KPTI Insider Trading

Insider Ownership Percentage: 10.24%
Insider Buying (Last 12 Months): $0.00
Insider Selling (Last 12 Months): $2,476,921.87

Karyopharm Therapeutics Insider Trading History Chart

This chart shows the insider buying and selling history at Karyopharm Therapeutics by year and by quarter.

Skip ChartChart Data in Insider Trading History Table

Karyopharm Therapeutics Share Price & Price History

Current Price: $3.52
Price Change: Price Decrease of -0.4 (-10.20%)
As of 03/30/2023 01:00 AM ET

This chart shows the closing price history over time for KPTI up to the past year.

Skip Chart and Table DataPrice Data in Insider Trading History Table
Days: 30 | 90 | 365

Karyopharm Therapeutics Insider Trading History

Transaction DateInsider NameTitleBuy/SellNumber of SharesAverage Share PriceTotal TransactionShares Held After TransactionDetails
3/6/2023Richard A PaulsonCEOSell3,506$3.16$11,078.96820,116View SEC Filing Icon  
3/1/2023Michael MasonCFOSell11,205$3.03$33,951.15245,361View SEC Filing Icon  
3/1/2023Richard A PaulsonCEOSell33,033$3.03$100,089.99823,622View SEC Filing Icon  
3/1/2023Sohanya Roshan ChengEVPSell11,239$3.03$34,054.17210,687View SEC Filing Icon  
3/1/2023Stephen MitchenerSVPSell6,357$3.03$19,261.71128,313View SEC Filing Icon  
2/15/2023Stuart PoultonEVPSell5,869$3.19$18,722.1164,131View SEC Filing Icon  
1/4/2023Richard A PaulsonCEOSell3,922$3.27$12,824.94608,605View SEC Filing Icon  
12/5/2022Richard A PaulsonCEOSell3,490$5.17$18,043.30612,527View SEC Filing Icon  
11/4/2022Richard A PaulsonCEOSell3,493$4.54$15,858.22616,017View SEC Filing Icon  
10/4/2022Richard A PaulsonCEOSell3,488$5.87$20,474.56619,510View SEC Filing Icon  
9/8/2022Richard A PaulsonCEOSell3,479$5.23$18,195.17622,998View SEC Filing Icon  
8/4/2022Richard A PaulsonCEOSell2,314$4.48$10,366.72626,477View SEC Filing Icon  
7/8/2022Richard A PaulsonCEOSell2,115$5.18$10,955.70628,791View SEC Filing Icon  
6/13/2022Sohanya Roshan ChengInsiderSell1,551$5.21$8,080.7189,949View SEC Filing Icon  
6/10/2022Deepika PakianathanDirectorSell1,307$6.00$7,842.0016,673View SEC Filing Icon  
6/8/2022Deepika PakianathanDirectorSell325,977$6.50$2,118,850.5018,731View SEC Filing Icon  
6/7/2022Richard A PaulsonCEOSell2,542$5.76$14,641.92630,906View SEC Filing Icon  
