InsiderTrades.com logo

ZYME Insider Trading

Insider Ownership Percentage: 33.51%
Insider Buying (Last 12 Months): $25,157,739.97
Insider Selling (Last 12 Months): $1,336,846.92

Zymeworks Insider Trading History Chart

This chart shows the insider buying and selling history at Zymeworks by year and by quarter.

Skip ChartChart Data in Insider Trading History Table

Zymeworks Share Price & Price History

Current Price: $26.52
Price Change: ▲ Price Increase of +0.3 (1.14%)
As of 12/4/2025 05:00 PM ET

This chart shows the closing price history over time for ZYME up to the past year.

Skip Chart and Table DataPrice Data in Insider Trading History Table
Days: 30 | 90 | 365

Zymeworks Insider Trading History

Transaction DateInsider NameTitleBuy/SellNumber of SharesAverage Share PriceTotal TransactionShares Held After TransactionDetails
5/19/2025Ecor1 Capital, LlcDirectorBuy5,919$11.78$69,725.8217,883,908View SEC Filing Icon  
5/15/2025Ecor1 Capital, LlcDirectorBuy49,502$11.43$565,807.8617,877,989View SEC Filing Icon  
4/16/2025Ecor1 Capital, LlcDirectorBuy73,953$11.16$825,315.4817,773,727View SEC Filing Icon  
4/4/2025Ecor1 Capital, LlcDirectorBuy196,438$11.17$2,194,212.4617,699,774View SEC Filing Icon  
4/2/2025Ecor1 Capital, LlcDirectorBuy74,360$11.85$881,166.0017,382,566View SEC Filing Icon  
3/31/2025Ecor1 Capital, LlcDirectorBuy4,397$11.75$51,664.7517,259,548View SEC Filing Icon  
3/26/2025Ecor1 Capital, LlcDirectorBuy43,848$12.24$536,699.5217,255,151View SEC Filing Icon  
3/24/2025Ecor1 Capital, LlcDirectorBuy22,689$13.08$296,772.1217,157,802View SEC Filing Icon  
3/21/2025Ecor1 Capital, LlcDirectorBuy31,033$12.78$396,601.7417,135,113View SEC Filing Icon  
3/19/2025Ecor1 Capital, LlcDirectorBuy58,306$12.64$736,987.8417,030,604View SEC Filing Icon  
3/17/2025Ecor1 Capital, LlcDirectorBuy56,277$12.23$688,267.7116,858,418View SEC Filing Icon  
3/13/2025Ecor1 Capital, LlcDirectorBuy468,356$12.48$5,845,082.8816,802,141View SEC Filing Icon  
3/11/2025Ecor1 Capital, LlcDirectorBuy320,690$11.49$3,684,728.1016,040,851View SEC Filing Icon  
1/17/2025Ecor1 Capital, LlcDirectorBuy19,748$13.87$273,904.7615,720,161View SEC Filing Icon  
1/15/2025Ecor1 Capital, LlcDirectorBuy39,029$14.01$546,796.2915,578,732View SEC Filing Icon  
