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IONS Insider Trading

Insider Ownership Percentage: 2.71%
Insider Buying (Last 12 Months): $477,900.00
Insider Selling (Last 12 Months): $89,921,385.44

Ionis Pharmaceuticals Insider Trading History Chart

This chart shows the insider buying and selling history at Ionis Pharmaceuticals by year and by quarter.

Skip ChartChart Data in Insider Trading History Table

Ionis Pharmaceuticals Share Price & Price History

Current Price: $84.59
Price Change: ▲ Price Increase of +1.52 (1.83%)
As of 02/3/2026 05:00 PM ET

This chart shows the closing price history over time for IONS up to the past year.

Skip Chart and Table DataPrice Data in Insider Trading History Table
Days: 30 | 90 | 365

Ionis Pharmaceuticals Insider Trading History

Transaction DateInsider NameTitleBuy/SellNumber of SharesAverage Share PriceTotal TransactionShares Held After TransactionDetails
1/30/2026Brett P. MoniaCEOSell62,970$82.72$5,208,878.40283,927View SEC Filing Icon  
1/30/2026Brian BirchlerEVPSell6,179$83.03$513,042.3766,247View SEC Filing Icon  
1/30/2026C. Frank BennettEVPSell5,885$82.95$488,160.75100,293View SEC Filing Icon  
1/30/2026C. Frank BennettEVPSell5,885$82.95$488,160.75100,293View SEC Filing Icon  
1/30/2026Elizabeth L. HougenEVPSell6,988$83.24$581,681.12132,881View SEC Filing Icon  
1/30/2026Eric SwayzeEVPSell6,179$82.93$512,424.4747,747View SEC Filing Icon  
1/30/2026Eugene SchneiderEVPSell6,179$83.45$515,637.5569,702View SEC Filing Icon  
1/30/2026Patrick R. O'NeilEVPSell6,179$83.53$516,131.8771,983View SEC Filing Icon  
1/30/2026Patrick R. O'NeilEVPSell6,179$83.53$516,131.8771,983View SEC Filing Icon  
1/22/2026Shannon L. DeversEVPSell3,977$81.34$323,489.1822,541View SEC Filing Icon  
1/16/2026Brett P. MoniaCEOSell44,034$74.82$3,294,623.88224,683View SEC Filing Icon  
1/16/2026Brian BirchlerEVPSell8,480$75.11$636,932.8060,435View SEC Filing Icon  
1/16/2026C. Frank BennettEVPSell8,977$75.15$674,621.5594,757View SEC Filing Icon  
1/16/2026Elizabeth L. HougenEVPSell12,922$75.22$971,992.84126,307View SEC Filing Icon  
1/16/2026Eric SwayzeEVPSell9,884$75.34$744,660.5641,935View SEC Filing Icon  
1/16/2026Eric SwayzeEVPSell49$75.97$3,722.53318View SEC Filing Icon  
1/16/2026Eugene SchneiderEVPSell9,302$75.59$703,138.1863,890View SEC Filing Icon  
1/16/2026Holly B. KordasiewiczEVPSell4,141$75.66$313,308.0614,718View SEC Filing Icon  
1/16/2026Kyle JenneEVPSell1,823$75.96$138,475.0816,389View SEC Filing Icon  
1/16/2026Patrick R. O'NeilEVPSell9,191$75.84$697,045.4466,171View SEC Filing Icon  
1/16/2026Shannon L. DeversEVPSell8,353$75.95$634,410.3526,518View SEC Filing Icon  
1/7/2026Shannon L. DeversEVPSell44,199$85.08$3,760,450.9217,494View SEC Filing Icon  
1/2/2026Eric SwayzeEVPSell23,463$79.12$1,856,392.5630,453View SEC Filing Icon  
12/1/2025Joseph H. WenderDirectorSell28,000$80.82$2,262,960.0036,035View SEC Filing Icon  
11/25/2025Shannon L. DeversEVPSell16,777$80.91$1,357,427.0717,494View SEC Filing Icon  
11/6/2025Brian BirchlerEVPSell8,000$76.17$609,360.0048,826View SEC Filing Icon  
11/6/2025Richard S. GearyEVPSell33,038$75.72$2,501,637.3659,657View SEC Filing Icon  
11/5/2025Richard S. GearyEVPSell1,601$75.01$120,091.0159,657View SEC Filing Icon  
11/3/2025Richard S. GearyEVPSell1,680$75.05$126,084.0059,657View SEC Filing Icon  
10/31/2025Joseph H. WenderDirectorSell11,200$75.16$841,792.0064,035View SEC Filing Icon  
10/31/2025Richard S. GearyEVPSell89,249$75.11$6,703,492.3959,657View SEC Filing Icon  
10/30/2025Joseph H. WenderDirectorSell16,800$73.26$1,230,768.0075,235View SEC Filing Icon  
10/16/2025Eric SwayzeEVPSell53$73.62$3,901.86256View SEC Filing Icon  
10/16/2025Shannon L. DeversEVPSell1,263$73.62$92,982.0617,494View SEC Filing Icon  
