091%Search for SEC Filing on Google Icon
2/17/2025Point72 Asset Management L.P.12,783$0.18M0.0%N/A0.025%Search for SEC Filing on Google Icon
2/17/2025Polar Asset Management Partners Inc.111,107$1.54M0.0%+26.1%0.220%Search for SEC Filing on Google Icon
2/17/2025Orbimed Advisors LLC1,470,086$20.43M0.4%+91.3%2.905%Search for SEC Filing on Google Icon
Data available starting January 2016

See Full Table
Tyra Biosciences logo
Tyra Biosciences, Inc., a clinical-stage biotechnology company, develops precision medicines for fibroblast growth factor receptor (FGFR) biology in the United States. The company offers SNÅP, a precision medicine platform that enables drug design through iterative molecular snapshots to predict genetic alterations for developing therapies targeting oncology and genetically defined conditions. Its lead product candidate is TYRA-300, which is in Phase 1/2 clinical trials for the treatment of patients with metastatic urothelial carcinoma and other solid tumors. The company is also developing TYRA-300 for skeletal conditions, including achondroplasia, hypochondroplasia, thanatophoric dysplasia, and other FGFR3-driven genetic syndromes; TYRA-200, a candidate in Phase 1 clinical trial for bile duct and solid tumors; and TYRA-430 for the treatment of hepatocellular carcinoma. The company was incorporated in 2018 and is headquartered in Carlsbad, California.
Read More on Tyra Biosciences

Today's Range

Now: $22.11
Low: $21.43
High: $22.13

50 Day Range

MA: $16.14
Low: $12.97
High: $22.51

52 Week Range

Now: $22.11
Low: $6.42
High: $22.83

Volume

916,903 shs

Average Volume

466,587 shs

Market Capitalization

$1.18 billion

P/E Ratio

N/A

Dividend Yield

N/A

Beta

1.09

Who are the company insiders with the largest holdings of Tyra Biosciences?

Tyra Biosciences' top insider investors include:
  1. Robert J More (Director)
  2. Nina S Kjellson (Director)
  3. Todd Harris (CEO)
  4. Daniel Bensen (COO)
  5. Gilla Kaplan (Director)
  6. Alan Fuhrman (CFO)
Learn More about top insider investors at Tyra Biosciences.

Who are the major institutional investors of Tyra Biosciences?

Tyra Biosciences' top institutional investors include:
  1. Commodore Capital LP — 6.32%
  2. Vestal Point Capital LP — 4.54%
  3. Vanguard Group Inc. — 2.85%
  4. Balyasny Asset Management L.P. — 1.59%
  5. Caligan Partners LP — 1.31%
  6. Marshall Wace LLP — 1.13%
Learn More about top institutional investors of Tyra Biosciences stock.

Which institutional investors are selling Tyra Biosciences stock?

Within the last quarter, TYRA stock was sold by these institutional investors:
  1. Millennium Management LLC
  2. Bank of America Corp DE
  3. Vestal Point Capital LP
  4. Jacobs Levy Equity Management Inc.
  5. AlphaQuest LLC
  6. JPMorgan Chase & Co.
  7. Victory Capital Management Inc.
  8. Squarepoint Ops LLC
In the last year, company insiders that have sold Tyra Biosciences company stock include:
  1. Robert J More (Director)
  2. Nina S Kjellson (Director)
  3. Todd Harris (CEO)
Learn More investors selling Tyra Biosciences stock.

Which institutional investors are buying Tyra Biosciences stock?

In the last quarter, TYRA stock was purchased by institutional investors including:
  1. Caligan Partners LP
  2. Commodore Capital LP
  3. Balyasny Asset Management L.P.
  4. Boothbay Fund Management LLC
  5. Marshall Wace LLP
  6. Vanguard Group Inc.
  7. Two Sigma Investments LP
  8. Raymond James Financial Inc.