6/3/2022Michael MasonCFOSell601$6.04$3,630.04138,509View SEC Filing Icon  
2/7/2022Jatin ShahEVPSell1,704$9.86$16,801.44View SEC Filing Icon  
2/7/2022Michael KauffmanDirectorSell6,764$9.86$66,693.04View SEC Filing Icon  
2/7/2022Michael MasonCFOSell3,947$9.86$38,917.42View SEC Filing Icon  
2/7/2022Sharon ShachamInsiderSell6,707$9.86$66,131.02View SEC Filing Icon  
12/2/2021Stephen MitchenerSVPSell499$6.69$3,338.31View SEC Filing Icon  
5/7/2021Jatin ShahEVPBuy23,250$8.60$199,950.00View SEC Filing Icon  
5/6/2021Garen G. BohlinDirectorBuy4,000$7.82$31,280.004,000View SEC Filing Icon  
3/18/2021Sharon ShachamInsiderSell4,000$12.39$49,560.00920,152View SEC Filing Icon  
2/18/2021Jatin ShahEVPSell1,186$14.83$17,588.3851,791View SEC Filing Icon  
2/18/2021Sharon ShachamInsiderSell9,495$14.83$140,810.85776,452View SEC Filing Icon  
12/18/2020Mansoor Raza MirzaDirectorSell5,000$18.00$90,000.005,000View SEC Filing Icon  
12/7/2020Mansoor Raza MirzaDirectorSell20,000$16.07$321,400.0020,000View SEC Filing Icon  
12/1/2020Christopher Brett PrimianoEVPSell137,061$17.53$2,402,679.3382,647View SEC Filing Icon  
10/30/2020Tanya LewisEVPSell226$15.58$3,521.08765View SEC Filing Icon  
10/13/2020Christopher Brett PrimianoEVPSell39,271$16.86$662,109.0643,199View SEC Filing Icon  
10/12/2020Michael KauffmanCEOSell7,500$14.89$111,675.00555,122View SEC Filing Icon  
9/8/2020Christopher Brett PrimianoEVPSell10,054$14.98$150,608.9214,703View SEC Filing Icon  
8/26/2020John DemareeInsiderBuy7,500$14.54$109,050.007,500View SEC Filing Icon  
8/17/2020Michael KauffmanCEOSell1,477$15.00$22,155.00555,122View SEC Filing Icon  
7/15/2020Jatin ShahEVPSell589$19.46$11,461.9443,172View SEC Filing Icon  
7/15/2020Michael KauffmanCEOSell7,500$19.43$145,725.00555,122View SEC Filing Icon  
7/10/2020Sharon ShachamInsiderSell15,000$19.27$289,050.00
7/9/2020Michael KauffmanCEOSell7,500$19.53$146,475.00562,622View SEC Filing Icon  
6/15/2020Michael KauffmanCEOSell7,500$16.37$122,775.00555,122View SEC Filing Icon  
6/10/2020Sharon ShachamInsiderSell15,000$16.60$249,000.00
6/9/2020Michael KauffmanCEOSell7,500$18.50$138,750.00562,622View SEC Filing Icon  
4/8/2020Michael KauffmanCEOSell10,000$18.61$186,100.00565,122View SEC Filing Icon  
See Full Table