10/15/2025B. Lynne Parshall, Esq.DirectorSell5,000$71.74$358,700.0061,344View SEC Filing Icon  
10/15/2025Brian BirchlerEVPSell12,425$72.23$897,457.7556,826View SEC Filing Icon  
10/15/2025Shannon L. DeversEVPSell6,000$72.94$437,640.0015,937View SEC Filing Icon  
10/14/2025Brian BirchlerEVPSell11,475$72.03$826,544.2556,826View SEC Filing Icon  
10/6/2025Brett P. MoniaCEOSell437$69.26$30,266.62179,572View SEC Filing Icon  
10/6/2025Eric SwayzeEVPSell6,849$69.02$472,717.9830,453View SEC Filing Icon  
10/6/2025Patrick R. O'NeilEVPSell13,441$69.74$937,375.3453,889View SEC Filing Icon  
10/2/2025Eric SwayzeEVPSell12,972$66.23$859,135.5637,302View SEC Filing Icon  
10/2/2025Patrick R. O'NeilEVPSell64,664$67.69$4,377,106.1657,130View SEC Filing Icon  
10/1/2025Eric SwayzeEVPSell14,142$66.09$934,644.7837,302View SEC Filing Icon  
10/1/2025Joseph H. WenderDirectorSell16,800$65.50$1,100,400.0092,035View SEC Filing Icon  
9/30/2025Elizabeth L. HougenEVPSell49,800$65.26$3,249,948.00110,500View SEC Filing Icon  
9/30/2025Patrick R. O'NeilEVPSell14,827$64.68$959,010.3657,130View SEC Filing Icon  
9/30/2025Richard S. GearyEVPSell57,900$65.24$3,777,396.0079,657View SEC Filing Icon  
9/29/2025Patrick R. O'NeilEVPSell10,473$64.54$675,927.4257,130View SEC Filing Icon  
9/12/2025Patrick R. O'NeilEVPSell1,700$64.58$109,786.0057,130View SEC Filing Icon  
9/9/2025Patrick R. O'NeilEVPSell21,000$64.56$1,355,760.0057,130View SEC Filing Icon  
9/5/2025C. Frank BennettEVPSell6,000$59.60$357,600.0082,679View SEC Filing Icon  
9/3/2025Brett P. MoniaCEOSell203,814$60.32$12,294,060.48180,009View SEC Filing Icon  
9/3/2025C. Frank BennettEVPSell33,909$60.62$2,055,563.58101,570View SEC Filing Icon  
9/3/2025Eugene SchneiderEVPSell19,658$60.81$1,195,402.9851,507View SEC Filing Icon  
9/3/2025Joseph H. WenderDirectorSell11,200$60.14$673,568.00108,835View SEC Filing Icon  
9/3/2025Patrick R. O'NeilEVPSell76,850$60.97$4,685,544.505,655View SEC Filing Icon  
9/3/2025Shannon L. DeversEVPSell3,162$61.02$192,945.2415,009View SEC Filing Icon  
9/2/2025B. Lynne Parshall, Esq.DirectorSell20,000$50.91$1,018,200.0066,344View SEC Filing Icon  
9/2/2025C. Frank BennettEVPSell5,000$49.14$245,700.0088,679View SEC Filing Icon  
9/2/2025Eric SwayzeEVPSell11,130$49.67$552,827.1037,302View SEC Filing Icon  
9/2/2025Joseph H. WenderDirectorSell16,800$55.87$938,616.00120,035View SEC Filing Icon  
9/2/2025Patrick R. O'NeilEVPSell13,050$54.51$711,355.5057,130View SEC Filing Icon  
9/2/2025Richard S. GearyEVPSell10,000$50.37$503,700.0079,657View SEC Filing Icon  
8/22/2025Allene M. DiazDirectorSell1,427$42.53$60,690.3118,368View SEC Filing Icon  
8/18/2025C. Frank BennettEVPSell10,000$43.98$439,800.0093,466View SEC Filing Icon  
8/6/2025B. Lynne Parshall, Esq.DirectorSell5,000$41.93$209,650.0086,344View SEC Filing Icon  
8/5/2025Richard S. GearyEVPSell10,000$42.86$428,600.0089,492View SEC Filing Icon  
8/4/2025Eugene SchneiderEVPSell9,549$42.80$408,697.2051,507View SEC Filing Icon  
7/30/2025Brett P. MoniaCEOSell2,432$45.00$109,440.00179,820View SEC Filing Icon  
7/11/2025Brett P. MoniaCEOSell1,160$41.74$48,418.40179,820View SEC Filing Icon  
5/1/2025Michael R. HaydenDirectorBuy15,000$31.86$477,900.0050,219View SEC Filing Icon  
4/16/2025Brian BirchlerEVPSell680$28.37$19,291.6056,660View SEC Filing Icon  
3/11/2025Brett P. MoniaCEOSell140$32.32$4,524.80180,980View SEC Filing Icon  
2/20/2025Patrick R. O'NeilEVPSell1,207$32.35$39,046.4556,245View SEC Filing Icon  
2/4/2025Brett P. MoniaCEOSell38,843$31.65$1,229,380.95180,683View SEC Filing Icon  
2/4/2025Patrick R. O'NeilEVPSell6,165$31.62$194,937.3057,452View SEC Filing Icon  
1/31/2025Brett P. MoniaCEOSell13,242$32.45$429,702.90219,526View SEC Filing Icon  
