| 9/9/2026 | Opaleye Management Inc. | 1,714,451 | $9.79M | 0.9% | -26.5% | 0.904% |  |
| 9/9/2026 | WINTON GROUP Ltd | 47,800 | $0.27M | 0.0% | +98.3% | 0.025% |  |
| 9/9/2026 | Engineers Gate Manager LP | 319,057 | $1.82M | 0.0% | +83.2% | 0.168% |  |
| 9/9/2026 | Integrated Wealth Concepts LLC | 13,537 | $77K | 0.0% | +32.3% | 0.007% |  |
| 9/9/2026 | Squarepoint Ops LLC | 173,285 | $0.99M | 0.0% | +155.0% | 0.091% |  |
| 8/25/2026 | VIRGINIA RETIREMENT SYSTEMS ET Al | 54,300 | $0.31M | 0.0% | N/A | 0.029% |  |
| 8/20/2026 | Susquehanna Fundamental Investments LLC | 21,010 | $0.12M | 0.0% | N/A | 0.011% |  |
| 8/20/2026 | Moore Capital Management LP | 425,332 | $2.43M | 0.0% | N/A | 0.224% |  |
| 8/19/2026 | UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 180,647 | $1.03M | 0.0% | +38.3% | 0.095% |  |
| 8/19/2026 | Wellington Management Group LLP | 406,795 | $2.32M | 0.0% | -22.0% | 0.215% |  |
| 8/18/2026 | Palo Alto Investors LP | 2,948,090 | $16.83M | 0.0% | N/A | 1.555% |  |
| 8/18/2026 | Coastal Bridge Advisors LLC | 17,000 | $97K | 0.0% | N/A | 0.009% |  |
| 8/17/2026 | Corient Private Wealth LP | 19,704 | $0.11M | 0.0% | N/A | 0.010% |  |
| 8/17/2026 | Bank of America Corp DE | 614,186 | $3.51M | 0.0% | N/A | 0.324% |  |
| 8/15/2026 | Jupiter Topco LLC | 59,100 | $0.34M | 0.0% | N/A | 0.031% |  |
| 8/15/2026 | J. Goldman & Co LP | 116,046 | $0.66M | 0.0% | N/A | 0.061% |  |
| 8/14/2026 | Canada Pension Plan Investment Board | 38,600 | $0.22M | 0.0% | N/A | 0.024% |  |
| 8/14/2026 | Parkman Healthcare Partners LLC | 641,029 | $3.66M | 0.4% | N/A | 0.391% |  |
| 8/14/2026 | Legal & General Group Plc | 98,118 | $0.56M | 0.0% | N/A | 0.060% |  |
| 8/14/2026 | The Manufacturers Life Insurance Company | 41,517 | $0.24M | 0.0% | N/A | 0.025% |  |
| 8/13/2026 | Forefront Analytics LLC | 14,240 | $81K | 0.1% | N/A | 0.009% |  |
| 8/12/2026 | Landscape Capital Management L.L.C. | 20,813 | $0.12M | 0.0% | N/A | 0.013% |  |
| 8/12/2026 | Ieq Capital LLC | 120,010 | $0.69M | 0.0% | N/A | 0.073% |  |
| 8/11/2026 | E Fund Management Co. Ltd. | 24,433 | $0.14M | 0.0% | N/A | 0.015% |  |
| 8/7/2026 | BlackRock Inc. | 13,539,744 | $77.31M | 0.0% | N/A | 8.264% |  |
| 8/7/2026 | Deutsche Bank AG | 616,489 | $3.52M | 0.0% | N/A | 0.376% |  |
| 8/6/2026 | SCS Capital Management LLC | 99,000 | $0.57M | 0.0% | N/A | 0.060% |  |
| 8/6/2026 | Bank of New York Mellon Corp | 501,442 | $2.86M | 0.0% | N/A | 0.306% |  |
| 8/6/2026 | State of Wyoming | 19,479 | $0.11M | 0.0% | N/A | 0.012% |  |
| 8/6/2026 | GSA Capital Partners LLP | 104,378 | $0.60M | 0.0% | N/A | 0.064% |  |
| 7/9/2026 | Hennion & Walsh Asset Management Inc. | 507,050 | $2.90M | 0.1% | -0.5% | 0.309% |  |
| 5/19/2026 | Bank of America Corp DE | 4,259,995 | $23.60M | 0.0% | +165.3% | 2.600% |  |
| 5/19/2026 | Janus Henderson Group PLC | 59,100 | $0.33M | 0.0% | N/A | 0.036% |  |
