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PRAX Insider Trading

Insider Ownership Percentage: 3.00%
Insider Buying (Last 12 Months): $0.00
Insider Selling (Last 12 Months): $11,075,951.70

Praxis Precision Medicines Insider Trading History Chart

This chart shows the insider buying and selling history at Praxis Precision Medicines by year and by quarter.

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Praxis Precision Medicines Share Price & Price History

Current Price: $275.30
Price Change: ▼ Price Decrease of -10.63 (-3.72%)
As of 11/2/2026 11:24 AM ET

This chart shows the closing price history over time for PRAX up to the past year.

Skip Chart and Table DataPrice Data in Insider Trading History Table
Days: 30 | 90 | 365

Praxis Precision Medicines Insider Trading History

Transaction DateInsider NameTitleBuy/SellNumber of SharesAverage Share PriceTotal TransactionShares Held After TransactionDetails
6/24/2026Jill DesimoneDirectorSell11,600$311.32$3,611,312.002,337View SEC Filing Icon  
11/20/2025Alex NemiroffGeneral CounselSell25,130$193.09$4,852,351.7020,832View SEC Filing Icon  
11/20/2025Lauren MastrocolaInsiderSell13,600$192.08$2,612,288.0010,442View SEC Filing Icon  
11/14/2024Alex NemiroffGeneral CounselSell8,239$80.20$660,767.8010,301View SEC Filing Icon  
11/14/2024Lauren MastrocolaInsiderSell5,188$81.78$424,274.645,613View SEC Filing Icon  
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SEC Filings (Institutional Ownership Changes) for Praxis Precision Medicines (NASDAQ:PRAX)

67.84% of Praxis Precision Medicines stock is owned by institutions. Institutional ownership can be a sign of analyst confidence in the fundamentals of the stock.

Institutional Buying and Selling by Quarter

This chart shows the instiutional buying and selling at PRAX by year and by quarter.

Skip Institutional Buying and Selling Chart and Table DataRead Chart Data in Institutional Trading History Table