1/31/2025Elizabeth L. HougenCFOSell1,523$32.44$49,406.12110,500View SEC Filing Icon  
1/31/2025Eric SwayzeEVPSell1,367$32.31$44,167.7748,017View SEC Filing Icon  
1/16/2025Brett P. MoniaCEOSell33,445$32.63$1,091,310.35207,396View SEC Filing Icon  
1/16/2025Elizabeth L. HougenCFOSell8,870$32.81$291,024.70107,885View SEC Filing Icon  
1/16/2025Eric SwayzeEVPSell7,154$32.84$234,937.3645,670View SEC Filing Icon  
12/23/2024Michael R. HaydenDirectorBuy5,000$36.22$181,100.0035,219View SEC Filing Icon  
11/12/2024Brett P. MoniaCEOSell6,630$38.05$252,271.50167,393View SEC Filing Icon  
11/12/2024Eric SwayzeEVPSell1,194$37.92$45,276.4833,713View SEC Filing Icon  
10/16/2024Eric SwayzeEVPSell53$38.31$2,030.43157View SEC Filing Icon  
8/28/2024Richard S. GearyEVPSell320$49.16$15,731.2085,154View SEC Filing Icon  
8/5/2024Richard S. GearyEVPSell2,430$48.00$116,640.0085,508View SEC Filing Icon  
7/16/2024Joseph Klein, IIIDirectorSell12,000$50.00$600,000.0016,346View SEC Filing Icon  
5/3/2024Joseph Klein, IIIDirectorSell6,000$42.71$256,260.0016,346View SEC Filing Icon  
4/16/2024Joseph BaroldiEVPSell4,006$41.60$166,649.6019,631View SEC Filing Icon  
2/16/2024Brett P. MoniaCEOSell387$44.49$17,217.63173,751View SEC Filing Icon  
2/2/2024Brett P. MoniaCEOSell23,501$49.37$1,160,244.37174,138View SEC Filing Icon  
2/2/2024Elizabeth L. HougenCFOSell2,125$49.54$105,272.5092,905View SEC Filing Icon  
2/2/2024Eric SwayzeEVPSell1,907$49.56$94,510.9234,324View SEC Filing Icon  
1/31/2024Eric SwayzeEVPSell10,773$52.00$560,196.0032,516View SEC Filing Icon  
1/25/2024Brett P. MoniaCEOSell2,285$51.75$118,248.75151,851View SEC Filing Icon  
1/25/2024Patrick R. O'NeilEVPSell6,450$51.75$333,787.5046,802View SEC Filing Icon  
1/17/2024Brett P. MoniaCEOSell32,059$50.42$1,616,414.78154,136View SEC Filing Icon  
1/17/2024Elizabeth L. HougenCFOSell8,683$50.42$437,796.8690,890View SEC Filing Icon  
1/17/2024Onaiza J. Cadoret-ManierEVPSell5,564$50.42$280,536.8833,810View SEC Filing Icon  
1/12/2024Eugene SchneiderEVPSell8,000$53.50$428,000.0038,170View SEC Filing Icon  
12/28/2023B. Lynne Parshall, Esq.DirectorSell42,525$50.19$2,134,329.7582,588View SEC Filing Icon  
12/26/2023B. Lynne Parshall, Esq.DirectorSell25,113$51.46$1,292,314.9882,588View SEC Filing Icon  
12/26/2023Patrick R. O'NeilEVPSell20,825$51.46$1,071,654.5040,355View SEC Filing Icon  
12/21/2023Brett P. MoniaCEOSell17,500$49.29$862,575.00118,111View SEC Filing Icon  
12/20/2023C. Frank BennettEVPSell6,500$49.64$322,660.0065,754View SEC Filing Icon  
12/14/2023Brett P. MoniaCEOSell24,000$49.58$1,189,920.00118,111View SEC Filing Icon  
11/15/2023Joseph Klein, IIIDirectorSell2,000$50.00$100,000.0016,346View SEC Filing Icon  
10/17/2023Eric SwayzeEVPSell52$47.95$2,493.4073View SEC Filing Icon  
10/12/2023Brett P. MoniaCEOSell3,770$46.00$173,420.00118,111View SEC Filing Icon  
9/28/2023C. Frank BennettEVPSell4,460$46.50$207,390.0065,754View SEC Filing Icon  
9/26/2023B. Lynne Parshall, Esq.DirectorSell10,000$45.13$451,300.0082,588View SEC Filing Icon  
8/1/2023Allene M. DiazDirectorSell657$41.05$26,969.8512,676View SEC Filing Icon  
7/18/2023Joseph Klein, IIIDirectorSell3,555$42.00$149,310.0020,346View SEC Filing Icon  
7/7/2023Brett P. MoniaCEOSell18,650$42.25$787,962.50121,724View SEC Filing Icon  
5/24/2023Patrick R. O'NeilEVPSell1,527$41.70$63,675.9040,355View SEC Filing Icon  
5/22/2023Brett P. MoniaCEOSell4,931$40.14$197,930.34140,374View SEC Filing Icon  
4/18/2023Brian BirchlerEVPSell672$36.50$24,528.0036,528View SEC Filing Icon  
2/6/2023Brett P. MoniaCEOSell24,651$40.69$1,003,049.19145,305View SEC Filing Icon  
2/6/2023Elizabeth L. HougenCFOSell2,079$40.59$84,386.6175,496View SEC Filing Icon  
2/6/2023Eric SwayzeEVPSell1,815$40.79$74,033.8531,941View SEC Filing Icon  
See Full Table

