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ZYME Insider Trading

Insider Ownership Percentage: 33.51%
Insider Buying (Last 12 Months): $16,773,032.28
Insider Selling (Last 12 Months): $4,673,716.04

Zymeworks Insider Trading History Chart

This chart shows the insider buying and selling history at Zymeworks by year and by quarter.

Skip ChartChart Data in Insider Trading History Table

Zymeworks Share Price & Price History

Current Price: $23.63
Price Change: ▲ Price Increase of +0.64 (2.78%)
As of 02/24/2026 05:00 PM ET

This chart shows the closing price history over time for ZYME up to the past year.

Skip Chart and Table DataPrice Data in Insider Trading History Table
Days: 30 | 90 | 365

Zymeworks Insider Trading History

Transaction DateInsider NameTitleBuy/SellNumber of SharesAverage Share PriceTotal TransactionShares Held After TransactionDetails
1/12/2026Jeffrey T. L. SmithEVPSell9,310$22.67$211,057.7026,708View SEC Filing Icon  
1/12/2026Kenneth GalbraithCEOSell30,424$22.67$689,712.08226,842View SEC Filing Icon  
1/12/2026Mark HollywoodCOOSell6,120$22.67$138,740.40132,913View SEC Filing Icon  
1/12/2026Paul Andrew MooreInsiderSell9,560$22.67$216,725.2048,497View SEC Filing Icon  
1/5/2026Jeffrey T. L. SmithEVPSell10,538$25.10$264,503.8018,352View SEC Filing Icon  
1/5/2026Kenneth GalbraithCEOSell54,343$25.10$1,364,009.30158,286View SEC Filing Icon  
1/5/2026Paul Andrew MooreInsiderSell20,110$25.10$504,761.0031,212View SEC Filing Icon  
12/22/2025Kenneth GalbraithCEOSell47,528$27.02$1,284,206.56133,275View SEC Filing Icon  
5/19/2025Ecor1 Capital, LlcDirectorBuy5,919$11.78$69,725.8217,883,908View SEC Filing Icon  
5/15/2025Ecor1 Capital, LlcDirectorBuy49,502$11.43$565,807.8617,877,989View SEC Filing Icon  
4/16/2025Ecor1 Capital, LlcDirectorBuy73,953$11.16$825,315.4817,773,727View SEC Filing Icon  
4/4/2025Ecor1 Capital, LlcDirectorBuy196,438$11.17$2,194,212.4617,699,774View SEC Filing Icon  
4/2/2025Ecor1 Capital, LlcDirectorBuy74,360$11.85$881,166.0017,382,566View SEC Filing Icon  
3/31/2025Ecor1 Capital, LlcDirectorBuy4,397$11.75$51,664.7517,259,548View SEC Filing Icon  
3/26/2025Ecor1 Capital, LlcDirectorBuy43,848$12.24$536,699.5217,255,151View SEC Filing Icon  
3/24/2025Ecor1 Capital, LlcDirectorBuy22,689$13.08$296,772.1217,157,802View SEC Filing Icon  
3/21/2025Ecor1 Capital, LlcDirectorBuy31,033$12.78$396,601.7417,135,113View SEC Filing Icon  