1/13/2025Ecor1 Capital, LlcDirectorBuy74,125$13.39$992,533.7515,485,203View SEC Filing Icon  
1/10/2025Ecor1 Capital, LlcDirectorBuy204,098$13.13$2,679,806.7415,411,078View SEC Filing Icon  
1/8/2025Ecor1 Capital, LlcDirectorBuy21,021$14.07$295,765.4715,206,980View SEC Filing Icon  
1/6/2025Jeffrey T. L. SmithEVPSell11,110$14.92$165,761.208,890View SEC Filing Icon  
1/6/2025Kenneth GalbraithCEOSell57,291$14.92$854,781.7247,543View SEC Filing Icon  
1/6/2025Paul Andrew MooreInsiderSell21,200$14.92$316,304.0014,741View SEC Filing Icon  
1/2/2025Ecor1 Capital, LlcDirectorBuy157,880$14.78$2,333,466.4015,185,959View SEC Filing Icon  
12/30/2024Ecor1 Capital, LlcDirectorBuy58,988$14.47$853,556.3614,881,578View SEC Filing Icon  
12/26/2024Ecor1 Capital, LlcDirectorBuy16,692$14.38$240,030.9614,720,931View SEC Filing Icon  
12/24/2024Ecor1 Capital, LlcDirectorBuy11,958$14.12$168,846.9614,704,239View SEC Filing Icon  
1/8/2024Christopher AstleCFOSell1,431$11.22$16,055.826,503View SEC Filing Icon  
1/8/2024Kenneth GalbraithCEOSell5,706$11.22$64,021.3223,762View SEC Filing Icon  
1/8/2024Paul Andrew MooreInsiderSell2,339$11.22$26,243.587,367View SEC Filing Icon  
1/5/2024Christopher AstleCFOSell4,563$10.65$48,595.957,934View SEC Filing Icon  
1/5/2024Kenneth GalbraithCEOSell18,198$10.65$193,808.7029,468View SEC Filing Icon  
1/5/2024Paul Andrew MooreInsiderSell7,460$10.65$79,449.009,706View SEC Filing Icon  
12/11/2023Christopher AstleCFOSell886$9.13$8,089.181,997View SEC Filing Icon  
6/16/2023Ecor1 Capital, LlcMajor ShareholderBuy3,350,000$8.12$27,202,000.0013,437,473View SEC Filing Icon  
3/28/2023Ecor1 Capital, LlcMajor ShareholderBuy200,000$8.00$1,600,000.0010,087,473View SEC Filing Icon  
3/10/2023Neil A. KlompasCOOSell2,977$7.83$23,309.9117,032View SEC Filing Icon  
1/19/2023Ecor1 Capital, LlcMajor ShareholderBuy144,100$9.49$1,367,509.009,724,073View SEC Filing Icon  
1/17/2023Ecor1 Capital, LlcMajor ShareholderBuy440,000$9.80$4,312,000.009,376,973View SEC Filing Icon  
1/13/2023Ecor1 Capital, LlcMajor ShareholderBuy342,100$9.81$3,356,001.008,936,973View SEC Filing Icon  
1/10/2023Ecor1 Capital, LlcMajor ShareholderBuy920,000$7.65$7,038,000.008,488,573View SEC Filing Icon  
12/12/2022Christopher AstleCFOSell887$6.01$5,330.871,333View SEC Filing Icon  
See Full Table

