LYEL Insider Trading

Insider Ownership Percentage: 22.30%
Insider Buying (Last 12 Months): $449,508.40
Insider Selling (Last 12 Months): $30,063.50

Lyell Immunopharma Insider Trading History Chart

This chart shows the insider buying and selling history at Lyell Immunopharma by year and by quarter.

Skip ChartChart Data in Insider Trading History Table

Lyell Immunopharma Share Price & Price History

Current Price: $25.46
Price Change: Price Increase of +3.15 (14.12%)
As of 12/4/2025 05:00 PM ET

This chart shows the closing price history over time for LYEL up to the past year.

Skip Chart and Table DataPrice Data in Insider Trading History Table
Days: 30 | 90 | 365

Lyell Immunopharma Insider Trading History

Transaction DateInsider NameTitleBuy/SellNumber of SharesAverage Share PriceTotal TransactionShares Held After TransactionDetails
11/10/2025Gary K LeeInsiderSell138$16.16$2,230.0815,366View SEC Filing Icon  
11/10/2025Lynn SeelyCEOSell412$16.11$6,637.3267,159View SEC Filing Icon  
11/10/2025Stephen J HillCOOSell95$16.12$1,531.4015,750View SEC Filing Icon  
11/10/2025Veronica Sanchez BulisVPSell239$16.10$3,847.909,213View SEC Filing Icon  
8/12/2025Charles W NewtonCFOSell136$10.34$1,406.248,759View SEC Filing Icon  
8/12/2025Gary K LeeInsiderSell136$10.34$1,406.248,957View SEC Filing Icon  
8/12/2025Lynn SeelyCEOSell406$10.34$4,198.0434,828View SEC Filing Icon  
8/12/2025Stephen J HillCOOSell94$10.34$971.968,849View SEC Filing Icon  
8/11/2025Charles W NewtonCFOSell131$10.53$1,379.438,895View SEC Filing Icon  
8/11/2025Gary K LeeInsiderSell131$10.53$1,379.439,093View SEC Filing Icon  
8/11/2025Lynn SeelyCEOSell391$10.53$4,117.2335,234View SEC Filing Icon  
8/11/2025Stephen J HillCOOSell91$10.53$958.238,943View SEC Filing Icon  
3/31/2025Otis W BrawleyDirectorBuy1,782$11.20$19,958.401,782View SEC Filing Icon  
3/21/2025Sumant RamachandraDirectorBuy10,000$11.60$116,000.0010,000View SEC Filing Icon  
3/17/2025Charles W NewtonCFOBuy10,000$11.20$112,000.0010,000View SEC Filing Icon  
3/14/2025Lynn SeelyCEOBuy8,750$12.20$106,750.0035,625View SEC Filing Icon  
3/14/2025Richard KlausnerDirectorBuy7,900$12.00$94,800.0042,168View SEC Filing Icon  
See Full Table

SEC Filings (Institutional Ownership Changes) for Lyell Immunopharma (NASDAQ:LYEL)

66.05% of Lyell Immunopharma stock is owned by institutions. Institutional ownership can be a sign of analyst confidence in the fundamentals of the stock.

Institutional Buying and Selling by Quarter

This chart shows the instiutional buying and selling at LYEL by year and by quarter.

Skip Institutional Buying and Selling Chart and Table DataRead Chart Data in Institutional Trading History Table

