InsiderTrades.com logo

PRAX Insider Trading

Insider Ownership Percentage: 2.70%
Insider Buying (Last 12 Months): $0.00
Insider Selling (Last 12 Months): $7,464,639.70

Praxis Precision Medicines Insider Trading History Chart

This chart shows the insider buying and selling history at Praxis Precision Medicines by year and by quarter.

Skip ChartChart Data in Insider Trading History Table

Praxis Precision Medicines Share Price & Price History

Current Price: $333.30
Price Change: ▼ Price Decrease of -4.31 (-1.28%)
As of 05/5/2026 04:00 PM ET

This chart shows the closing price history over time for PRAX up to the past year.

Skip Chart and Table DataPrice Data in Insider Trading History Table
Days: 30 | 90 | 365

Praxis Precision Medicines Insider Trading History

Transaction DateInsider NameTitleBuy/SellNumber of SharesAverage Share PriceTotal TransactionShares Held After TransactionDetails
11/20/2025Alex NemiroffGeneral CounselSell25,130$193.09$4,852,351.7020,832View SEC Filing Icon  
11/20/2025Lauren MastrocolaInsiderSell13,600$192.08$2,612,288.0010,442View SEC Filing Icon  
11/14/2024Alex NemiroffGeneral CounselSell8,239$80.20$660,767.8010,301View SEC Filing Icon  
11/14/2024Lauren MastrocolaInsiderSell5,188$81.78$424,274.645,613View SEC Filing Icon  
10/5/2023Jill DesimoneDirectorBuy966$26.25$25,357.50966View SEC Filing Icon  
6/27/2023Marcio SouzaCEOBuy666$15.90$10,589.403,000View SEC Filing Icon  
See Full Table

SEC Filings (Institutional Ownership Changes) for Praxis Precision Medicines (NASDAQ:PRAX)

67.84% of Praxis Precision Medicines stock is owned by institutions. Institutional ownership can be a sign of analyst confidence in the fundamentals of the stock.

Institutional Buying and Selling by Quarter

This chart shows the instiutional buying and selling at PRAX by year and by quarter.

Skip Institutional Buying and Selling Chart and Table DataRead Chart Data in Institutional Trading History Table

