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PRAX Insider Trading

Insider Ownership Percentage: 2.70%
Insider Buying (Last 12 Months): $0.00
Insider Selling (Last 12 Months): $7,464,639.70

Praxis Precision Medicines Insider Trading History Chart

This chart shows the insider buying and selling history at Praxis Precision Medicines by year and by quarter.

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Praxis Precision Medicines Share Price & Price History

Current Price: $189.97
Price Change: ▲ Price Increase of +3.82 (2.05%)
As of 12/4/2025 05:00 PM ET

This chart shows the closing price history over time for PRAX up to the past year.

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Days: 30 | 90 | 365

Praxis Precision Medicines Insider Trading History

Transaction DateInsider NameTitleBuy/SellNumber of SharesAverage Share PriceTotal TransactionShares Held After TransactionDetails
11/20/2025Alex NemiroffGeneral CounselSell25,130$193.09$4,852,351.7020,832View SEC Filing Icon  
11/20/2025Lauren MastrocolaInsiderSell13,600$192.08$2,612,288.0010,442View SEC Filing Icon  
11/14/2024Alex NemiroffGeneral CounselSell8,239$80.20$660,767.8010,301View SEC Filing Icon  
11/14/2024Lauren MastrocolaInsiderSell5,188$81.78$424,274.645,613View SEC Filing Icon  
10/5/2023Jill DesimoneDirectorBuy966$26.25$25,357.50966View SEC Filing Icon  
6/27/2023Marcio SouzaCEOBuy666$15.90$10,589.403,000View SEC Filing Icon  
3/24/2023Dean J MitchellDirectorBuy3,333$12.60$41,995.805,000View SEC Filing Icon  
3/23/2023Marcio SouzaCEOBuy2,333$12.90$30,095.7015,086View SEC Filing Icon  
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SEC Filings (Institutional Ownership Changes) for Praxis Precision Medicines (NASDAQ:PRAX)

67.84% of Praxis Precision Medicines stock is owned by institutions. Institutional ownership can be a sign of analyst confidence in the fundamentals of the stock.

Institutional Buying and Selling by Quarter

This chart shows the instiutional buying and selling at PRAX by year and by quarter.

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Praxis Precision Medicines Institutional Trading History