Lyell Immunopharma Institutional Trading History

Reporting DateHedge FundShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
11/17/2025Susquehanna International Group LLP16,159$0.26M0.0%-27.9%0.076%Search for SEC Filing on Google Icon
11/17/2025Millennium Management LLC125,361$2.04M0.0%+140.0%0.591%Search for SEC Filing on Google Icon
11/17/2025Foresite Capital Management V LLC477,078$7.75M7.1%+17.3%2.248%Search for SEC Filing on Google Icon
11/17/2025Bank of America Corp DE4,679$76K0.0%-80.3%0.022%Search for SEC Filing on Google Icon
11/17/2025Almitas Capital LLC577,807$9.38M2.1%-0.4%2.723%Search for SEC Filing on Google Icon
11/14/2025ARCH Venture Management LLC2,759,072$44.81M9.1%+51.5%14.362%Search for SEC Filing on Google Icon
11/14/2025Two Sigma Investments LP20,827$0.34M0.0%+107.0%0.108%Search for SEC Filing on Google Icon
11/13/2025Takeda Pharmaceutical Co. Ltd.54,887$0.89M5.4%+33.3%0.286%Search for SEC Filing on Google Icon
11/7/2025Vanguard Group Inc.779,004$12.65M0.0%+76.0%4.055%Search for SEC Filing on Google Icon
10/14/2025Clarius Group LLC19,958$0.32M0.0%+4.3%0.104%Search for SEC Filing on Google Icon
8/28/2025China Universal Asset Management Co. Ltd.2,966$26K0.0%-94.9%0.015%Search for SEC Filing on Google Icon
8/15/2025Orland Properties Ltd754,698$6.67M2.8%-95.0%3.929%Search for SEC Filing on Google Icon
8/15/2025MWG Management Ltd.1,008,116$8.91M17.2%-95.0%5.248%Search for SEC Filing on Google Icon
8/15/2025HSG Holding Ltd152,299$1.35M0.1%-95.0%0.793%Search for SEC Filing on Google Icon
8/15/2025Boothbay Fund Management LLC12,234$0.11M0.0%-95.0%0.064%Search for SEC Filing on Google Icon
8/15/2025Bridgeway Capital Management LLC18,000$0.16M0.0%N/A0.094%Search for SEC Filing on Google Icon
8/15/2025Bank of America Corp DE23,758$0.21M0.0%-74.7%0.124%Search for SEC Filing on Google Icon
8/15/2025ARCH Venture Management LLC1,820,634$16.11M5.4%N/A9.478%Search for SEC Filing on Google Icon
8/14/2025Orbimed Advisors LLC51,727$0.46M0.0%N/A0.335%Search for SEC Filing on Google Icon
8/14/2025Raymond James Financial Inc.7,900$70K0.0%-95.0%0.051%Search for SEC Filing on Google Icon
8/14/2025Canada Pension Plan Investment Board29,411$0.26M0.0%-95.0%0.190%Search for SEC Filing on Google Icon
8/14/2025The Manufacturers Life Insurance Company 24,419$0.22M0.0%-95.2%0.158%Search for SEC Filing on Google Icon
8/14/2025RBF Capital LLC100,000$0.88M0.0%N/A0.647%Search for SEC Filing on Google Icon
8/13/2025Marshall Wace LLP10,580$94K0.0%N/A0.068%Search for SEC Filing on Google Icon
8/13/2025Walleye Capital LLC29,230$0.26M0.0%N/A0.189%Search for SEC Filing on Google Icon
8/13/2025Decheng Capital LLC595,466$5.26M1.2%-95.0%3.852%Search for SEC Filing on Google Icon
8/13/2025Invesco Ltd.12,809$0.11M0.0%-96.6%0.083%Search for SEC Filing on Google Icon
8/12/2025Foresite Capital Management V LLC406,652$3.60M4.5%-95.0%2.630%Search for SEC Filing on Google Icon
8/12/2025Foresite Capital Management IV LLC800,399$7.08M5.7%-95.0%5.177%Search for SEC Filing on Google Icon
8/12/2025JPMorgan Chase & Co.3,369$30K0.0%-98.3%0.022%Search for SEC Filing on Google Icon
8/8/2025Geode Capital Management LLC103,270$0.91M0.0%-97.7%0.668%Search for SEC Filing on Google Icon
8/8/2025Takeda Pharmaceutical Co. Ltd.41,165$0.36M1.9%-95.0%0.266%Search for SEC Filing on Google Icon
8/1/2025Alphabet Inc.293,256$2.59M0.1%-95.0%1.980%Search for SEC Filing on Google Icon