| 5/18/2026 | ADAR1 Capital Management LLC | 55,000 | $0.31M | 0.0% | +14.6% | 0.034% |  |
| 5/18/2026 | Redmile Group LLC | 14,549,768 | $80.61M | 5.3% | +44.8% | 8.880% |  |
| 5/16/2026 | The Manufacturers Life Insurance Company | 134,786 | $0.75M | 0.0% | +3.6% | 0.082% |  |
| 5/14/2026 | Renaissance Technologies LLC | 544,300 | $3.02M | 0.0% | -32.2% | 0.332% |  |
| 5/14/2026 | Siren L.L.C. | 3,958,646 | $21.93M | 0.6% | N/A | 2.416% |  |
| 5/14/2026 | Sei Investments Co. | 203,236 | $1.13M | 0.0% | +248.8% | 0.124% |  |
| 5/14/2026 | Lido Advisors LLC | 31,000 | $0.17M | 0.0% | -11.3% | 0.019% |  |
| 5/7/2026 | Dimensional Fund Advisors LP | 924,078 | $5.12M | 0.0% | +28.6% | 0.569% |  |
| 5/7/2026 | AlphaCentric Advisors LLC | 24,518 | $0.14M | 0.1% | N/A | 0.015% |  |
| 5/7/2026 | Swiss National Bank | 236,000 | $1.31M | 0.0% | N/A | 0.145% |  |
| 5/5/2026 | Bank of New York Mellon Corp | 395,019 | $2.19M | 0.0% | +9.2% | 0.243% |  |
| 5/4/2026 | J. Safra Sarasin Holding AG | 90,487 | $0.50M | 0.0% | -23.2% | 0.056% |  |
| 5/1/2026 | Fifth Third Bancorp | 35,398 | $0.20M | 0.0% | N/A | 0.022% |  |
| 4/28/2026 | Abel Hall LLC | 10,921 | $61K | 0.0% | N/A | 0.007% |  |
| 4/27/2026 | Y Intercept Hong Kong Ltd | 1,319,913 | $7.31M | 0.1% | N/A | 0.812% |  |
| 4/25/2026 | Strs Ohio | 55,500 | $0.31M | 0.0% | N/A | 0.034% |  |
| 4/22/2026 | Pictet Asset Management Holding SA | 16,701 | $93K | 0.0% | N/A | 0.010% |  |
| 3/3/2026 | Caitong International Asset Management Co. Ltd | 19,197 | $96K | 0.0% | N/A | 0.016% |  |
| 2/19/2026 | Invesco Ltd. | 972,449 | $4.88M | 0.0% | +381.5% | 0.813% |  |
| 2/18/2026 | Mercer Global Advisors Inc. ADV | 10,386 | $52K | 0.0% | N/A | 0.009% |  |
| 2/18/2026 | XTX Topco Ltd | 243,313 | $1.22M | 0.0% | +64.6% | 0.203% |  |
| 2/18/2026 | Ikarian Capital LLC | 230,244 | $1.16M | 0.1% | N/A | 0.192% |  |
| 2/18/2026 | Virtus Investment Advisers LLC | 53,527 | $0.27M | 0.1% | +27.5% | 0.045% |  |
| 2/18/2026 | Wellington Management Group LLP | 398,077 | $2M | 0.0% | N/A | 0.333% |  |
| 2/18/2026 | SummitTX Capital L.P. | 438,497 | $2.20M | 0.1% | +81.2% | 0.367% |  |
| 2/18/2026 | Susquehanna Portfolio Strategies LLC | 356,619 | $1.79M | 0.0% | +0.8% | 0.298% |  |
| 2/18/2026 | Sphera Funds Management LTD. | 1,316,212 | $6.61M | 1.2% | -26.6% | 1.100% |  |
| 2/18/2026 | Quadrature Capital Ltd | 48,573 | $0.24M | 0.0% | N/A | 0.041% |  |
| 2/18/2026 | Millennium Management LLC | 2,836,857 | $14.24M | 0.0% | +0.5% | 2.371% |  |
| 2/18/2026 | Ishara Investments LP | 750,000 | $3.77M | 4.4% | N/A | 0.627% |  |
| 2/18/2026 | Cinctive Capital Management LP | 358,986 | $1.80M | 0.1% | +448.4% | 0.300% |  |
| 2/18/2026 | Balyasny Asset Management L.P. | 3,299,256 | $16.56M | 0.0% | +154.3% | 2.758% |  |
| 2/18/2026 | Boothbay Fund Management LLC | 64,069 | $0.32M | 0.0% | N/A | 0.054% |  |
| 2/18/2026 | BVF Inc. IL | 9,128,080 | $45.82M | 1.5% | +30.4% | 7.630% |  |