3/19/2025Ecor1 Capital, LlcDirectorBuy58,306$12.64$736,987.8417,030,604View SEC Filing Icon  
3/17/2025Ecor1 Capital, LlcDirectorBuy56,277$12.23$688,267.7116,858,418View SEC Filing Icon  
3/13/2025Ecor1 Capital, LlcDirectorBuy468,356$12.48$5,845,082.8816,802,141View SEC Filing Icon  
3/11/2025Ecor1 Capital, LlcDirectorBuy320,690$11.49$3,684,728.1016,040,851View SEC Filing Icon  
1/17/2025Ecor1 Capital, LlcDirectorBuy19,748$13.87$273,904.7615,720,161View SEC Filing Icon  
1/15/2025Ecor1 Capital, LlcDirectorBuy39,029$14.01$546,796.2915,578,732View SEC Filing Icon  
1/13/2025Ecor1 Capital, LlcDirectorBuy74,125$13.39$992,533.7515,485,203View SEC Filing Icon  
1/10/2025Ecor1 Capital, LlcDirectorBuy204,098$13.13$2,679,806.7415,411,078View SEC Filing Icon  
1/8/2025Ecor1 Capital, LlcDirectorBuy21,021$14.07$295,765.4715,206,980View SEC Filing Icon  
1/6/2025Jeffrey T. L. SmithEVPSell11,110$14.92$165,761.208,890View SEC Filing Icon  
1/6/2025Kenneth GalbraithCEOSell57,291$14.92$854,781.7247,543View SEC Filing Icon  
1/6/2025Paul Andrew MooreInsiderSell21,200$14.92$316,304.0014,741View SEC Filing Icon  
1/2/2025Ecor1 Capital, LlcDirectorBuy157,880$14.78$2,333,466.4015,185,959View SEC Filing Icon  
12/30/2024Ecor1 Capital, LlcDirectorBuy58,988$14.47$853,556.3614,881,578View SEC Filing Icon  
12/26/2024Ecor1 Capital, LlcDirectorBuy16,692$14.38$240,030.9614,720,931View SEC Filing Icon  
12/24/2024Ecor1 Capital, LlcDirectorBuy11,958$14.12$168,846.9614,704,239View SEC Filing Icon  
1/8/2024Christopher AstleCFOSell1,431$11.22$16,055.826,503View SEC Filing Icon  
1/8/2024Kenneth GalbraithCEOSell5,706$11.22$64,021.3223,762View SEC Filing Icon  
1/8/2024Paul Andrew MooreInsiderSell2,339$11.22$26,243.587,367View SEC Filing Icon  
1/5/2024Christopher AstleCFOSell4,563$10.65$48,595.957,934View SEC Filing Icon  
1/5/2024Kenneth GalbraithCEOSell18,198$10.65$193,808.7029,468View SEC Filing Icon  
1/5/2024Paul Andrew MooreInsiderSell7,460$10.65$79,449.009,706View SEC Filing Icon  
12/11/2023Christopher AstleCFOSell886$9.13$8,089.181,997View SEC Filing Icon  
6/16/2023Ecor1 Capital, LlcMajor ShareholderBuy3,350,000$8.12$27,202,000.0013,437,473View SEC Filing Icon  
3/28/2023Ecor1 Capital, LlcMajor ShareholderBuy200,000$8.00$1,600,000.0010,087,473View SEC Filing Icon  
3/10/2023Neil A. KlompasCOOSell2,977$7.83$23,309.9117,032View SEC Filing Icon  
See Full Table

