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IONS Insider Trading

Insider Ownership Percentage: 2.60%
Insider Buying (Last 12 Months): $477,900.00
Insider Selling (Last 12 Months): $144,439,752.03

Ionis Pharmaceuticals Insider Trading History Chart

This chart shows the insider buying and selling history at Ionis Pharmaceuticals by year and by quarter.

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Ionis Pharmaceuticals Share Price & Price History

Current Price: $70.99
Price Change: ▼ Price Decrease of -0.33 (-0.46%)
As of 03/20/2026 05:00 PM ET

This chart shows the closing price history over time for IONS up to the past year.

Skip Chart and Table DataPrice Data in Insider Trading History Table
Days: 30 | 90 | 365

Ionis Pharmaceuticals Insider Trading History

Transaction DateInsider NameTitleBuy/SellNumber of SharesAverage Share PriceTotal TransactionShares Held After TransactionDetails
3/17/2026Elizabeth L. HougenEVPSell10,172$73.21$744,692.1282,660View SEC Filing Icon  
3/16/2026Elizabeth L. HougenEVPSell215,048$72.40$15,569,475.2092,832View SEC Filing Icon  
3/10/2026Brett P. MoniaCEOSell34,103$75.92$2,589,099.76242,662View SEC Filing Icon  
3/10/2026Kyle JenneEVPSell37,277$75.85$2,827,460.4511,714View SEC Filing Icon  
3/9/2026Brett P. MoniaCEOSell126,670$75.20$9,525,584.00242,662View SEC Filing Icon  
3/9/2026Patrick R. O'NeilEVPSell10,148$75.25$763,637.0062,211View SEC Filing Icon  
3/3/2026Allene M. DiazDirectorSell54,878$79.35$4,354,569.303,811View SEC Filing Icon  
3/3/2026C. Frank BennettEVPSell85,089$79.23$6,741,601.4780,554View SEC Filing Icon  
3/3/2026Shannon L. DeversEVPSell20,106$79.40$1,596,416.4022,541View SEC Filing Icon  
2/13/2026Eric SwayzeEVPSell15,642$81.76$1,278,889.9232,105View SEC Filing Icon  
2/11/2026B. Lynne Parshall, Esq.DirectorSell5,000$82.72$413,600.0056,344View SEC Filing Icon  
2/6/2026Brett P. MoniaCEOSell29,430$85.79$2,524,799.70254,497View SEC Filing Icon  
2/2/2026C. Frank BennettEVPSell85,089$82.93$7,056,430.7780,293View SEC Filing Icon  
1/30/2026Brett P. MoniaCEOSell62,970$82.72$5,208,878.40283,927View SEC Filing Icon  
1/30/2026Brian BirchlerEVPSell6,179$83.03$513,042.3766,247View SEC Filing Icon  
1/30/2026C. Frank BennettEVPSell5,885$82.95$488,160.75100,293View SEC Filing Icon  
1/30/2026C. Frank BennettEVPSell5,885$82.95$488,160.75100,293View SEC Filing Icon  
1/30/2026Elizabeth L. HougenEVPSell6,988$83.24$581,681.12132,881View SEC Filing Icon  
1/30/2026Eric SwayzeEVPSell6,179$82.93$512,424.4747,747View SEC Filing Icon  
1/30/2026Eugene SchneiderEVPSell6,179$83.45$515,637.5569,702View SEC Filing Icon  
1/30/2026Patrick R. O'NeilEVPSell6,179$83.53$516,131.8771,983View SEC Filing Icon  
1/30/2026Patrick R. O'NeilEVPSell6,179$83.53$516,131.8771,983View SEC Filing Icon  
1/22/2026Shannon L. DeversEVPSell3,977$81.34$323,489.1822,541View SEC Filing Icon  
1/16/2026Brett P. MoniaCEOSell44,034$74.82$3,294,623.88224,683View SEC Filing Icon  
1/16/2026Brian BirchlerEVPSell8,480$75.11$636,932.8060,435View SEC Filing Icon  
1/16/2026C. Frank BennettEVPSell8,977$75.15$674,621.5594,757View SEC Filing Icon  
1/16/2026Elizabeth L. HougenEVPSell12,922$75.22$971,992.84126,307View SEC Filing Icon  
1/16/2026Eric SwayzeEVPSell9,884$75.34$744,660.5641,935View SEC Filing Icon  
1/16/2026Eric SwayzeEVPSell49$75.97$3,722.53318View SEC Filing Icon  
1/16/2026Eugene SchneiderEVPSell9,302$75.59$703,138.1863,890View SEC Filing Icon  
1/16/2026Holly B. KordasiewiczEVPSell4,141$75.66$313,308.0614,718View SEC Filing Icon  
1/16/2026Kyle JenneEVPSell1,823$75.96$138,475.0816,389View SEC Filing Icon  
1/16/2026Patrick R. O'NeilEVPSell9,191$75.84$697,045.4466,171View SEC Filing Icon  
1/16/2026Shannon L. DeversEVPSell8,353$75.95$634,410.3526,518View SEC Filing Icon  
1/7/2026Shannon L. DeversEVPSell44,199$85.08$3,760,450.9217,494View SEC Filing Icon  
1/2/2026Eric SwayzeEVPSell23,463$79.12$1,856,392.5630,453View SEC Filing Icon  
12/1/2025Joseph H. WenderDirectorSell28,000$80.82$2,262,960.0036,035View SEC Filing Icon  