SEC Filings (Institutional Ownership Changes) for Ionis Pharmaceuticals (NASDAQ:IONS)

93.86% of Ionis Pharmaceuticals stock is owned by institutions. Institutional ownership can be a sign of analyst confidence in the fundamentals of the stock.

Institutional Buying and Selling by Quarter

This chart shows the instiutional buying and selling at IONS by year and by quarter.

Skip Institutional Buying and Selling Chart and Table DataRead Chart Data in Institutional Trading History Table

Ionis Pharmaceuticals Institutional Trading History

Reporting DateHedge FundShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
2/3/2026Crossmark Global Holdings Inc.3,102$0.25M0.0%N/A0.002%Search for SEC Filing on Google Icon
2/3/2026International Assets Investment Management LLC1,217$96K0.0%-85.2%0.001%Search for SEC Filing on Google Icon
2/3/2026Swedbank AB27,253$2.16M0.0%N/A0.017%Search for SEC Filing on Google Icon
2/3/2026Mitsubishi UFJ Asset Management Co. Ltd.2,750$0.22M0.0%-49.1%0.002%Search for SEC Filing on Google Icon
2/3/2026Privium Fund Management B.V.240,824$19.05M3.5%-3.2%0.149%Search for SEC Filing on Google Icon
2/3/2026Tweedy Browne Co LLC2,464,930$195M15.7%-15.0%1.522%Search for SEC Filing on Google Icon
2/2/2026Kornitzer Capital Management Inc. KS29,105$2.30M0.0%N/A0.018%Search for SEC Filing on Google Icon
2/2/2026Fifth Third Bancorp7,888$0.62M0.0%-39.1%0.005%Search for SEC Filing on Google Icon
1/30/2026Laurel Wealth Advisors LLC600$47K0.0%N/A0.000%Search for SEC Filing on Google Icon
1/30/2026State of New Jersey Common Pension Fund D54,783$4.33M0.0%-8.4%0.034%Search for SEC Filing on Google Icon
1/30/2026M&T Bank Corp8,150$0.64M0.0%+35.6%0.005%Search for SEC Filing on Google Icon
1/29/2026Comerica Bank3,997$0.32M0.0%+82.8%0.002%Search for SEC Filing on Google Icon
1/29/2026Pictet Asset Management Holding SA1,418,491$112.48M0.1%+1.8%0.876%Search for SEC Filing on Google Icon
1/29/2026UBS Group AG1,045,041$82.67M0.0%-1.8%0.645%Search for SEC Filing on Google Icon
1/29/2026Sanctuary Advisors LLC4,502$0.36M0.0%+23.8%0.003%Search for SEC Filing on Google Icon
1/29/2026Vanguard Group Inc.16,440,459$1.30B0.0%-0.3%10.150%Search for SEC Filing on Google Icon
1/29/2026China Universal Asset Management Co. Ltd.42,394$3.35M0.3%+51.7%0.026%Search for SEC Filing on Google Icon
1/28/2026Arizona State Retirement System42,421$3.36M0.0%-5.2%0.026%Search for SEC Filing on Google Icon
1/28/2026Teacher Retirement System of Texas422,899$33.46M0.1%-10.8%0.261%Search for SEC Filing on Google Icon
1/28/2026West Michigan Advisors LLC38,413$3.04M0.7%N/A0.024%Search for SEC Filing on Google Icon
1/28/2026HB Wealth Management LLC2,922$0.23M0.0%N/A0.002%Search for SEC Filing on Google Icon
1/28/2026M&T Bank Corp88,510$7M0.0%+1,372.7%0.055%Search for SEC Filing on Google Icon
1/27/2026Zurcher Kantonalbank Zurich Cantonalbank 48,921$3.87M0.0%-91.0%0.030%Search for SEC Filing on Google Icon
1/27/2026Bayforest Capital Ltd1,091$86K0.1%+608.4%0.001%Search for SEC Filing on Google Icon
1/27/2026Friedenthal Financial13,115$1.04M0.5%N/A0.008%Search for SEC Filing on Google Icon
1/27/2026GF Fund Management CO. LTD.3,183$0.25M0.0%-7.2%0.002%Search for SEC Filing on Google Icon
1/26/2026Mirae Asset Global Investments Co. Ltd.8,266$0.65M0.0%+34.1%0.005%Search for SEC Filing on Google Icon
1/26/2026CWM LLC5,049$0.40M0.0%+102.9%0.003%Search for SEC Filing on Google Icon
1/26/2026KBC Group NV9,052$0.72M0.0%+92.6%0.006%Search for SEC Filing on Google Icon
1/26/2026BLB&B Advisors LLC61,520$4.87M0.2%-48.1%0.038%Search for SEC Filing on Google Icon