SEC Filings (Institutional Ownership Changes) for Karyopharm Therapeutics (NASDAQ:KPTI)

96.13% of Karyopharm Therapeutics stock is owned by institutions. Institutional ownership can be a sign of analyst confidence in the fundamentals of the stock.

Institutional Buying and Selling by Quarter

This chart shows the instiutional buying and selling at KPTI by year and by quarter.

Skip Institutional Buying and Selling Chart and Table DataRead Chart Data in Institutional Trading History Table

Karyopharm Therapeutics Institutional Trading History

Reporting DateHedge FundShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
3/23/2023MetLife Investment Management LLC29,394$100K0.0%-29.0%0.026%Search for SEC Filing on Google Icon
2/28/2023Voya Investment Management LLC28,866$98K0.0%-83.2%0.025%Search for SEC Filing on Google Icon
2/16/2023Alliancebernstein L.P.158,030$0.54M0.0%+14.4%0.195%Search for SEC Filing on Google Icon
2/16/2023Point72 Middle East FZE47,257$0.16M0.0%N/A0.058%Search for SEC Filing on Google Icon
2/16/2023State of Wyoming17,082$58K0.0%+188.8%0.021%Search for SEC Filing on Google Icon
2/15/2023MetLife Investment Management LLC29,394$100K0.0%-29.0%0.036%Search for SEC Filing on Google Icon
2/15/2023Tejara Capital Ltd501,562$1.71M1.0%N/A0.618%Search for SEC Filing on Google Icon
2/15/2023State of Wisconsin Investment Board10,048$34K0.0%-85.6%0.012%Search for SEC Filing on Google Icon
2/15/2023Squarepoint Ops LLC52,283$0.18M0.0%N/A0.064%Search for SEC Filing on Google Icon
2/15/2023Legal & General Group Plc45,819$0.16M0.0%+21.2%0.056%Search for SEC Filing on Google Icon
2/15/2023Millennium Management LLC351,543$1.20M0.0%+33.8%0.433%Search for SEC Filing on Google Icon
2/15/2023Morgan Stanley1,289,437$4.38M0.0%+19.4%1.589%Search for SEC Filing on Google Icon
2/15/2023E Fund Management Co. Ltd.36,504$0.12M0.0%-20.5%0.045%Search for SEC Filing on Google Icon
2/15/2023Algert Global LLC82,668$0.28M0.0%-13.8%0.102%Search for SEC Filing on Google Icon
2/15/2023AQR Capital Management LLC61,647$0.21M0.0%-45.3%0.076%Search for SEC Filing on Google Icon
2/15/2023Armistice Capital LLC3,853,565$13.10M0.2%N/A4.748%Search for SEC Filing on Google Icon
2/15/2023Avidity Partners Management LP9,633,911$32.76M0.7%N/A11.871%Search for SEC Filing on Google Icon
2/14/2023Point72 Asset Management L.P.1,991,613$6.77M0.0%+56,803.2%2.454%Search for SEC Filing on Google Icon
2/14/2023Alyeska Investment Group L.P.481,696$1.64M0.0%N/A0.594%Search for SEC Filing on Google Icon
2/14/2023Price T Rowe Associates Inc. MD57,955$0.20M0.0%+10.3%0.071%Search for SEC Filing on Google Icon
2/14/2023Putnam Investments LLC242,620$0.83M0.0%N/A0.299%Search for SEC Filing on Google Icon
2/14/2023Marshall Wace LLP2,210,223$7.52M0.0%+1,288.9%2.723%Search for SEC Filing on Google Icon
2/14/2023Alpine Global Management LLC17,081$58K0.0%N/A0.021%Search for SEC Filing on Google Icon
2/14/2023Two Sigma Investments LP265,308$0.90M0.0%+16.2%0.327%Search for SEC Filing on Google Icon
2/14/2023Engineers Gate Manager LP49,552$0.17M0.0%+60.9%0.061%Search for SEC Filing on Google Icon
2/13/2023Charles Schwab Investment Management Inc.206,831$0.70M0.0%+3.2%0.255%Search for SEC Filing on Google Icon
2/13/2023Barclays PLC1,046,712$3.56M0.0%+129.8%1.290%Search for SEC Filing on Google Icon
2/13/2023Renaissance Technologies LLC189,300$0.64M0.0%-38.6%0.233%Search for SEC Filing on Google Icon
2/13/2023ExodusPoint Capital Management LP1,106,132$3.76M0.1%+56.4%1.363%Search for SEC Filing on Google Icon
2/13/2023Martingale Asset Management L P45,315$0.15M0.0%N/A0.056%Search for SEC Filing on Google Icon