SEC Filings (Institutional Ownership Changes) for Zymeworks (NASDAQ:ZYME)

92.89% of Zymeworks stock is owned by institutions. Institutional ownership can be a sign of analyst confidence in the fundamentals of the stock.

Institutional Buying and Selling by Quarter

This chart shows the instiutional buying and selling at ZYME by year and by quarter.

Skip Institutional Buying and Selling Chart and Table DataRead Chart Data in Institutional Trading History Table

Zymeworks Institutional Trading History

Reporting DateHedge FundShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
2/19/2026Invesco Ltd.257,580$6.78M0.0%+175.0%0.344%Search for SEC Filing on Google Icon
2/18/2026Mackenzie Financial Corp45,460$1.20M0.0%-19.4%0.061%Search for SEC Filing on Google Icon
2/18/2026XTX Topco Ltd93,469$2.46M0.1%N/A0.125%Search for SEC Filing on Google Icon
2/18/2026VARCOV Co.9,818$0.26M0.1%N/A0.013%Search for SEC Filing on Google Icon
2/18/2026Vestal Point Capital LP865,000$22.78M0.8%-51.0%1.156%Search for SEC Filing on Google Icon
2/18/2026Virtus Investment Advisers LLC10,441$0.28M0.1%+20.2%0.014%Search for SEC Filing on Google Icon
2/18/2026SummitTX Capital L.P.224,268$5.91M0.2%N/A0.300%Search for SEC Filing on Google Icon
2/18/2026Susquehanna Portfolio Strategies LLC99,795$2.63M0.0%+18.5%0.133%Search for SEC Filing on Google Icon
2/18/2026Tang Capital Management LLC34,631$0.91M0.0%-96.9%0.046%Search for SEC Filing on Google Icon
2/18/2026Tudor Investment Corp ET AL30,324$0.80M0.0%-19.3%0.041%Search for SEC Filing on Google Icon
2/18/2026Quadrature Capital Ltd23,017$0.61M0.0%N/A0.031%Search for SEC Filing on Google Icon
2/18/2026Opaleye Management Inc.108,929$2.87M0.4%+8.9%0.146%Search for SEC Filing on Google Icon
2/18/2026Perceptive Advisors LLC3,261,850$85.89M1.5%+56.0%4.359%Search for SEC Filing on Google Icon
2/18/2026Millennium Management LLC381,621$10.05M0.0%-65.5%0.510%Search for SEC Filing on Google Icon
2/18/2026Man Group plc75,318$1.98M0.0%-52.5%0.101%Search for SEC Filing on Google Icon
2/17/2026Schonfeld Strategic Advisors LLC288,571$7.60M0.0%+167.7%0.386%Search for SEC Filing on Google Icon
2/17/2026AQR Capital Management LLC91,075$2.40M0.0%-40.3%0.122%Search for SEC Filing on Google Icon
2/17/2026Lazard Asset Management LLC13,776$0.36M0.0%-10.0%0.018%Search for SEC Filing on Google Icon
2/17/2026Trexquant Investment LP101,274$2.67M0.0%N/A0.135%Search for SEC Filing on Google Icon
2/17/2026Price T Rowe Associates Inc. MD28,784$0.76M0.0%+7.3%0.038%Search for SEC Filing on Google Icon
2/17/2026Vinva Investment Management Ltd12,216$0.32M0.0%-16.3%0.016%Search for SEC Filing on Google Icon
2/17/2026Adage Capital Partners GP L.L.C.663,546$17.47M0.0%+17.7%0.887%Search for SEC Filing on Google Icon
2/17/2026California State Teachers Retirement System37,761$0.99M0.0%+7.2%0.050%Search for SEC Filing on Google Icon
2/17/2026Russell Investments Group Ltd.58,350$1.54M0.0%+1.6%0.078%Search for SEC Filing on Google Icon
2/17/2026Granahan Investment Management LLC224,408$5.91M0.3%-35.0%0.300%Search for SEC Filing on Google Icon
2/17/2026State of Wisconsin Investment Board75,566$1.99M0.0%+34.3%0.101%Search for SEC Filing on Google Icon
2/17/2026Royal Bank of Canada55,055$1.45M0.0%-5.0%0.074%Search for SEC Filing on Google Icon
2/16/2026Panagora Asset Management Inc.78,336$2.06M0.0%-26.1%0.105%Search for SEC Filing on Google Icon
2/16/2026Kennedy Capital Management LLC145,534$3.83M0.1%-0.6%0.194%Search for SEC Filing on Google Icon
2/16/2026Barclays PLC79,966$2.11M0.0%-59.8%0.107%Search for SEC Filing on Google Icon