Praxis Precision Medicines Institutional Trading History

Reporting DateHedge FundShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
5/5/2026Bank of New York Mellon Corp87,047$28.05M0.0%+11.7%0.313%Search for SEC Filing on Google Icon
5/4/2026Principal Financial Group Inc.1,153$0.37M0.0%+15.9%0.004%Search for SEC Filing on Google Icon
5/4/2026Chicago Partners Investment Group LLC833$0.28M0.0%N/A0.003%Search for SEC Filing on Google Icon
5/1/2026Fifth Third Bancorp3,589$1.16M0.0%N/A0.013%Search for SEC Filing on Google Icon
5/1/2026Candriam S.C.A.63,628$20.50M0.1%-42.5%0.228%Search for SEC Filing on Google Icon
4/30/2026Hsbc Holdings PLC1,634$0.52M0.0%+98.1%0.006%Search for SEC Filing on Google Icon
4/28/2026Abel Hall LLC1,392$0.45M0.1%+34.9%0.005%Search for SEC Filing on Google Icon
4/25/2026Strs Ohio3,600$1.16M0.0%+12.5%0.013%Search for SEC Filing on Google Icon
4/22/2026Pictet Asset Management Holding SA286,644$91.43M0.1%+19.1%1.029%Search for SEC Filing on Google Icon
4/22/2026Sterling Capital Management LLC804$0.26M0.0%-33.6%0.003%Search for SEC Filing on Google Icon
4/21/2026Pinnacle Wealth Management Advisory Group LLC744$0.24M0.0%N/A0.003%Search for SEC Filing on Google Icon
4/16/2026SG Americas Securities LLC852$0.28M0.0%-91.5%0.003%Search for SEC Filing on Google Icon
3/20/2026Hsbc Holdings PLC825$0.24M0.0%-92.6%0.003%Search for SEC Filing on Google Icon
2/26/2026Seven Fleet Capital Management LP2,700$0.80M0.6%N/A0.010%Search for SEC Filing on Google Icon
2/19/2026T. Rowe Price Investment Management Inc.276,392$81.46M0.1%N/A1.097%Search for SEC Filing on Google Icon
2/19/2026Invesco Ltd.77,088$22.72M0.0%+269.4%0.306%Search for SEC Filing on Google Icon
2/18/2026Mercer Global Advisors Inc. ADV1,212$0.36M0.0%N/A0.005%Search for SEC Filing on Google Icon
2/18/2026Mackenzie Financial Corp1,399$0.42M0.0%N/A0.006%Search for SEC Filing on Google Icon
2/18/2026Coastal Bridge Advisors LLC4,154$1.22M0.1%+8.0%0.016%Search for SEC Filing on Google Icon
2/18/2026KVP Capital Advisors LP42,900$12.64M12.2%N/A0.170%Search for SEC Filing on Google Icon
2/18/2026Ikarian Capital LLC86,581$25.52M2.0%-32.7%0.344%Search for SEC Filing on Google Icon
2/18/2026Virtus Investment Advisers LLC989$0.29M0.1%-60.9%0.004%Search for SEC Filing on Google Icon
2/18/2026Wellington Management Group LLP176,562$52.04M0.0%+188.3%0.701%Search for SEC Filing on Google Icon
2/18/2026SummitTX Capital L.P.41,629$12.27M0.4%+19.2%0.165%Search for SEC Filing on Google Icon
2/18/2026Readystate Asset Management LP36,792$10.84M0.4%-66.3%0.146%Search for SEC Filing on Google Icon
2/18/2026Orbimed Advisors LLC94,500$27.85M0.6%N/A0.375%Search for SEC Filing on Google Icon
2/18/2026Perceptive Advisors LLC1,995,986$588.30M10.5%+27.6%7.924%Search for SEC Filing on Google Icon
2/18/2026Man Group plc21,170$6.24M0.0%N/A0.084%Search for SEC Filing on Google Icon
2/18/2026Ishara Investments LP40,000$11.79M13.6%N/A0.159%Search for SEC Filing on Google Icon
2/18/2026Janus Henderson Group PLC3,240,086$954.83M0.4%+17.2%12.863%Search for SEC Filing on Google Icon
2/18/2026Cormorant Asset Management LP950,000$280M12.9%-5.0%3.771%Search for SEC Filing on Google Icon
2/18/2026Artia Global Partners LP2,500$0.74M0.1%N/A0.010%Search for SEC Filing on Google Icon
2/18/2026Baker BROS. Advisors LP1,126,488$332.02M1.9%+63.4%4.472%Search for SEC Filing on Google Icon