7/28/2025TD Asset Management Inc50,232$0.44M0.0%-95.0%0.339%Search for SEC Filing on Google Icon
7/22/2025Johnson & Johnson41,165$0.37M0.1%-95.0%0.278%Search for SEC Filing on Google Icon
7/22/2025Clarius Group LLC19,138$0.17M0.0%-95.2%0.129%Search for SEC Filing on Google Icon
6/27/2025Goldman Sachs Group Inc.358,592$0.19M0.0%-42.8%2.421%Search for SEC Filing on Google Icon
6/18/2025Voya Investment Management LLC50,329$27K0.0%-4.9%0.340%Search for SEC Filing on Google Icon
5/29/2025Rhumbline Advisers235,694$0.13M0.0%-16.2%0.080%Search for SEC Filing on Google Icon
5/21/2025Acadian Asset Management LLC660,899$0.35M0.0%+204.2%0.224%Search for SEC Filing on Google Icon
5/19/2025Jane Street Group LLC64,241$35K0.0%-73.2%0.022%Search for SEC Filing on Google Icon
5/16/2025Goldman Sachs Group Inc.358,592$0.19M0.0%-42.8%0.121%Search for SEC Filing on Google Icon
5/16/2025Jacobs Levy Equity Management Inc.558,979$0.30M0.0%-59.6%0.189%Search for SEC Filing on Google Icon
5/16/2025AQR Capital Management LLC174,279$94K0.0%+773.5%0.059%Search for SEC Filing on Google Icon
5/16/2025Almitas Capital LLC2,482,606$1.34M0.4%+136.3%0.841%Search for SEC Filing on Google Icon
5/12/2025Nuveen LLC641,173$0.35M0.0%N/A0.217%Search for SEC Filing on Google Icon
5/12/2025Invesco Ltd.378,880$0.20M0.0%-7.0%0.128%Search for SEC Filing on Google Icon
5/9/2025Charles Schwab Investment Management Inc.1,604,676$0.86M0.0%-2.5%0.543%Search for SEC Filing on Google Icon
4/17/2025Exchange Traded Concepts LLC246,349$0.13M0.0%+82.4%0.083%Search for SEC Filing on Google Icon
4/8/2025Rhumbline Advisers235,694$0.13M0.0%-16.2%0.080%Search for SEC Filing on Google Icon
2/19/2025Public Employees Retirement System of Ohio99,307$64K0.0%N/A0.034%Search for SEC Filing on Google Icon
2/17/2025venBio Partners LLC7,102,190$4.55M2.7%N/A2.431%Search for SEC Filing on Google Icon
2/17/2025Two Sigma Investments LP204,501$0.13M0.0%-15.4%0.070%Search for SEC Filing on Google Icon
2/17/2025Two Sigma Advisers LP306,400$0.20M0.0%+143.8%0.105%Search for SEC Filing on Google Icon
2/17/2025Nuveen Asset Management LLC641,173$0.41M0.0%-25.1%0.219%Search for SEC Filing on Google Icon
2/17/2025Orbimed Advisors LLC3,103,623$1.99M0.0%-49.0%1.062%Search for SEC Filing on Google Icon
2/17/2025Millennium Management LLC957,507$0.61M0.0%+34.8%0.328%Search for SEC Filing on Google Icon
2/17/2025MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.308,551$0.20M0.0%+13.4%0.106%Search for SEC Filing on Google Icon
2/17/2025Jacobs Levy Equity Management Inc.1,385,301$0.89M0.0%N/A0.474%Search for SEC Filing on Google Icon
2/17/2025Graham Capital Management L.P.52,136$33K0.0%N/A0.018%Search for SEC Filing on Google Icon
2/17/2025Foresite Capital Management V LLC8,133,047$5.21M4.3%N/A2.784%Search for SEC Filing on Google Icon
2/17/2025D. E. Shaw & Co. Inc.966,265$0.62M0.0%+104.4%0.331%Search for SEC Filing on Google Icon
2/17/2025BNP Paribas Financial Markets253,669$0.16M0.0%N/A0.087%Search for SEC Filing on Google Icon
2/17/2025Almitas Capital LLC1,050,520$0.67M0.1%N/A0.360%Search for SEC Filing on Google Icon
2/14/2025Jane Street Group LLC239,439$0.15M0.0%-16.8%0.082%Search for SEC Filing on Google Icon
2/14/2025Northern Trust Corp1,310,224$0.84M0.0%-3.4%0.448%Search for SEC Filing on Google Icon
2/14/2025Decheng Capital LLC11,909,341$7.62M1.6%N/A4.076%Search for SEC Filing on Google Icon