Reporting DateHedge FundShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
11/17/2025Jacobs Levy Equity Management Inc.13,898$0.74M0.0%-69.2%0.056%Search for SEC Filing on Google Icon
11/17/2025Woodline Partners LP417,669$22.14M0.1%+808.9%1.670%Search for SEC Filing on Google Icon
11/17/2025Dark Forest Capital Management LP21,684$1.15M0.0%N/A0.087%Search for SEC Filing on Google Icon
11/17/2025Alyeska Investment Group L.P.141,516$7.50M0.0%+13.2%0.566%Search for SEC Filing on Google Icon
11/17/2025Vivo Capital LLC198,895$10.54M0.8%+18.7%0.795%Search for SEC Filing on Google Icon
11/17/2025Velan Capital Investment Management LP132,805$7.04M6.6%-11.1%0.531%Search for SEC Filing on Google Icon
11/17/2025Quarry LP20,001$1.06M0.2%+316.7%0.080%Search for SEC Filing on Google Icon
11/17/2025Qube Research & Technologies Ltd57,304$3.04M0.0%N/A0.229%Search for SEC Filing on Google Icon
11/17/2025Prelude Capital Management LLC28,102$1.49M0.1%+41.2%0.112%Search for SEC Filing on Google Icon
11/17/2025MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.22,836$1.21M0.0%-4.3%0.091%Search for SEC Filing on Google Icon
11/17/2025HighVista Strategies LLC95,002$5.04M1.2%+41.2%0.380%Search for SEC Filing on Google Icon
11/17/2025Bank of America Corp DE482,861$25.59M0.0%+12.7%1.931%Search for SEC Filing on Google Icon
11/17/2025Algert Global LLC160,818$8.52M0.1%+483.3%0.643%Search for SEC Filing on Google Icon
11/14/2025Creative Planning6,660$0.35M0.0%+2.5%0.027%Search for SEC Filing on Google Icon
11/14/2025SummitTX Capital L.P.34,928$1.85M0.1%N/A0.140%Search for SEC Filing on Google Icon
11/14/2025Freestone Grove Partners LP8,269$0.44M0.0%N/A0.033%Search for SEC Filing on Google Icon
11/14/2025Deerfield Management Company L.P.840,851$44.57M0.7%+22.4%3.362%Search for SEC Filing on Google Icon
11/14/2025California State Teachers Retirement System18,583$0.99M0.0%+13.7%0.074%Search for SEC Filing on Google Icon
11/14/2025Acuta Capital Partners LLC49,751$2.64M2.7%-32.8%0.199%Search for SEC Filing on Google Icon
11/14/2025UBS AM A Distinct Business Unit of UBS Asset Management Americas LLC23,756$1.26M0.0%-75.5%0.095%Search for SEC Filing on Google Icon
11/14/2025Two Sigma Investments LP5,508$0.29M0.0%-15.4%0.022%Search for SEC Filing on Google Icon
11/14/2025B Group Inc.31,500$1.67M1.3%-10.0%0.126%Search for SEC Filing on Google Icon
11/13/2025PCG Wealth Advisors LLC14,483$0.77M0.2%N/A0.058%Search for SEC Filing on Google Icon
11/13/2025Kennedy Capital Management LLC76,218$4.04M0.1%+8.2%0.305%Search for SEC Filing on Google Icon
11/13/2025UBS Group AG96,812$5.13M0.0%+128.7%0.387%Search for SEC Filing on Google Icon
11/13/2025BNP Paribas Financial Markets4,385$0.23M0.0%+114.2%0.018%Search for SEC Filing on Google Icon
11/13/2025Legal & General Group Plc16,824$0.89M0.0%+0.9%0.067%Search for SEC Filing on Google Icon
11/13/2025Swiss National Bank35,500$1.88M0.0%+15.3%0.142%Search for SEC Filing on Google Icon
11/13/2025Russell Investments Group Ltd.4,404$0.23M0.0%+1,668.7%0.018%Search for SEC Filing on Google Icon
11/13/2025First Trust Advisors LP28,966$1.54M0.0%N/A0.116%Search for SEC Filing on Google Icon
11/13/2025Knott David M Jr28,000$1.48M0.6%N/A0.112%Search for SEC Filing on Google Icon
11/12/2025Barclays PLC76,637$4.06M0.0%-13.6%0.306%Search for SEC Filing on Google Icon