Praxis Precision Medicines Institutional Trading History

Reporting DateHedge FundShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
10/30/2026Provenance Wealth Advisors LLC439$0.13M0.0%N/A0.002%Search for SEC Filing on Google Icon
10/30/2026Factory Mutual Insurance Co.1,019$0.30M0.0%N/A0.004%Search for SEC Filing on Google Icon
10/29/2026Sumitomo Mitsui Trust Group Inc.1,016$0.30M0.0%N/A0.004%Search for SEC Filing on Google Icon
10/29/2026Mirae Asset Global Investments Co. Ltd.4,201$1.22M0.0%N/A0.015%Search for SEC Filing on Google Icon
10/29/2026Profund Advisors LLC6,764$1.97M0.1%+10.9%0.024%Search for SEC Filing on Google Icon
10/29/2026ProShare Advisors LLC4,124$1.20M0.0%-2.0%0.015%Search for SEC Filing on Google Icon
10/29/2026State of Wyoming2,022$0.59M0.0%-27.0%0.007%Search for SEC Filing on Google Icon
10/28/2026VIRGINIA RETIREMENT SYSTEMS ET Al7,940$2.31M0.0%-1.5%0.028%Search for SEC Filing on Google Icon
10/28/2026China Universal Asset Management Co. Ltd.5,094$1.43M0.1%+14.8%0.000%Search for SEC Filing on Google Icon
10/27/2026Moody Aldrich Partners LLC19,193$5.59M1.1%+0.7%0.069%Search for SEC Filing on Google Icon
10/26/2026Park Avenue Securities LLC826$0.24M0.0%N/A0.003%Search for SEC Filing on Google Icon
10/23/2026Sterling Capital Management LLC829$0.24M0.0%+842.0%0.003%Search for SEC Filing on Google Icon
10/23/2026Inspire Investing LLC1,724$0.50M0.0%N/A0.006%Search for SEC Filing on Google Icon
10/21/2026Nisa Investment Advisors LLC6,167$1.80M0.0%+0.9%0.022%Search for SEC Filing on Google Icon
10/20/2026Net Worth Advisory Group1,151$0.33M0.1%N/A0.004%Search for SEC Filing on Google Icon
10/17/2026IFP Advisors Inc183$53K0.0%+632.0%0.001%Search for SEC Filing on Google Icon
10/16/2026Eagle Bay Advisors LLC1,064$0.31M0.2%+11.3%0.004%Search for SEC Filing on Google Icon
10/13/2026Avior Wealth Management LLC780$0.23M0.0%N/A0.003%Search for SEC Filing on Google Icon
10/9/2026GAMMA Investing LLC432$0.13M0.0%+30.1%0.002%Search for SEC Filing on Google Icon
9/9/2026Integrated Wealth Concepts LLC114$38K0.0%N/A0.000%Search for SEC Filing on Google Icon
9/8/2026Arizona State Retirement System6,340$2.12M0.0%-2.1%0.023%Search for SEC Filing on Google Icon
9/8/2026Nykredit A S779$0.26M0.0%N/A0.003%Search for SEC Filing on Google Icon
8/25/2026VIRGINIA RETIREMENT SYSTEMS ET Al8,060$2.70M0.0%N/A0.029%Search for SEC Filing on Google Icon
8/23/2026Readystate Asset Management LP10,548$3.53M0.1%N/A0.038%Search for SEC Filing on Google Icon
8/22/2026Seven Fleet Capital Management LP7,540$2.52M0.4%N/A0.027%Search for SEC Filing on Google Icon
8/21/2026Nykredit A S779$0.26M0.0%N/A0.003%Search for SEC Filing on Google Icon
8/21/2026Velan Capital Investment Management LP88,781$29.72M18.0%-11.9%0.318%Search for SEC Filing on Google Icon
8/19/2026Wellington Management Group LLP125,867$42.14M0.0%-27.8%0.451%Search for SEC Filing on Google Icon
8/6/2026Bank of New York Mellon Corp85,376$28.58M0.0%N/A0.306%Search for SEC Filing on Google Icon
7/10/2026Handelsbanken Fonder AB9,840$3.29M0.0%N/A0.035%Search for SEC Filing on Google Icon
7/7/2026GAMMA Investing LLC332$0.11M0.0%+10.3%0.001%Search for SEC Filing on Google Icon
6/3/2026Parallel Advisors LLC124$40K0.0%+3,000.0%0.000%Search for SEC Filing on Google Icon
5/29/2026Perceptive Advisors LLC2,035,986$655.97M12.8%+2.0%7.303%Search for SEC Filing on Google Icon