11/25/2025Shannon L. DeversEVPSell16,777$80.91$1,357,427.0717,494View SEC Filing Icon  
11/6/2025Brian BirchlerEVPSell8,000$76.17$609,360.0048,826View SEC Filing Icon  
11/6/2025Richard S. GearyEVPSell33,038$75.72$2,501,637.3659,657View SEC Filing Icon  
11/5/2025Richard S. GearyEVPSell1,601$75.01$120,091.0159,657View SEC Filing Icon  
11/3/2025Richard S. GearyEVPSell1,680$75.05$126,084.0059,657View SEC Filing Icon  
10/31/2025Joseph H. WenderDirectorSell11,200$75.16$841,792.0064,035View SEC Filing Icon  
10/31/2025Richard S. GearyEVPSell89,249$75.11$6,703,492.3959,657View SEC Filing Icon  
10/30/2025Joseph H. WenderDirectorSell16,800$73.26$1,230,768.0075,235View SEC Filing Icon  
10/16/2025Eric SwayzeEVPSell53$73.62$3,901.86256View SEC Filing Icon  
10/16/2025Shannon L. DeversEVPSell1,263$73.62$92,982.0617,494View SEC Filing Icon  
10/15/2025B. Lynne Parshall, Esq.DirectorSell5,000$71.74$358,700.0061,344View SEC Filing Icon  
10/15/2025Brian BirchlerEVPSell12,425$72.23$897,457.7556,826View SEC Filing Icon  
10/15/2025Shannon L. DeversEVPSell6,000$72.94$437,640.0015,937View SEC Filing Icon  
10/14/2025Brian BirchlerEVPSell11,475$72.03$826,544.2556,826View SEC Filing Icon  
10/6/2025Brett P. MoniaCEOSell437$69.26$30,266.62179,572View SEC Filing Icon  
10/6/2025Eric SwayzeEVPSell6,849$69.02$472,717.9830,453View SEC Filing Icon  
10/6/2025Patrick R. O'NeilEVPSell13,441$69.74$937,375.3453,889View SEC Filing Icon  
10/2/2025Eric SwayzeEVPSell12,972$66.23$859,135.5637,302View SEC Filing Icon  
10/2/2025Patrick R. O'NeilEVPSell64,664$67.69$4,377,106.1657,130View SEC Filing Icon  
10/1/2025Eric SwayzeEVPSell14,142$66.09$934,644.7837,302View SEC Filing Icon  
10/1/2025Joseph H. WenderDirectorSell16,800$65.50$1,100,400.0092,035View SEC Filing Icon  
9/30/2025Elizabeth L. HougenEVPSell49,800$65.26$3,249,948.00110,500View SEC Filing Icon  
9/30/2025Patrick R. O'NeilEVPSell14,827$64.68$959,010.3657,130View SEC Filing Icon  
9/30/2025Richard S. GearyEVPSell57,900$65.24$3,777,396.0079,657View SEC Filing Icon  
9/29/2025Patrick R. O'NeilEVPSell10,473$64.54$675,927.4257,130View SEC Filing Icon  
9/12/2025Patrick R. O'NeilEVPSell1,700$64.58$109,786.0057,130View SEC Filing Icon  
9/9/2025Patrick R. O'NeilEVPSell21,000$64.56$1,355,760.0057,130View SEC Filing Icon  
9/5/2025C. Frank BennettEVPSell6,000$59.60$357,600.0082,679View SEC Filing Icon  
9/3/2025Brett P. MoniaCEOSell203,814$60.32$12,294,060.48180,009View SEC Filing Icon  
9/3/2025C. Frank BennettEVPSell33,909$60.62$2,055,563.58101,570View SEC Filing Icon  
9/3/2025Eugene SchneiderEVPSell19,658$60.81$1,195,402.9851,507View SEC Filing Icon  
9/3/2025Joseph H. WenderDirectorSell11,200$60.14$673,568.00108,835View SEC Filing Icon  
9/3/2025Patrick R. O'NeilEVPSell76,850$60.97$4,685,544.505,655View SEC Filing Icon  
9/3/2025Shannon L. DeversEVPSell3,162$61.02$192,945.2415,009View SEC Filing Icon  
9/2/2025B. Lynne Parshall, Esq.DirectorSell20,000$50.91$1,018,200.0066,344View SEC Filing Icon  
9/2/2025C. Frank BennettEVPSell5,000$49.14$245,700.0088,679View SEC Filing Icon  
9/2/2025Eric SwayzeEVPSell11,130$49.67$552,827.1037,302View SEC Filing Icon  
9/2/2025Joseph H. WenderDirectorSell16,800$55.87$938,616.00120,035View SEC Filing Icon  
9/2/2025Patrick R. O'NeilEVPSell13,050$54.51$711,355.5057,130View SEC Filing Icon  
9/2/2025Richard S. GearyEVPSell10,000$50.37$503,700.0079,657View SEC Filing Icon  
8/22/2025Allene M. DiazDirectorSell1,427$42.53$60,690.3118,368View SEC Filing Icon  
8/18/2025C. Frank BennettEVPSell10,000$43.98$439,800.0093,466View SEC Filing Icon  
8/6/2025B. Lynne Parshall, Esq.DirectorSell5,000$41.93$209,650.0086,344View SEC Filing Icon  
8/5/2025Richard S. GearyEVPSell10,000$42.86$428,600.0089,492View SEC Filing Icon  
8/4/2025Eugene SchneiderEVPSell9,549$42.80$408,697.2051,507View SEC Filing Icon  
7/30/2025Brett P. MoniaCEOSell2,432$45.00$109,440.00179,820View SEC Filing Icon  
7/11/2025Brett P. MoniaCEOSell1,160$41.74$48,418.40179,820View SEC Filing Icon  
5/1/2025Michael R. HaydenDirectorBuy15,000$31.86$477,900.0050,219View SEC Filing Icon  