11/12/2025Dimensional Fund Advisors LP37,414$1.98M0.0%N/A0.150%Search for SEC Filing on Google Icon
11/12/2025Rafferty Asset Management LLC37,573$1.99M0.0%+51.5%0.150%Search for SEC Filing on Google Icon
11/12/2025Intech Investment Management LLC7,754$0.41M0.0%-11.1%0.031%Search for SEC Filing on Google Icon
11/10/2025TD Asset Management Inc40,884$2.17M0.0%-36.1%0.163%Search for SEC Filing on Google Icon
11/10/2025Ameritas Investment Partners Inc.1,519$81K0.0%-10.1%0.006%Search for SEC Filing on Google Icon
11/10/2025China Universal Asset Management Co. Ltd.3,689$0.20M0.0%-9.8%0.015%Search for SEC Filing on Google Icon
11/7/2025Readystate Asset Management LP109,177$5.79M0.2%N/A0.516%Search for SEC Filing on Google Icon
11/7/2025GSA Capital Partners LLP5,740$0.30M0.0%-52.2%0.027%Search for SEC Filing on Google Icon
11/7/2025Vanguard Group Inc.1,267,286$67.17M0.0%+4.2%5.986%Search for SEC Filing on Google Icon
11/7/2025JPMorgan Chase & Co.26,208$1.39M0.0%+88.0%0.124%Search for SEC Filing on Google Icon
11/6/2025Rhumbline Advisers26,794$1.42M0.0%-2.0%0.127%Search for SEC Filing on Google Icon
11/6/2025Profund Advisors LLC8,079$0.43M0.0%+53.6%0.038%Search for SEC Filing on Google Icon
11/6/2025ProShare Advisors LLC3,826$0.20M0.0%N/A0.018%Search for SEC Filing on Google Icon
11/6/2025Candriam S.C.A.62,866$3.33M0.0%-1.3%0.297%Search for SEC Filing on Google Icon
11/5/2025Alps Advisors Inc.10,424$0.55M0.0%-5.2%0.049%Search for SEC Filing on Google Icon
11/3/2025AlphaQuest LLC1,999$0.11M0.0%+1,623.3%0.009%Search for SEC Filing on Google Icon
11/3/2025Arizona State Retirement System5,417$0.29M0.0%N/A0.026%Search for SEC Filing on Google Icon
11/3/2025Coastal Bridge Advisors LLC3,846$0.20M0.0%N/A0.018%Search for SEC Filing on Google Icon
11/3/2025Phoenix Financial Ltd.6,817$0.36M0.0%N/A0.032%Search for SEC Filing on Google Icon
10/31/2025Y Intercept Hong Kong Ltd32,186$1.71M0.0%N/A0.152%Search for SEC Filing on Google Icon
10/23/2025Nisa Investment Advisors LLC7,129$0.38M0.0%+1,033.4%0.034%Search for SEC Filing on Google Icon
10/23/2025SG Americas Securities LLC13,496$0.72M0.0%N/A0.064%Search for SEC Filing on Google Icon
10/23/2025KLP Kapitalforvaltning AS4,000$0.21M0.0%+42.9%0.019%Search for SEC Filing on Google Icon
10/20/2025VIRGINIA RETIREMENT SYSTEMS ET Al3,900$0.21M0.0%N/A0.018%Search for SEC Filing on Google Icon
10/10/2025Congress Asset Management Co.30,439$1.61M0.0%N/A0.145%Search for SEC Filing on Google Icon
10/7/2025Assenagon Asset Management S.A.409,779$21.72M0.0%-32.2%1.947%Search for SEC Filing on Google Icon
8/15/2025Tower Research Capital LLC TRC 1,837$77K0.0%+24.3%0.009%Search for SEC Filing on Google Icon
8/15/2025Exome Asset Management LLC59,002$2.48M1.3%N/A0.280%Search for SEC Filing on Google Icon
8/15/2025Soleus Capital Management L.P.966,740$40.65M2.7%-15.2%4.593%Search for SEC Filing on Google Icon
8/15/2025Sofinnova Investments Inc.15,717$0.66M0.0%-90.0%0.075%Search for SEC Filing on Google Icon
8/15/2025Rafferty Asset Management LLC24,805$1.04M0.0%-15.2%0.118%Search for SEC Filing on Google Icon
8/15/2025Perceptive Advisors LLC752,921$31.66M2.8%-23.2%3.577%Search for SEC Filing on Google Icon
8/15/2025BNP Paribas Financial Markets2,047$86K0.0%-72.5%0.010%Search for SEC Filing on Google Icon
8/15/2025Brevan Howard Capital Management LP8,503$0.36M0.0%N/A0.040%Search for SEC Filing on Google Icon
