| 9/9/2026 | Opaleye Management Inc. | 1,439,996 | $52.99M | 4.8% | +0.7% | 2.946% |  |
| 9/9/2026 | Tidal Investments LLC | 101,837 | $3.75M | 0.0% | -1.1% | 0.208% |  |
| 9/9/2026 | Engineers Gate Manager LP | 16,378 | $0.60M | 0.0% | N/A | 0.034% |  |
| 9/9/2026 | Integrated Wealth Concepts LLC | 11,741 | $0.43M | 0.0% | -7.1% | 0.024% |  |
| 9/9/2026 | Squarepoint Ops LLC | 11,699 | $0.43M | 0.0% | N/A | 0.024% |  |
| 8/19/2026 | UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 874 | $32K | 0.0% | -98.2% | 0.002% |  |
| 8/19/2026 | Wellington Management Group LLP | 115,362 | $4.25M | 0.0% | +15.1% | 0.236% |  |
| 8/18/2026 | Palo Alto Investors LP | 24,500 | $0.90M | 0.0% | N/A | 0.050% |  |
| 8/18/2026 | Coastal Bridge Advisors LLC | 37,000 | $1.36M | 0.1% | N/A | 0.076% |  |
| 8/18/2026 | Jefferies Financial Group Inc. | 2,199,652 | $80.95M | 0.5% | N/A | 4.500% |  |
| 8/17/2026 | Bank of America Corp DE | 475,702 | $17.51M | 0.0% | N/A | 0.973% |  |
| 8/15/2026 | Jupiter Topco LLC | 19,100 | $0.70M | 0.0% | N/A | 0.039% |  |
| 8/15/2026 | Elmind Capital LP | 120,000 | $4.42M | 0.0% | N/A | 0.245% |  |
| 8/14/2026 | ADAR1 Capital Management LLC | 252,395 | $9.29M | 0.4% | N/A | 0.516% |  |
| 8/14/2026 | Parkman Healthcare Partners LLC | 174,064 | $6.41M | 0.7% | N/A | 0.356% |  |
| 8/14/2026 | Legal & General Group Plc | 35,830 | $1.32M | 0.0% | N/A | 0.073% |  |
| 8/14/2026 | The Manufacturers Life Insurance Company | 11,197 | $0.41M | 0.0% | N/A | 0.023% |  |
| 8/14/2026 | Partners Capital Investment Group LLP | 15,384 | $0.57M | 0.0% | N/A | 0.031% |  |
| 8/14/2026 | Algert Global LLC | 32,350 | $1.19M | 0.0% | +70.4% | 0.066% |  |
| 8/12/2026 | Quantbot Technologies LP | 2,133 | $78K | 0.0% | N/A | 0.004% |  |
| 8/8/2026 | Main Street Financial Solutions LLC | 8,190 | $0.30M | 0.0% | -61.0% | 0.017% |  |
| 8/7/2026 | BlackRock Inc. | 3,201,461 | $117.81M | 0.0% | N/A | 6.571% |  |
| 8/7/2026 | Deutsche Bank AG | 51,550 | $1.90M | 0.0% | N/A | 0.106% |  |
| 8/7/2026 | Rice Hall James & Associates LLC | 300,650 | $11.06M | 0.5% | N/A | 0.617% |  |
| 8/7/2026 | Persistent Asset Partners Ltd | 1,790 | $66K | 0.0% | N/A | 0.004% |  |
| 8/6/2026 | Bank of New York Mellon Corp | 113,028 | $4.16M | 0.0% | N/A | 0.232% |  |
| 7/9/2026 | Hennion & Walsh Asset Management Inc. | 276,696 | $10.18M | 0.3% | +50.8% | 0.568% |  |
| 5/26/2026 | Glenmede Trust Co. NA | 10,517 | $0.19M | 0.0% | N/A | 0.022% |  |
| 5/19/2026 | Bank of America Corp DE | 126,783 | $2.28M | 0.0% | -1.4% | 0.260% |  |
| 5/19/2026 | Janus Henderson Group PLC | 19,100 | $0.34M | 0.0% | N/A | 0.039% |  |
| 5/19/2026 | Ally Bridge Group NY LLC | 202,124 | $3.63M | 2.9% | N/A | 0.415% |  |
| 5/18/2026 | ADAR1 Capital Management LLC | 395,459 | $7.11M | 0.4% | +139.1% | 0.812% |  |
| 5/18/2026 | California State Teachers Retirement System | 38,750 | $0.70M | 0.0% | +1,605.5% | 0.080% |  |