4/16/2025Brian BirchlerEVPSell680$28.37$19,291.6056,660View SEC Filing Icon  
3/11/2025Brett P. MoniaCEOSell140$32.32$4,524.80180,980View SEC Filing Icon  
2/20/2025Patrick R. O'NeilEVPSell1,207$32.35$39,046.4556,245View SEC Filing Icon  
2/4/2025Brett P. MoniaCEOSell38,843$31.65$1,229,380.95180,683View SEC Filing Icon  
2/4/2025Patrick R. O'NeilEVPSell6,165$31.62$194,937.3057,452View SEC Filing Icon  
1/31/2025Brett P. MoniaCEOSell13,242$32.45$429,702.90219,526View SEC Filing Icon  
1/31/2025Elizabeth L. HougenCFOSell1,523$32.44$49,406.12110,500View SEC Filing Icon  
1/31/2025Eric SwayzeEVPSell1,367$32.31$44,167.7748,017View SEC Filing Icon  
1/16/2025Brett P. MoniaCEOSell33,445$32.63$1,091,310.35207,396View SEC Filing Icon  
1/16/2025Elizabeth L. HougenCFOSell8,870$32.81$291,024.70107,885View SEC Filing Icon  
1/16/2025Eric SwayzeEVPSell7,154$32.84$234,937.3645,670View SEC Filing Icon  
12/23/2024Michael R. HaydenDirectorBuy5,000$36.22$181,100.0035,219View SEC Filing Icon  
11/12/2024Brett P. MoniaCEOSell6,630$38.05$252,271.50167,393View SEC Filing Icon  
11/12/2024Eric SwayzeEVPSell1,194$37.92$45,276.4833,713View SEC Filing Icon  
10/16/2024Eric SwayzeEVPSell53$38.31$2,030.43157View SEC Filing Icon  
8/28/2024Richard S. GearyEVPSell320$49.16$15,731.2085,154View SEC Filing Icon  
8/5/2024Richard S. GearyEVPSell2,430$48.00$116,640.0085,508View SEC Filing Icon  
7/16/2024Joseph Klein, IIIDirectorSell12,000$50.00$600,000.0016,346View SEC Filing Icon  
5/3/2024Joseph Klein, IIIDirectorSell6,000$42.71$256,260.0016,346View SEC Filing Icon  
4/16/2024Joseph BaroldiEVPSell4,006$41.60$166,649.6019,631View SEC Filing Icon  
2/16/2024Brett P. MoniaCEOSell387$44.49$17,217.63173,751View SEC Filing Icon  
2/2/2024Brett P. MoniaCEOSell23,501$49.37$1,160,244.37174,138View SEC Filing Icon  
2/2/2024Elizabeth L. HougenCFOSell2,125$49.54$105,272.5092,905View SEC Filing Icon  
2/2/2024Eric SwayzeEVPSell1,907$49.56$94,510.9234,324View SEC Filing Icon  
1/31/2024Eric SwayzeEVPSell10,773$52.00$560,196.0032,516View SEC Filing Icon  
1/25/2024Brett P. MoniaCEOSell2,285$51.75$118,248.75151,851View SEC Filing Icon  
1/25/2024Patrick R. O'NeilEVPSell6,450$51.75$333,787.5046,802View SEC Filing Icon  
1/17/2024Brett P. MoniaCEOSell32,059$50.42$1,616,414.78154,136View SEC Filing Icon  
1/17/2024Elizabeth L. HougenCFOSell8,683$50.42$437,796.8690,890View SEC Filing Icon  
1/17/2024Onaiza J. Cadoret-ManierEVPSell5,564$50.42$280,536.8833,810View SEC Filing Icon  
1/12/2024Eugene SchneiderEVPSell8,000$53.50$428,000.0038,170View SEC Filing Icon  
12/28/2023B. Lynne Parshall, Esq.DirectorSell42,525$50.19$2,134,329.7582,588View SEC Filing Icon  
12/26/2023B. Lynne Parshall, Esq.DirectorSell25,113$51.46$1,292,314.9882,588View SEC Filing Icon  
12/26/2023Patrick R. O'NeilEVPSell20,825$51.46$1,071,654.5040,355View SEC Filing Icon  
12/21/2023Brett P. MoniaCEOSell17,500$49.29$862,575.00118,111View SEC Filing Icon  
12/20/2023C. Frank BennettEVPSell6,500$49.64$322,660.0065,754View SEC Filing Icon  
12/14/2023Brett P. MoniaCEOSell24,000$49.58$1,189,920.00118,111View SEC Filing Icon  
11/15/2023Joseph Klein, IIIDirectorSell2,000$50.00$100,000.0016,346View SEC Filing Icon  
10/17/2023Eric SwayzeEVPSell52$47.95$2,493.4073View SEC Filing Icon  
10/12/2023Brett P. MoniaCEOSell3,770$46.00$173,420.00118,111View SEC Filing Icon  
9/28/2023C. Frank BennettEVPSell4,460$46.50$207,390.0065,754View SEC Filing Icon  
9/26/2023B. Lynne Parshall, Esq.DirectorSell10,000$45.13$451,300.0082,588View SEC Filing Icon  
8/1/2023Allene M. DiazDirectorSell657$41.05$26,969.8512,676View SEC Filing Icon  
7/18/2023Joseph Klein, IIIDirectorSell3,555$42.00$149,310.0020,346View SEC Filing Icon  
7/7/2023Brett P. MoniaCEOSell18,650$42.25$787,962.50121,724View SEC Filing Icon  
5/24/2023Patrick R. O'NeilEVPSell1,527$41.70$63,675.9040,355View SEC Filing Icon  
5/22/2023Brett P. MoniaCEOSell4,931$40.14$197,930.34140,374View SEC Filing Icon  
4/18/2023Brian BirchlerEVPSell672$36.50$24,528.0036,528View SEC Filing Icon  
See Full Table