8/15/2025Balyasny Asset Management L.P.369,254$15.53M0.0%-8.4%1.754%Search for SEC Filing on Google Icon
8/15/2025Adage Capital Partners GP L.L.C.1,974,585$83.03M0.1%+13.3%9.380%Search for SEC Filing on Google Icon
8/14/2025Acuta Capital Partners LLC74,087$3.12M4.3%-15.0%0.352%Search for SEC Filing on Google Icon
8/14/2025MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.23,873$1.01M0.0%+103.9%0.113%Search for SEC Filing on Google Icon
8/14/2025Caption Management LLC39,036$1.64M0.0%-49.8%0.185%Search for SEC Filing on Google Icon
8/14/2025The Manufacturers Life Insurance Company 56,131$2.36M0.0%+72.8%0.267%Search for SEC Filing on Google Icon
8/14/2025OCONNOR A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS LLC 21,892$0.92M0.0%-18.3%0.104%Search for SEC Filing on Google Icon
8/14/2025HighVista Strategies LLC67,288$2.83M1.0%+71.3%0.320%Search for SEC Filing on Google Icon
8/14/2025Stempoint Capital LP32,255$1.36M0.4%N/A0.153%Search for SEC Filing on Google Icon
8/14/2025Velan Capital Investment Management LP149,334$6.28M6.2%-19.3%0.709%Search for SEC Filing on Google Icon
8/14/2025B Group Inc.35,000$1.47M1.1%+84.2%0.166%Search for SEC Filing on Google Icon
8/14/2025Vivo Capital LLC167,600$7.05M0.7%N/A0.796%Search for SEC Filing on Google Icon
8/14/2025Maven Securities LTD5,000$0.21M0.0%N/A0.024%Search for SEC Filing on Google Icon
8/14/2025Cerity Partners LLC5,611$0.24M0.0%N/A0.027%Search for SEC Filing on Google Icon
8/13/2025Kennedy Capital Management LLC70,445$2.96M0.1%+7.9%0.335%Search for SEC Filing on Google Icon
8/13/2025Invesco Ltd.15,939$0.67M0.0%+36.5%0.076%Search for SEC Filing on Google Icon
8/13/2025Virtus Investment Advisers LLC2,088$88K0.0%-9.8%0.010%Search for SEC Filing on Google Icon
8/13/2025Norges Bank5,000$0.21M0.0%N/A0.024%Search for SEC Filing on Google Icon
8/13/2025Capital Fund Management S.A.24,292$1.02M0.0%N/A0.115%Search for SEC Filing on Google Icon
8/13/2025State Board of Administration of Florida Retirement System6,425$0.27M0.0%+6.4%0.031%Search for SEC Filing on Google Icon
8/12/2025Rhumbline Advisers27,341$1.15M0.0%+12.5%0.130%Search for SEC Filing on Google Icon
8/12/2025Legal & General Group Plc16,670$0.70M0.0%+15.7%0.079%Search for SEC Filing on Google Icon
8/12/2025JPMorgan Chase & Co.13,938$0.59M0.0%+21.4%0.066%Search for SEC Filing on Google Icon
8/12/2025Swiss National Bank30,800$1.30M0.0%+13.7%0.146%Search for SEC Filing on Google Icon
8/8/2025Creative Planning6,495$0.27M0.0%N/A0.031%Search for SEC Filing on Google Icon
8/8/2025Geode Capital Management LLC451,731$19M0.0%+8.1%2.146%Search for SEC Filing on Google Icon
8/7/2025Profund Advisors LLC5,261$0.22M0.0%-13.9%0.025%Search for SEC Filing on Google Icon
7/31/2025Nisa Investment Advisors LLC629$26K0.0%+88.3%0.003%Search for SEC Filing on Google Icon
7/28/2025TD Asset Management Inc63,938$2.69M0.0%+72.2%0.314%Search for SEC Filing on Google Icon
7/25/2025CWM LLC753$32K0.0%+877.9%0.004%Search for SEC Filing on Google Icon
7/24/2025Aberdeen Group plc214,056$9M0.0%+143.5%1.051%Search for SEC Filing on Google Icon
7/11/2025Assenagon Asset Management S.A.604,298$25.41M0.0%+19.1%2.967%Search for SEC Filing on Google Icon
6/27/2025Goldman Sachs Group Inc.177,264$6.71M0.0%-36.6%0.870%Search for SEC Filing on Google Icon
5/29/2025Rhumbline Advisers24,294$0.92M0.0%+6.7%0.119%Search for SEC Filing on Google Icon
Data available starting January 2016