1/23/2026Farther Finance Advisors LLC1,199$95K0.0%+111.8%0.001%Search for SEC Filing on Google Icon
1/23/2026Assetmark Inc.8,650$0.68M0.0%+11,433.3%0.005%Search for SEC Filing on Google Icon
1/23/2026KOM Wealth Management Group LLC2,695$0.21M0.2%N/A0.002%Search for SEC Filing on Google Icon
1/23/2026Stanley Laman Group Ltd.36,512$2.89M0.4%+2.1%0.023%Search for SEC Filing on Google Icon
1/23/2026Sumitomo Mitsui Trust Group Inc.93,751$7.42M0.0%-18.3%0.058%Search for SEC Filing on Google Icon
1/22/2026Massachusetts Financial Services Co. MA812,747$64.30M0.0%-5.8%0.502%Search for SEC Filing on Google Icon
1/22/2026Venturi Wealth Management LLC3,061$0.24M0.0%N/A0.002%Search for SEC Filing on Google Icon
1/16/2026Aberdeen Group plc28,926$2.29M0.0%-67.1%0.018%Search for SEC Filing on Google Icon
1/16/2026Tema Etfs LLC8,557$0.68M0.1%-30.5%0.005%Search for SEC Filing on Google Icon
1/15/2026J. Safra Sarasin Holding AG17,404$1.38M0.0%N/A0.011%Search for SEC Filing on Google Icon
1/14/2026Mitchell & Pahl Private Wealth LLC3,379$0.27M0.1%-5.4%0.002%Search for SEC Filing on Google Icon
1/14/2026Sicart Associates LLC163,557$12.94M3.4%-0.5%0.101%Search for SEC Filing on Google Icon
1/14/2026Exchange Traded Concepts LLC21,094$1.67M0.0%+16.7%0.013%Search for SEC Filing on Google Icon
1/13/2026Norden Group LLC2,935$0.23M0.0%N/A0.002%Search for SEC Filing on Google Icon
1/12/2026DAVENPORT & Co LLC217,897$17.24M0.1%+248.3%0.135%Search for SEC Filing on Google Icon
1/12/2026Avanza Fonder AB3,596$0.28M0.0%N/A0.002%Search for SEC Filing on Google Icon
1/9/2026SG Americas Securities LLC33,409$2.64M0.0%+548.7%0.021%Search for SEC Filing on Google Icon
1/9/2026Assenagon Asset Management S.A.29,316$2.32M0.0%-90.6%0.018%Search for SEC Filing on Google Icon
1/8/2026Wealth Enhancement Advisory Services LLC8,256$0.67M0.0%+11.0%0.005%Search for SEC Filing on Google Icon
1/8/2026Wedmont Private Capital5,536$0.46M0.0%+3.2%0.003%Search for SEC Filing on Google Icon
1/7/2026Significant Wealth Partners LLC6,764$0.54M0.6%-54.8%0.004%Search for SEC Filing on Google Icon
1/7/2026Everhart Financial Group Inc.3,465$0.27M0.0%N/A0.002%Search for SEC Filing on Google Icon
1/5/2026Park Avenue Securities LLC3,571$0.28M0.0%N/A0.002%Search for SEC Filing on Google Icon
1/5/2026GAMMA Investing LLC1,733$0.14M0.0%+29.2%0.001%Search for SEC Filing on Google Icon
12/15/2025Hudson Bay Capital Management LP515,000$33.69M0.1%-31.3%0.318%Search for SEC Filing on Google Icon
12/2/2025Swiss Life Asset Management Ltd6,827$0.45M0.0%N/A0.004%Search for SEC Filing on Google Icon
12/1/2025Groupama Asset Managment1,061,777$69.46M0.2%-8.5%0.656%Search for SEC Filing on Google Icon
11/25/2025BlueCrest Capital Management Ltd23,370$1.53M0.0%N/A0.014%Search for SEC Filing on Google Icon
11/21/2025Alpine Global Management LLC55,900$3.66M0.6%+119.8%0.035%Search for SEC Filing on Google Icon
11/20/2025Tweedy Browne Co LLC2,901,216$189.80M16.5%+0.3%1.791%Search for SEC Filing on Google Icon
11/19/2025Coldstream Capital Management Inc.4,479$0.29M0.0%N/A0.003%Search for SEC Filing on Google Icon
11/19/2025Danske Bank A S1,400$92K0.0%N/A0.001%Search for SEC Filing on Google Icon
11/18/2025Raab & Moskowitz Asset Management LLC3,115$0.20M0.0%N/A0.002%Search for SEC Filing on Google Icon
11/17/2025NewEdge Advisors LLC4,822$0.32M0.0%+2,360.2%0.003%Search for SEC Filing on Google Icon
11/17/2025CANADA LIFE ASSURANCE Co46,128$2.96M0.0%-0.8%0.028%Search for SEC Filing on Google Icon