SEC Filings (Institutional Ownership Changes) for Ionis Pharmaceuticals (NASDAQ:IONS)

93.86% of Ionis Pharmaceuticals stock is owned by institutions. Institutional ownership can be a sign of analyst confidence in the fundamentals of the stock.

Institutional Buying and Selling by Quarter

This chart shows the instiutional buying and selling at IONS by year and by quarter.

Skip Institutional Buying and Selling Chart and Table DataRead Chart Data in Institutional Trading History Table

Ionis Pharmaceuticals Institutional Trading History

Reporting DateHedge FundShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
3/20/2026Hsbc Holdings PLC26,941$2.14M0.0%-40.7%0.016%Search for SEC Filing on Google Icon
3/17/2026Rockefeller Capital Management L.P.2,726$0.22M0.0%+23.7%0.002%Search for SEC Filing on Google Icon
3/9/2026Corient Private Wealth LLC216,438$17.12M0.0%+3,184.3%0.131%Search for SEC Filing on Google Icon
3/6/2026Hsbc Holdings PLC26,941$2.14M0.0%-40.7%0.016%Search for SEC Filing on Google Icon
2/27/2026Groupama Asset Managment766,889$60.67M0.9%-27.8%0.473%Search for SEC Filing on Google Icon
2/26/2026Alpine Global Management LLC53,600$4.24M0.7%-4.1%0.033%Search for SEC Filing on Google Icon
2/19/2026T. Rowe Price Investment Management Inc.9,108,019$720.54M0.5%-30.8%5.623%Search for SEC Filing on Google Icon
2/19/2026Axxcess Wealth Management LLC2,877$0.23M0.0%N/A0.002%Search for SEC Filing on Google Icon
2/19/2026Corient Private Wealth LLC214,936$17M0.0%+3,161.5%0.133%Search for SEC Filing on Google Icon
2/18/2026Mercer Global Advisors Inc. ADV5,554$0.44M0.0%+48.2%0.003%Search for SEC Filing on Google Icon
2/18/2026Vident Advisory LLC10,235$0.81M0.0%-11.4%0.006%Search for SEC Filing on Google Icon
2/18/2026Mackenzie Financial Corp3,891$0.31M0.0%+8.4%0.002%Search for SEC Filing on Google Icon
2/18/2026ADAR1 Capital Management LLC147,130$11.64M0.9%+9.9%0.091%Search for SEC Filing on Google Icon
2/18/2026Empowered Funds LLC24,671$1.95M0.0%N/A0.015%Search for SEC Filing on Google Icon
2/18/2026XTX Topco Ltd16,917$1.34M0.0%N/A0.010%Search for SEC Filing on Google Icon
2/18/2026Zurich Insurance Group Ltd FI261,820$20.71M0.1%N/A0.162%Search for SEC Filing on Google Icon
2/18/2026Voloridge Investment Management LLC584,970$46.28M0.2%-27.2%0.361%Search for SEC Filing on Google Icon
2/18/2026Virtus Investment Advisers LLC8,454$0.67M0.2%-32.2%0.005%Search for SEC Filing on Google Icon
2/18/2026Tudor Investment Corp ET AL3,661$0.29M0.0%N/A0.002%Search for SEC Filing on Google Icon
2/18/2026Summit Securities Group LLC748$59K0.0%N/A0.000%Search for SEC Filing on Google Icon
2/18/2026Janus Henderson Group PLC68,191$5.40M0.0%+6.8%0.042%Search for SEC Filing on Google Icon
2/18/2026Gotham Asset Management LLC43,212$3.42M0.0%+34.4%0.027%Search for SEC Filing on Google Icon
2/18/2026Engineers Gate Manager LP22,191$1.76M0.0%-13.9%0.014%Search for SEC Filing on Google Icon
2/18/2026Eversept Partners LP538,218$42.58M2.1%-0.1%0.332%Search for SEC Filing on Google Icon
2/18/2026Cinctive Capital Management LP13,726$1.09M0.1%-92.1%0.008%Search for SEC Filing on Google Icon
2/18/2026Artia Global Partners LP144,376$11.42M1.6%+139.9%0.089%Search for SEC Filing on Google Icon
2/18/2026Baker BROS. Advisors LP1,791,841$141.75M0.8%+216.1%1.106%Search for SEC Filing on Google Icon
2/18/2026Bamco Inc. NY36,000$2.85M0.0%+44.0%0.022%Search for SEC Filing on Google Icon
2/17/2026Guggenheim Capital LLC37,709$2.98M0.0%+6.7%0.023%Search for SEC Filing on Google Icon
2/17/2026ADAR1 Capital Management LLC147,130$11.64M0.8%+9.9%0.091%Search for SEC Filing on Google Icon