2/13/2023Geode Capital Management LLC1,377,128$4.68M0.0%+3.5%1.697%Search for SEC Filing on Google Icon
2/13/2023GSA Capital Partners LLP82,162$0.28M0.0%N/A0.101%Search for SEC Filing on Google Icon
2/13/2023JPMorgan Chase & Co.1,482,164$5.04M0.0%+727.0%1.826%Search for SEC Filing on Google Icon
2/13/2023Teacher Retirement System of Texas28,597$97K0.0%+22.4%0.035%Search for SEC Filing on Google Icon
2/10/2023Opaleye Management Inc.1,206,841$4.28M1.5%N/A1.487%Search for SEC Filing on Google Icon
2/10/2023Bank of America Corp DE1,511,166$5.14M0.0%+106.5%1.862%Search for SEC Filing on Google Icon
2/10/2023New York Life Investment Management LLC76,968$0.26M0.0%+12.7%0.095%Search for SEC Filing on Google Icon
2/10/2023Connor Clark & Lunn Investment Management Ltd.432,278$1.47M0.0%+178.1%0.533%Search for SEC Filing on Google Icon
2/10/2023Advisor Group Holdings Inc.8,906$30K0.0%+134.3%0.011%Search for SEC Filing on Google Icon
2/10/2023Moors & Cabot Inc.12,200$41K0.0%-42.3%0.015%Search for SEC Filing on Google Icon
2/9/2023Principal Financial Group Inc.56,805$0.19M0.0%+186.5%0.070%Search for SEC Filing on Google Icon
2/9/2023Monashee Investment Management LLC481,696$1.64M0.7%N/A0.594%Search for SEC Filing on Google Icon
2/9/2023Citigroup Inc.508,593$1.73M0.0%-16.3%0.627%Search for SEC Filing on Google Icon
2/8/2023UBS Group AG523,259$1.78M0.0%+364.9%0.645%Search for SEC Filing on Google Icon
2/8/2023Swiss National Bank259,150$0.88M0.0%+52.9%0.319%Search for SEC Filing on Google Icon
2/8/2023Russell Investments Group Ltd.146,160$0.50M0.0%+12.9%0.180%Search for SEC Filing on Google Icon
2/7/2023State Board of Administration of Florida Retirement System27,015$92K0.0%-49.1%0.033%Search for SEC Filing on Google Icon
2/7/2023Fox Run Management L.L.C.28,823$98K0.0%N/A0.036%Search for SEC Filing on Google Icon
2/6/2023Los Angeles Capital Management LLC101,917$0.35M0.0%+29.6%0.126%Search for SEC Filing on Google Icon
2/3/2023Birchview Capital LP291,332$0.99M0.7%+8.2%0.359%Search for SEC Filing on Google Icon
2/1/2023Redwood Wealth Management Group LLC33,230$0.11M0.1%N/A0.041%Search for SEC Filing on Google Icon
2/1/2023Janney Montgomery Scott LLC10,000$34K0.0%N/A0.012%Search for SEC Filing on Google Icon
1/30/2023New York State Common Retirement Fund49,074$0.17M0.0%-27.2%0.060%Search for SEC Filing on Google Icon
1/26/2023Dupont Capital Management Corp22,957$78K0.0%N/A0.028%Search for SEC Filing on Google Icon
1/23/2023Allspring Global Investments Holdings LLC26,599$90K0.0%-27.2%0.033%Search for SEC Filing on Google Icon
1/12/2023Hennion & Walsh Asset Management Inc.144,353$0.49M0.0%-47.8%0.178%Search for SEC Filing on Google Icon
12/8/2022Bank of New York Mellon Corp298,991$1.63M0.0%+4.4%0.368%Search for SEC Filing on Google Icon
11/16/2022Balyasny Asset Management LLC595,558$3.25M0.0%+592.0%0.734%Search for SEC Filing on Google Icon
11/16/2022BNP Paribas Arbitrage SNC762,520$4.16M0.0%+30.5%0.940%Search for SEC Filing on Google Icon
11/15/2022Alliancebernstein L.P.138,130$0.75M0.0%+17.0%0.170%Search for SEC Filing on Google Icon
11/15/2022State Street Corp9,010,339$49.20M0.0%-13.0%11.103%Search for SEC Filing on Google Icon
11/15/2022Jacobs Levy Equity Management Inc.1,582,524$8.64M0.1%+3.6%1.950%Search for SEC Filing on Google Icon
11/15/2022Algert Global LLC95,958$0.52M0.0%-32.2%0.118%Search for SEC Filing on Google Icon
11/15/2022Mercer Global Advisors Inc. ADV11,425$62K0.0%N/A0.014%Search for SEC Filing on Google Icon
11/15/2022Two Sigma Advisers LP831,300$4.54M0.0%-15.7%1.024%Search for SEC Filing on Google Icon