2/14/2025Boothbay Fund Management LLC406,234$0.26M0.0%+190.4%0.139%Search for SEC Filing on Google Icon
2/14/2025Price T Rowe Associates Inc. MD6,910,749$4.42M0.0%-6.0%2.365%Search for SEC Filing on Google Icon
2/14/2025Johnson & Johnson823,317$0.53M0.1%N/A0.282%Search for SEC Filing on Google Icon
2/13/2025Barclays PLC258,380$0.17M0.0%+7.4%0.088%Search for SEC Filing on Google Icon
2/13/2025Renaissance Technologies LLC1,612,146$1.03M0.0%+716.7%0.552%Search for SEC Filing on Google Icon
2/13/2025Wells Fargo & Company MN94,320$60K0.0%+27.8%0.032%Search for SEC Filing on Google Icon
2/12/2025RPO LLC66,378$42K0.0%N/A0.023%Search for SEC Filing on Google Icon
2/12/2025Geode Capital Management LLC4,137,264$2.65M0.0%+2.9%1.416%Search for SEC Filing on Google Icon
2/12/2025Takeda Pharmaceutical Co. Ltd.823,317$0.53M2.0%N/A0.282%Search for SEC Filing on Google Icon
2/12/2025JPMorgan Chase & Co.433,265$0.28M0.0%+347.8%0.148%Search for SEC Filing on Google Icon
2/11/2025Prudential Financial Inc.48,057$31K0.0%-66.8%0.016%Search for SEC Filing on Google Icon
2/6/2025Charles Schwab Investment Management Inc.1,645,787$1.05M0.0%+43.4%0.563%Search for SEC Filing on Google Icon
1/17/2025SG Americas Securities LLC116,748$75K0.0%+102.8%0.040%Search for SEC Filing on Google Icon
11/19/2024Barclays PLC240,615$0.33M0.0%+312.7%0.082%Search for SEC Filing on Google Icon
11/15/2024Barclays PLC240,615$0.33M0.0%+312.7%0.086%Search for SEC Filing on Google Icon
11/15/2024Jane Street Group LLC287,717$0.40M0.0%+63.7%0.103%Search for SEC Filing on Google Icon
11/15/2024State Street Corp3,889,553$5.37M0.0%+1.9%1.393%Search for SEC Filing on Google Icon
11/15/2024Centiva Capital LP22,160$31K0.0%N/A0.008%Search for SEC Filing on Google Icon
11/15/2024Point72 Asia Singapore Pte. Ltd.37,704$52K0.0%N/A0.014%Search for SEC Filing on Google Icon
11/15/2024Erste Asset Management GmbH54,000$82K0.0%N/A0.019%Search for SEC Filing on Google Icon
11/14/2024MetLife Investment Management LLC36,287$50K0.0%-57.5%0.013%Search for SEC Filing on Google Icon
11/13/2024FMR LLC1,024,583$1.41M0.0%-62.5%0.367%Search for SEC Filing on Google Icon
11/12/2024Charles Schwab Investment Management Inc.1,147,370$1.58M0.0%-11.6%0.448%Search for SEC Filing on Google Icon
11/9/2024Intech Investment Management LLC37,495$52K0.0%N/A0.015%Search for SEC Filing on Google Icon
11/8/2024WuXi AppTec Co. Ltd.7,390,710$10.20M53.6%-3.8%2.887%Search for SEC Filing on Google Icon
11/6/2024Cornercap Investment Counsel Inc.47,763$66K0.0%-50.4%0.019%Search for SEC Filing on Google Icon
11/5/2024Baillie Gifford & Co.141,949$0.20M0.0%-72.7%0.055%Search for SEC Filing on Google Icon
11/5/2024GSA Capital Partners LLP354,815$0.49M0.0%+1,285.5%0.139%Search for SEC Filing on Google Icon
10/25/2024China Universal Asset Management Co. Ltd.49,238$68K0.0%+64.4%0.019%Search for SEC Filing on Google Icon
10/10/2024Exchange Traded Concepts LLC135,050$0.19M0.0%+37.3%0.053%Search for SEC Filing on Google Icon
10/3/2024SG Americas Securities LLC57,566$79K0.0%+78.1%0.023%Search for SEC Filing on Google Icon
8/15/2024Susquehanna Fundamental Investments LLC128,203$0.19M0.0%+49.5%0.050%Search for SEC Filing on Google Icon
8/15/2024The Manufacturers Life Insurance Company553,163$0.80M0.0%+14.4%0.217%Search for SEC Filing on Google Icon
Data available starting January 2016