5/26/2026Glenmede Trust Co. NA3,410$1.10M0.0%-45.8%0.012%Search for SEC Filing on Google Icon
5/21/2026CTC Alternative Strategies Ltd.925$0.30M0.7%N/A0.003%Search for SEC Filing on Google Icon
5/20/2026Vivo Capital LLC338,895$109.19M9.1%+3.0%1.216%Search for SEC Filing on Google Icon
5/19/2026Bank of America Corp DE534,604$172.24M0.0%+2.3%1.918%Search for SEC Filing on Google Icon
5/19/2026Stempoint Capital LP56,267$18.13M3.5%+167.1%0.202%Search for SEC Filing on Google Icon
5/19/2026Janus Henderson Group PLC3,458,863$1.11B0.5%+6.8%12.406%Search for SEC Filing on Google Icon
5/19/2026Ally Bridge Group NY LLC32,810$10.57M8.5%+65.0%0.118%Search for SEC Filing on Google Icon
5/18/2026Amundi1,802$0.58M0.0%+128.1%0.006%Search for SEC Filing on Google Icon
5/18/2026California State Teachers Retirement System27,477$8.85M0.0%+39.7%0.099%Search for SEC Filing on Google Icon
5/18/2026Royal Bank of Canada4,133$1.33M0.0%+22.4%0.015%Search for SEC Filing on Google Icon
5/18/2026Exome Asset Management LLC45,469$14.65M7.6%-21.8%0.163%Search for SEC Filing on Google Icon
5/16/2026The Manufacturers Life Insurance Company30,093$9.70M0.0%-9.6%0.108%Search for SEC Filing on Google Icon
5/16/2026Quantinno Capital Management LP3,320$1.07M0.0%+21.9%0.012%Search for SEC Filing on Google Icon
5/16/2026SummitTX Capital L.P.36,838$11.87M0.4%-11.5%0.132%Search for SEC Filing on Google Icon
5/16/2026ABS Direct Equity Fund LLC400$0.14M0.1%N/A0.001%Search for SEC Filing on Google Icon
5/16/2026Orbimed Advisors LLC172,500$55.58M1.0%+82.5%0.619%Search for SEC Filing on Google Icon
5/15/2026Affinity Asset Advisors LLC170,000$54.77M2.8%-8.1%0.610%Search for SEC Filing on Google Icon
5/14/2026Sei Investments Co.29,525$9.51M0.0%+86.9%0.106%Search for SEC Filing on Google Icon
5/13/2026First Trust Advisors LP33,335$10.74M0.0%-62.4%0.120%Search for SEC Filing on Google Icon
5/8/2026PNC Financial Services Group Inc.953$0.31M0.0%+33.5%0.003%Search for SEC Filing on Google Icon
5/7/2026Carl P. Sherr & Co. LLC972$0.31M0.1%+8.4%0.003%Search for SEC Filing on Google Icon
5/7/2026Dimensional Fund Advisors LP31,161$10.04M0.0%+32.4%0.112%Search for SEC Filing on Google Icon
5/7/2026Parallel Advisors LLC124$40K0.0%+3,000.0%0.000%Search for SEC Filing on Google Icon
5/7/2026KBC Group NV715$0.23M0.0%+5.8%0.003%Search for SEC Filing on Google Icon
5/7/2026Swiss National Bank46,700$15.05M0.0%+15.3%0.168%Search for SEC Filing on Google Icon
5/6/2026California Public Employees Retirement System42,163$13.58M0.0%N/A0.151%Search for SEC Filing on Google Icon
5/6/2026Allspring Global Investments Holdings LLC8,536$2.73M0.0%+392.8%0.031%Search for SEC Filing on Google Icon
5/5/2026Bank of New York Mellon Corp87,047$28.05M0.0%+11.7%0.313%Search for SEC Filing on Google Icon
5/4/2026Principal Financial Group Inc.1,153$0.37M0.0%+15.9%0.004%Search for SEC Filing on Google Icon
5/4/2026Chicago Partners Investment Group LLC833$0.28M0.0%N/A0.003%Search for SEC Filing on Google Icon
5/1/2026Fifth Third Bancorp3,589$1.16M0.0%N/A0.013%Search for SEC Filing on Google Icon
5/1/2026Candriam S.C.A.63,628$20.50M0.1%-42.5%0.228%Search for SEC Filing on Google Icon
4/30/2026Hsbc Holdings PLC1,634$0.52M0.0%+98.1%0.006%Search for SEC Filing on Google Icon
4/28/2026Abel Hall LLC1,392$0.45M0.1%+34.9%0.005%Search for SEC Filing on Google Icon