11/15/2022Two Sigma Investments LP228,335$1.25M0.0%-77.7%0.281%Search for SEC Filing on Google Icon
11/15/2022Trexquant Investment LP119,526$0.65M0.0%+24.3%0.147%Search for SEC Filing on Google Icon
11/15/2022Vanguard Group Inc.4,813,399$26.28M0.0%+14.0%5.931%Search for SEC Filing on Google Icon
11/15/2022Price T Rowe Associates Inc. MD52,532$0.29M0.0%+39.5%0.065%Search for SEC Filing on Google Icon
11/15/2022Marshall Wace LLP159,137$0.87M0.0%+591.9%0.196%Search for SEC Filing on Google Icon
11/15/2022Engineers Gate Manager LP30,790$0.17M0.0%-37.1%0.038%Search for SEC Filing on Google Icon
11/15/2022Frontier Capital Management Co. LLC629,154$3.44M0.0%-0.5%0.775%Search for SEC Filing on Google Icon
11/15/2022Bank of New York Mellon Corp298,991$1.63M0.0%+4.4%0.368%Search for SEC Filing on Google Icon
11/15/2022BlackRock Inc.7,912,954$43.20M0.0%-2.6%9.751%Search for SEC Filing on Google Icon
11/15/2022Caxton Associates LP71,903$0.39M0.1%+41.0%0.089%Search for SEC Filing on Google Icon
11/15/2022Commonwealth Equity Services LLC10,165$55K0.0%-21.7%0.013%Search for SEC Filing on Google Icon
11/14/2022Royal Bank of Canada11,175$61K0.0%-16.1%0.014%Search for SEC Filing on Google Icon
11/14/2022Tudor Investment Corp Et Al60,064$0.33M0.0%+10.2%0.074%Search for SEC Filing on Google Icon
11/14/2022Cubist Systematic Strategies LLC88,364$0.48M0.0%-53.6%0.109%Search for SEC Filing on Google Icon
11/14/2022Renaissance Technologies LLC308,300$1.68M0.0%-32.2%0.380%Search for SEC Filing on Google Icon
11/14/2022Nuveen Asset Management LLC1,971,048$10.76M0.0%+4.0%2.429%Search for SEC Filing on Google Icon
11/14/2022Altium Capital Management LP750,000$4.10M1.5%+7.1%0.924%Search for SEC Filing on Google Icon
11/14/2022Rubric Capital Management LP3,990,126$21.79M1.1%-9.3%4.917%Search for SEC Filing on Google Icon
11/14/2022UBS Oconnor LLC271,219$1.48M0.0%+19.2%0.334%Search for SEC Filing on Google Icon
11/14/2022MetLife Investment Management LLC41,409$0.23M0.0%+78.4%0.051%Search for SEC Filing on Google Icon
11/14/2022Metropolitan Life Insurance Co NY4,622$25K0.0%+73.9%0.006%Search for SEC Filing on Google Icon
11/14/2022E Fund Management Co. Ltd.45,924$0.25M0.0%-12.8%0.057%Search for SEC Filing on Google Icon
11/14/2022Hennion & Walsh Asset Management Inc.276,422$1.51M0.1%-3.6%0.341%Search for SEC Filing on Google Icon
11/10/2022Connor Clark & Lunn Investment Management Ltd.155,433$0.85M0.0%+238.1%0.192%Search for SEC Filing on Google Icon
11/10/2022ExodusPoint Capital Management LP707,280$3.86M0.1%+9.5%0.872%Search for SEC Filing on Google Icon
11/10/2022Tower Research Capital LLC TRC34,397$0.19M0.0%+18.2%0.042%Search for SEC Filing on Google Icon
11/10/2022UBS Group AG112,546$0.61M0.0%-64.6%0.139%Search for SEC Filing on Google Icon
11/8/2022New York State Common Retirement Fund67,406$0.37M0.0%+37.9%0.083%Search for SEC Filing on Google Icon
11/7/2022Nisa Investment Advisors LLC5,700$26K0.0%+612.5%0.007%Search for SEC Filing on Google Icon
11/4/2022Prudential Financial Inc.31,700$0.17M0.0%-38.4%0.040%Search for SEC Filing on Google Icon
11/4/2022Russell Investments Group Ltd.129,415$0.71M0.0%+18.6%0.162%Search for SEC Filing on Google Icon
11/3/2022Teacher Retirement System of Texas23,373$0.13M0.0%+115.3%0.029%Search for SEC Filing on Google Icon
11/3/2022Barclays PLC455,464$2.49M0.0%+456.0%0.571%Search for SEC Filing on Google Icon
11/2/2022Los Angeles Capital Management LLC78,657$0.43M0.0%+321.1%0.099%Search for SEC Filing on Google Icon
11/1/2022Rice Hall James & Associates LLC909,083$4.96M0.3%-30.9%1.139%Search for SEC Filing on Google Icon
Data available starting January 2016