2/18/2026Boothbay Fund Management LLC20,974$6.18M0.1%-78.2%0.083%Search for SEC Filing on Google Icon
2/18/2026ACT Capital Management LLC700$0.21M0.2%N/A0.003%Search for SEC Filing on Google Icon
2/17/2026Logos Global Management LP375,000$110.53M6.7%+200.0%1.489%Search for SEC Filing on Google Icon
2/17/2026ADAR1 Capital Management LLC1,500$0.44M0.0%N/A0.006%Search for SEC Filing on Google Icon
2/17/2026Burkehill Global Management LP25,000$7.37M0.5%N/A0.099%Search for SEC Filing on Google Icon
2/17/2026AQR Capital Management LLC28,828$8.50M0.0%+31.6%0.114%Search for SEC Filing on Google Icon
2/17/2026Abel Hall LLC1,032$0.30M0.1%N/A0.004%Search for SEC Filing on Google Icon
2/17/2026Ally Bridge Group NY LLC19,882$5.86M6.1%-80.1%0.079%Search for SEC Filing on Google Icon
2/17/2026RA Capital Management L.P.373,787$110.17M1.1%N/A1.484%Search for SEC Filing on Google Icon
2/17/2026ArrowMark Colorado Holdings LLC30,000$8.84M0.2%N/A0.119%Search for SEC Filing on Google Icon
2/17/2026Trexquant Investment LP8,331$2.46M0.0%-6.4%0.033%Search for SEC Filing on Google Icon
2/17/2026Amundi790$0.23M0.0%N/A0.003%Search for SEC Filing on Google Icon
2/17/2026Orbis Allan Gray Ltd1,255,162$369.95M1.6%N/A4.983%Search for SEC Filing on Google Icon
2/17/2026Price T Rowe Associates Inc. MD785,987$231.66M0.0%-21.7%3.120%Search for SEC Filing on Google Icon
2/17/2026T. Rowe Price Investment Management Inc.18,018$5.31M0.0%N/A0.072%Search for SEC Filing on Google Icon
2/17/2026Integral Health Asset Management LLC40,000$11.79M0.6%N/A0.159%Search for SEC Filing on Google Icon
2/17/2026Adage Capital Partners GP L.L.C.965,313$284.52M0.4%-59.3%3.832%Search for SEC Filing on Google Icon
2/17/2026California State Teachers Retirement System19,671$5.80M0.0%+5.9%0.078%Search for SEC Filing on Google Icon
2/17/2026Russell Investments Group Ltd.20,612$6.08M0.0%+368.0%0.082%Search for SEC Filing on Google Icon
2/17/2026B Group Inc.33,237$9.80M7.2%+5.5%0.132%Search for SEC Filing on Google Icon
2/17/2026Atom Investors LP16,487$4.86M0.4%N/A0.065%Search for SEC Filing on Google Icon
2/17/2026State of Wisconsin Investment Board15,231$4.49M0.0%+68.6%0.060%Search for SEC Filing on Google Icon
2/17/2026Royal Bank of Canada3,378$1M0.0%-14.6%0.013%Search for SEC Filing on Google Icon
2/17/2026Opal Capital LLC996$0.32M0.1%N/A0.004%Search for SEC Filing on Google Icon
2/16/2026Squarepoint Ops LLC1,890$0.56M0.0%N/A0.008%Search for SEC Filing on Google Icon
2/16/2026Sofinnova Investments Inc.125,722$37.06M1.5%-27.3%0.499%Search for SEC Filing on Google Icon
2/16/2026Public Employees Retirement Association of Colorado2,390$0.70M0.0%+1,001.4%0.009%Search for SEC Filing on Google Icon
2/16/2026MML Investors Services LLC864$0.26M0.0%N/A0.003%Search for SEC Filing on Google Icon
2/16/2026First Turn Management LLC35,749$10.54M1.2%N/A0.142%Search for SEC Filing on Google Icon
2/16/2026Healthcare of Ontario Pension Plan Trust Fund4,587$1.35M0.0%N/A0.018%Search for SEC Filing on Google Icon
2/16/2026Eventide Asset Management LLC67,100$19.78M0.3%N/A0.266%Search for SEC Filing on Google Icon
2/16/2026Barclays PLC530,751$156.43M0.0%+592.6%2.107%Search for SEC Filing on Google Icon
2/13/2026Kestra Advisory Services LLC1,180$0.35M0.0%N/A0.005%Search for SEC Filing on Google Icon
2/13/2026Marshall Wace LLP69,242$20.41M0.0%+1.6%0.275%Search for SEC Filing on Google Icon