2/13/2026Prosight Management LP530,393$13.97M2.9%-29.2%0.709%Search for SEC Filing on Google Icon
2/13/2026CreativeOne Wealth LLC18,264$0.48M0.0%N/A0.024%Search for SEC Filing on Google Icon
2/13/2026Rubric Capital Management LP5,750,000$151.40M1.8%+22.1%7.683%Search for SEC Filing on Google Icon
2/13/2026Stifel Financial Corp75,847$2M0.0%+4.6%0.101%Search for SEC Filing on Google Icon
2/13/2026Morgan Stanley2,593,080$68.28M0.0%-34.9%3.465%Search for SEC Filing on Google Icon
2/13/2026Schroder Investment Management Group97,907$2.60M0.0%-39.4%0.131%Search for SEC Filing on Google Icon
2/13/2026North Growth Management Ltd.45,000$1.18M0.2%-45.1%0.060%Search for SEC Filing on Google Icon
2/13/2026Siren L.L.C.1,680,121$44.24M1.3%N/A2.245%Search for SEC Filing on Google Icon
2/13/2026Charles Schwab Investment Management Inc.220,909$5.82M0.0%+14.2%0.295%Search for SEC Filing on Google Icon
2/13/2026Police & Firemen s Retirement System of New Jersey13,702$0.36M0.0%-3.5%0.018%Search for SEC Filing on Google Icon
2/13/2026State Street Corp1,037,642$27.32M0.0%-4.0%1.387%Search for SEC Filing on Google Icon
2/13/2026Caitong International Asset Management Co. Ltd2,073$55K0.2%N/A0.003%Search for SEC Filing on Google Icon
2/13/2026UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC320,261$8.43M0.0%-81.3%0.428%Search for SEC Filing on Google Icon
2/13/2026Wells Fargo & Company MN208,313$5.49M0.0%+17.9%0.278%Search for SEC Filing on Google Icon
2/13/2026Platinum Investment Management Ltd.105,184$2.77M0.6%-15.7%0.141%Search for SEC Filing on Google Icon
2/12/2026Northwest & Ethical Investments L.P.12,044$0.32M0.0%+20.1%0.016%Search for SEC Filing on Google Icon
2/12/2026Jane Street Group LLC70,445$1.86M0.0%-51.5%0.094%Search for SEC Filing on Google Icon
2/12/2026HRT Financial LP121,064$3.19M0.0%+76.8%0.162%Search for SEC Filing on Google Icon
2/12/2026Brooklyn Investment Group8,020$0.21M0.0%N/A0.011%Search for SEC Filing on Google Icon
2/12/2026MetLife Investment Management LLC28,630$0.75M0.0%-14.0%0.038%Search for SEC Filing on Google Icon
2/12/2026Commonwealth Equity Services LLC26,095$0.69M0.0%-16.5%0.035%Search for SEC Filing on Google Icon
2/12/2026Renaissance Technologies LLC220,877$5.82M0.0%-48.8%0.295%Search for SEC Filing on Google Icon
2/12/2026Dimensional Fund Advisors LP1,159,215$30.52M0.0%-2.7%1.549%Search for SEC Filing on Google Icon
2/12/2026Federated Hermes Inc.152,689$4.02M0.0%-16.5%0.204%Search for SEC Filing on Google Icon
2/12/2026New York State Common Retirement Fund17,371$0.46M0.0%+29.9%0.023%Search for SEC Filing on Google Icon
2/12/2026Campbell & CO Investment Adviser LLC33,588$0.88M0.0%+3.4%0.045%Search for SEC Filing on Google Icon
2/12/2026Bank of Montreal Can17,468$0.46M0.0%-36.8%0.023%Search for SEC Filing on Google Icon
2/12/2026Swiss National Bank74,200$1.95M0.0%+1.5%0.099%Search for SEC Filing on Google Icon
2/12/2026Nuveen LLC648,326$17.07M0.0%+14.7%0.866%Search for SEC Filing on Google Icon
2/11/2026Picton Mahoney Asset Management244,798$6.45M0.0%+18.6%0.327%Search for SEC Filing on Google Icon
2/11/2026Deutsche Bank AG1,595,833$42.02M0.0%+3.3%2.132%Search for SEC Filing on Google Icon
2/11/2026Franklin Resources Inc.58,987$1.55M0.0%+74.4%0.079%Search for SEC Filing on Google Icon
2/11/2026O Shaughnessy Asset Management LLC43,052$1.13M0.0%+3.1%0.058%Search for SEC Filing on Google Icon
2/11/2026WINTON GROUP Ltd11,180$0.29M0.0%N/A0.015%Search for SEC Filing on Google Icon
2/11/2026State of Wyoming10,875$0.29M0.0%N/A0.015%Search for SEC Filing on Google Icon