11/17/2025PharVision Advisers LLC3,587$0.24M0.1%N/A0.002%Search for SEC Filing on Google Icon
11/17/2025Dark Forest Capital Management LP46,092$3.02M0.1%N/A0.028%Search for SEC Filing on Google Icon
11/17/2025Alyeska Investment Group L.P.311,258$20.36M0.1%+95.7%0.192%Search for SEC Filing on Google Icon
11/17/2025Voleon Capital Management LP3,060$0.20M0.0%N/A0.002%Search for SEC Filing on Google Icon
11/17/2025Voloridge Investment Management LLC803,047$52.54M0.2%-6.0%0.496%Search for SEC Filing on Google Icon
11/17/2025Wexford Capital LP1,192$78K0.0%-74.9%0.001%Search for SEC Filing on Google Icon
11/17/2025Verition Fund Management LLC37,196$2.43M0.0%-84.0%0.023%Search for SEC Filing on Google Icon
11/17/2025Vestal Point Capital LP1,075,000$70.33M3.2%+115.0%0.664%Search for SEC Filing on Google Icon
11/17/2025Polar Capital Holdings Plc1,033,622$67.62M0.3%+3.4%0.638%Search for SEC Filing on Google Icon
11/17/2025Quarry LP588$38K0.0%N/A0.000%Search for SEC Filing on Google Icon
11/17/2025Prelude Capital Management LLC37,293$2.44M0.2%-5.4%0.023%Search for SEC Filing on Google Icon
11/17/2025Public Employees Retirement System of Ohio48,545$3.18M0.0%+0.6%0.030%Search for SEC Filing on Google Icon
11/17/2025Northern Trust Corp844,943$55.28M0.0%+3.8%0.522%Search for SEC Filing on Google Icon
11/17/2025Northwestern Mutual Wealth Management Co.12,782$0.84M0.0%+4.4%0.008%Search for SEC Filing on Google Icon
11/17/2025Mariner LLC24,227$1.59M0.0%-34.4%0.015%Search for SEC Filing on Google Icon
11/17/2025Mercer Global Advisors Inc. ADV3,747$0.25M0.0%N/A0.002%Search for SEC Filing on Google Icon
11/17/2025Millennium Management LLC779,570$51M0.0%-70.6%0.481%Search for SEC Filing on Google Icon
11/17/2025MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.6,431$0.41M0.0%-9.1%0.004%Search for SEC Filing on Google Icon
11/17/2025Jain Global LLC225,739$14.77M0.1%+3,037.4%0.139%Search for SEC Filing on Google Icon
11/17/2025Gotham Asset Management LLC32,152$2.10M0.0%+125.2%0.020%Search for SEC Filing on Google Icon
11/17/2025Farallon Capital Management LLC4,800$0.31M0.0%N/A0.003%Search for SEC Filing on Google Icon
11/17/2025Fred Alger Management LLC42,401$2.77M0.0%+348.0%0.026%Search for SEC Filing on Google Icon
11/17/2025BlueCrest Capital Management Ltd23,370$1.53M0.0%N/A0.014%Search for SEC Filing on Google Icon
11/17/2025Brevan Howard Capital Management LP4,516$0.30M0.0%-86.2%0.003%Search for SEC Filing on Google Icon
11/17/2025Cinctive Capital Management LP173,819$11.37M0.5%N/A0.107%Search for SEC Filing on Google Icon
11/17/2025Baker BROS. Advisors LP566,798$37.08M0.3%N/A0.350%Search for SEC Filing on Google Icon
11/17/2025Bamco Inc. NY25,000$1.64M0.0%N/A0.015%Search for SEC Filing on Google Icon
11/17/2025California Public Employees Retirement System215,845$14.12M0.0%+6.9%0.133%Search for SEC Filing on Google Icon
11/17/2025Bank of Nova Scotia3,509$0.23M0.0%N/A0.002%Search for SEC Filing on Google Icon
11/17/2025Boone Capital Management LLC417,833$27.34M9.0%N/A0.258%Search for SEC Filing on Google Icon
11/17/2025Aquatic Capital Management LLC159,045$10.41M0.2%+0.6%0.098%Search for SEC Filing on Google Icon
11/17/2025Algert Global LLC252,281$16.50M0.3%+562.3%0.156%Search for SEC Filing on Google Icon
11/17/2025Alliancebernstein L.P.54,262$3.55M0.0%+4.2%0.034%Search for SEC Filing on Google Icon
11/14/2025Schonfeld Strategic Advisors LLC200,839$13.14M0.1%-55.3%0.124%Search for SEC Filing on Google Icon
11/14/2025Creative Planning51,474$3.37M0.0%-3.4%0.032%Search for SEC Filing on Google Icon
Data available starting January 2016