| 5/18/2026 | Elmind Capital LP | 220,000 | $3.96M | 1.1% | +120.0% | 0.452% |  |
| 5/16/2026 | The Manufacturers Life Insurance Company | 10,909 | $0.20M | 0.0% | -80.4% | 0.022% |  |
| 5/16/2026 | Quantinno Capital Management LP | 20,176 | $0.36M | 0.0% | -14.2% | 0.041% |  |
| 5/15/2026 | Rice Hall James & Associates LLC | 285,834 | $5.14M | 0.3% | +1.4% | 0.587% |  |
| 5/14/2026 | Healthcare of Ontario Pension Plan Trust Fund | 387,074 | $6.96M | 0.0% | -65.6% | 0.794% |  |
| 5/13/2026 | Cetera Investment Advisers | 29,096 | $0.52M | 0.0% | -3.3% | 0.060% |  |
| 5/7/2026 | Swiss National Bank | 77,800 | $1.40M | 0.0% | N/A | 0.160% |  |
| 4/29/2026 | Meitav Investment House Ltd. | 22,223 | $0.40M | 0.0% | -37.4% | 0.046% |  |
| 4/16/2026 | SG Americas Securities LLC | 1,657,846 | $29.81M | 0.0% | +20.3% | 3.406% |  |
| 3/20/2026 | Hsbc Holdings PLC | 10,316 | $0.24M | 0.0% | -25.7% | 0.021% |  |
| 2/19/2026 | Invesco Ltd. | 27,066 | $0.63M | 0.0% | +21.1% | 0.058% |  |
| 2/18/2026 | XTX Topco Ltd | 22,491 | $0.53M | 0.0% | -23.2% | 0.048% |  |
| 2/18/2026 | Voloridge Investment Management LLC | 435,490 | $10.20M | 0.0% | -36.7% | 0.930% |  |
| 2/18/2026 | Susquehanna Portfolio Strategies LLC | 27,380 | $0.64M | 0.0% | N/A | 0.058% |  |
| 2/18/2026 | Tang Capital Management LLC | 350,000 | $8.20M | 0.4% | -65.0% | 0.748% |  |
| 2/18/2026 | Superstring Capital Management LP | 718,354 | $16.82M | 9.0% | +717.1% | 1.535% |  |
| 2/18/2026 | Orbimed Advisors LLC | 875,487 | $20.50M | 0.4% | +27.1% | 1.870% |  |
| 2/18/2026 | Opaleye Management Inc. | 268,423 | $6.29M | 0.8% | N/A | 0.573% |  |
| 2/18/2026 | Millennium Management LLC | 618,952 | $14.50M | 0.0% | -59.1% | 1.322% |  |
| 2/18/2026 | Main Street Financial Solutions LLC | 20,990 | $0.49M | 0.0% | -34.8% | 0.045% |  |
| 2/18/2026 | Elmind Capital LP | 100,000 | $2.34M | 0.7% | N/A | 0.214% |  |
| 2/18/2026 | Cinctive Capital Management LP | 16,991 | $0.40M | 0.0% | N/A | 0.036% |  |
| 2/17/2026 | AQR Capital Management LLC | 153,413 | $3.59M | 0.0% | -24.9% | 0.328% |  |
| 2/17/2026 | Cetera Investment Advisers | 30,096 | $0.71M | 0.0% | -6.2% | 0.064% |  |
| 2/17/2026 | MPM Bioimpact LLC | 941,378 | $22.05M | 2.5% | +597.3% | 2.011% |  |
| 2/17/2026 | Paradigm Biocapital Advisors LP | 4,473,648 | $104.77M | 2.7% | +6.1% | 9.557% |  |
| 2/17/2026 | Jump Financial LLC | 17,900 | $0.42M | 0.0% | -82.8% | 0.038% |  |
| 2/17/2026 | Price T Rowe Associates Inc. MD | 616,606 | $14.44M | 0.0% | +72.9% | 1.317% |  |
| 2/17/2026 | Diadema Partners LP | 21,810 | $0.51M | 0.1% | -75.8% | 0.047% |  |
| 2/17/2026 | Russell Investments Group Ltd. | 47,257 | $1.11M | 0.0% | +1,323.0% | 0.101% |  |
| 2/17/2026 | Atom Investors LP | 234,423 | $5.49M | 0.4% | -19.7% | 0.501% |  |
| 2/17/2026 | ExodusPoint Capital Management LP | 35,393 | $0.83M | 0.0% | +113.9% | 0.076% |  |
| 2/17/2026 | Royal Bank of Canada | 8,391 | $0.20M | 0.0% | -81.5% | 0.018% |  |