See Full Table
Lyell Immunopharma logo
Lyell Immunopharma, Inc., a clinical-stage cell therapy company, develops T cell reprogramming technologies for patients with solid tumors. The company develops therapies using an ex vivo genetic reprogramming technologies, such as c Jun overexpression and NR4A3 gene knockout, to endow resistance to T cell exhaustion; and an ex vivo epigenetic reprogramming technologies, including Epi R to generate population of T cells with durable stemness, and Stim R, a proprietary synthetic cell mimetic. It is also developing LYL797, a genetically and epigenetically reprogrammed ROR1 chimeric antigen receptor (CAR) T cell product candidate that is in Phase 1 clinical trial for the treatment of various solid tumors; and LYL845, a novel epigenetically reprogrammed tumor-infiltrating lymphocytes product candidate, which is in Phase 1 clinical trial targeting multiple solid tumor indications. In addition, the company's preclinical product candidates include LYL119, a ROR1 CAR T-cell product for the treatment of enhanced cytotoxicity; and second generation TIL product. Lyell Immunopharma, Inc. was incorporated in 2018 and is headquartered in South San Francisco, California.
Read More on Lyell Immunopharma

Today's Range

Now: $25.46
Low: $21.39
High: $25.59

50 Day Range

MA: $18.18
Low: $12.83
High: $25.46

52 Week Range

Now: $25.46
Low: $7.65
High: $25.59

Volume

93,527 shs

Average Volume

39,594 shs

Market Capitalization

$540.26 million

P/E Ratio

N/A

Dividend Yield

N/A

Beta

N/A

Who are the company insiders with the largest holdings of Lyell Immunopharma?

Lyell Immunopharma's top insider investors include:
  1. Lynn Seely (CEO)
  2. Richard Klausner (Director)
  3. Stephen J Hill (COO)
  4. Gary K Lee (Insider)
  5. Charles W Newton (CFO)
  6. Sumant Ramachandra (Director)
  7. Veronica Sanchez Bulis (VP)
  8. Otis W Brawley (Director)
Learn More about top insider investors at Lyell Immunopharma.

Who are the major institutional investors of Lyell Immunopharma?

Lyell Immunopharma's top institutional investors include:
  1. ARCH Venture Management LLC — 14.36%
  2. Vanguard Group Inc. — 4.06%
  3. Almitas Capital LLC — 2.72%
  4. Foresite Capital Management V LLC — 2.25%
  5. Millennium Management LLC — 0.59%
  6. Takeda Pharmaceutical Co. Ltd. — 0.29%
Learn More about top institutional investors of Lyell Immunopharma stock.

Which major investors are selling Lyell Immunopharma stock?

In the previous quarter, LYEL stock was sold by these institutional investors:
  1. Bank of America Corp DE
  2. Susquehanna International Group LLP
  3. Group One Trading LLC
  4. Almitas Capital LLC
Within the last year, company insiders that have sold Lyell Immunopharma company stock include:
  1. Lynn Seely (CEO)
  2. Richard Klausner (Director)
  3. Stephen J Hill (COO)
  4. Gary K Lee (Insider)
  5. Charles W Newton (CFO)
Learn More investors selling Lyell Immunopharma stock.

Which major investors are buying Lyell Immunopharma stock?

During the previous quarter, LYEL stock was acquired by institutional investors including:
  1. ARCH Venture Management LLC
  2. Vanguard Group Inc.
  3. Millennium Management LLC
  4. Foresite Capital Management V LLC
  5. Takeda Pharmaceutical Co. Ltd.
  6. Two Sigma Investments LP
  7. Clarius Group LLC
  8. Citadel Advisors LLC
Within the last year, these company insiders have bought Lyell Immunopharma stock:
  1. Lynn Seely (CEO)
  2. Richard Klausner (Director)
  3. Stephen J Hill (COO)
  4. Gary K Lee (Insider)
  5. Charles W Newton (CFO)
Learn More investors buying Lyell Immunopharma stock.