SEC Filings (Institutional Ownership Changes) for Zymeworks (NYSE:ZYME)

92.89% of Zymeworks stock is owned by institutions. Institutional ownership can be a sign of analyst confidence in the fundamentals of the stock.

Institutional Buying and Selling by Quarter

This chart shows the instiutional buying and selling at ZYME by year and by quarter.

Skip Institutional Buying and Selling Chart and Table DataRead Chart Data in Institutional Trading History Table

Zymeworks Institutional Trading History

Reporting DateHedge FundShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
11/17/2025Dark Forest Capital Management LP37,167$0.64M0.0%-61.7%0.050%Search for SEC Filing on Google Icon
11/17/2025PharVision Advisers LLC17,790$0.30M0.2%N/A0.024%Search for SEC Filing on Google Icon
11/17/2025Vestal Point Capital LP1,765,000$30.15M1.4%+53.5%2.358%Search for SEC Filing on Google Icon
11/17/2025Samsara Biocapital LLC207,901$3.55M0.5%-33.0%0.278%Search for SEC Filing on Google Icon
11/17/2025Quarry LP2,942$50K0.0%N/A0.004%Search for SEC Filing on Google Icon
11/17/2025Qube Research & Technologies Ltd255,002$4.36M0.0%+264.9%0.341%Search for SEC Filing on Google Icon
11/17/2025Millennium Management LLC1,104,813$18.87M0.0%+851.6%1.476%Search for SEC Filing on Google Icon
11/17/2025MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.22,945$0.39M0.0%-14.6%0.031%Search for SEC Filing on Google Icon
11/17/2025Granahan Investment Management LLC345,331$5.90M0.2%-9.3%0.461%Search for SEC Filing on Google Icon
11/17/2025Brevan Howard Capital Management LP14,518$0.25M0.0%+36.6%0.019%Search for SEC Filing on Google Icon
11/17/2025Boothbay Fund Management LLC32,757$0.56M0.0%N/A0.044%Search for SEC Filing on Google Icon
11/17/2025Algert Global LLC207,926$3.55M0.1%+76.1%0.278%Search for SEC Filing on Google Icon
11/17/2025Ameriprise Financial Inc.75,928$1.30M0.0%N/A0.101%Search for SEC Filing on Google Icon
11/14/2025Schonfeld Strategic Advisors LLC107,788$1.84M0.0%N/A0.144%Search for SEC Filing on Google Icon
11/14/2025Creative Planning27,314$0.47M0.0%+7.6%0.036%Search for SEC Filing on Google Icon
11/14/2025Lazard Asset Management LLC15,308$0.26M0.0%N/A0.020%Search for SEC Filing on Google Icon
11/14/2025Raymond James Financial Inc.122,868$2.10M0.0%-1.3%0.164%Search for SEC Filing on Google Icon
11/14/2025Man Group plc158,616$2.71M0.0%+348.0%0.212%Search for SEC Filing on Google Icon
11/14/2025California State Teachers Retirement System35,231$0.60M0.0%-17.8%0.047%Search for SEC Filing on Google Icon
11/14/2025Acuta Capital Partners LLC80,143$1.37M1.4%-4.2%0.107%Search for SEC Filing on Google Icon
11/14/2025UBS AM A Distinct Business Unit of UBS Asset Management Americas LLC1,710,463$29.22M0.0%-30.5%2.286%Search for SEC Filing on Google Icon
11/14/2025Squarepoint Ops LLC219,948$3.76M0.0%+41.4%0.294%Search for SEC Filing on Google Icon
11/14/2025Prosight Management LP749,611$12.80M3.0%-42.8%1.002%Search for SEC Filing on Google Icon
11/13/2025Platinum Investment Management Ltd.124,784$2.13M0.1%-47.7%0.167%Search for SEC Filing on Google Icon
11/13/2025Arrowstreet Capital Limited Partnership313,753$5.36M0.0%N/A0.419%Search for SEC Filing on Google Icon
11/13/2025UBS Group AG51,841$0.89M0.0%-79.4%0.069%Search for SEC Filing on Google Icon
11/13/2025BNP Paribas Financial Markets15,460$0.26M0.0%+50.0%0.021%Search for SEC Filing on Google Icon
11/13/2025Mackenzie Financial Corp56,377$0.96M0.0%+164.0%0.075%Search for SEC Filing on Google Icon
11/13/2025Franklin Resources Inc.33,821$0.58M0.0%N/A0.045%Search for SEC Filing on Google Icon