2/13/2026The Manufacturers Life Insurance Company 33,291$9.86M0.0%-7.1%0.132%Search for SEC Filing on Google Icon
2/13/2026Quinn Opportunity Partners LLC2,000$0.59M0.0%N/A0.008%Search for SEC Filing on Google Icon
2/13/2026Walleye Capital LLC3,587$1.06M0.0%N/A0.014%Search for SEC Filing on Google Icon
2/13/2026Affinity Asset Advisors LLC185,000$54.53M3.1%N/A0.734%Search for SEC Filing on Google Icon
2/13/2026Quarry LP4,000$1.18M0.2%-80.0%0.016%Search for SEC Filing on Google Icon
2/13/2026Vivo Capital LLC328,895$96.94M6.3%+65.4%1.306%Search for SEC Filing on Google Icon
2/13/2026Exome Asset Management LLC58,122$17.13M8.2%-48.1%0.231%Search for SEC Filing on Google Icon
2/13/2026Morgan Stanley889,889$262.29M0.0%+38.3%3.533%Search for SEC Filing on Google Icon
2/13/2026Jacobs Levy Equity Management Inc.10,140$2.99M0.0%-27.0%0.040%Search for SEC Filing on Google Icon
2/13/2026Public Sector Pension Investment Board3,297$0.97M0.0%N/A0.013%Search for SEC Filing on Google Icon
2/13/2026Rafferty Asset Management LLC22,240$6.56M0.0%-40.8%0.088%Search for SEC Filing on Google Icon
2/13/2026First Trust Advisors LP88,704$26.15M0.0%+206.2%0.352%Search for SEC Filing on Google Icon
2/13/2026Alyeska Investment Group L.P.74,376$21.92M0.1%-47.4%0.295%Search for SEC Filing on Google Icon
2/13/2026Velan Capital Investment Management LP100,781$29.70M17.2%-24.1%0.400%Search for SEC Filing on Google Icon
2/13/2026Charles Schwab Investment Management Inc.198,301$58.45M0.0%+22.7%0.787%Search for SEC Filing on Google Icon
2/13/2026Police & Firemen s Retirement System of New Jersey6,057$1.79M0.0%+23.2%0.024%Search for SEC Filing on Google Icon
2/13/2026State Street Corp882,215$260.02M0.0%-2.7%3.502%Search for SEC Filing on Google Icon
2/13/2026Ieq Capital LLC815$0.24M0.0%N/A0.003%Search for SEC Filing on Google Icon
2/13/2026Martingale Asset Management L P1,056$0.31M0.0%N/A0.004%Search for SEC Filing on Google Icon
2/13/2026UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC35,288$10.40M0.0%+48.5%0.140%Search for SEC Filing on Google Icon
2/13/2026Wells Fargo & Company MN25,235$7.44M0.0%+85.5%0.100%Search for SEC Filing on Google Icon
2/13/2026Lord Abbett & CO. LLC30,756$9.07M0.0%N/A0.122%Search for SEC Filing on Google Icon
2/12/2026Soleus Capital Management L.P.362,966$106.98M3.9%-57.8%1.441%Search for SEC Filing on Google Icon
2/12/2026Brooklyn Investment Group2,179$0.66M0.0%N/A0.009%Search for SEC Filing on Google Icon
2/12/2026Orion Porfolio Solutions LLC1,985$0.59M0.0%N/A0.008%Search for SEC Filing on Google Icon
2/12/2026MetLife Investment Management LLC12,424$3.66M0.0%+18.1%0.049%Search for SEC Filing on Google Icon
2/12/2026Cibc World Markets Corp1,490$0.44M0.0%N/A0.006%Search for SEC Filing on Google Icon
2/12/2026Commonwealth Equity Services LLC745$0.22M0.0%N/A0.003%Search for SEC Filing on Google Icon
2/12/2026State Board of Administration of Florida Retirement System5,806$1.71M0.0%-9.6%0.023%Search for SEC Filing on Google Icon
2/12/2026StoneX Group Inc.1,766$0.52M0.0%N/A0.007%Search for SEC Filing on Google Icon
2/12/2026Renaissance Technologies LLC66,230$19.52M0.0%N/A0.263%Search for SEC Filing on Google Icon
2/12/2026Dimensional Fund Advisors LP23,543$6.94M0.0%-37.1%0.093%Search for SEC Filing on Google Icon
2/12/2026EntryPoint Capital LLC887$0.26M0.1%N/A0.004%Search for SEC Filing on Google Icon
Data available starting January 2016