2/10/2026Goldman Sachs Group Inc.420,207$11.06M0.0%-5.3%0.561%Search for SEC Filing on Google Icon
2/10/2026Hillsdale Investment Management Inc.237,922$6.26M0.2%+9.9%0.318%Search for SEC Filing on Google Icon
2/10/2026SBI Okasan Asset Management Co.Ltd.32,000$0.86M0.0%N/A0.043%Search for SEC Filing on Google Icon
2/10/2026Jupiter Asset Management Ltd.125,506$3.31M0.0%-64.2%0.168%Search for SEC Filing on Google Icon
2/10/2026Intech Investment Management LLC20,330$0.54M0.0%+19.7%0.027%Search for SEC Filing on Google Icon
2/9/2026Geode Capital Management LLC647,970$17.06M0.0%-4.5%0.866%Search for SEC Filing on Google Icon
2/9/2026Fisher Asset Management LLC68,197$1.80M0.0%-5.2%0.091%Search for SEC Filing on Google Icon
2/6/2026PSP Research LLC20,312$0.54M0.5%N/A0.027%Search for SEC Filing on Google Icon
2/6/2026ProShare Advisors LLC12,387$0.33M0.0%+10.6%0.017%Search for SEC Filing on Google Icon
2/5/2026Abacus Wealth Partners LLC10,222$0.27M0.0%N/A0.014%Search for SEC Filing on Google Icon
2/5/2026Dana Investment Advisors Inc.48,318$1.27M0.0%N/A0.065%Search for SEC Filing on Google Icon
2/5/2026Baader Bank Aktiengesellschaft10,013$0.26M0.0%N/A0.013%Search for SEC Filing on Google Icon
2/4/2026VIRGINIA RETIREMENT SYSTEMS ET Al27,935$0.74M0.0%-50.1%0.037%Search for SEC Filing on Google Icon
2/2/2026Strs Ohio26,600$0.70M0.0%-35.0%0.036%Search for SEC Filing on Google Icon
2/2/2026Kornitzer Capital Management Inc. KS88,800$2.34M0.0%N/A0.119%Search for SEC Filing on Google Icon
1/29/2026Pictet Asset Management Holding SA73,627$1.97M0.0%N/A0.098%Search for SEC Filing on Google Icon
1/29/2026UBS Group AG278,854$7.34M0.0%+437.9%0.373%Search for SEC Filing on Google Icon
1/29/2026Vanguard Group Inc.2,328,727$61.32M0.0%+8.1%3.112%Search for SEC Filing on Google Icon
1/29/2026China Universal Asset Management Co. Ltd.12,195$0.32M0.0%-7.4%0.016%Search for SEC Filing on Google Icon
1/28/2026Arizona State Retirement System10,395$0.27M0.0%-6.0%0.014%Search for SEC Filing on Google Icon
1/28/2026Universal Beteiligungs und Servicegesellschaft mbH32,815$0.86M0.0%+7.8%0.044%Search for SEC Filing on Google Icon
1/27/2026Zurcher Kantonalbank Zurich Cantonalbank 20,421$0.54M0.0%-31.3%0.027%Search for SEC Filing on Google Icon
1/26/2026Mirae Asset Global Investments Co. Ltd.3,637$96K0.0%+25.2%0.005%Search for SEC Filing on Google Icon
1/22/2026Massachusetts Financial Services Co. MA28,083$0.74M0.0%-3.2%0.038%Search for SEC Filing on Google Icon
1/22/2026Apollon Wealth Management LLC7,875$0.21M0.0%N/A0.011%Search for SEC Filing on Google Icon
1/21/2026Capricorn Fund Managers Ltd1,022,840$26.93M6.5%N/A1.367%Search for SEC Filing on Google Icon
1/16/2026Tema Etfs LLC75,975$2M0.2%+19.3%0.102%Search for SEC Filing on Google Icon
1/15/2026Allspring Global Investments Holdings LLC7,707$0.21M0.0%N/A0.010%Search for SEC Filing on Google Icon
1/9/2026SG Americas Securities LLC17,557$0.46M0.0%+28.9%0.023%Search for SEC Filing on Google Icon
1/9/2026Assenagon Asset Management S.A.647,374$17.05M0.0%-51.2%0.865%Search for SEC Filing on Google Icon
1/1/2026JPMorgan Chase & Co.33,884$0.58M0.0%-92.3%0.045%Search for SEC Filing on Google Icon
1/1/2026Tudor Investment Corp ET AL37,583$0.64M0.0%+9.6%0.050%Search for SEC Filing on Google Icon
12/9/2025Tudor Investment Corp ET AL37,583$0.64M0.0%+9.6%0.050%Search for SEC Filing on Google Icon
11/17/2025Dark Forest Capital Management LP37,167$0.64M0.0%-61.7%0.050%Search for SEC Filing on Google Icon
11/17/2025PharVision Advisers LLC17,790$0.30M0.2%N/A0.024%Search for SEC Filing on Google Icon
Data available starting January 2016