2/17/2026AQR Capital Management LLC18,762$1.48M0.0%+175.3%0.012%Search for SEC Filing on Google Icon
2/17/2026Cetera Investment Advisers10,856$0.86M0.0%+58.0%0.007%Search for SEC Filing on Google Icon
2/17/2026EFG International AG75,276$5.96M0.1%N/A0.046%Search for SEC Filing on Google Icon
2/17/2026Jain Global LLC356,259$28.18M0.1%+57.8%0.220%Search for SEC Filing on Google Icon
2/17/2026Quantedge Capital Pte Ltd18,500$1.46M0.7%N/A0.011%Search for SEC Filing on Google Icon
2/17/2026Trexquant Investment LP132,241$10.46M0.1%-38.5%0.082%Search for SEC Filing on Google Icon
2/17/2026Price T Rowe Associates Inc. MD2,987,840$236.37M0.0%+9.5%1.845%Search for SEC Filing on Google Icon
2/17/2026T. Rowe Price Investment Management Inc.5,789,863$458.04M0.5%-56.0%3.575%Search for SEC Filing on Google Icon
2/17/2026Osaic Holdings Inc.11,646$0.92M0.0%+14.5%0.007%Search for SEC Filing on Google Icon
2/17/2026Adage Capital Partners GP L.L.C.140,000$11.08M0.0%-89.4%0.086%Search for SEC Filing on Google Icon
2/17/2026Public Employees Retirement System of Ohio47,598$3.77M0.0%-2.0%0.029%Search for SEC Filing on Google Icon
2/17/2026California State Teachers Retirement System144,173$11.41M0.0%-0.6%0.089%Search for SEC Filing on Google Icon
2/17/2026Russell Investments Group Ltd.43,912$3.47M0.0%-43.2%0.027%Search for SEC Filing on Google Icon
2/17/2026Captrust Financial Advisors5,293$0.42M0.0%N/A0.003%Search for SEC Filing on Google Icon
2/17/2026Artisan Partners Limited Partnership1,181,416$93.46M0.1%+32.7%0.729%Search for SEC Filing on Google Icon
2/17/2026Fred Alger Management LLC38,423$3.04M0.0%-9.4%0.024%Search for SEC Filing on Google Icon
2/17/2026&PARTNERS9,723$0.77M0.0%-23.2%0.006%Search for SEC Filing on Google Icon
2/17/2026ExodusPoint Capital Management LP83,875$6.64M0.1%-44.9%0.052%Search for SEC Filing on Google Icon
2/17/2026Blair William & Co. IL33,788$2.67M0.0%-1.7%0.021%Search for SEC Filing on Google Icon
2/17/2026Graham Capital Management L.P.7,596$0.60M0.0%-55.7%0.005%Search for SEC Filing on Google Icon
2/17/2026Polar Capital Holdings Plc1,333,424$105.49M0.4%+29.0%0.823%Search for SEC Filing on Google Icon
2/16/2026Vanguard Personalized Indexing Management LLC12,461$0.99M0.0%+3.1%0.008%Search for SEC Filing on Google Icon
2/16/2026Verition Fund Management LLC22,685$1.80M0.0%-39.0%0.014%Search for SEC Filing on Google Icon
2/16/2026PEAK6 LLC30,642$2.42M0.0%+14.3%0.019%Search for SEC Filing on Google Icon
2/16/2026Mariner LLC47,740$3.78M0.0%+97.1%0.029%Search for SEC Filing on Google Icon
2/16/2026Healthcare of Ontario Pension Plan Trust Fund110,000$8.70M0.0%-5.2%0.068%Search for SEC Filing on Google Icon
2/16/2026Kennedy Capital Management LLC109,291$8.65M0.2%-11.0%0.067%Search for SEC Filing on Google Icon
2/16/2026Landscape Capital Management L.L.C.24,155$1.91M0.1%-9.1%0.015%Search for SEC Filing on Google Icon
2/16/2026Dymon Asia Capital Singapore PTE. LTD.5,350$0.42M0.0%N/A0.003%Search for SEC Filing on Google Icon
2/16/2026Eventide Asset Management LLC575,000$45.49M0.7%N/A0.355%Search for SEC Filing on Google Icon
2/16/2026Arax Advisory Partners774$61K0.0%N/A0.000%Search for SEC Filing on Google Icon
2/16/2026Brown Advisory Inc.14,965$1.18M0.0%+6.7%0.009%Search for SEC Filing on Google Icon
2/16/2026Aigen Investment Management LP8,861$0.70M0.2%-34.7%0.005%Search for SEC Filing on Google Icon
2/16/2026Arrowstreet Capital Limited Partnership1,063,327$84.12M0.0%+68.7%0.656%Search for SEC Filing on Google Icon
2/13/2026Kestra Advisory Services LLC4,451$0.35M0.0%-10.5%0.003%Search for SEC Filing on Google Icon