4/25/2026Strs Ohio3,600$1.16M0.0%+12.5%0.013%Search for SEC Filing on Google Icon
4/22/2026Pictet Asset Management Holding SA286,644$91.43M0.1%+19.1%1.029%Search for SEC Filing on Google Icon
4/22/2026Sterling Capital Management LLC804$0.26M0.0%-33.6%0.003%Search for SEC Filing on Google Icon
4/21/2026Pinnacle Wealth Management Advisory Group LLC744$0.24M0.0%N/A0.003%Search for SEC Filing on Google Icon
4/16/2026SG Americas Securities LLC852$0.28M0.0%-91.5%0.003%Search for SEC Filing on Google Icon
3/20/2026Hsbc Holdings PLC825$0.24M0.0%-92.6%0.003%Search for SEC Filing on Google Icon
2/26/2026Seven Fleet Capital Management LP2,700$0.80M0.6%N/A0.010%Search for SEC Filing on Google Icon
2/19/2026T. Rowe Price Investment Management Inc.276,392$81.46M0.1%N/A1.097%Search for SEC Filing on Google Icon
2/19/2026Invesco Ltd.77,088$22.72M0.0%+269.4%0.306%Search for SEC Filing on Google Icon
2/18/2026Mercer Global Advisors Inc. ADV1,212$0.36M0.0%N/A0.005%Search for SEC Filing on Google Icon
2/18/2026Mackenzie Financial Corp1,399$0.42M0.0%N/A0.006%Search for SEC Filing on Google Icon
2/18/2026Coastal Bridge Advisors LLC4,154$1.22M0.1%+8.0%0.016%Search for SEC Filing on Google Icon
2/18/2026KVP Capital Advisors LP42,900$12.64M12.2%N/A0.170%Search for SEC Filing on Google Icon
2/18/2026Ikarian Capital LLC86,581$25.52M2.0%-32.7%0.344%Search for SEC Filing on Google Icon
2/18/2026Virtus Investment Advisers LLC989$0.29M0.1%-60.9%0.004%Search for SEC Filing on Google Icon
2/18/2026Wellington Management Group LLP176,562$52.04M0.0%+188.3%0.701%Search for SEC Filing on Google Icon
2/18/2026SummitTX Capital L.P.41,629$12.27M0.4%+19.2%0.165%Search for SEC Filing on Google Icon
2/18/2026Readystate Asset Management LP36,792$10.84M0.4%-66.3%0.146%Search for SEC Filing on Google Icon
2/18/2026Orbimed Advisors LLC94,500$27.85M0.6%N/A0.375%Search for SEC Filing on Google Icon
2/18/2026Perceptive Advisors LLC1,995,986$588.30M10.5%+27.6%7.924%Search for SEC Filing on Google Icon
2/18/2026Man Group plc21,170$6.24M0.0%N/A0.084%Search for SEC Filing on Google Icon
2/18/2026Ishara Investments LP40,000$11.79M13.6%N/A0.159%Search for SEC Filing on Google Icon
2/18/2026Janus Henderson Group PLC3,240,086$954.83M0.4%+17.2%12.863%Search for SEC Filing on Google Icon
2/18/2026Cormorant Asset Management LP950,000$280M12.9%-5.0%3.771%Search for SEC Filing on Google Icon
2/18/2026Artia Global Partners LP2,500$0.74M0.1%N/A0.010%Search for SEC Filing on Google Icon
2/18/2026Baker BROS. Advisors LP1,126,488$332.02M1.9%+63.4%4.472%Search for SEC Filing on Google Icon
2/18/2026Boothbay Fund Management LLC20,974$6.18M0.1%-78.2%0.083%Search for SEC Filing on Google Icon
2/18/2026ACT Capital Management LLC700$0.21M0.2%N/A0.003%Search for SEC Filing on Google Icon
2/17/2026Logos Global Management LP375,000$110.53M6.7%+200.0%1.489%Search for SEC Filing on Google Icon
2/17/2026ADAR1 Capital Management LLC1,500$0.44M0.0%N/A0.006%Search for SEC Filing on Google Icon
2/17/2026Burkehill Global Management LP25,000$7.37M0.5%N/A0.099%Search for SEC Filing on Google Icon
2/17/2026AQR Capital Management LLC28,828$8.50M0.0%+31.6%0.114%Search for SEC Filing on Google Icon
2/17/2026Abel Hall LLC1,032$0.30M0.1%N/A0.004%Search for SEC Filing on Google Icon
Data available starting January 2016