11/13/2025Legal & General Group Plc28,369$0.49M0.0%-35.2%0.038%Search for SEC Filing on Google Icon
11/13/2025Russell Investments Group Ltd.57,448$0.98M0.0%+102.9%0.077%Search for SEC Filing on Google Icon
11/13/2025Schroder Investment Management Group161,486$2.78M0.0%-47.0%0.216%Search for SEC Filing on Google Icon
11/13/2025Vinva Investment Management Ltd14,594$0.25M0.0%N/A0.020%Search for SEC Filing on Google Icon
11/12/2025Barclays PLC199,023$3.40M0.0%+62.0%0.266%Search for SEC Filing on Google Icon
11/12/2025Dimensional Fund Advisors LP1,190,838$20.34M0.0%-0.1%1.591%Search for SEC Filing on Google Icon
11/12/2025Cresset Asset Management LLC10,134$0.17M0.0%-39.1%0.014%Search for SEC Filing on Google Icon
11/12/2025Picton Mahoney Asset Management206,322$3.52M0.0%-0.6%0.276%Search for SEC Filing on Google Icon
11/12/2025Intech Investment Management LLC16,982$0.29M0.0%-26.7%0.023%Search for SEC Filing on Google Icon
11/12/2025Fox Run Management L.L.C.16,145$0.28M0.0%N/A0.021%Search for SEC Filing on Google Icon
11/10/2025Optiver Holding B.V.1,510$26K0.0%N/A0.002%Search for SEC Filing on Google Icon
11/10/2025Ameritas Investment Partners Inc.4,164$71K0.0%-25.9%0.006%Search for SEC Filing on Google Icon
11/10/2025Citigroup Inc.117,804$2.01M0.0%-24.5%0.157%Search for SEC Filing on Google Icon
11/10/2025Hillsdale Investment Management Inc.216,422$3.70M0.1%+5.6%0.288%Search for SEC Filing on Google Icon
11/10/2025China Universal Asset Management Co. Ltd.13,176$0.23M0.0%-5.9%0.018%Search for SEC Filing on Google Icon
11/10/2025Jupiter Asset Management Ltd.350,660$5.99M0.1%-5.1%0.467%Search for SEC Filing on Google Icon
11/7/2025NEOS Investment Management LLC63,663$1.09M0.0%+22.8%0.085%Search for SEC Filing on Google Icon
11/7/2025Vanguard Group Inc.2,154,434$36.80M0.0%-12.6%2.866%Search for SEC Filing on Google Icon
11/7/2025JPMorgan Chase & Co.33,884$0.58M0.0%-92.3%0.045%Search for SEC Filing on Google Icon
11/7/2025Shell Asset Management Co.4,212$72K0.0%-54.7%0.006%Search for SEC Filing on Google Icon
11/6/2025ProShare Advisors LLC11,201$0.19M0.0%-11.6%0.015%Search for SEC Filing on Google Icon
11/4/2025Tejara Capital Ltd85,163$1.46M0.8%-57.5%0.113%Search for SEC Filing on Google Icon
11/3/2025AlphaQuest LLC8,471$0.15M0.0%-39.6%0.011%Search for SEC Filing on Google Icon
11/3/2025Federated Hermes Inc.182,847$3.12M0.0%+0.3%0.243%Search for SEC Filing on Google Icon
10/30/2025Strs Ohio40,900$0.70M0.0%-11.7%0.054%Search for SEC Filing on Google Icon
10/30/2025Universal Beteiligungs und Servicegesellschaft mbH30,432$0.52M0.0%+112.8%0.040%Search for SEC Filing on Google Icon
10/28/2025Campbell & CO Investment Adviser LLC32,493$0.56M0.0%+116.8%0.043%Search for SEC Filing on Google Icon
10/23/2025SG Americas Securities LLC13,624$0.23M0.0%+57.1%0.018%Search for SEC Filing on Google Icon
10/22/2025North Growth Management Ltd.82,000$1.41M0.2%-15.5%0.109%Search for SEC Filing on Google Icon
10/20/2025VIRGINIA RETIREMENT SYSTEMS ET Al55,975$0.96M0.0%+3.5%0.074%Search for SEC Filing on Google Icon
10/15/2025CWM LLC6,968$0.12M0.0%-18.7%0.009%Search for SEC Filing on Google Icon
10/7/2025Assenagon Asset Management S.A.1,326,774$22.66M0.0%+169.2%1.765%Search for SEC Filing on Google Icon
8/27/2025Squarepoint Ops LLC155,599$1.95M0.0%+144.6%0.207%Search for SEC Filing on Google Icon
8/15/2025Tower Research Capital LLC TRC 4,947$62K0.0%+29.6%0.007%Search for SEC Filing on Google Icon
8/15/2025Vestal Point Capital LP1,150,000$14.43M0.8%+130.0%1.530%Search for SEC Filing on Google Icon