2/13/2026Marshall Wace LLP256,933$20.33M0.0%-73.2%0.159%Search for SEC Filing on Google Icon
2/13/2026The Manufacturers Life Insurance Company 153,241$12.11M0.0%+56.3%0.095%Search for SEC Filing on Google Icon
2/13/2026CANADA LIFE ASSURANCE Co20,894$1.65M0.0%-54.7%0.013%Search for SEC Filing on Google Icon
2/13/2026Inspire Advisors LLC4,851$0.38M0.0%N/A0.003%Search for SEC Filing on Google Icon
2/13/2026Bridgewater Associates LP67,706$5.36M0.0%+55.4%0.042%Search for SEC Filing on Google Icon
2/13/2026Stifel Financial Corp198,863$15.73M0.0%-1.9%0.123%Search for SEC Filing on Google Icon
2/13/2026Hudson Bay Capital Management LP475,000$37.58M0.1%-7.8%0.293%Search for SEC Filing on Google Icon
2/13/2026Commerce Bank8,111$0.64M0.0%+6.6%0.005%Search for SEC Filing on Google Icon
2/13/2026Smartleaf Asset Management LLC1,388$0.11M0.0%+1,234.6%0.001%Search for SEC Filing on Google Icon
2/13/2026Bank of Nova Scotia4,189$0.33M0.0%+19.4%0.003%Search for SEC Filing on Google Icon
2/13/2026Exome Asset Management LLC116,515$9.22M4.4%-11.1%0.072%Search for SEC Filing on Google Icon
2/13/2026Rafferty Asset Management LLC73,983$5.85M0.0%-41.2%0.046%Search for SEC Filing on Google Icon
2/13/2026First Trust Advisors LP525,239$41.55M0.0%+598.2%0.324%Search for SEC Filing on Google Icon
2/13/2026Davern Capital Partners LP238,477$18.87M6.1%N/A0.147%Search for SEC Filing on Google Icon
2/13/2026Alyeska Investment Group L.P.481,711$38.11M0.1%+54.8%0.297%Search for SEC Filing on Google Icon
2/13/2026Charles Schwab Investment Management Inc.1,541,841$121.98M0.0%+1.4%0.952%Search for SEC Filing on Google Icon
2/13/2026Police & Firemen s Retirement System of New Jersey66,849$5.29M0.0%-3.6%0.041%Search for SEC Filing on Google Icon
2/13/2026Van ECK Associates Corp47,102$3.73M0.0%-57.9%0.029%Search for SEC Filing on Google Icon
2/13/2026Vontobel Holding Ltd.5,240$0.42M0.0%N/A0.003%Search for SEC Filing on Google Icon
2/13/2026UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC1,388,567$109.85M0.0%+20.3%0.857%Search for SEC Filing on Google Icon
2/13/2026Rhenman & Partners Asset Management AB158,500$12.54M1.2%-48.9%0.098%Search for SEC Filing on Google Icon
2/12/2026Advisors Asset Management Inc.2,835$0.22M0.0%-48.0%0.002%Search for SEC Filing on Google Icon
2/12/2026Federation des caisses Desjardins du Quebec12,553$0.99M0.0%N/A0.008%Search for SEC Filing on Google Icon
2/12/2026HRT Financial LP22,928$1.81M0.0%N/A0.014%Search for SEC Filing on Google Icon
2/12/2026Brooklyn Investment Group4,669$0.37M0.0%N/A0.003%Search for SEC Filing on Google Icon
2/12/2026Orion Porfolio Solutions LLC23,574$1.87M0.0%+136.6%0.015%Search for SEC Filing on Google Icon
2/12/2026MetLife Investment Management LLC9,674$0.77M0.0%+2.6%0.006%Search for SEC Filing on Google Icon
2/12/2026Commonwealth Equity Services LLC11,806$0.93M0.0%-11.6%0.007%Search for SEC Filing on Google Icon
2/12/2026State Board of Administration of Florida Retirement System135,878$10.75M0.0%-5.3%0.084%Search for SEC Filing on Google Icon
2/12/2026Renaissance Technologies LLC223,607$17.69M0.0%-54.1%0.138%Search for SEC Filing on Google Icon
2/12/2026Dimensional Fund Advisors LP176,035$13.93M0.0%+317.0%0.109%Search for SEC Filing on Google Icon
2/12/2026Ensign Peak Advisors Inc53,664$4.25M0.0%+94.5%0.033%Search for SEC Filing on Google Icon
2/12/2026AlphaCentric Advisors LLC18,523$1.47M1.4%N/A0.011%Search for SEC Filing on Google Icon
2/12/2026Marex Group plc3,524$0.28M0.0%-47.6%0.002%Search for SEC Filing on Google Icon
2/12/2026Informed Momentum Co LLC53,914$4.27M0.5%-1.9%0.033%Search for SEC Filing on Google Icon
Data available starting January 2016