See Full Table
Ionis Pharmaceuticals logo
Ionis Pharmaceuticals, Inc. discovers and develops RNA-targeted therapeutics in the United States. The company offers SPINRAZA for spinal muscular atrophy (SMA) in pediatric and adult patients; TEGSEDI, an antisense injection for the treatment of polyneuropathy caused by hereditary transthyretin amyloidosis in adults; and WAYLIVRA, an antisense medicine for treatment for familial chylomicronemia syndrome (FCS) and familial partial lipodystrophy. It also develops medicines for various indications that are in phase 3 study, including Eplontersen as a monthly self-administered subcutaneous injection to treat all types of ATTR; Olezarsen for patients with FCS and severe hypertriglyceridemia (SHTG); Donidalorsen for patients with hereditary angioedema; ION363 for patients with amyotrophic lateral sclerosis; Tofersen to inhibit the production of superoxide dismutase 1; Pelacarsen for patients with established cardiovascular disease and elevated lipoprotein(a); and Bepirovirsen to inhibit the production of viral proteins associated with hepatitis B virus. In addition, the company develops IONIS-FB-LRx to inhibit the production of complement factor B and the alternative complement pathway; and ION224 to reduce the production of diacylglycerol acyltransferase 2. It has a strategic collaboration with Biogen for the treatment of neurological disorders; and collaboration and license agreement with Metagenomi, Inc, AstraZeneca, Bayer AG, GlaxoSmithKline plc, Novartis, Roche, Swedish Orphan Biovitrum AB, and PTC Therapeutics. The company was incorporated in 1989 and is based in Carlsbad, California.
Read More on Ionis Pharmaceuticals