8/15/2025Rubric Capital Management LP4,710,551$59.12M0.9%+8.6%6.267%Search for SEC Filing on Google Icon
8/15/2025Opaleye Management Inc.210,000$2.64M0.5%+20.0%0.279%Search for SEC Filing on Google Icon
8/15/2025Perceptive Advisors LLC1,275,274$16.01M1.4%-31.6%1.697%Search for SEC Filing on Google Icon
8/15/2025Man Group plc35,406$0.44M0.0%+226.1%0.047%Search for SEC Filing on Google Icon
8/15/2025EcoR1 Capital LLC22,970,388$288.28M17.1%+33.1%30.560%Search for SEC Filing on Google Icon
8/15/2025Engineers Gate Manager LP18,941$0.24M0.0%+52.8%0.025%Search for SEC Filing on Google Icon
8/15/2025BNP Paribas Financial Markets10,307$0.13M0.0%+157.7%0.014%Search for SEC Filing on Google Icon
8/15/2025Brevan Howard Capital Management LP10,628$0.13M0.0%N/A0.014%Search for SEC Filing on Google Icon
8/15/2025Bank of America Corp DE90,378$1.13M0.0%+45.5%0.120%Search for SEC Filing on Google Icon
8/15/2025Adage Capital Partners GP L.L.C.476,000$5.97M0.0%N/A0.633%Search for SEC Filing on Google Icon
8/14/2025Samsara Biocapital LLC310,300$3.89M0.8%-53.5%0.413%Search for SEC Filing on Google Icon
8/14/2025Jane Street Group LLC12,549$0.16M0.0%-90.8%0.017%Search for SEC Filing on Google Icon
8/14/2025California State Teachers Retirement System42,873$0.54M0.0%-2.1%0.057%Search for SEC Filing on Google Icon
8/14/2025Acuta Capital Partners LLC83,655$1.05M1.5%+22.2%0.111%Search for SEC Filing on Google Icon
8/14/2025Raymond James Financial Inc.124,435$1.56M0.0%+6.6%0.166%Search for SEC Filing on Google Icon
8/14/2025Redmile Group LLC4,150,627$52.09M5.5%-13.3%5.522%Search for SEC Filing on Google Icon
8/14/2025MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.26,863$0.34M0.0%-17.1%0.036%Search for SEC Filing on Google Icon
8/14/2025The Manufacturers Life Insurance Company 19,070$0.24M0.0%-6.8%0.025%Search for SEC Filing on Google Icon
8/14/2025Squarepoint Ops LLC155,599$1.95M0.0%+144.6%0.207%Search for SEC Filing on Google Icon
8/14/2025Qube Research & Technologies Ltd69,874$0.88M0.0%N/A0.093%Search for SEC Filing on Google Icon
8/14/2025AXA S.A.175,121$2.20M0.0%N/A0.233%Search for SEC Filing on Google Icon
8/13/2025Cresset Asset Management LLC16,638$0.21M0.0%-22.0%0.022%Search for SEC Filing on Google Icon
8/13/2025Tema Etfs LLC51,855$0.65M0.2%+57.1%0.069%Search for SEC Filing on Google Icon
8/13/2025Kennedy Capital Management LLC146,954$1.84M0.0%+7.8%0.196%Search for SEC Filing on Google Icon
8/13/2025Invesco Ltd.89,371$1.12M0.0%+14.3%0.119%Search for SEC Filing on Google Icon
8/13/2025Panagora Asset Management Inc.33,559$0.42M0.0%N/A0.045%Search for SEC Filing on Google Icon
8/13/2025Schroder Investment Management Group304,666$3.80M0.0%-5.4%0.405%Search for SEC Filing on Google Icon
8/13/2025Virtus Investment Advisers LLC7,178$90K0.0%-44.8%0.010%Search for SEC Filing on Google Icon
8/13/2025Tejara Capital Ltd200,150$2.51M1.2%+5.7%0.266%Search for SEC Filing on Google Icon
8/13/2025Norges Bank201,700$2.53M0.0%N/A0.268%Search for SEC Filing on Google Icon
8/13/2025Hsbc Holdings PLC36,497$0.46M0.0%N/A0.049%Search for SEC Filing on Google Icon
8/13/2025Russell Investments Group Ltd.28,312$0.36M0.0%+827.4%0.041%Search for SEC Filing on Google Icon
8/12/2025XTX Topco Ltd31,021$0.39M0.0%+53.5%0.045%Search for SEC Filing on Google Icon
8/12/2025Prudential Financial Inc.44,965$0.56M0.0%+5.6%0.065%Search for SEC Filing on Google Icon
8/12/2025Rhumbline Advisers86,083$1.08M0.0%+4.0%0.124%Search for SEC Filing on Google Icon
8/12/2025Legal & General Group Plc43,763$0.55M0.0%-6.5%0.063%Search for SEC Filing on Google Icon
Data available starting January 2016