See Full Table
Praxis Precision Medicines logo
Praxis Precision Medicines, Inc., a clinical-stage biopharmaceutical company, engages in the development of therapies for central nervous system disorders characterized by neuronal excitation-inhibition imbalance. It is developing ulixacaltamide, a small molecule inhibitor of T-type calcium channels that is in Phase III clinical trial for the treatment of essential tremor; PRAX-562 for the treatment of pediatric patients with developmental and epileptic encephalopathies (DEE); and PRAX-628 to treat focal epilepsy. The company also develops PRAX-222 for the treatment of pediatric patients with early-onset SCN2A-DEE; PRAX-020 to treat KCNT1 related epilepsies; PRAX-080 for the treatment of PCDH19; and PRAX-090 and PRAX-100 for SYNGAP1 and SCN2A-LoF. It has a license agreement with RogCon Inc.; a research collaboration and license agreement with Ionis Pharmaceuticals, Inc.; a strategic collaboration and license agreement with UCB Biopharma SRL; and collaboration with The Florey Institute to develop three novel ASOs. The company was incorporated in 2015 and is based in Boston, Massachusetts.
Read More on Praxis Precision Medicines

Today's Range

Now: $189.97
Low: $180.93
High: $199.53

50 Day Range

MA: $146.70
Low: $50.98
High: $201.00

52 Week Range

Now: $189.97
Low: $26.70
High: $206.71

Volume

964,760 shs

Average Volume

872,909 shs

Market Capitalization

$4.75 billion

P/E Ratio

N/A

Dividend Yield

N/A

Beta

2.95

Who are the company insiders with the largest holdings of Praxis Precision Medicines?

Praxis Precision Medicines' top insider investors include:
  1. Alex Nemiroff (General Counsel)
  2. Lauren Mastrocola (Insider)
Learn More about top insider investors at Praxis Precision Medicines.

Who are the major institutional investors of Praxis Precision Medicines?

Praxis Precision Medicines' top institutional investors include:
  1. Vanguard Group Inc. — 5.99%
  2. Deerfield Management Company L.P. — 3.36%
  3. Bank of America Corp DE — 1.93%
  4. Woodline Partners LP — 1.67%
  5. Assenagon Asset Management S.A. — 1.95%
  6. Vivo Capital LLC — 0.80%
Learn More about top institutional investors of Praxis Precision Medicines stock.

Which major investors are selling Praxis Precision Medicines stock?

In the last quarter, PRAX stock was sold by these institutional investors:
  1. Assenagon Asset Management S.A.
  2. UBS AM A Distinct Business Unit of UBS Asset Management Americas LLC
  3. Jacobs Levy Equity Management Inc.
  4. Acuta Capital Partners LLC
  5. TD Asset Management Inc
  6. Susquehanna International Group LLP
  7. Velan Capital Investment Management LP
  8. Barclays PLC
During the previous year, company insiders that have sold Praxis Precision Medicines company stock include:
  1. Alex Nemiroff (General Counsel)
  2. Lauren Mastrocola (Insider)
Learn More investors selling Praxis Precision Medicines stock.

Which major investors are buying Praxis Precision Medicines stock?

During the previous quarter, PRAX stock was bought by institutional investors including:
  1. Woodline Partners LP
  2. Deerfield Management Company L.P.
  3. Caption Management LLC
  4. Algert Global LLC
  5. Readystate Asset Management LP
  6. Qube Research & Technologies Ltd
  7. UBS Group AG
  8. Bank of America Corp DE