Today's Range

Now: $84.59
Low: $83.00
High: $85.45

50 Day Range

MA: $80.42
Low: $76.33
High: $84.59

52 Week Range

Now: $84.59
Low: $23.95
High: $86.15

Volume

1,453,463 shs

Average Volume

2,349,598 shs

Market Capitalization

$13.70 billion

P/E Ratio

N/A

Dividend Yield

N/A

Beta

0.29

Who are the company insiders with the largest holdings of Ionis Pharmaceuticals?

Ionis Pharmaceuticals' top insider investors include:
  1. Brett P Monia (CEO)
  2. Elizabeth L Hougen (EVP)
  3. Joseph H Wender (Director)
  4. Elizabeth L Hougen (CFO)
  5. C Frank Bennett (EVP)
  6. Richard S Geary (EVP)
  7. B Lynne Parshall (Director)
  8. Patrick R O'neil (EVP)
  9. Eugene Schneider (EVP)
  10. Brian Birchler (EVP)
  11. Michael R Hayden (Director)
  12. Eric Swayze (EVP)
  13. Shannon L Devers (EVP)
  14. Joseph Baroldi (EVP)
  15. Allene M Diaz (Director)
  16. Kyle Jenne (EVP)
  17. Joseph Klein III (Director)
  18. Holly B Kordasiewicz (EVP)
Learn More about top insider investors at Ionis Pharmaceuticals.

Who are the major institutional investors of Ionis Pharmaceuticals?

Ionis Pharmaceuticals' top institutional shareholders include:
  1. Vanguard Group Inc. — 10.15%
  2. Pictet Asset Management Holding SA — 0.88%
  3. UBS Group AG — 0.65%
  4. Massachusetts Financial Services Co. MA — 0.50%
  5. Teacher Retirement System of Texas — 0.26%
  6. DAVENPORT & Co LLC — 0.13%
Learn More about top institutional investors of Ionis Pharmaceuticals stock.

Which institutional investors are selling Ionis Pharmaceuticals stock?

In the last quarter, IONS stock was sold by these institutional investors:
  1. Zurcher Kantonalbank Zurich Cantonalbank
  2. Assenagon Asset Management S.A.
  3. Aberdeen Group plc
  4. BLB&B Advisors LLC
  5. Teacher Retirement System of Texas
  6. Massachusetts Financial Services Co. MA
  7. Vanguard Group Inc.
  8. Sumitomo Mitsui Trust Group Inc.
In the previous year, company insiders that have sold Ionis Pharmaceuticals company stock include:
  1. Brett P Monia (CEO)
  2. Elizabeth L Hougen (EVP)
  3. Joseph H Wender (Director)
  4. Elizabeth L Hougen (CFO)
  5. C Frank Bennett (EVP)
  6. Richard S Geary (EVP)
  7. B Lynne Parshall (Director)
  8. Patrick R O'neil (EVP)
  9. Eugene Schneider (EVP)
  10. Brian Birchler (EVP)
  11. Michael R Hayden (Director)
  12. Eric Swayze (EVP)
  13. Shannon L Devers (EVP)
  14. Joseph Baroldi (EVP)
Learn More investors selling Ionis Pharmaceuticals stock.

Which institutional investors are buying Ionis Pharmaceuticals stock?

During the last quarter, IONS stock was purchased by institutional investors including:
  1. DAVENPORT & Co LLC
  2. M&T Bank Corp
  3. West Michigan Advisors LLC
  4. Kornitzer Capital Management Inc. KS
  5. SG Americas Securities LLC
  6. Pictet Asset Management Holding SA
  7. J. Safra Sarasin Holding AG
  8. China Universal Asset Management Co. Ltd.