See Full Table
Ionis Pharmaceuticals logo
Ionis Pharmaceuticals, Inc. discovers and develops RNA-targeted therapeutics in the United States. The company offers SPINRAZA for spinal muscular atrophy (SMA) in pediatric and adult patients; TEGSEDI, an antisense injection for the treatment of polyneuropathy caused by hereditary transthyretin amyloidosis in adults; and WAYLIVRA, an antisense medicine for treatment for familial chylomicronemia syndrome (FCS) and familial partial lipodystrophy. It also develops medicines for various indications that are in phase 3 study, including Eplontersen as a monthly self-administered subcutaneous injection to treat all types of ATTR; Olezarsen for patients with FCS and severe hypertriglyceridemia (SHTG); Donidalorsen for patients with hereditary angioedema; ION363 for patients with amyotrophic lateral sclerosis; Tofersen to inhibit the production of superoxide dismutase 1; Pelacarsen for patients with established cardiovascular disease and elevated lipoprotein(a); and Bepirovirsen to inhibit the production of viral proteins associated with hepatitis B virus. In addition, the company develops IONIS-FB-LRx to inhibit the production of complement factor B and the alternative complement pathway; and ION224 to reduce the production of diacylglycerol acyltransferase 2. It has a strategic collaboration with Biogen for the treatment of neurological disorders; and collaboration and license agreement with Metagenomi, Inc, AstraZeneca, Bayer AG, GlaxoSmithKline plc, Novartis, Roche, Swedish Orphan Biovitrum AB, and PTC Therapeutics. The company was incorporated in 1989 and is based in Carlsbad, California.
Read More on Ionis Pharmaceuticals