See Full Table
Zymeworks logo
Zymeworks Inc., a clinical-stage biopharmaceutical company, discovers, develops, and commercializes biotherapeutics for the treatment of cancer. The company's lead product candidates include zanidatamab, a novel bispecific antibody that is in Phase 1 and Phase 2 clinical trials for the treatment of biliary tract, gastroesophageal adenocarcinomas, and breast cancer; and ZW49, a biparatopic anti- human epidermal growth factor receptor 2 (HER2) antibody-drug conjugate that is in Phase 1 clinical trial for the treatment of advanced or metastatic HER2-expressing tumors. The company has strategic partnerships with Merck Sharp & Dohme Research Ltd.; Eli Lilly and Company; Bristol-Myers Squibb company; GlaxoSmithKline Intellectual Property Development Ltd.; Daiichi Sankyo Co., Ltd.; Janssen Biotech, Inc.; and BeiGene, Ltd. It also has licensing and research collaboration with LEO Pharma A/S to discover and develop bispecific antibodies; and Iconic Therapeutics, Inc. Zymeworks Inc. was founded in 2003 and is headquartered in Vancouver, Canada.
Read More on Zymeworks

Today's Range

Now: $23.63
Low: $22.80
High: $23.68

50 Day Range

MA: $24.19
Low: $22.02
High: $27.62

52 Week Range

Now: $23.63
Low: $9.03
High: $28.49

Volume

445,321 shs

Average Volume

777,076 shs

Market Capitalization

$1.77 billion

P/E Ratio

N/A

Dividend Yield

N/A

Beta

1.25

Who are the company insiders with the largest holdings of Zymeworks?

Zymeworks' top insider shareholders include:
  1. Ecor1 Capital, Llc (Director)
  2. Kenneth Galbraith (CEO)
  3. Mark Hollywood (COO)
  4. Paul Andrew Moore (Insider)
  5. Jeffrey T L Smith (EVP)
Learn More about top insider investors at Zymeworks.

Who are the major institutional investors of Zymeworks?

Zymeworks' top institutional shareholders include:
  1. Rubric Capital Management LP — 7.68%
  2. Perceptive Advisors LLC — 4.36%
  3. Morgan Stanley — 3.46%
  4. Vanguard Group Inc. — 3.11%
  5. Siren L.L.C. — 2.25%
  6. Deutsche Bank AG — 2.13%
Learn More about top institutional investors of Zymeworks stock.

Which major investors are selling Zymeworks stock?

During the last quarter, ZYME stock was sold by these institutional investors:
  1. Morgan Stanley
  2. UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC
  3. Tang Capital Management LLC
  4. Vestal Point Capital LP
  5. Millennium Management LLC
  6. Assenagon Asset Management S.A.
  7. Jupiter Asset Management Ltd.
  8. Prosight Management LP
Within the previous year, company insiders that have sold Zymeworks company stock include:
  1. Ecor1 Capital, Llc (Director)
  2. Kenneth Galbraith (CEO)
  3. Mark Hollywood (COO)
  4. Paul Andrew Moore (Insider)
Learn More investors selling Zymeworks stock.

Which major investors are buying Zymeworks stock?

In the last quarter, ZYME stock was purchased by institutional investors including:
  1. Siren L.L.C.
  2. Perceptive Advisors LLC
  3. Rubric Capital Management LP
  4. Capricorn Fund Managers Ltd
  5. UBS Group AG
  6. SummitTX Capital L.P.
  7. Schonfeld Strategic Advisors LLC
  8. Vanguard Group Inc.