See Full Table
Praxis Precision Medicines logo
Praxis Precision Medicines, Inc., a clinical-stage biopharmaceutical company, engages in the development of therapies for central nervous system disorders characterized by neuronal excitation-inhibition imbalance. It is developing ulixacaltamide, a small molecule inhibitor of T-type calcium channels that is in Phase III clinical trial for the treatment of essential tremor; PRAX-562 for the treatment of pediatric patients with developmental and epileptic encephalopathies (DEE); and PRAX-628 to treat focal epilepsy. The company also develops PRAX-222 for the treatment of pediatric patients with early-onset SCN2A-DEE; PRAX-020 to treat KCNT1 related epilepsies; PRAX-080 for the treatment of PCDH19; and PRAX-090 and PRAX-100 for SYNGAP1 and SCN2A-LoF. It has a license agreement with RogCon Inc.; a research collaboration and license agreement with Ionis Pharmaceuticals, Inc.; a strategic collaboration and license agreement with UCB Biopharma SRL; and collaboration with The Florey Institute to develop three novel ASOs. The company was incorporated in 2015 and is based in Boston, Massachusetts.
Read More on Praxis Precision Medicines

Today's Range

Now: $275.30
Low: $274.37
High: $294.95

50 Day Range

MA: $301.28
Low: $239.02
High: $377.37

52 Week Range

Now: $275.30
Low: $154.45
High: $392.70

Volume

54,383 shs

Average Volume

467,131 shs

Market Capitalization

$7.69 billion

P/E Ratio

N/A

Dividend Yield

N/A

Beta

2.85

Who are the company insiders with the largest holdings of Praxis Precision Medicines?

Praxis Precision Medicines' top insider investors include:
  1. Alex Nemiroff (General Counsel)
  2. Marcio Souza (CEO)
  3. Lauren Mastrocola (Insider)
  4. Dean J Mitchell (Director)
  5. Timothy Edwin Kelly (CFO)
  6. Jill Desimone (Director)
  7. Parallel Master Fund LP Bsof (Major Shareholder)
Learn More about top insider investors at Praxis Precision Medicines.

Who are the major institutional investors of Praxis Precision Medicines?

Praxis Precision Medicines' top institutional investors include:
  1. Moody Aldrich Partners LLC — 0.07%
  2. VIRGINIA RETIREMENT SYSTEMS ET Al — 0.03%
  3. Profund Advisors LLC — 0.02%
  4. Nisa Investment Advisors LLC — 0.02%
  5. China Universal Asset Management Co. Ltd. — 0.00%
  6. Mirae Asset Global Investments Co. Ltd. — 0.02%
Learn More about top institutional investors of Praxis Precision Medicines stock.

Which major investors are selling Praxis Precision Medicines stock?

In the last quarter, PRAX stock was sold by these institutional investors:
  1. State of Wyoming
  2. VIRGINIA RETIREMENT SYSTEMS ET Al
  3. ProShare Advisors LLC
During the previous year, company insiders that have sold Praxis Precision Medicines company stock include:
  1. Alex Nemiroff (General Counsel)
  2. Lauren Mastrocola (Insider)
  3. Jill Desimone (Director)
Learn More investors selling Praxis Precision Medicines stock.

Which major investors are buying Praxis Precision Medicines stock?

During the previous quarter, PRAX stock was bought by institutional investors including:
  1. Mirae Asset Global Investments Co. Ltd.
  2. Inspire Investing LLC
  3. Net Worth Advisory Group
  4. Factory Mutual Insurance Co.
  5. Sumitomo Mitsui Trust Group Inc.
  6. Park Avenue Securities LLC
  7. Avior Wealth Management LLC
  8. Sterling Capital Management LLC

Praxis Precision Medicines Active Insiders

Marcio Souza
Marcio Souza (Age 47)
CEO
Jill Desimone
Jill Desimone
Director
1 recent trades
Alex Nemiroff
Alex Nemiroff (Age 47)
General Counsel
Lauren Mastrocola
Lauren Mastrocola
Insider