Today's Range

Now: $70.99
Low: $70.50
High: $72.59

50 Day Range

MA: $79.58
Low: $70.99
High: $86.50

52 Week Range

Now: $70.99
Low: $23.95
High: $86.74

Volume

2,920,608 shs

Average Volume

2,536,478 shs

Market Capitalization

$11.73 billion

P/E Ratio

N/A

Dividend Yield

N/A

Beta

0.31

Who are the company insiders with the largest holdings of Ionis Pharmaceuticals?

Ionis Pharmaceuticals' top insider investors include:
  1. Brett P Monia (CEO)
  2. Elizabeth L Hougen (EVP)
  3. Joseph H Wender (Director)
  4. Elizabeth L Hougen (CFO)
  5. C Frank Bennett (EVP)
  6. Richard S Geary (EVP)
  7. B Lynne Parshall (Director)
  8. Patrick R O'neil (EVP)
  9. Eugene Schneider (EVP)
  10. Brian Birchler (EVP)
  11. Michael R Hayden (Director)
  12. Eric Swayze (EVP)
  13. Shannon L Devers (EVP)
  14. Joseph Baroldi (EVP)
  15. Allene M Diaz (Director)
  16. Kyle Jenne (EVP)
  17. Joseph Klein III (Director)
  18. Holly B Kordasiewicz (EVP)
Learn More about top insider investors at Ionis Pharmaceuticals.

Who are the major institutional investors of Ionis Pharmaceuticals?

Ionis Pharmaceuticals' top institutional shareholders include:
  1. Capital World Investors — 11.09%
  2. Vanguard Group Inc. — 10.15%
  3. T. Rowe Price Investment Management Inc. — 5.62%
  4. T. Rowe Price Investment Management Inc. — 3.57%
  5. Geode Capital Management LLC — 1.94%
  6. Price T Rowe Associates Inc. MD — 1.84%
Learn More about top institutional investors of Ionis Pharmaceuticals stock.

Which institutional investors are selling Ionis Pharmaceuticals stock?

In the last quarter, IONS stock was sold by these institutional investors:
  1. T. Rowe Price Investment Management Inc.
  2. T. Rowe Price Investment Management Inc.
  3. Adage Capital Partners GP L.L.C.
  4. Marshall Wace LLP
  5. Deutsche Bank AG
  6. Zurcher Kantonalbank Zurich Cantonalbank
  7. Tweedy Browne Co LLC
  8. Groupama Asset Managment
In the previous year, company insiders that have sold Ionis Pharmaceuticals company stock include:
  1. Brett P Monia (CEO)
  2. Elizabeth L Hougen (EVP)
  3. Joseph H Wender (Director)
  4. Elizabeth L Hougen (CFO)
  5. C Frank Bennett (EVP)
  6. Richard S Geary (EVP)
  7. B Lynne Parshall (Director)
  8. Patrick R O'neil (EVP)
  9. Eugene Schneider (EVP)
  10. Brian Birchler (EVP)
  11. Michael R Hayden (Director)
  12. Eric Swayze (EVP)
  13. Shannon L Devers (EVP)
  14. Joseph Baroldi (EVP)
Learn More investors selling Ionis Pharmaceuticals stock.

Which institutional investors are buying Ionis Pharmaceuticals stock?

During the last quarter, IONS stock was purchased by institutional investors including:
  1. Capital World Investors
  2. Franklin Resources Inc.
  3. Baker BROS. Advisors LP
  4. Eventide Asset Management LLC
  5. GW&K Investment Management LLC
  6. First Trust Advisors LP
  7. Arrowstreet Capital Limited Partnership
  8. Norges Bank