See Full Table
Karyopharm Therapeutics logo
Karyopharm Therapeutics, Inc. is a commercial-stage pharmaceutical company, which engages in the discovery, development, and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. Its Selective Inhibitor of Nuclear Export (SINE) compounds function by binding with and inhibiting the nuclear export protein XPO1 (or CRM1). Karyopharm's compound, XPOVIO (selinexor), is approved in the U.S. in multiple hematologic malignancy indications, including in combination with Velcade (bortezomib) and dexamethasone for the treatment of adult patients with multiple myeloma after at least one prior therapy, in combination with dexamethasone for the treatment of adult patients with pretreated multiple myeloma and as a monotherapy for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma. In addition to single-agent and combination activity against a variety of human cancers, SINE compounds have also shown biological activity in models of neurodegeneration, inflammation, autoimmune disease, certain viruses, and wound-healing. Karyopharm has several investigational programs in clinical or preclinical development.
Read More on Karyopharm Therapeutics

Today's Range

Now: $3.52
Low: $3.50
High: $4.06

50 Day Range

MA: $3.31
Low: $2.95
High: $3.92

52 Week Range

Now: $3.52
Low: $2.45
High: $8.63

Volume

2,444,874 shs

Average Volume

2,697,873 shs

Market Capitalization

$398.96 million

P/E Ratio

N/A

Dividend Yield

N/A

Beta

0.04

Who are the company insiders with the largest holdings of Karyopharm Therapeutics?

Karyopharm Therapeutics' top insider shareholders include:
  1. Richard A Paulson (CEO)
  2. Michael Mason (CFO)
  3. Sohanya Roshan Cheng (EVP)
  4. Stephen Mitchener (SVP)
  5. Sohanya Roshan Cheng (Insider)
  6. Stuart Poulton (EVP)
  7. Deepika Pakianathan (Director)
  8. Garen G Bohlin (Director)
  9. Jatin Shah (EVP)
  10. Michael Kauffman (Director)
  11. Sharon Shacham (Insider)
Learn More about top insider investors at Karyopharm Therapeutics.

Who are the major institutional investors of Karyopharm Therapeutics?

Karyopharm Therapeutics' top institutional shareholders include:
  1. Avidity Partners Management LP — 11.87%
  2. Armistice Capital LLC — 4.75%
  3. Marshall Wace LLP — 2.72%
  4. Point72 Asset Management L.P. — 2.45%
  5. Bank of America Corp DE — 1.86%
  6. JPMorgan Chase & Co. — 1.83%
Learn More about top institutional investors of Karyopharm Therapeutics stock.

Which major investors are selling Karyopharm Therapeutics stock?

Within the previous quarter, KPTI stock was sold by these institutional investors:
  1. Voya Investment Management LLC
  2. Hennion & Walsh Asset Management Inc.
  3. Renaissance Technologies LLC
  4. Citigroup Inc.
  5. State of Wisconsin Investment Board
  6. AQR Capital Management LLC
  7. Susquehanna International Group LLP
  8. State Board of Administration of Florida Retirement System
Within the last year, company insiders that have sold Karyopharm Therapeutics company stock include:
  1. Richard A Paulson (CEO)
  2. Michael Mason (CFO)
  3. Sohanya Roshan Cheng (EVP)
  4. Stephen Mitchener (SVP)
  5. Sohanya Roshan Cheng (Insider)
  6. Stuart Poulton (EVP)
  7. Deepika Pakianathan (Director)
Learn More investors selling Karyopharm Therapeutics stock.

Which major investors are buying Karyopharm Therapeutics stock?

In the last quarter, KPTI stock was purchased by institutional investors including:
  1. Avidity Partners Management LP
  2. Armistice Capital LLC
  3. Marshall Wace LLP
  4. Point72 Asset Management L.P.
  5. JPMorgan Chase & Co.
  6. Opaleye Management Inc.
  7. Bank of America Corp DE
  8. Barclays PLC
In the previous year, these company insiders have bought Karyopharm Therapeutics stock:
  1. Richard A Paulson (CEO)
  2. Michael Mason (CFO)
Learn More investors buying Karyopharm Therapeutics stock.