| 2/17/2026 | Persistent Asset Partners Ltd | 12,806 | $0.30M | 0.1% | -38.2% | 0.027% |  |
| 2/17/2026 | Rice Hall James & Associates LLC | 281,876 | $6.60M | 0.4% | +8.8% | 0.602% |  |
| 2/16/2026 | Squarepoint Ops LLC | 22,831 | $0.54M | 0.0% | N/A | 0.049% |  |
| 2/16/2026 | Panagora Asset Management Inc. | 74,055 | $1.73M | 0.0% | -59.8% | 0.158% |  |
| 2/16/2026 | MML Investors Services LLC | 24,363 | $0.57M | 0.0% | N/A | 0.052% |  |
| 2/16/2026 | Healthcare of Ontario Pension Plan Trust Fund | 1,125,100 | $26.35M | 0.0% | N/A | 2.404% |  |
| 2/16/2026 | Barclays PLC | 57,744 | $1.35M | 0.0% | +3.8% | 0.123% |  |
| 2/13/2026 | Marshall Wace LLP | 16,300 | $0.38M | 0.0% | -12.7% | 0.035% |  |
| 2/13/2026 | The Manufacturers Life Insurance Company | 55,686 | $1.29M | 0.0% | +55.0% | 0.119% |  |
| 2/13/2026 | Morgan Stanley | 2,562,901 | $60.02M | 0.0% | +1.4% | 5.475% |  |
| 2/13/2026 | State Street Corp | 807,421 | $18.91M | 0.0% | -1.5% | 1.725% |  |
| 2/13/2026 | Wells Fargo & Company MN | 84,158 | $1.97M | 0.0% | -33.2% | 0.180% |  |
| 2/12/2026 | HRT Financial LP | 130,899 | $3.07M | 0.0% | -2.1% | 0.280% |  |
| 2/12/2026 | Orion Porfolio Solutions LLC | 9,008 | $0.21M | 0.0% | -18.2% | 0.019% |  |
| 2/12/2026 | Renaissance Technologies LLC | 244,300 | $5.72M | 0.0% | -11.2% | 0.522% |  |
| 2/12/2026 | Annandale Capital LLC | 60,552 | $1.42M | 0.2% | -14.2% | 0.129% |  |
| 2/12/2026 | Informed Momentum Co LLC | 160,412 | $3.76M | 0.4% | N/A | 0.343% |  |
| 2/12/2026 | New York State Common Retirement Fund | 12,737 | $0.30M | 0.0% | +62.5% | 0.027% |  |
| 2/12/2026 | Nuveen LLC | 302,601 | $7.09M | 0.0% | -40.4% | 0.646% |  |
| 2/11/2026 | ARK Investment Management LLC | 121,484 | $2.85M | 0.0% | -4.1% | 0.260% |  |
| 2/11/2026 | Deutsche Bank AG | 366,680 | $8.59M | 0.0% | +126.0% | 0.783% |  |
| 2/11/2026 | Franklin Resources Inc. | 16,745 | $0.39M | 0.0% | N/A | 0.036% |  |
| 2/11/2026 | JPMorgan Chase & Co. | 146,271 | $3.43M | 0.0% | -72.6% | 0.312% |  |
| 2/11/2026 | WINTON GROUP Ltd | 13,188 | $0.31M | 0.0% | N/A | 0.028% |  |
| 2/10/2026 | TD Asset Management Inc | 80,188 | $1.88M | 0.0% | +82.2% | 0.171% |  |
| 2/10/2026 | Goldman Sachs Group Inc. | 459,722 | $10.77M | 0.0% | +8.2% | 0.982% |  |
| 2/10/2026 | Intech Investment Management LLC | 22,210 | $0.52M | 0.0% | +45.9% | 0.047% |  |
| 2/9/2026 | Geode Capital Management LLC | 475,212 | $11.13M | 0.0% | +0.8% | 1.015% |  |
| 2/6/2026 | ProShare Advisors LLC | 8,812 | $0.21M | 0.0% | N/A | 0.019% |  |
| 2/5/2026 | DNB Asset Management AS | 16,961 | $0.40M | 0.0% | N/A | 0.036% |  |
| 2/3/2026 | Privium Fund Management B.V. | 214,622 | $5.03M | 0.9% | +9.2% | 0.458% |  |
| 2/2/2026 | Oppenheimer & Co. Inc. | 16,962 | $0.40M | 0.0% | N/A | 0.036% |  |
| 1/29/2026 | UBS Group AG | 235,040 | $5.51M | 0.0% | +30.2% | 0.502% |  |
| 1/29/2026 | China Universal Asset Management Co. Ltd. | 7,627 | $0.18M | 0.0% | -5.9% | 0.016% |  |