See Full Table
Praxis Precision Medicines logo
Praxis Precision Medicines, Inc., a clinical-stage biopharmaceutical company, engages in the development of therapies for central nervous system disorders characterized by neuronal excitation-inhibition imbalance. It is developing ulixacaltamide, a small molecule inhibitor of T-type calcium channels that is in Phase III clinical trial for the treatment of essential tremor; PRAX-562 for the treatment of pediatric patients with developmental and epileptic encephalopathies (DEE); and PRAX-628 to treat focal epilepsy. The company also develops PRAX-222 for the treatment of pediatric patients with early-onset SCN2A-DEE; PRAX-020 to treat KCNT1 related epilepsies; PRAX-080 for the treatment of PCDH19; and PRAX-090 and PRAX-100 for SYNGAP1 and SCN2A-LoF. It has a license agreement with RogCon Inc.; a research collaboration and license agreement with Ionis Pharmaceuticals, Inc.; a strategic collaboration and license agreement with UCB Biopharma SRL; and collaboration with The Florey Institute to develop three novel ASOs. The company was incorporated in 2015 and is based in Boston, Massachusetts.
Read More on Praxis Precision Medicines

Today's Range

Now: $333.30
Low: $324.32
High: $344.99

50 Day Range

MA: $318.06
Low: $276.44
High: $347.55

52 Week Range

Now: $333.30
Low: $34.89
High: $356.00

Volume

514,589 shs

Average Volume

388,244 shs

Market Capitalization

$9.29 billion

P/E Ratio

N/A

Dividend Yield

N/A

Beta

2.76

Who are the company insiders with the largest holdings of Praxis Precision Medicines?

Praxis Precision Medicines' top insider investors include:
  1. Alex Nemiroff (General Counsel)
  2. Marcio Souza (CEO)
  3. Lauren Mastrocola (Insider)
  4. Dean J Mitchell (Director)
  5. Timothy Edwin Kelly (CFO)
  6. Jill Desimone (Director)
  7. Parallel Master Fund LP Bsof (Major Shareholder)
Learn More about top insider investors at Praxis Precision Medicines.

Who are the major institutional investors of Praxis Precision Medicines?

Praxis Precision Medicines' top institutional investors include:
  1. Pictet Asset Management Holding SA — 1.03%
  2. Candriam S.C.A. — 0.23%
  3. Strs Ohio — 0.01%
  4. Fifth Third Bancorp — 0.01%
  5. Hsbc Holdings PLC — 0.01%
  6. Abel Hall LLC — 0.00%
Learn More about top institutional investors of Praxis Precision Medicines stock.

Which major investors are selling Praxis Precision Medicines stock?

In the last quarter, PRAX stock was sold by these institutional investors:
  1. Candriam S.C.A.
  2. SG Americas Securities LLC
  3. Sterling Capital Management LLC
During the previous year, company insiders that have sold Praxis Precision Medicines company stock include:
  1. Alex Nemiroff (General Counsel)
  2. Lauren Mastrocola (Insider)
Learn More investors selling Praxis Precision Medicines stock.

Which major investors are buying Praxis Precision Medicines stock?

During the previous quarter, PRAX stock was bought by institutional investors including:
  1. Pictet Asset Management Holding SA
  2. Fifth Third Bancorp
  3. Chicago Partners Investment Group LLC
  4. Hsbc Holdings PLC
  5. Pinnacle Wealth Management Advisory Group LLC
  6. Strs Ohio
  7. Abel Hall LLC
  8. Principal Financial Group Inc.

Praxis Precision Medicines Active Insiders

Marcio Souza
Marcio Souza (Age 47)
CEO
Jill Desimone
Jill Desimone
Director
Alex Nemiroff
Alex Nemiroff (Age 47)
General Counsel
1 recent trades
Lauren Mastrocola
Lauren Mastrocola
Insider
1 recent trades