See Full Table
Zymeworks logo
Zymeworks Inc., a clinical-stage biopharmaceutical company, discovers, develops, and commercializes biotherapeutics for the treatment of cancer. The company's lead product candidates include zanidatamab, a human epidermal growth factor receptor 2 (HER2) that is in Phase 1, Phase 2, and Phase 3 clinical trials, including certain ongoing pivotal clinical trials; and zanidatamab zovodotin, a HER2 -targeted antibody-drug conjugate that is in Phase 2 clinical trial for the treatment of advanced or metastatic HER2-expressing tumors. It also develops a pipeline of preclinical product candidates and discovery-stage programs in oncology, including immuno-oncology agents and other therapeutic areas. Zymeworks Inc. has strategic partnerships and collaborations with BeiGene, Ltd.; Celgene Corporation; Celgene Alpine Investment Co. LLC; GlaxoSmithKline Intellectual Property Development Limited; Daiichi Sankyo Co., Ltd.; Janssen Biotech, Inc.; LEO Pharma A/S; Iconic Therapeutics, Inc.; Merck Sharp & Dohme Research GmbH; and Atreca, Inc. Zymeworks Inc. was incorporated in 2003 and is based in Middletown, Delaware.
Read More on Zymeworks

Today's Range

Now: $26.52
Low: $25.91
High: $26.96

50 Day Range

MA: $20.00
Low: $16.46
High: $27.33

52 Week Range

Now: $26.52
Low: $9.03
High: $28.49

Volume

614,951 shs

Average Volume

692,099 shs

Market Capitalization

$1.98 billion

P/E Ratio

N/A

Dividend Yield

N/A

Beta

1.27

Who are the company insiders with the largest holdings of Zymeworks?

Zymeworks' top insider investors include:
  1. Ecor1 Capital, Llc (Director)
  2. Kenneth Galbraith (CEO)
  3. Paul Andrew Moore (Insider)
  4. Jeffrey T L Smith (EVP)
  5. Christopher Astle (CFO)
Learn More about top insider investors at Zymeworks.

Who are the major institutional investors of Zymeworks?

Zymeworks' top institutional investors include:
  1. Vanguard Group Inc. — 2.87%
  2. Vestal Point Capital LP — 2.36%
  3. UBS AM A Distinct Business Unit of UBS Asset Management Americas LLC — 2.29%
  4. Assenagon Asset Management S.A. — 1.77%
  5. Dimensional Fund Advisors LP — 1.59%
  6. Millennium Management LLC — 1.48%
Learn More about top institutional investors of Zymeworks stock.

Which major investors are selling Zymeworks stock?

During the last quarter, ZYME stock was sold by these institutional investors:
  1. UBS AM A Distinct Business Unit of UBS Asset Management Americas LLC
  2. Prosight Management LP
  3. JPMorgan Chase & Co.
  4. Vanguard Group Inc.
  5. UBS Group AG
  6. Schroder Investment Management Group
  7. Tejara Capital Ltd
  8. Platinum Investment Management Ltd.
During the previous year, company insiders that have sold Zymeworks company stock include:
  1. Ecor1 Capital, Llc (Director)
  2. Kenneth Galbraith (CEO)
  3. Paul Andrew Moore (Insider)
Learn More investors selling Zymeworks stock.

Which major investors are buying Zymeworks stock?

Within the previous quarter, ZYME stock was purchased by institutional investors including:
  1. Millennium Management LLC
  2. Assenagon Asset Management S.A.
  3. Vestal Point Capital LP
  4. Arrowstreet Capital Limited Partnership
  5. Qube Research & Technologies Ltd
  6. Man Group plc
  7. Schonfeld Strategic Advisors LLC
  8. Bank of America Corp DE