| 2/17/2026 | ADAR1 Capital Management LLC | 48,000 | $0.24M | 0.0% | N/A | 0.040% |  |
| 2/17/2026 | Schonfeld Strategic Advisors LLC | 522,846 | $2.63M | 0.0% | +146.4% | 0.437% |  |
| 2/17/2026 | J. Goldman & Co LP | 993,795 | $4.99M | 0.1% | -10.2% | 0.831% |  |
| 2/17/2026 | AQR Capital Management LLC | 776,307 | $3.90M | 0.0% | +35.2% | 0.649% |  |
| 2/17/2026 | Mak Capital One LLC | 2,958,527 | $14.85M | 1.6% | N/A | 2.473% |  |
| 2/17/2026 | Jump Financial LLC | 122,858 | $0.62M | 0.0% | N/A | 0.103% |  |
| 2/17/2026 | Price T Rowe Associates Inc. MD | 445,074 | $2.24M | 0.0% | -8.2% | 0.372% |  |
| 2/17/2026 | Adage Capital Partners GP L.L.C. | 5,500,000 | $27.61M | 0.0% | +266.7% | 4.598% |  |
| 2/17/2026 | Russell Investments Group Ltd. | 683,016 | $3.43M | 0.0% | +3,648.7% | 0.571% |  |
| 2/17/2026 | Captrust Financial Advisors | 31,585 | $0.16M | 0.0% | N/A | 0.026% |  |
| 2/16/2026 | Mariner LLC | 31,335 | $0.16M | 0.0% | N/A | 0.026% |  |
| 2/16/2026 | Landscape Capital Management L.L.C. | 10,016 | $50K | 0.0% | N/A | 0.008% |  |
| 2/16/2026 | Barclays PLC | 289,963 | $1.46M | 0.0% | +96.0% | 0.242% |  |
| 2/13/2026 | Marshall Wace LLP | 520,998 | $2.62M | 0.0% | N/A | 0.436% |  |
| 2/13/2026 | The Manufacturers Life Insurance Company | 130,102 | $0.66M | 0.0% | -1.9% | 0.109% |  |
| 2/13/2026 | Quarry LP | 75,000 | $0.38M | 0.1% | -31.8% | 0.063% |  |
| 2/13/2026 | Jacobs Levy Equity Management Inc. | 683,879 | $3.43M | 0.0% | +2,927.5% | 0.572% |  |
| 2/13/2026 | Sirios Capital Management L P | 710,256 | $3.57M | 0.4% | -26.8% | 0.594% |  |
| 2/13/2026 | Rafferty Asset Management LLC | 141,644 | $0.71M | 0.0% | N/A | 0.118% |  |
| 2/13/2026 | Charles Schwab Investment Management Inc. | 1,057,060 | $5.31M | 0.0% | +33.8% | 0.884% |  |
| 2/13/2026 | State Street Corp | 4,652,185 | $23.35M | 0.0% | +126.9% | 3.889% |  |
| 2/13/2026 | Ieq Capital LLC | 182,982 | $0.92M | 0.0% | +21.7% | 0.153% |  |
| 2/13/2026 | Caitong International Asset Management Co. Ltd | 16,415 | $82K | 0.2% | N/A | 0.014% |  |
| 2/13/2026 | Wells Fargo & Company MN | 573,748 | $2.88M | 0.0% | +40.1% | 0.480% |  |
| 2/12/2026 | MetLife Investment Management LLC | 39,059 | $0.20M | 0.0% | -12.5% | 0.033% |  |
| 2/12/2026 | Renaissance Technologies LLC | 802,600 | $4.03M | 0.0% | +6.5% | 0.671% |  |
| 2/12/2026 | Dimensional Fund Advisors LP | 718,680 | $3.61M | 0.0% | -6.3% | 0.601% |  |
| 2/12/2026 | EntryPoint Capital LLC | 42,774 | $0.22M | 0.1% | +114.2% | 0.036% |  |
| 2/12/2026 | New York State Common Retirement Fund | 29,568 | $0.15M | 0.0% | -14.2% | 0.025% |  |
| 2/12/2026 | Nuveen LLC | 2,915,324 | $14.64M | 0.0% | +327.1% | 2.437% |  |
| 2/11/2026 | Deutsche Bank AG | 560,744 | $2.82M | 0.0% | -62.7% | 0.469% |  |
| 2/11/2026 | Cerity Partners LLC | 14,801 | $74K | 0.0% | N/A | 0.012% |  |
| 2/11/2026 | Landing Point Financial Group LLC | 34,900 | $0.18M | 0.1% | N/A | 0.029% |  |